BR112014009006B8 - Compostos heterocíclicos e métodos de uso dos mesmos - Google Patents

Compostos heterocíclicos e métodos de uso dos mesmos

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Publication number
BR112014009006B8
BR112014009006B8 BR112014009006A BR112014009006A BR112014009006B8 BR 112014009006 B8 BR112014009006 B8 BR 112014009006B8 BR 112014009006 A BR112014009006 A BR 112014009006A BR 112014009006 A BR112014009006 A BR 112014009006A BR 112014009006 B8 BR112014009006 B8 BR 112014009006B8
Authority
BR
Brazil
Prior art keywords
methods
heterocyclic compounds
compounds
heterocyclic
compositions
Prior art date
Application number
BR112014009006A
Other languages
English (en)
Other versions
BR112014009006A2 (pt
BR112014009006B1 (pt
Inventor
Gang Liu
W Holladay Mark
W Rowbottom Martin
D Hocker Michael
J Hadd Michael
Shimin Xu
Original Assignee
Ambit Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ambit Biosciences Corp filed Critical Ambit Biosciences Corp
Publication of BR112014009006A2 publication Critical patent/BR112014009006A2/pt
Publication of BR112014009006B1 publication Critical patent/BR112014009006B1/pt
Publication of BR112014009006B8 publication Critical patent/BR112014009006B8/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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    • A61K31/425—Thiazoles
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    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

compostos heterocíclicos e métodos de uso dos mesmos trata-se de compostos heterocíclicos para o tratamento de doenças mediadas por csfir, flt3, kit, e/ou pdgfr(beta) quinase. trata-se, também, de composições farmacêuticas que compreendem os compostos e métodos de utilização dos compostos e composições.
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