BR0209777A - Formulações lìquidas estáveis - Google Patents

Formulações lìquidas estáveis

Info

Publication number
BR0209777A
BR0209777A BR0209777-0A BR0209777A BR0209777A BR 0209777 A BR0209777 A BR 0209777A BR 0209777 A BR0209777 A BR 0209777A BR 0209777 A BR0209777 A BR 0209777A
Authority
BR
Brazil
Prior art keywords
stable liquid
formulas
liquid formulations
stable
jobs
Prior art date
Application number
BR0209777-0A
Other languages
English (en)
Inventor
Tudor Arvinte
Pierre Francois Fauquex
Original Assignee
Novartis Ag
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Genentech Inc filed Critical Novartis Ag
Publication of BR0209777A publication Critical patent/BR0209777A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Abstract

"FORMULAçõES LìQUIDAS ESTáVEIS". A presente invenção fornece fórmulas líquidas estáveis dos anticorpos adequados para administração parenteral. Também são fornecidas soluções aquosas que têm altas concentrações de anticorpos terapêuticos que podem ser usados para produzir fórmulas líquidas terapêuticas. A presente invenção também refere-se a empregos, tais como empregos médicos, das fórmulas líquidas estáveis e processos para a produção das fórmulas líquidas estáveis.
BR0209777-0A 2001-05-31 2002-05-31 Formulações lìquidas estáveis BR0209777A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0113179.6A GB0113179D0 (en) 2001-05-31 2001-05-31 Organic compounds
PCT/EP2002/006016 WO2002096457A2 (en) 2001-05-31 2002-05-31 Stable liquid formulations of antibodies

Publications (1)

Publication Number Publication Date
BR0209777A true BR0209777A (pt) 2004-06-01

Family

ID=9915599

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209777-0A BR0209777A (pt) 2001-05-31 2002-05-31 Formulações lìquidas estáveis

Country Status (9)

Country Link
US (2) US7740842B2 (pt)
EP (1) EP1397159A2 (pt)
JP (1) JP4361280B2 (pt)
CN (1) CN100352500C (pt)
BR (1) BR0209777A (pt)
CA (1) CA2448345A1 (pt)
GB (1) GB0113179D0 (pt)
IL (1) IL158802A0 (pt)
WO (1) WO2002096457A2 (pt)

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Also Published As

Publication number Publication date
JP4361280B2 (ja) 2009-11-11
CA2448345A1 (en) 2002-12-05
CN1537015A (zh) 2004-10-13
JP2004532262A (ja) 2004-10-21
EP1397159A2 (en) 2004-03-17
US7740842B2 (en) 2010-06-22
WO2002096457A3 (en) 2003-02-13
WO2002096457A2 (en) 2002-12-05
US20040170623A1 (en) 2004-09-02
IL158802A0 (en) 2004-05-12
CN100352500C (zh) 2007-12-05
US20060127395A1 (en) 2006-06-15
GB0113179D0 (en) 2001-07-25

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