BR0014803A - Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição de diagnóstico - Google Patents
Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição de diagnósticoInfo
- Publication number
- BR0014803A BR0014803A BR0014803-2A BR0014803A BR0014803A BR 0014803 A BR0014803 A BR 0014803A BR 0014803 A BR0014803 A BR 0014803A BR 0014803 A BR0014803 A BR 0014803A
- Authority
- BR
- Brazil
- Prior art keywords
- amino acids
- peptides
- ser
- peptide
- composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rehabilitation Therapy (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"PEPTìDEO, COMPOSIçãO FARMACêUTICA, USO DE UM OU MAIS DOS PEPTìDEOS, E, COMPOSIçãO DE DIAGNóSTICO". A invenção diz respeito a um peptìdeo modificado derivado de H-Arg-Ser-Phe-Thr-Leu-Ala-Ser-Ser-Glu-Thr-Gly-Val-Gly-OH tendo a fórmula geral (II): Q-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13-Z. Na fórmula geral (II), A1 até A13 correspondem com os aminoácidos da Fórmula (I), Q corresponde com H e Z corresponde com OH. As modificações de acordo com a presente invenção são selecionadas de um ou mais dos grupos a, b ou c, consistindo de a) substituição de 1 a 6, preferivelmente de 1 a 4 aminoácidos em A1 até A13 com aminoácidos não naturais ou <225> aminoácidos; b) substituição de uma ou mais ligações de amida com ligações de amida reduzidas ou isósteros de etileno; c) substituições em Q e/ou Z e, opcionalmente, d) substituição de aminoácidos naturais até um total de 6 modificações. Os peptídeos podem ser usados para induzir a indução de tolerância em pacientes que sofrem de doenças autoimunes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99203427 | 1999-10-18 | ||
PCT/EP2000/010230 WO2001029081A1 (en) | 1999-10-18 | 2000-10-12 | Modified peptides and peptidomimetics for use in immunotherapy |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0014803A true BR0014803A (pt) | 2002-06-11 |
Family
ID=8240756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0014803-2A BR0014803A (pt) | 1999-10-18 | 2000-10-12 | Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição de diagnóstico |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1226167A1 (pt) |
JP (1) | JP2003512388A (pt) |
KR (1) | KR20020047245A (pt) |
CN (1) | CN1379786A (pt) |
AR (1) | AR026068A1 (pt) |
AU (1) | AU780238B2 (pt) |
BR (1) | BR0014803A (pt) |
CA (1) | CA2386398A1 (pt) |
CO (1) | CO5271650A1 (pt) |
CZ (1) | CZ20021356A3 (pt) |
HK (1) | HK1046693A1 (pt) |
HU (1) | HUP0203504A3 (pt) |
IL (1) | IL148778A0 (pt) |
MX (1) | MXPA02003520A (pt) |
NO (1) | NO20021763L (pt) |
NZ (1) | NZ518256A (pt) |
PE (1) | PE20010692A1 (pt) |
PL (1) | PL354590A1 (pt) |
RU (1) | RU2002113107A (pt) |
SK (1) | SK6842002A3 (pt) |
TR (1) | TR200201036T2 (pt) |
WO (1) | WO2001029081A1 (pt) |
ZA (1) | ZA200202577B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002951212A0 (en) * | 2002-09-04 | 2002-09-19 | Monash University | A method of modulating cellular activity and molecules for use therein |
US20100240137A1 (en) * | 2006-04-06 | 2010-09-23 | Purdue Research Foundation | Derivatization-enhanced analysis of amino acids and peptides |
EP2114462B1 (en) * | 2006-12-21 | 2013-06-05 | Universite De Geneve | Compounds for fluorescence imaging |
WO2009092381A1 (en) | 2008-01-23 | 2009-07-30 | Herlev Hospital, Region Hovedstaden | Ykl-40 as a general marker for non-specific disease |
US8580520B2 (en) | 2008-09-15 | 2013-11-12 | Herlev Hospital | YKL-40 as a marker for gastrointestinal cancers |
AU2015342767B2 (en) * | 2014-11-07 | 2021-05-13 | Kineta Chronic Pain, Llc | Modifications and uses of conotoxin peptides |
EP3466963A1 (en) * | 2017-10-05 | 2019-04-10 | Suigeneris Farmacosmetics, S.L. | Anticancer peptides and uses thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL115744A (en) * | 1994-10-27 | 2000-07-16 | Akzo Nobel Nv | Peptides comprising a subsequence of human cartilage glycoprotein - 39 |
TW575583B (en) * | 1996-04-24 | 2004-02-11 | Akzo Nobel Nv | Novel peptides suitable for use in antigen specific immunosuppressive therapy |
SK166798A3 (en) * | 1996-06-07 | 1999-07-12 | Zeneca Ltd | Peptide derivatives, process for their preparation, pharmaceutical composition them containing, and their use |
IL122233A (en) * | 1996-12-06 | 2001-04-30 | Akzo Nobel Nv | Method of generating monoclonal antibodies to cell wall and pharmaceutical preparations and diagnostic agents containing them |
-
2000
- 2000-10-12 NZ NZ518256A patent/NZ518256A/en unknown
- 2000-10-12 WO PCT/EP2000/010230 patent/WO2001029081A1/en not_active Application Discontinuation
- 2000-10-12 AU AU11396/01A patent/AU780238B2/en not_active Ceased
- 2000-10-12 CN CN00814418A patent/CN1379786A/zh active Pending
- 2000-10-12 RU RU2002113107/15A patent/RU2002113107A/ru not_active Application Discontinuation
- 2000-10-12 HU HU0203504A patent/HUP0203504A3/hu unknown
- 2000-10-12 CZ CZ20021356A patent/CZ20021356A3/cs unknown
- 2000-10-12 KR KR1020027004940A patent/KR20020047245A/ko not_active Application Discontinuation
- 2000-10-12 CA CA002386398A patent/CA2386398A1/en not_active Abandoned
- 2000-10-12 TR TR2002/01036T patent/TR200201036T2/xx unknown
- 2000-10-12 EP EP00972790A patent/EP1226167A1/en not_active Withdrawn
- 2000-10-12 PL PL00354590A patent/PL354590A1/xx not_active Application Discontinuation
- 2000-10-12 MX MXPA02003520A patent/MXPA02003520A/es unknown
- 2000-10-12 IL IL14877800A patent/IL148778A0/xx unknown
- 2000-10-12 BR BR0014803-2A patent/BR0014803A/pt not_active IP Right Cessation
- 2000-10-12 JP JP2001531879A patent/JP2003512388A/ja not_active Withdrawn
- 2000-10-12 SK SK684-2002A patent/SK6842002A3/sk not_active Application Discontinuation
- 2000-10-17 PE PE2000001107A patent/PE20010692A1/es not_active Application Discontinuation
- 2000-10-18 AR ARP000105458A patent/AR026068A1/es unknown
- 2000-10-18 CO CO00079334A patent/CO5271650A1/es not_active Application Discontinuation
-
2002
- 2002-04-02 ZA ZA200202577A patent/ZA200202577B/en unknown
- 2002-04-15 NO NO20021763A patent/NO20021763L/no not_active Application Discontinuation
- 2002-11-13 HK HK02108208.9A patent/HK1046693A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
SK6842002A3 (en) | 2002-09-10 |
MXPA02003520A (es) | 2002-08-20 |
CN1379786A (zh) | 2002-11-13 |
HK1046693A1 (zh) | 2003-01-24 |
HUP0203504A2 (hu) | 2003-04-28 |
WO2001029081A1 (en) | 2001-04-26 |
EP1226167A1 (en) | 2002-07-31 |
NO20021763D0 (no) | 2002-04-15 |
CO5271650A1 (es) | 2003-04-30 |
IL148778A0 (en) | 2002-09-12 |
CA2386398A1 (en) | 2001-04-26 |
RU2002113107A (ru) | 2004-01-10 |
AU780238B2 (en) | 2005-03-10 |
JP2003512388A (ja) | 2003-04-02 |
TR200201036T2 (tr) | 2002-08-21 |
ZA200202577B (en) | 2003-09-23 |
PL354590A1 (en) | 2004-01-26 |
KR20020047245A (ko) | 2002-06-21 |
AR026068A1 (es) | 2002-12-26 |
NZ518256A (en) | 2004-01-30 |
AU1139601A (en) | 2001-04-30 |
NO20021763L (no) | 2002-04-15 |
PE20010692A1 (es) | 2001-07-06 |
HUP0203504A3 (en) | 2005-03-29 |
CZ20021356A3 (cs) | 2002-07-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR950703999A (ko) | 변성된 인슐린-유사 성장인자(modified insulin-like growth factors) | |
GR3031919T3 (en) | PEPTIDES OF HUMAN p53 PROTEIN FOR USE IN HUMAN T CELL RESPONSE INDUCING COMPOSITIONS, AND HUMAN p53 PROTEIN-SPECIFIC CYTOTOXIC T-LYMPHOCYTES. | |
BRPI0109494B8 (pt) | muteína de fator viii, sequência de dna, vetor, processo para produção da muteína de fator viii, composição farmacêutica e uso da muteína do fator viii | |
BR9910639A (pt) | Drogas anti-angiogênicas compreendendo peptìdeo | |
BR0208183A (pt) | Peptìdeo modificado por wt1 | |
BR0309877A (pt) | Peptìdeos estimuladores de tecido conectivo | |
ES2178000T3 (es) | Composiciones y metodos para tratar infecciones usando analogos de indolicidina. | |
ATE413189T1 (de) | Verfahren und zusammensetzungen zur behinderung der vervielfältigung von hiv-1 | |
RU2012106150A (ru) | Вариантные формы уратоксидазы и их применение | |
PT593754E (pt) | Peptidos do virus do papiloma humano para uso em composicoes indutoras de uma reaccao das celulas t no homem | |
BR0209434A (pt) | Peptìdeos antimicrobianos e composições | |
BR9607336A (pt) | Composições de aminoácidos e utilidades das mesmas em nutrição clinica | |
BR9807618A (pt) | Análogo de fator xdelta, dna recombinante codificante para um análogo de fator xdelta, células transformadas, preparação, uso da mesma, e, processos para produzir uma preparação contendo análogo de fator xdelta recombinante purificado e análogo de fator xa. | |
MX9703642A (es) | Metodos para el tratamiento de esclerosis multiple utilizando analogos de peptido en la posicion 91 de la proteina basica de mielina humana. | |
BR0013638A (pt) | Novas moléculas semelhantes a interferon beta | |
BR9811755A (pt) | Peptìdeo, processo para o tratamento da obesidade em um animal, uso de um peptìdeo, e, composição farmacêutica | |
BR9607628A (pt) | Mólecula proteinácea biologicamente isolada, molécula recombinante, fragmento de peptìdeo, molécula de ácido nucleico, composição farmacêutica, e, processos para preparar uma molécula recombinante e para induzir a proliferação astroglial em um mamìfero | |
BR0111506A (pt) | Complexos de droga macromoleculares e composições contendo os mesmos | |
BR0009472A (pt) | Antagonistas de lhrh com propriedades desolubilidade aperfeiçoadas | |
BR0014803A (pt) | Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição de diagnóstico | |
BR0116122A (pt) | Peptìdeos e/ou proteìnas bem como seu uso para preparar uma composição farmacêutica, terapêutica e/ou preventiva | |
CA2334941A1 (en) | Tnf-derived peptides for use in treating oedema | |
EA199700381A1 (ru) | Диароматические соединения пропинила или диенила, промежуточные соединения, фармацевтические и косметические композиции на основе указанных соединений и применение косметических композиций | |
FR2846883B1 (fr) | Composition cosmetique comprenant, comme ingredient actif, au moins un peptide et utilisation de ce peptide | |
KR960000921A (ko) | 칼시토닌 유도체 및 그 용도 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A,7A E 8A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |