BR0209434A - Peptìdeos antimicrobianos e composições - Google Patents

Peptìdeos antimicrobianos e composições

Info

Publication number
BR0209434A
BR0209434A BR0209434-7A BR0209434A BR0209434A BR 0209434 A BR0209434 A BR 0209434A BR 0209434 A BR0209434 A BR 0209434A BR 0209434 A BR0209434 A BR 0209434A
Authority
BR
Brazil
Prior art keywords
compositions
antimicrobial peptides
peptides
cyclic peptides
antimicrobian
Prior art date
Application number
BR0209434-7A
Other languages
English (en)
Inventor
M Reza Ghadiri
Hui-Sun Kim
Sara Fernandez-Lopez
Keith Wilcoxex
Original Assignee
Scripps Research Inst
M Reza Ghadiri
Hui-Sun Kim
Sara Fernandez-Lopez
Keith Wilcoxex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst, M Reza Ghadiri, Hui-Sun Kim, Sara Fernandez-Lopez, Keith Wilcoxex filed Critical Scripps Research Inst
Publication of BR0209434A publication Critical patent/BR0209434A/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/126Tetrapeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Composite Materials (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"PEPTìDEOS ANTIMICROBIANOS E COMPOSIçõES". A presente invenção provê novos agentes antimicrobianos e composições que incluem peptídeos cíclicos tendo uma seq³ência de D- e L-<244>-aminoácidos alternados. Alternativamente os peptídeos cíclicos são feitos de beta-aminoácidos.
BR0209434-7A 2001-05-04 2002-05-06 Peptìdeos antimicrobianos e composições BR0209434A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28899001P 2001-05-04 2001-05-04
PCT/US2002/014329 WO2002090503A2 (en) 2001-05-04 2002-05-06 Anti-microbial peptides and compositions

Publications (1)

Publication Number Publication Date
BR0209434A true BR0209434A (pt) 2006-02-07

Family

ID=23109523

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209434-7A BR0209434A (pt) 2001-05-04 2002-05-06 Peptìdeos antimicrobianos e composições

Country Status (7)

Country Link
US (1) US20050107289A1 (pt)
EP (1) EP1402001A4 (pt)
JP (1) JP2004535392A (pt)
BR (1) BR0209434A (pt)
CA (1) CA2446322A1 (pt)
MX (1) MXPA03010103A (pt)
WO (1) WO2002090503A2 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7550558B2 (en) * 2001-06-01 2009-06-23 Fundacao De Ampara A Pesquiso Do Estado De Sao Paolo (Fapesp) Antimicrobial peptides and methods for identifying and using such peptides
FI20021763A0 (fi) * 2002-10-03 2002-10-03 Karyon Oy Ab Ltd Uusia terapeuttisesti aktiivisia aineita ja niiden käyttö
WO2006014570A2 (en) * 2004-07-06 2006-02-09 3D Matrix, Inc. Purified amphilic peptide compositions and uses thereof
CA2597191C (en) * 2005-02-09 2014-04-01 Helix Biomedix Inc. Antimicrobial hexapeptides
KR20100102750A (ko) 2005-04-25 2010-09-24 메사추세츠 인스티튜트 오브 테크놀로지 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법
US9162005B2 (en) * 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
US8198403B2 (en) * 2005-05-26 2012-06-12 Board Of Regents, The University Of Texas System Diameter-selective reversible closable peptides
WO2007008618A2 (en) * 2005-07-13 2007-01-18 University Of South Carolina Sterilization using high-pressure carbon dioxide
WO2007055578A1 (en) * 2005-11-11 2007-05-18 Leids Universitair Medisch Centrum Cyclic antimicrobial peptides derived from lactoferrin
GB0526120D0 (en) * 2005-12-22 2006-02-01 Novabiotics Ltd Therapeutic peptides
RU2463308C2 (ru) * 2005-12-22 2012-10-10 НоваБиотикс Лимитед Циклические противомикробные пептиды
US9181303B2 (en) * 2005-12-22 2015-11-10 Novabiotics Limited Treatment of bacterial infections with cyclic antimicrobial peptides
JP2009535338A (ja) 2006-04-25 2009-10-01 マサチューセッツ・インスティテュート・オブ・テクノロジー 汚染因子、体液または他の実体の動きに影響を及ぼし、そして/あるいは他の生理学的状態に影響を及ぼすための組成物および方法
GB0702021D0 (en) * 2007-02-02 2007-03-14 Novabiotics Ltd Peptides and their use
US8366652B2 (en) 2007-08-17 2013-02-05 The Invention Science Fund I, Llc Systems, devices, and methods including infection-fighting and monitoring shunts
US9187330B2 (en) 2008-09-15 2015-11-17 The Invention Science Fund I, Llc Tubular nanostructure targeted to cell membrane
SG194405A1 (en) 2008-10-06 2013-11-29 3 D Matrix Ltd Tissue occluding agent
WO2010051667A1 (zh) * 2008-11-10 2010-05-14 复旦大学 一种环肽纳米管药物组合物及其应用
WO2010057275A1 (en) * 2008-11-24 2010-05-27 Sydney West Area Health Services Cyclic peptides and uses thereof
US20120041286A1 (en) 2008-12-04 2012-02-16 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems, devices, and methods including implantable devices with anti-microbial properties
US8975368B2 (en) * 2009-08-13 2015-03-10 The United States Of America, As Represented By The Secretary Of The Navy Methods for preparing linked peptide rings and peptide nanotubes obtained thereby
WO2011072482A1 (en) 2009-12-14 2011-06-23 The University Of Hong Kong Nano cancer barrier device(ncbd) to immobilize and inhibit the division of metastic cancer stem cells
JP2014528253A (ja) * 2011-10-17 2014-10-27 ディー.アイ.アール.テクノロジーズ (ディテクション アイアール)リミテッドD.I.R.Technologies(Detection Ir) Ltd. サンプル中の微生物の存在を検出するための方法
AU2014248252A1 (en) * 2013-04-02 2015-10-29 M. Reza Ghadiri Uses of cyclic peptides for treating and preventing atherosclerosis
JP6502352B2 (ja) 2013-08-22 2019-04-17 アーチ・バイオサージェリー・インコーポレイテッド 流体の移動を制御するための移植可能なメッシュ
JP6807831B2 (ja) 2014-05-21 2021-01-06 エントラーダ セラピューティクス,インコーポレイテッド 細胞膜透過性ペプチド、並びにこの作製方法及び使用方法
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
SG11201610918RA (en) * 2014-07-01 2017-01-27 Agency Science Tech & Res Peptides and uses thereof
EP3185880B1 (en) 2014-08-27 2020-02-12 Ohio State Innovation Foundation Improved peptidyl calcineurin inhibitors
WO2018098226A1 (en) 2016-11-22 2018-05-31 Ohio State Innovation Foundation Bicyclic peptidyl inhibitor of tumor necrosis factor-alpha
WO2019148194A2 (en) 2018-01-29 2019-08-01 Ohio State Innovation Foundation Peptidyl inhibitors of calcineurin-nfat interaction
EP3755351A4 (en) 2018-02-22 2021-11-24 Entrada Therapeutics, Inc. COMPOSITIONS AND TREATMENT METHODS FOR MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY
EP3790890A4 (en) 2018-05-09 2022-03-02 Ohio State Innovation Foundation CYCLIC PEPTIDES OF CELL PENETRATION WITH ONE OR MORE HYDROPHOBIC RESIDUES

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010535A1 (en) * 1993-10-14 1995-04-20 The Scripps Research Institute Cyclic peptide tube
US5821329A (en) * 1996-06-06 1998-10-13 Tanabe Seiyaku Co., Ltd. Cyclic peptide inhibitors of β1 and β2 integrin-mediated adhesion
US6277818B1 (en) * 1998-10-29 2001-08-21 Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
US5985837A (en) * 1998-07-08 1999-11-16 Basf Aktiengesellschaft Dolastatin 15 derivatives

Also Published As

Publication number Publication date
CA2446322A1 (en) 2002-11-14
EP1402001A4 (en) 2006-05-24
US20050107289A1 (en) 2005-05-19
MXPA03010103A (es) 2004-03-10
JP2004535392A (ja) 2004-11-25
WO2002090503A3 (en) 2004-01-29
WO2002090503A2 (en) 2002-11-14
EP1402001A2 (en) 2004-03-31

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