BG63974B1 - Карбапенеми, използването им и междинни съединения за тях - Google Patents

Карбапенеми, използването им и междинни съединения за тях Download PDF

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Publication number
BG63974B1
BG63974B1 BG103699A BG10369999A BG63974B1 BG 63974 B1 BG63974 B1 BG 63974B1 BG 103699 A BG103699 A BG 103699A BG 10369999 A BG10369999 A BG 10369999A BG 63974 B1 BG63974 B1 BG 63974B1
Authority
BG
Bulgaria
Prior art keywords
methyl
dioxolen
hydroxyethyl
carboxylate
pivaloyloxymethyl
Prior art date
Application number
BG103699A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG103699A (en
Inventor
Hiroshi Matsui
Masayasu Kasai
Original Assignee
Kyoto Pharmaceutical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharmaceutical Industries, Ltd. filed Critical Kyoto Pharmaceutical Industries, Ltd.
Publication of BG103699A publication Critical patent/BG103699A/xx
Publication of BG63974B1 publication Critical patent/BG63974B1/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG103699A 1997-02-07 1999-08-30 Карбапенеми, използването им и междинни съединения за тях BG63974B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2567197 1997-02-07
JP24890397 1997-09-12
PCT/JP1998/000446 WO1998034936A1 (fr) 1997-02-07 1998-02-02 Composes de carbapenem, leur utilisation et composes intermediaires de celui-ci

Publications (2)

Publication Number Publication Date
BG103699A BG103699A (en) 2000-06-30
BG63974B1 true BG63974B1 (bg) 2003-08-29

Family

ID=26363329

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103699A BG63974B1 (bg) 1997-02-07 1999-08-30 Карбапенеми, използването им и междинни съединения за тях

Country Status (24)

Country Link
US (1) US6342494B1 (pt)
EP (1) EP0987267B1 (pt)
KR (1) KR100530478B1 (pt)
CN (1) CN1107067C (pt)
AT (1) ATE239728T1 (pt)
AU (1) AU740327C (pt)
BG (1) BG63974B1 (pt)
BR (1) BR9807187A (pt)
CA (1) CA2280273A1 (pt)
CZ (1) CZ272099A3 (pt)
DE (1) DE69814381T2 (pt)
ES (1) ES2198689T3 (pt)
HK (1) HK1026896A1 (pt)
HU (1) HUP0000952A3 (pt)
ID (1) ID22543A (pt)
NO (1) NO993774L (pt)
NZ (1) NZ337532A (pt)
PL (1) PL335048A1 (pt)
RU (1) RU2178792C2 (pt)
SK (1) SK108099A3 (pt)
TR (1) TR199901887T2 (pt)
TW (1) TW580499B (pt)
WO (1) WO1998034936A1 (pt)
YU (1) YU37299A (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040176350A1 (en) * 2001-05-21 2004-09-09 Hiroshi Matsui Carbapenem compound
US7205291B2 (en) * 2001-11-05 2007-04-17 Dainippon Sumitomo Pharma Co., Ltd. Carbapenem compounds
US7468364B2 (en) * 2003-04-08 2008-12-23 Dainippon Sumitomo Pharma Co., Ltd. Carbapenem compounds
EP1785426A4 (en) * 2004-09-03 2008-02-20 Dainippon Sumitomo Pharma Co NEW CARBAPENEM DERIVATIVE
US20090029964A1 (en) * 2005-03-25 2009-01-29 Makoto Sunagawa Novel carbapenem compound
KR100869165B1 (ko) 2007-09-13 2008-11-19 조동옥 메로페넴의 개선된 제조방법
CN101868460A (zh) * 2007-11-23 2010-10-20 国际药品工业株式会社 2-芳基甲基吖丁啶-碳青霉烯-3-羧酸酯衍生物或其盐、其制备方法以及包含上述的药物组合物
CN103504481A (zh) * 2013-10-11 2014-01-15 红塔烟草(集团)有限责任公司 一种带抗菌层烟嘴的电子卷烟

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
FI81576C (fi) * 1984-12-25 1990-11-12 Sankyo Co Foerfarande foer framstaellning av derivat av 6-(1-hydroxietyl)-2-(1,2-disubstituerade-4-pyrrolidinyltio)-2- karbapenem-3-karboxylsyra, vilka aer anvaendbara som laekemedel.
IE60588B1 (en) * 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
AU644008B2 (en) * 1990-08-10 1993-12-02 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production and use
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
US5360798A (en) * 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
NZ324447A (en) 1995-12-21 1999-08-30 Sankyo Co 1-methyl-carbapenem substituted by a 4-pyrrolidinylthio group and medicaments
JP3671529B2 (ja) 1996-07-29 2005-07-13 ソニー株式会社 熱転写形記録装置及び記録方法

Also Published As

Publication number Publication date
KR20000070809A (ko) 2000-11-25
EP0987267A1 (en) 2000-03-22
AU740327C (en) 2002-05-09
HUP0000952A3 (en) 2000-12-28
DE69814381T2 (de) 2003-12-04
ES2198689T3 (es) 2004-02-01
HUP0000952A2 (hu) 2000-10-28
YU37299A (sh) 2002-06-19
ID22543A (id) 1999-11-04
US6342494B1 (en) 2002-01-29
EP0987267A4 (en) 2000-05-31
ATE239728T1 (de) 2003-05-15
AU5680698A (en) 1998-08-26
CZ272099A3 (cs) 1999-11-17
NZ337532A (en) 2001-06-29
KR100530478B1 (ko) 2005-11-23
HK1026896A1 (en) 2000-12-29
TR199901887T2 (xx) 1999-12-21
BR9807187A (pt) 2000-01-25
CA2280273A1 (en) 1998-08-13
NO993774L (no) 1999-09-30
WO1998034936A1 (fr) 1998-08-13
CN1107067C (zh) 2003-04-30
AU740327B2 (en) 2001-11-01
DE69814381D1 (de) 2003-06-12
PL335048A1 (en) 2000-03-27
NO993774D0 (no) 1999-08-04
CN1252072A (zh) 2000-05-03
SK108099A3 (en) 2000-03-13
RU2178792C2 (ru) 2002-01-27
TW580499B (en) 2004-03-21
BG103699A (en) 2000-06-30
EP0987267B1 (en) 2003-05-07

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