BR9807187A - Composto de carbapenem, seu uso e composto intermediário para o mesmo - Google Patents

Composto de carbapenem, seu uso e composto intermediário para o mesmo

Info

Publication number
BR9807187A
BR9807187A BR9807187-4A BR9807187A BR9807187A BR 9807187 A BR9807187 A BR 9807187A BR 9807187 A BR9807187 A BR 9807187A BR 9807187 A BR9807187 A BR 9807187A
Authority
BR
Brazil
Prior art keywords
compound
infectious diseases
carbapenem
carbapenem compound
prophylaxis
Prior art date
Application number
BR9807187-4A
Other languages
English (en)
Inventor
Hiroshi Matsui
Masayasu Kasai
Original Assignee
Kyoto Pharma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharma Ind filed Critical Kyoto Pharma Ind
Publication of BR9807187A publication Critical patent/BR9807187A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Patente de Invenção:<B>"COMPOSTO DE CARBAPENEM, SEU USO E COMPOSTO INTERMEDIáRIO PARA O MESMO"<D>. Um composto de carbapenem de fórmula (I) na qual cada símbolo é como definido no relatório descritivo e um seu sal farmaceuticamente aceitável. O composto de carbapenem (I)e um sau sal farmaceuticamente aceitável da presente invenção apresentam absorção superior do trato digestivo por administração oral e suficiente atividade antibacteriana contra uma ampla variedade de espécies bacteriais. Desse modo, são extremamente úteis como agentes para a profilaxia e o tratamento de doenças infecciosas, particularmente doenças infecciosas bacterianas. Os ditos agentes para a profilaxia e o tratamento de doenças infecciosas provocadas por bactérias (por exemplo, doenças inflamatórias do trato biliar, infecção do trato urinário e assemelhados) em animais de sangue quente inclusive de seres humanos (por exemplo, cães, gatos, vacas, cavalos, ratos, camundongos e assemelhados).
BR9807187-4A 1997-02-07 1998-02-02 Composto de carbapenem, seu uso e composto intermediário para o mesmo BR9807187A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2567197 1997-02-07
JP24890397 1997-09-12
PCT/JP1998/000446 WO1998034936A1 (fr) 1997-02-07 1998-02-02 Composes de carbapenem, leur utilisation et composes intermediaires de celui-ci

Publications (1)

Publication Number Publication Date
BR9807187A true BR9807187A (pt) 2000-01-25

Family

ID=26363329

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9807187-4A BR9807187A (pt) 1997-02-07 1998-02-02 Composto de carbapenem, seu uso e composto intermediário para o mesmo

Country Status (24)

Country Link
US (1) US6342494B1 (pt)
EP (1) EP0987267B1 (pt)
KR (1) KR100530478B1 (pt)
CN (1) CN1107067C (pt)
AT (1) ATE239728T1 (pt)
AU (1) AU740327C (pt)
BG (1) BG63974B1 (pt)
BR (1) BR9807187A (pt)
CA (1) CA2280273A1 (pt)
CZ (1) CZ272099A3 (pt)
DE (1) DE69814381T2 (pt)
ES (1) ES2198689T3 (pt)
HK (1) HK1026896A1 (pt)
HU (1) HUP0000952A3 (pt)
ID (1) ID22543A (pt)
NO (1) NO993774L (pt)
NZ (1) NZ337532A (pt)
PL (1) PL335048A1 (pt)
RU (1) RU2178792C2 (pt)
SK (1) SK108099A3 (pt)
TR (1) TR199901887T2 (pt)
TW (1) TW580499B (pt)
WO (1) WO1998034936A1 (pt)
YU (1) YU37299A (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0400444A3 (en) * 2001-05-21 2007-02-28 Kyoto Pharmaceutical Ind Carbapenem compound, pharmaceutical compositions containing them and their use
KR100945706B1 (ko) * 2001-11-05 2010-03-05 다이닛본 스미토모 세이야꾸 가부시끼가이샤 신규 카르바페넴 화합물
US7468364B2 (en) * 2003-04-08 2008-12-23 Dainippon Sumitomo Pharma Co., Ltd. Carbapenem compounds
US20070265242A1 (en) * 2004-09-03 2007-11-15 Makoto Sunagawa Novel Carbapenem Compound
JPWO2006103999A1 (ja) * 2005-03-25 2008-09-04 大日本住友製薬株式会社 新規なカルバペネム化合物
KR100869165B1 (ko) 2007-09-13 2008-11-19 조동옥 메로페넴의 개선된 제조방법
JP2011504495A (ja) * 2007-11-23 2011-02-10 クジェ ファーマシューティカル インダストリアル カンパニー リミテッド ２−アリールメチルアゼチジン−カルバペネム−３−カルボン酸エステル誘導体またはその塩、その製造方法及びそれを含む医薬組成物
CN103504481A (zh) * 2013-10-11 2014-01-15 红塔烟草(集团)有限责任公司 一种带抗菌层烟嘴的电子卷烟

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
FI81576C (fi) * 1984-12-25 1990-11-12 Sankyo Co Foerfarande foer framstaellning av derivat av 6-(1-hydroxietyl)-2-(1,2-disubstituerade-4-pyrrolidinyltio)-2- karbapenem-3-karboxylsyra, vilka aer anvaendbara som laekemedel.
IE60588B1 (en) 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
AU644008B2 (en) * 1990-08-10 1993-12-02 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production and use
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
US5360798A (en) * 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
WO1997023483A1 (en) 1995-12-21 1997-07-03 Sankyo Company, Limited 1-methylcarbapenem derivatives
JP3671529B2 (ja) 1996-07-29 2005-07-13 ソニー株式会社 熱転写形記録装置及び記録方法

Also Published As

Publication number Publication date
EP0987267A1 (en) 2000-03-22
YU37299A (sh) 2002-06-19
SK108099A3 (en) 2000-03-13
EP0987267B1 (en) 2003-05-07
HUP0000952A2 (hu) 2000-10-28
WO1998034936A1 (fr) 1998-08-13
KR100530478B1 (ko) 2005-11-23
ES2198689T3 (es) 2004-02-01
EP0987267A4 (en) 2000-05-31
TW580499B (en) 2004-03-21
NO993774D0 (no) 1999-08-04
HUP0000952A3 (en) 2000-12-28
ID22543A (id) 1999-11-04
BG103699A (en) 2000-06-30
US6342494B1 (en) 2002-01-29
CZ272099A3 (cs) 1999-11-17
AU740327C (en) 2002-05-09
HK1026896A1 (en) 2000-12-29
ATE239728T1 (de) 2003-05-15
TR199901887T2 (xx) 1999-12-21
AU5680698A (en) 1998-08-26
NZ337532A (en) 2001-06-29
DE69814381T2 (de) 2003-12-04
DE69814381D1 (de) 2003-06-12
NO993774L (no) 1999-09-30
KR20000070809A (ko) 2000-11-25
AU740327B2 (en) 2001-11-01
CN1252072A (zh) 2000-05-03
CA2280273A1 (en) 1998-08-13
BG63974B1 (bg) 2003-08-29
PL335048A1 (en) 2000-03-27
CN1107067C (zh) 2003-04-30
RU2178792C2 (ru) 2002-01-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1908 DE 31/07/2007.