BG29573A3 - Method of obtaining of benzodiazepin derivatives - Google Patents

Method of obtaining of benzodiazepin derivatives

Info

Publication number
BG29573A3
BG29573A3 BG031601A BG3160175A BG29573A3 BG 29573 A3 BG29573 A3 BG 29573A3 BG 031601 A BG031601 A BG 031601A BG 3160175 A BG3160175 A BG 3160175A BG 29573 A3 BG29573 A3 BG 29573A3
Authority
BG
Bulgaria
Prior art keywords
obtaining
derivatives
benzodiazepin
benzodiazepin derivatives
proven
Prior art date
Application number
BG031601A
Other languages
Bulgarian (bg)
English (en)
Inventor
Jiban Chakrabarti
David Tupper
Original Assignee
Lilly Industries Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG29573(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Limited filed Critical Lilly Industries Limited
Publication of BG29573A3 publication Critical patent/BG29573A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG031601A 1974-11-26 1975-11-26 Method of obtaining of benzodiazepin derivatives BG29573A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
BG29573A3 true BG29573A3 (en) 1980-12-12

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
BG031601A BG29573A3 (en) 1974-11-26 1975-11-26 Method of obtaining of benzodiazepin derivatives

Country Status (30)

Country Link
JP (1) JPS6044314B2 (ro)
AR (1) AR221203A1 (ro)
AT (1) AT351547B (ro)
AU (1) AU506340B2 (ro)
BE (1) BE835932A (ro)
BG (1) BG29573A3 (ro)
CA (1) CA1075687A (ro)
CH (2) CH613454A5 (ro)
CS (1) CS236753B2 (ro)
DD (1) DD123343A5 (ro)
DE (1) DE2552403C2 (ro)
DK (1) DK146887C (ro)
ES (1) ES443011A1 (ro)
FR (1) FR2292479A1 (ro)
GB (1) GB1533235A (ro)
HK (1) HK58681A (ro)
HU (1) HU172493B (ro)
IE (1) IE42564B1 (ro)
IL (1) IL48502A (ro)
KE (1) KE3163A (ro)
MY (1) MY8200149A (ro)
NL (1) NL186088C (ro)
NZ (1) NZ179335A (ro)
PH (2) PH11669A (ro)
PL (1) PL100135B1 (ro)
RO (1) RO69912A (ro)
SE (2) SE421209B (ro)
SU (2) SU629879A3 (ro)
YU (1) YU298375A (ro)
ZA (1) ZA757344B (ro)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
ES2153373T3 (es) * 1992-05-29 2001-03-01 Lilly Co Eli Derivados de tienobenzodiazepina para el tratamiento de trastornos del sistema nervioso central.
AU700078B2 (en) * 1995-11-01 1998-12-17 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
CA2302409A1 (en) 1997-09-02 1999-03-11 Hiroshi Yasumatsu Condensed thiophene compounds and pharmaceutical use thereof
PL199016B1 (pl) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Sposób wytwarzania olanzapiny
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
DE10301923B3 (de) * 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Verfahren und Zwischenprodukte zur Herstellung von Olanzapin
AR047460A1 (es) * 2004-01-27 2006-01-18 Synthon Bv Proceso para la fabricacion de acetato de 2-metil-4-(4-metil-1-piperazinil)-10h-tieno[2,3-b][1,5]benzodiazepina (acetato de olanzapina)
AR048272A1 (es) 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
CA2565683C (en) * 2004-06-30 2013-04-02 Athersys, Inc. Substituted azepine derivatives as serotonin receptor modulators
EP2292624A1 (en) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Process for the purification of olanzapine

Also Published As

Publication number Publication date
AU506340B2 (en) 1979-12-20
DE2552403A1 (de) 1976-08-12
AU8685875A (en) 1977-05-26
JPS5176296A (en) 1976-07-01
NL186088B (nl) 1990-04-17
GB1533235A (en) 1978-11-22
ES443011A1 (es) 1977-07-01
BE835932A (fr) 1976-05-25
AR221203A1 (es) 1981-01-15
CH613455A5 (en) 1979-09-28
DE2552403C2 (de) 1986-06-19
DD123343A5 (ro) 1976-12-12
YU298375A (en) 1982-10-31
MY8200149A (en) 1982-12-31
IL48502A (en) 1980-01-31
KE3163A (en) 1981-10-16
PL100135B1 (pl) 1978-09-30
ATA898275A (de) 1979-01-15
RO69912A (ro) 1980-08-15
SU629879A3 (ru) 1978-10-25
SE421209B (sv) 1981-12-07
CH613454A5 (en) 1979-09-28
IE42564B1 (en) 1980-09-10
NZ179335A (en) 1978-11-13
DK524175A (da) 1976-05-27
SE7812194L (sv) 1978-11-27
PH11669A (en) 1978-05-19
SE7513185L (sv) 1976-05-27
IL48502A0 (en) 1976-01-30
FR2292479A1 (fr) 1976-06-25
DK146887C (da) 1984-07-09
CA1075687A (en) 1980-04-15
AT351547B (de) 1979-07-25
CS236753B2 (en) 1985-05-15
SU626702A3 (ru) 1978-09-30
DK146887B (da) 1984-01-30
ZA757344B (en) 1976-11-24
NL186088C (nl) 1990-09-17
JPS6044314B2 (ja) 1985-10-02
IE42564L (en) 1976-05-26
NL7513833A (nl) 1976-05-31
PH24534A (en) 1990-08-03
FR2292479B1 (ro) 1978-07-28
HK58681A (en) 1981-12-04
HU172493B (hu) 1978-09-28
SE429045B (sv) 1983-08-08

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