AU2001264595A1 - Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their uses - Google Patents
Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their usesInfo
- Publication number
- AU2001264595A1 AU2001264595A1 AU2001264595A AU6459501A AU2001264595A1 AU 2001264595 A1 AU2001264595 A1 AU 2001264595A1 AU 2001264595 A AU2001264595 A AU 2001264595A AU 6459501 A AU6459501 A AU 6459501A AU 2001264595 A1 AU2001264595 A1 AU 2001264595A1
- Authority
- AU
- Australia
- Prior art keywords
- phenanthridinones
- sulfonamide
- carbamide derivatives
- carbamide
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20525900P | 2000-05-19 | 2000-05-19 | |
US60205259 | 2000-05-19 | ||
PCT/US2001/015571 WO2001090077A1 (fr) | 2000-05-19 | 2001-05-15 | Derives de sulfonamide et de carbamide de 6(5h) phenanthridinones et utilisations de ceux-ci |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001264595A1 true AU2001264595A1 (en) | 2001-12-03 |
Family
ID=22761477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001264595A Abandoned AU2001264595A1 (en) | 2000-05-19 | 2001-05-15 | Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their uses |
Country Status (3)
Country | Link |
---|---|
US (1) | US6723733B2 (fr) |
AU (1) | AU2001264595A1 (fr) |
WO (1) | WO2001090077A1 (fr) |
Families Citing this family (70)
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US6476048B1 (en) | 1999-12-07 | 2002-11-05 | Inotek Pharamaceuticals Corporation | Substituted phenanthridinones and methods of use thereof |
US6723733B2 (en) | 2000-05-19 | 2004-04-20 | Guilford Pharmaceuticals, Inc. | Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses |
US7151102B2 (en) | 2000-10-30 | 2006-12-19 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
CA2330350A1 (fr) | 2000-12-05 | 2002-06-05 | Chemokine Therapeutics Corporation | Produits pour traiter des maladies a mediation chemokinique |
WO2002045702A2 (fr) * | 2000-12-05 | 2002-06-13 | Chemokine Therapeutics Corporation | Traitement des maladies induites par les chimiokines |
US6956035B2 (en) | 2001-08-31 | 2005-10-18 | Inotek Pharmaceuticals Corporation | Isoquinoline derivatives and methods of use thereof |
AUPS137402A0 (en) * | 2002-03-26 | 2002-05-09 | Fujisawa Pharmaceutical Co., Ltd. | Novel tricyclic compounds |
DE60335359D1 (de) | 2002-04-30 | 2011-01-27 | Kudos Pharm Ltd | Phthalazinonderivate |
EP1603567A4 (fr) * | 2003-02-28 | 2006-10-18 | Inotek Pharmaceuticals Corp | Derives de benzamide tetracyclique et leurs procedes d'utilisation |
US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
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MX2007010335A (es) * | 2005-02-25 | 2007-11-06 | Inotek Pharmaceuticals Corp | Compuestos de isoquinolina y metodos de uso de los mismos. |
EP1850848A4 (fr) * | 2005-02-25 | 2008-02-20 | Inotek Pharmaceuticals Corp | Composes tetracycliques de sulfonamide et methodes d'utilisation desdits composes |
CA2614930A1 (fr) * | 2005-07-11 | 2007-01-18 | Wyeth | Inhibiteurs de glutamate aggrecanase |
ZA200800907B (en) * | 2005-07-18 | 2010-04-28 | Bipar Sciences Inc | Treatment of cancer |
EP1937268A4 (fr) * | 2005-08-24 | 2009-07-22 | Inotek Pharmaceuticals Corp | Analogues d'indenoisoquinolinone et leurs procedes d'utilisation |
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DK2061765T3 (en) * | 2006-09-01 | 2015-01-26 | Senhwa Biosciences Inc | Serine-threonine protein kinase AND PARP-MODULATOR |
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US8143447B2 (en) * | 2006-09-05 | 2012-03-27 | Bipar Sciences, Inc. | Treatment of cancer |
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US10669383B2 (en) * | 2006-10-31 | 2020-06-02 | Evonik Corporation | Spheronized polymer particles |
TWI433674B (zh) | 2006-12-28 | 2014-04-11 | Infinity Discovery Inc | 環杷明(cyclopamine)類似物類 |
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GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
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US9486449B2 (en) | 2007-10-09 | 2016-11-08 | Malka COHEN-ARMON | Cancer therapy |
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AR070221A1 (es) | 2008-01-23 | 2010-03-25 | Astrazeneca Ab | Derivados de ftalazinona inhibidores de polimerasas, composiciones farmaceuticas que los contienen y usos de los mismos para prevenir y/o tratar tumores cancerigenos,lesiones isquemicas y otras enfermedades asociadas. |
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WO2010081778A1 (fr) * | 2009-01-17 | 2010-07-22 | Universität Zürich | Bloqueurs de parp pour la prévention et le traitement d'un cancer gastrique induit par helicobacter pylori |
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WO2011058367A2 (fr) | 2009-11-13 | 2011-05-19 | Astrazeneca Ab | Test de diagnostic pour prédire la sensibilité à un traitement par un inhibiteur de poly(adp-ribose) polymérase |
US20130116284A1 (en) | 2010-05-10 | 2013-05-09 | Radikal Therapeutics Inc. | Lipoic acid and nitroxide derivatives and uses thereof |
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AU2014214325B2 (en) * | 2013-02-06 | 2018-06-07 | Merck Patent Gmbh | Substituted carboxylic acid derivatives as aggrecanase inhibitors for the treatment of osteoarthritis |
GB201311361D0 (en) | 2013-06-26 | 2013-08-14 | Pimco 2664 Ltd | Compounds and their therapeutic use |
US10005733B2 (en) | 2014-12-17 | 2018-06-26 | Pimco 2664 Limited | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use |
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CN106316953B (zh) * | 2015-06-15 | 2019-02-01 | 浙江工业大学 | 一种6-氰基菲啶类化合物的合成方法 |
PT3325623T (pt) | 2015-07-23 | 2019-09-04 | Inst Curie | Utilização de uma combinação de molécula dbait e de inibidores de parp para o tratamento do cancro |
CN105131974B (zh) * | 2015-07-28 | 2017-04-12 | 江苏和成新材料有限公司 | 一种菲啶酮结构的杂环可聚合液晶化合物及其制备方法 |
GB201519573D0 (en) | 2015-11-05 | 2015-12-23 | King S College London | Combination |
WO2018022851A1 (fr) | 2016-07-28 | 2018-02-01 | Mitobridge, Inc. | Méthode de traitement de lésions rénales aiguës. |
AU2017355402A1 (en) | 2016-11-02 | 2019-05-30 | Health Research, Inc. | Combination treatment with antibody-drug conjugates and PARP inhibitors |
WO2018162439A1 (fr) | 2017-03-08 | 2018-09-13 | Onxeo | Nouveau biomarqueur prédictif de la sensibilité à un traitement du cancer avec une molécule dbait |
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CN111201215B (zh) * | 2017-08-07 | 2024-01-26 | 国立大学法人广岛大学 | 新型酰胺系化合物、使用了该化合物的Pin1抑制剂、炎症性疾病的治疗剂及癌症的治疗剂 |
JP2021515580A (ja) | 2018-03-13 | 2021-06-24 | オンクセオOnxeo | がんの治療における獲得耐性に対抗するdbait分子 |
CN110256346A (zh) * | 2019-07-03 | 2019-09-20 | 浙江省医学科学院 | 具有brd4蛋白抑制作用的菲啶酮类化合物及制备方法和应用 |
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-
2001
- 2001-05-15 US US09/854,455 patent/US6723733B2/en not_active Expired - Fee Related
- 2001-05-15 WO PCT/US2001/015571 patent/WO2001090077A1/fr active Application Filing
- 2001-05-15 AU AU2001264595A patent/AU2001264595A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001090077A1 (fr) | 2001-11-29 |
US20020006927A1 (en) | 2002-01-17 |
US6723733B2 (en) | 2004-04-20 |
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