ES8601706A1 - Una composicion farmaceutica - Google Patents

Una composicion farmaceutica

Info

Publication number
ES8601706A1
ES8601706A1 ES532317A ES532317A ES8601706A1 ES 8601706 A1 ES8601706 A1 ES 8601706A1 ES 532317 A ES532317 A ES 532317A ES 532317 A ES532317 A ES 532317A ES 8601706 A1 ES8601706 A1 ES 8601706A1
Authority
ES
Spain
Prior art keywords
delivery system
drug delivery
system utilizing
drug
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532317A
Other languages
English (en)
Other versions
ES532317A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/495,240 external-priority patent/US4474752A/en
Priority claimed from US06/495,239 external-priority patent/US4478822A/en
Priority claimed from US06/495,238 external-priority patent/US4474751A/en
Priority claimed from US06/495,321 external-priority patent/US4474753A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES532317A0 publication Critical patent/ES532317A0/es
Publication of ES8601706A1 publication Critical patent/ES8601706A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Abstract

PROCEDIMIENTO PARA PREPARAR UNA COMPOSICION FARMAEUTICA ACUOSA. COMPRENDE: A) DEPOSITAR EN UN RECIPIENTE DE 10% A 50% EN PESO, CALCULADO SOBRE EL PESO TOTAL DE LA COMPOSICION, DE UN POLIMERO DE FORMULA (I); B) AGITAR EL RECIPIENTE DE LA ETAPA A); C) TAPAR EL RECIPIENTE E INTRODUCIRLO EN UN RECINTO FRIO A UNOS 0 A 10C PARA LOGRAR LA TOTAL DISOLUCION DEL POLIMERO; D) DISOLVER EN LA SOLUCION C) UNA CANTIDAD FARMACOLOGICAMENTE EFECTIVA DE UN FARMACO O AGENTE DE DIAGNOSTICO Y ADITIVOS; E) AJUSTAR EL PH DE LA SOLUCION ANTERIOR A ENTRE 2 Y 9 MEDIANTE UN ACIDO O BASE, PARA LOGRAR QUE LA COMPOSICION SEA LIQUIDA A TEMPERATURA AMBIENTE O POR DEBAJO DE ELLA; SIENDO W UN NUMERO ENTERO DE 2 A 6, QUE CONTIENE DE 40 A 80% DE POLI(OXIETILENO) Y DE 20 A 60% DE POLI(OXIPROPILENO) Y TIENE UN PESO MOLECULAR DE 7.000 A 50.000; X E Y SON NUMEROS ENTEROS.
ES532317A 1983-05-16 1984-05-09 Una composicion farmaceutica Expired ES8601706A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/495,240 US4474752A (en) 1983-05-16 1983-05-16 Drug delivery system utilizing thermosetting gels
US06/495,239 US4478822A (en) 1983-05-16 1983-05-16 Drug delivery system utilizing thermosetting gels
US06/495,238 US4474751A (en) 1983-05-16 1983-05-16 Ophthalmic drug delivery system utilizing thermosetting gels
US06/495,321 US4474753A (en) 1983-05-16 1983-05-16 Topical drug delivery system utilizing thermosetting gels

Publications (2)

Publication Number Publication Date
ES532317A0 ES532317A0 (es) 1985-11-16
ES8601706A1 true ES8601706A1 (es) 1985-11-16

Family

ID=27504371

Family Applications (1)

Application Number Title Priority Date Filing Date
ES532317A Expired ES8601706A1 (es) 1983-05-16 1984-05-09 Una composicion farmaceutica

Country Status (5)

Country Link
EP (1) EP0126684B1 (es)
CA (1) CA1224148A (es)
DE (1) DE3484969D1 (es)
DK (1) DK164481C (es)
ES (1) ES8601706A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT83095B (en) * 1985-07-30 1987-12-23 Int Minerals & Chem Corp Method for the stabilization of growth promoting hormones using polyoxyethylene-polyoxypropylene copolymers
DE3700911C2 (de) * 1986-01-17 2001-05-17 West Pharm Serv Drug Res Ltd System zur Zuführung eines Arzneimittels oder eines Diagnostikums
US4780320A (en) * 1986-04-29 1988-10-25 Pharmetrix Corp. Controlled release drug delivery system for the periodontal pocket
GB2203039B (en) * 1987-03-02 1990-10-24 American Cyanamid Co Stable ophthalmic preparations containing acetazolamide
US6436425B1 (en) 1988-11-16 2002-08-20 Mdv Technologies, Inc. Method and non-gelling composition for inhibiting post-surgical adhesions
IL95942A0 (en) * 1989-10-13 1991-07-18 Syntex Inc Collagen-containing ophthalmic formulation
US5256396A (en) * 1990-01-24 1993-10-26 Colgate-Palmolive Company Topical composition
US5252318A (en) * 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
CA2044878C (en) * 1990-08-07 2000-12-26 Tacey X. Viegas Thermally reversible and irreversible gels
US5346703A (en) 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
GB2248842A (en) * 1990-10-16 1992-04-22 American Cyanamid Co Film-forming polymer compositions
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
US6277410B1 (en) * 1992-10-08 2001-08-21 Supratek Pharma Inc. Copolymer compositions for oral delivery
JPH10500148A (ja) 1994-03-04 1998-01-06 ユニバーシティ オブ ワシントン ブロック及びグラフトコポリマー並びにそれに関連する方法
US5770627A (en) * 1995-08-16 1998-06-23 University Of Washington Hydrophobically-modified bioadhesive polyelectrolytes and methods relating thereto
US6426415B1 (en) 1997-09-03 2002-07-30 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity
US6197785B1 (en) 1997-09-03 2001-03-06 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity
US6291425B1 (en) 1999-09-01 2001-09-18 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage
US6514983B1 (en) 1997-09-03 2003-02-04 Guilford Pharmaceuticals Inc. Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage
US6635642B1 (en) 1997-09-03 2003-10-21 Guilford Pharmaceuticals Inc. PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same
US6346536B1 (en) 1997-09-03 2002-02-12 Guilford Pharmaceuticals Inc. Poly(ADP-ribose) polymerase inhibitors and method for treating neural or cardiovascular tissue damage using the same
US6861411B1 (en) 1997-12-02 2005-03-01 Pfizer, Inc. Method of treating eye infections with azithromycin
US6395749B1 (en) 1998-05-15 2002-05-28 Guilford Pharmaceuticals Inc. Carboxamide compounds, methods, and compositions for inhibiting PARP activity
US6387902B1 (en) 1998-12-31 2002-05-14 Guilford Pharmaceuticals, Inc. Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP
US6239113B1 (en) 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
AU2001264595A1 (en) 2000-05-19 2001-12-03 Guilford Pharmaceuticals Inc. Sulfonamide and carbamide derivatives of 6(5h)phenanthridinones and their uses
AU2001275085A1 (en) 2000-06-01 2001-12-11 Guilford Pharmaceuticals Inc. Methods, compounds and compositions for treating gout
WO2016141182A1 (en) 2015-03-03 2016-09-09 Yee Richard W Compositions and methods for treating ocular diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579465A (en) * 1967-10-16 1971-05-18 Wyandotte Chemicals Corp Aqueous gels of polyoxyethylated polyoxypropylene glycol adducts of ethylene diamine
CA1072413A (en) * 1976-07-13 1980-02-26 West Laboratories Poloxamer gel systems with gelling temperatures higher than room temperature

Also Published As

Publication number Publication date
ES532317A0 (es) 1985-11-16
CA1224148A (en) 1987-07-14
EP0126684A2 (en) 1984-11-28
DK233884A (da) 1984-11-17
EP0126684A3 (en) 1986-02-05
DK164481B (da) 1992-07-06
DK164481C (da) 1992-11-16
DK233884D0 (da) 1984-05-11
DE3484969D1 (de) 1991-10-02
EP0126684B1 (en) 1991-08-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303