ATE497504T1 - Aminoderivate von b-homoandrostanen und b- heteroandrostanen - Google Patents

Aminoderivate von b-homoandrostanen und b- heteroandrostanen

Info

Publication number
ATE497504T1
ATE497504T1 AT07729767T AT07729767T ATE497504T1 AT E497504 T1 ATE497504 T1 AT E497504T1 AT 07729767 T AT07729767 T AT 07729767T AT 07729767 T AT07729767 T AT 07729767T AT E497504 T1 ATE497504 T1 AT E497504T1
Authority
AT
Austria
Prior art keywords
homoandrostanes
heteroandrostanes
amino derivatives
derivatives
amino
Prior art date
Application number
AT07729767T
Other languages
English (en)
Inventor
Alberto Cerri
Barbara Moro
Maco Torri
Giulio Carzana
Giuseppe Bianchi
Mara Ferrandi
Patrizia Ferrari
Maria Pia Zappavigna
Leonardo Banfi
Giuseppe Giacalone
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of ATE497504T1 publication Critical patent/ATE497504T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/004—Expansion of ring B by one atom, e.g. B homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AT07729767T 2006-06-23 2007-05-31 Aminoderivate von b-homoandrostanen und b- heteroandrostanen ATE497504T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06116001 2006-06-23
PCT/EP2007/055366 WO2007147713A1 (en) 2006-06-23 2007-05-31 Amino derivatives of b-homoandrostanes and b-heteroandrostanes

Publications (1)

Publication Number Publication Date
ATE497504T1 true ATE497504T1 (de) 2011-02-15

Family

ID=37603055

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07729767T ATE497504T1 (de) 2006-06-23 2007-05-31 Aminoderivate von b-homoandrostanen und b- heteroandrostanen

Country Status (21)

Country Link
US (1) US8022203B2 (de)
EP (1) EP2032593B1 (de)
JP (1) JP4664433B2 (de)
KR (1) KR101446166B1 (de)
CN (1) CN101479291B (de)
AR (1) AR061561A1 (de)
AT (1) ATE497504T1 (de)
AU (1) AU2007263117B2 (de)
BR (1) BRPI0713439A2 (de)
CA (1) CA2654354C (de)
CY (1) CY1112012T1 (de)
DE (1) DE602007012348D1 (de)
DK (1) DK2032593T3 (de)
EA (1) EA014333B1 (de)
ES (1) ES2359544T3 (de)
HK (1) HK1134097A1 (de)
MX (1) MX2008016425A (de)
PL (1) PL2032593T3 (de)
SI (1) SI2032593T1 (de)
TW (1) TWI372762B (de)
WO (1) WO2007147713A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2422603T3 (es) * 2007-05-31 2013-09-12 Shionogi & Co Compuestos oxiimino y el uso de estos
WO2009122997A1 (ja) * 2008-04-02 2009-10-08 株式会社カネカ （ｓ）－３－（１－シアノ－１，１－ジフェニルメチル）－ピロリジンの製造法
US8518934B2 (en) 2008-06-11 2013-08-27 Shonogi & Co., Ltd. Oxycarbamoyl compounds and the use thereof
US20120028945A1 (en) * 2009-03-23 2012-02-02 Patrizia Ferrari 5-Beta, 14-Beta-Androstane Derivatives Useful For The Treatment Of Proteinuria, Glomerulosclerosis And Renal Failure
GB201104199D0 (en) 2011-03-11 2011-04-27 Syngenta Participations Ag Plant growth regulator compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2806029A (en) * 1956-07-16 1957-09-10 Searle & Co 3-oxygenated 12a-aza-c-homopregnane-12, 20-diones and congeners
US3136584A (en) * 1963-01-25 1964-06-09 Whitlock Associates Inc Bulk material hopper unloader
US3328408A (en) * 1964-01-30 1967-06-27 Smith 6-azaestranes, intermediates and process
DE19633349A1 (de) * 1996-08-19 1998-02-26 Sigma Tau Ind Farmaceuti Neue 6-Hydroxy- und 6-Oxo-androstan-Derivate, die auf das kardiovaskuläre System wirken und pharmazeutische Zusammensetzungen, die diese enthalten
US6825208B2 (en) * 2001-08-20 2004-11-30 Bristol-Myers Squibb Pharma Company Tetrahydroquinoline derivatives as antithrombotic agents
US7053076B2 (en) * 2001-08-29 2006-05-30 Xenoport, Inc. Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
JP5065019B2 (ja) * 2004-06-24 2012-10-31 ウィスコンシン アルムニ リサーチ ファンデイション 新生糖ランダム化及びジギトキシン類似体

Also Published As

Publication number Publication date
JP4664433B2 (ja) 2011-04-06
EP2032593A1 (de) 2009-03-11
ES2359544T3 (es) 2011-05-24
KR20090023730A (ko) 2009-03-05
AR061561A1 (es) 2008-09-03
KR101446166B1 (ko) 2014-10-01
AU2007263117A1 (en) 2007-12-27
JP2009541410A (ja) 2009-11-26
TW200817427A (en) 2008-04-16
EA200970046A1 (ru) 2009-06-30
AU2007263117A2 (en) 2009-03-12
SI2032593T1 (sl) 2011-05-31
CN101479291B (zh) 2012-09-19
EA014333B1 (ru) 2010-10-29
US20090209506A1 (en) 2009-08-20
EP2032593B1 (de) 2011-02-02
DE602007012348D1 (de) 2011-03-17
CA2654354A1 (en) 2007-12-27
TWI372762B (en) 2012-09-21
DK2032593T3 (da) 2011-05-16
WO2007147713A1 (en) 2007-12-27
HK1134097A1 (de) 2010-04-16
CN101479291A (zh) 2009-07-08
AU2007263117B2 (en) 2012-05-24
PL2032593T3 (pl) 2011-05-31
US8022203B2 (en) 2011-09-20
CY1112012T1 (el) 2015-11-04
BRPI0713439A2 (pt) 2012-03-06
CA2654354C (en) 2014-12-23
MX2008016425A (es) 2009-01-21

Similar Documents

Publication Publication Date Title
ATE531720T1 (de) Aza-benzofuranylverbindungen und anwendungsverfahren dafür
DE602007010981D1 (de) Cycloalkylaminsubstituierte isochinolin- und isochinolinonderivate
DK1984322T3 (da) Benzamid- og heteroarenderivater
CR10815A (es) Nuevos derivados de isoquinolina e isoquinolinona sustituidos
CY2014012I1 (el) Χορηγηση αναστολεων διπεπτιδυλοπεπτιδασης
BRPI0716300A2 (pt) Artigo e mistura
ATE511509T1 (de) Azaindolylverbindungen und anwendungsverfahren
DK1940839T3 (da) Pyridopyrimidione Inhibitors of P13Ka
DE602005017635D1 (de) Harzzusammensetzung und formteil daraus
DE602007004401D1 (de) Primerzusammensetzung und beschichteter artikel
ATE534660T1 (de) Peptidsequenzen und zusammensetzungen
DE602006020061D1 (de) Mucin-glycoprotein und anwendung davon
DE502007002308D1 (de) Direktanbindung von Wurstclip- und Wurstfördereinrichtung
ATE420081T1 (de) Trifluormethylbenzamidderivate und therapeutische verwendungen dafür
ATE402154T1 (de) Monohydrochloridsalz von 1-ä3-ä3-(4- chlorphenyl)propoxyüpropylüpiperidin
DE602006003063D1 (de) Tripeptid- und tetrapeptidsulfone
CR9850A (es) Carbamoylbenzotriazole derivatives as inhibitors of lipases and phospholipases
DE602006015540D1 (de) Durchführung und buchse
DE602006013874D1 (de) Wässrige emulsion und klebstofffzusammensetzung
DE602006017183D1 (de) Benzimidazolderivat und anwendung davon
ATE460162T1 (de) Neue kristallformen von irinotecan-hydrochlorid
ATE540682T1 (de) Kombination von triazin-derivaten und insulin- sekretionsstimulatoren
BRPI0719228A2 (pt) Composição estabilizada de prostaglandina e
ATE468342T1 (de) Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen
ATE497504T1 (de) Aminoderivate von b-homoandrostanen und b- heteroandrostanen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 2032593

Country of ref document: EP