ATE460162T1 - Neue kristallformen von irinotecan-hydrochlorid - Google Patents

Neue kristallformen von irinotecan-hydrochlorid

Info

Publication number
ATE460162T1
ATE460162T1 AT06803842T AT06803842T ATE460162T1 AT E460162 T1 ATE460162 T1 AT E460162T1 AT 06803842 T AT06803842 T AT 06803842T AT 06803842 T AT06803842 T AT 06803842T AT E460162 T1 ATE460162 T1 AT E460162T1
Authority
AT
Austria
Prior art keywords
crystal forms
irinotecan hydrochloride
new crystal
irinotecan
hydrochloride
Prior art date
Application number
AT06803842T
Other languages
English (en)
Inventor
Shu-Ping Chen
Piin-Jye Harn
Original Assignee
Scinopharm Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scinopharm Singapore Pte Ltd filed Critical Scinopharm Singapore Pte Ltd
Application granted granted Critical
Publication of ATE460162T1 publication Critical patent/ATE460162T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT06803842T 2005-09-20 2006-09-19 Neue kristallformen von irinotecan-hydrochlorid ATE460162T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71882705P 2005-09-20 2005-09-20
PCT/US2006/036437 WO2007035709A2 (en) 2005-09-20 2006-09-19 Novel crystal forms of irinotecan hydrochloride

Publications (1)

Publication Number Publication Date
ATE460162T1 true ATE460162T1 (de) 2010-03-15

Family

ID=37889452

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06803842T ATE460162T1 (de) 2005-09-20 2006-09-19 Neue kristallformen von irinotecan-hydrochlorid

Country Status (14)

Country Link
US (1) US7435818B2 (de)
EP (2) EP2082741A1 (de)
JP (1) JP5119153B2 (de)
KR (1) KR101150504B1 (de)
CN (1) CN101277694B (de)
AR (1) AR056082A1 (de)
AT (1) ATE460162T1 (de)
AU (1) AU2006292328B2 (de)
BR (1) BRPI0616308A2 (de)
CA (1) CA2623117C (de)
DE (1) DE602006012871D1 (de)
ES (1) ES2343204T3 (de)
NZ (1) NZ566807A (de)
WO (1) WO2007035709A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101318964B (zh) * 2007-06-07 2010-12-15 上海迪赛诺医药发展有限公司 盐酸伊立替康新晶型及其制备方法
US7572803B2 (en) * 2007-10-25 2009-08-11 The Christus Stehlin Foundation For Cancer Research Hydrated crystalline esters of camptothecin
IT1391757B1 (it) * 2008-11-11 2012-01-27 Antibioticos Spa Irinotecan cloridrato cristallino e metodi per la sua preparazione
US8546573B2 (en) 2009-11-18 2013-10-01 Cadila Healthcare Limited Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate
WO2012007952A1 (en) * 2010-07-12 2012-01-19 Hetero Research Foundation Novel polymorph of irinotecan hydrochloride
CN102311443B (zh) * 2011-08-24 2014-07-16 上海北卡医药技术有限公司 盐酸伊立替康的新晶型及其制备方法
CN102617584B (zh) * 2012-03-14 2013-10-16 海南锦瑞制药股份有限公司 一种盐酸伊立替康化合物及其药物组合物
CN102850363B (zh) * 2012-09-18 2013-07-10 山东罗欣药业股份有限公司 盐酸伊立替康化合物及其药物组合物
MX2015014486A (es) * 2013-04-15 2016-07-21 Regeneron Pharma Marcadores de respuesta de células tumorales a la terapia.
CN105713004A (zh) * 2016-03-23 2016-06-29 杭州华东医药集团新药研究院有限公司 一种高品质盐酸伊立替康三水合物晶型的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019790A (ja) 1983-07-14 1985-01-31 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体
AR015190A1 (es) * 1997-10-23 2001-04-18 Smithkline Beecham Corp Un polimorfo cristalino de 1,3-diciclopropilmetil-8-aminoxantina, procedimiento para su preparacion, composiciones farmaceuticas que lo contienen y su usopara la manufactura de un medicamento
CZ20022332A3 (cs) * 2000-01-07 2003-01-15 Transform Pharmaceuticals, Inc. Sestava vzorků
KR20040091083A (ko) * 2002-03-01 2004-10-27 파마시아 이탈리아 에스.피.에이. 이리노테칸 히드로클로라이드의 결정성 다형체
CZ20022250A3 (cs) * 2002-06-27 2004-02-18 Pliva-Lachema A. S. Způsob výroby irinotekanu
BRPI0407791A (pt) 2003-02-25 2006-02-14 Yakult Honsa Kk método para preparação de polimorfismo de cloridrato de irinotecan
WO2006016203A1 (en) * 2004-08-09 2006-02-16 Shilpa Medicare Limited An improved process for the preparation of irinotecan hydrochloride trihydrate
US20060046993A1 (en) * 2004-09-01 2006-03-02 Pharmacia Italia S.P.A. Crystalline polymorphic form of irinotecan hydrochloride
PL1846412T3 (pl) * 2005-02-07 2010-03-31 Fermion Oy Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny
EP1928883B1 (de) * 2005-02-08 2013-10-30 Fermion Oy Verfahren zur herstellung von irinotecanhydrochlorid

Also Published As

Publication number Publication date
ES2343204T3 (es) 2010-07-26
EP2082741A1 (de) 2009-07-29
KR101150504B1 (ko) 2012-07-09
US20070072890A1 (en) 2007-03-29
WO2007035709A2 (en) 2007-03-29
EP1951235A4 (de) 2008-10-29
JP2009508874A (ja) 2009-03-05
CN101277694B (zh) 2011-04-20
KR20080059244A (ko) 2008-06-26
US7435818B2 (en) 2008-10-14
JP5119153B2 (ja) 2013-01-16
BRPI0616308A2 (pt) 2011-06-14
EP1951235A2 (de) 2008-08-06
AR056082A1 (es) 2007-09-19
DE602006012871D1 (de) 2010-04-22
CN101277694A (zh) 2008-10-01
NZ566807A (en) 2011-05-27
AU2006292328B2 (en) 2012-12-20
AU2006292328A1 (en) 2007-03-29
CA2623117A1 (en) 2007-03-29
CA2623117C (en) 2013-12-10
EP1951235B1 (de) 2010-03-10
WO2007035709A3 (en) 2007-10-25

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