ATE323511T1 - Technetium-99m markierte peptide zur bildformung - Google Patents

Technetium-99m markierte peptide zur bildformung

Info

Publication number
ATE323511T1
ATE323511T1 AT95922946T AT95922946T ATE323511T1 AT E323511 T1 ATE323511 T1 AT E323511T1 AT 95922946 T AT95922946 T AT 95922946T AT 95922946 T AT95922946 T AT 95922946T AT E323511 T1 ATE323511 T1 AT E323511T1
Authority
AT
Austria
Prior art keywords
peptides
technetium
methods
labeled peptides
image shaping
Prior art date
Application number
AT95922946T
Other languages
English (en)
Inventor
Richard T Dean
Scott Buttram
William Mcbride
John Lister-James
Edgar R Civitello
Original Assignee
Berlex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berlex Inc filed Critical Berlex Inc
Application granted granted Critical
Publication of ATE323511T1 publication Critical patent/ATE323511T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT95922946T 1994-06-03 1995-06-01 Technetium-99m markierte peptide zur bildformung ATE323511T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/253,678 US5997844A (en) 1991-02-08 1994-06-03 Technetium-99m labeled peptides for imaging

Publications (1)

Publication Number Publication Date
ATE323511T1 true ATE323511T1 (de) 2006-05-15

Family

ID=22961259

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95922946T ATE323511T1 (de) 1994-06-03 1995-06-01 Technetium-99m markierte peptide zur bildformung

Country Status (14)

Country Link
US (2) US5997844A (de)
EP (1) EP0762901B9 (de)
JP (1) JPH10501241A (de)
KR (1) KR100235136B1 (de)
CN (1) CN1090973C (de)
AT (1) ATE323511T1 (de)
AU (1) AU697048B2 (de)
CA (1) CA2191950C (de)
DE (1) DE69534943T2 (de)
DK (1) DK0762901T3 (de)
ES (1) ES2263153T3 (de)
PT (1) PT762901E (de)
WO (1) WO1995033498A1 (de)
ZA (1) ZA954547B (de)

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US5736122A (en) * 1991-02-08 1998-04-07 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
US5645815A (en) 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
US5989519A (en) * 1992-03-13 1999-11-23 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
JPH07504902A (ja) * 1992-03-13 1995-06-01 ダイアタイド・インコーポレイテッド 炎症造影用のテクネチウム−９９ｍ標識ペプチド
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
US5968476A (en) * 1992-05-21 1999-10-19 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
JP2005514335A (ja) * 2001-10-19 2005-05-19 トマス ジェファソン ユニバーシティ 腫瘍イメージング及び治療のためのｐａｃａｐ組成物及び方法
US7122189B2 (en) 2002-08-13 2006-10-17 Enzon, Inc. Releasable polymeric conjugates based on aliphatic biodegradable linkers
US8185176B2 (en) * 2005-04-26 2012-05-22 Novadaq Technologies, Inc. Method and apparatus for vasculature visualization with applications in neurosurgery and neurology
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WO2006114324A1 (en) * 2005-04-28 2006-11-02 Schering Ag Compounds comprising cyclized somatostatin receptor binding peptides
US20070122344A1 (en) 2005-09-02 2007-05-31 University Of Rochester Medical Center Office Of Technology Transfer Intraoperative determination of nerve location
AT502987A1 (de) * 2005-12-23 2007-07-15 Fibrex Medical Res & Dev Gmbh Pharmazeutische zusammensetzung zur behandlung von hämorrhagischem schock und seinen folgeerscheinungen
US20080161744A1 (en) 2006-09-07 2008-07-03 University Of Rochester Medical Center Pre-And Intra-Operative Localization of Penile Sentinel Nodes
TW200922624A (en) * 2007-07-11 2009-06-01 Enzon Pharmaceuticals Inc Polymeric drug delivery system containing a multi-substituted aromatic moiety
US8406860B2 (en) 2008-01-25 2013-03-26 Novadaq Technologies Inc. Method for evaluating blush in myocardial tissue
US10219742B2 (en) 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
ES2671710T3 (es) 2008-05-02 2018-06-08 Novadaq Technologies ULC Métodos para la producción y uso de eritrocitos cargados con sustancias para la observación y el tratamiento de la hemodinámica microvascular
EP2300032A4 (de) 2008-05-13 2012-12-05 Univ Kansas Metall-abstraktionspeptid (map)-tag und relevante verfahren
US10492671B2 (en) 2009-05-08 2019-12-03 Novadaq Technologies ULC Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest
US9187735B2 (en) 2012-06-01 2015-11-17 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
CA2914778A1 (en) 2012-06-21 2013-12-27 Novadaq Technologies Inc. Quantification and analysis of angiography and perfusion
DE102013113156A1 (de) 2013-11-28 2015-05-28 Freie Universität Berlin Verbindung und Verfahren zur selektiven Radiomarkierung von Polypeptiden mittels Festphasensynthese
CA2963987A1 (en) 2014-09-29 2016-04-07 Novadaq Technologies Inc. Imaging a target fluorophore in a biological material in the presence of autofluorescence
CN107427247B (zh) 2014-10-09 2021-06-04 史赛克欧洲运营有限公司 使用荧光介导的光电容积描记法的组织中的绝对血液流动的定量
CA3049922A1 (en) 2017-02-10 2018-08-16 Novadaq Technologies ULC Open-field handheld fluorescence imaging systems and methods

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US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
JPH07504902A (ja) * 1992-03-13 1995-06-01 ダイアタイド・インコーポレイテッド 炎症造影用のテクネチウム−９９ｍ標識ペプチド
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DK0641222T3 (da) * 1992-05-21 2000-12-11 Diatide Inc Peptider mærket med technetium-99m til trombeafbildning
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Also Published As

Publication number Publication date
EP0762901B9 (de) 2007-01-17
EP0762901A1 (de) 1997-03-19
US5997844A (en) 1999-12-07
AU2778395A (en) 1996-01-04
DE69534943D1 (de) 2006-05-24
CN1154072A (zh) 1997-07-09
CA2191950A1 (en) 1995-12-14
CA2191950C (en) 2003-01-28
ZA954547B (en) 1996-01-24
AU697048B2 (en) 1998-09-24
PT762901E (pt) 2006-08-31
CN1090973C (zh) 2002-09-18
WO1995033498A1 (en) 1995-12-14
EP0762901B1 (de) 2006-04-19
DE69534943T2 (de) 2007-03-08
ES2263153T3 (es) 2006-12-01
KR100235136B1 (ko) 1999-12-15
DK0762901T3 (da) 2006-08-21
JPH10501241A (ja) 1998-02-03
KR970703171A (ko) 1997-07-03
US6074627A (en) 2000-06-13

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