ATE238417T1 - Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung - Google Patents
Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendungInfo
- Publication number
- ATE238417T1 ATE238417T1 AT92924237T AT92924237T ATE238417T1 AT E238417 T1 ATE238417 T1 AT E238417T1 AT 92924237 T AT92924237 T AT 92924237T AT 92924237 T AT92924237 T AT 92924237T AT E238417 T1 ATE238417 T1 AT E238417T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- bone morphogenetic
- morphogenetic protein
- recombinant bone
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78749691A | 1991-11-04 | 1991-11-04 | |
US86469292A | 1992-04-07 | 1992-04-07 | |
PCT/US1992/009430 WO1993009229A1 (en) | 1991-11-04 | 1992-11-02 | Recombinant bone morphogenetic protein heterodimers, compositions and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE238417T1 true ATE238417T1 (de) | 2003-05-15 |
Family
ID=27120657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92924237T ATE238417T1 (de) | 1991-11-04 | 1992-11-02 | Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung |
Country Status (9)
Country | Link |
---|---|
US (5) | US5866364A (de) |
EP (1) | EP0612348B1 (de) |
JP (2) | JP3504263B2 (de) |
KR (1) | KR100259827B1 (de) |
AT (1) | ATE238417T1 (de) |
AU (1) | AU674500B2 (de) |
DE (1) | DE69233022T2 (de) |
MX (1) | MX9206315A (de) |
WO (1) | WO1993009229A1 (de) |
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US20080070842A1 (en) * | 1991-11-04 | 2008-03-20 | David Israel | Recombinant bone morphogenetic protein heterodimers, compositions and methods of use |
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AU7605394A (en) * | 1993-09-03 | 1995-03-22 | Regents Of The University Of California, The | Neural tissue affecting factor and compositions |
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US5679783A (en) * | 1994-11-22 | 1997-10-21 | The Regents Of The University Of California | DNA encoding a tissue differentiation affecting factor |
DE69636728D1 (de) | 1995-04-19 | 2007-01-04 | Bioph Biotech Entw Pharm Gmbh | Neues protein und verfahren zu dessen herstellung |
US6638912B2 (en) | 1995-05-01 | 2003-10-28 | The Regents Of The University Of California | Peptide compositions mimicking TGF-β activity |
US5780436A (en) * | 1995-05-01 | 1998-07-14 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
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US5674292A (en) | 1995-06-07 | 1997-10-07 | Stryker Corporation | Terminally sterilized osteogenic devices and preparation thereof |
EP0873424B1 (de) * | 1996-01-10 | 2004-08-25 | The University Of Liverpool | Metastasen induzierende dna's |
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- 1992-11-02 KR KR1019940701433A patent/KR100259827B1/ko not_active IP Right Cessation
- 1992-11-02 WO PCT/US1992/009430 patent/WO1993009229A1/en active IP Right Grant
- 1992-11-02 JP JP50867593A patent/JP3504263B2/ja not_active Expired - Fee Related
- 1992-11-02 DE DE69233022T patent/DE69233022T2/de not_active Expired - Lifetime
- 1992-11-02 EP EP92924237A patent/EP0612348B1/de not_active Expired - Lifetime
- 1992-11-02 AU AU30622/92A patent/AU674500B2/en not_active Expired
- 1992-11-03 MX MX9206315A patent/MX9206315A/es unknown
- 1992-11-27 US US07/989,847 patent/US5866364A/en not_active Expired - Lifetime
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1995
- 1995-06-06 US US08/469,411 patent/US6190880B1/en not_active Expired - Fee Related
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2001
- 2001-02-09 US US09/780,601 patent/US6593109B1/en not_active Expired - Fee Related
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2002
- 2002-07-22 JP JP2002212805A patent/JP2003125789A/ja active Pending
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2003
- 2003-02-28 US US10/375,150 patent/US7678885B2/en not_active Expired - Fee Related
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2007
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DE69233022T2 (de) | 2004-02-12 |
DE69233022D1 (de) | 2003-05-28 |
US6593109B1 (en) | 2003-07-15 |
MX9206315A (es) | 1993-05-01 |
WO1993009229A1 (en) | 1993-05-13 |
US5866364A (en) | 1999-02-02 |
JP2003125789A (ja) | 2003-05-07 |
EP0612348A1 (de) | 1994-08-31 |
US20090105137A1 (en) | 2009-04-23 |
US6190880B1 (en) | 2001-02-20 |
AU674500B2 (en) | 1997-01-02 |
US7678885B2 (en) | 2010-03-16 |
EP0612348B1 (de) | 2003-04-23 |
JPH07500968A (ja) | 1995-02-02 |
KR940703914A (ko) | 1994-12-12 |
KR100259827B1 (ko) | 2000-06-15 |
JP3504263B2 (ja) | 2004-03-08 |
AU3062292A (en) | 1993-06-07 |
US20030235888A1 (en) | 2003-12-25 |
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