ATA904099A - Verfahren zur herstellung von citalopram - Google Patents
Verfahren zur herstellung von citalopramInfo
- Publication number
- ATA904099A ATA904099A AT0904099A AT904099A ATA904099A AT A904099 A ATA904099 A AT A904099A AT 0904099 A AT0904099 A AT 0904099A AT 904099 A AT904099 A AT 904099A AT A904099 A ATA904099 A AT A904099A
- Authority
- AT
- Austria
- Prior art keywords
- producing citalopram
- citalopram
- producing
- Prior art date
Links
- WSEQXVZVJXJVFP-UHFFFAOYSA-N 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile Chemical compound O1CC2=CC(C#N)=CC=C2C1(CCCN(C)C)C1=CC=C(F)C=C1 WSEQXVZVJXJVFP-UHFFFAOYSA-N 0.000 title 1
- 229960001653 citalopram Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2282—Unsaturated compounds used as ligands
- B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
- B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
- B01J2231/42—Catalytic cross-coupling, i.e. connection of previously not connected C-atoms or C- and X-atoms without rearrangement
- B01J2231/4205—C-C cross-coupling, e.g. metal catalyzed or Friedel-Crafts type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/84—Metals of the iron group
- B01J2531/847—Nickel
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Materials Engineering (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA199900921 | 1999-06-25 | ||
PCT/DK1999/000643 WO2000011926A2 (en) | 1999-06-25 | 1999-11-19 | Method for the preparation of citalopram |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA904099A true ATA904099A (de) | 2002-05-15 |
AT409960B AT409960B (de) | 2002-12-27 |
Family
ID=8099044
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99968206T ATE213237T1 (de) | 1999-06-25 | 1999-11-19 | Verfahren zur herstellung von citalopram |
AT0904099A AT409960B (de) | 1999-06-25 | 1999-11-19 | Verfahren zur herstellung von citalopram |
AT0018501U AT4366U1 (de) | 1999-06-25 | 2001-03-13 | Verfahren zur herstellung von citalopram |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99968206T ATE213237T1 (de) | 1999-06-25 | 1999-11-19 | Verfahren zur herstellung von citalopram |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0018501U AT4366U1 (de) | 1999-06-25 | 2001-03-13 | Verfahren zur herstellung von citalopram |
Country Status (36)
Country | Link |
---|---|
US (1) | US6750358B2 (de) |
EP (1) | EP1105382B1 (de) |
JP (1) | JP3389571B2 (de) |
KR (1) | KR100491369B1 (de) |
CN (1) | CN1129593C (de) |
AR (1) | AR020573A1 (de) |
AT (3) | ATE213237T1 (de) |
AU (2) | AU1374800A (de) |
BG (1) | BG106190A (de) |
BR (1) | BR9917367A (de) |
CA (1) | CA2290125C (de) |
CH (1) | CH691304A5 (de) |
CZ (1) | CZ292174B6 (de) |
DE (2) | DE69900891D1 (de) |
DK (1) | DK1105382T3 (de) |
EA (1) | EA002661B1 (de) |
ES (1) | ES2172356T3 (de) |
FI (1) | FI108538B (de) |
GB (1) | GB2354240B (de) |
HK (1) | HK1047745B (de) |
HU (1) | HUP0103417A3 (de) |
IL (1) | IL145960A0 (de) |
IS (1) | IS5862A (de) |
IT (1) | ITMI991579A1 (de) |
MX (1) | MXPA01010986A (de) |
NO (1) | NO20010318L (de) |
NZ (1) | NZ514982A (de) |
PL (1) | PL345971A1 (de) |
PT (1) | PT1105382E (de) |
SE (1) | SE516689C2 (de) |
SI (1) | SI1105382T1 (de) |
SK (1) | SK18412001A3 (de) |
TR (1) | TR200103700T2 (de) |
UA (1) | UA62023C2 (de) |
WO (1) | WO2000011926A2 (de) |
ZA (1) | ZA200108855B (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI1140886T1 (en) | 1998-12-23 | 2003-08-31 | H. Lundbeck A/S | Method for the preparation of 5-cyanophthalide |
AR022329A1 (es) | 1999-01-29 | 2002-09-04 | Lundbeck & Co As H | Metodo para la preparacion de 5-cianoftalida |
ATE237604T1 (de) | 1999-04-14 | 2003-05-15 | Lundbeck & Co As H | Verfahren zur herstellung von citalopram |
ITMI991579A1 (it) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
ITMI991581A1 (it) * | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
DE19983836C1 (de) | 1999-10-25 | 2003-10-23 | Lundbeck As Valby H | Verfahren zur Herstellung von Citalopram, 4-[1-(4- Fluorphenyl)-methanoyl]-benzonitril-Derivate und Verfahren zu deren Herstellung und deren Verwendung |
EP1228056B1 (de) | 1999-10-25 | 2004-09-22 | H. Lundbeck A/S | Verfahren zur herstellung von citalopram |
AR026063A1 (es) | 1999-11-01 | 2002-12-26 | Lundbeck & Co As H | Metodo para la preparacion de 5-carboxiftalida. |
EA004742B1 (ru) | 1999-12-28 | 2004-08-26 | Х.Лундбекк А/С | Способ получения циталопрама |
JP2003519218A (ja) | 1999-12-30 | 2003-06-17 | ハー・ルンドベック・アクチエゼルスカベット | シタロプラムの製造方法 |
SI1254129T1 (en) | 2000-01-14 | 2004-02-29 | H. Lundbeck A/S | Method for the preparation of 5-cyanophthalide |
NL1017415C1 (nl) | 2000-02-24 | 2001-05-18 | Lundbeck & Co As H | Werkwijze voor de bereiding van Citalopram. |
NL1017417C1 (nl) | 2000-03-03 | 2001-03-16 | Lundbeck & Co As H | Werkwijze voor de bereiding van Citalopram. |
GB0005477D0 (en) | 2000-03-07 | 2000-04-26 | Resolution Chemicals Limited | Process for the preparation of citalopram |
CN1429219A (zh) | 2000-03-13 | 2003-07-09 | H·隆德贝克有限公司 | 制备西酞普兰的方法 |
NZ521204A (en) | 2000-03-13 | 2004-03-26 | H | Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)- 1,3-dihydroisobenzofurans for preparing citalopram, an anti depressant |
GB2357762B (en) * | 2000-03-13 | 2002-01-30 | Lundbeck & Co As H | Crystalline base of citalopram |
NL1017500C1 (nl) | 2000-03-13 | 2001-04-26 | Lundbeck & Co As H | Werkwijze voor de bereiding van Citalopram. |
WO2001068630A1 (en) | 2000-03-14 | 2001-09-20 | H. Lundbeck A/S | Method for the preparation of citalopram |
TR200202168T2 (tr) * | 2000-03-16 | 2002-12-23 | H. Lundbeck A/S | 5-Siyano-1-(4-Florofenil)-1,3-Dihidroizobenzofuranların preparasyon metodu |
AR032455A1 (es) | 2000-05-12 | 2003-11-12 | Lundbeck & Co As H | Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva |
BR0106976A (pt) * | 2000-07-06 | 2002-07-23 | Lundbeck & Co As H | Método para a preparação de citalopram |
IL144816A (en) * | 2000-08-18 | 2005-09-25 | Lundbeck & Co As H | Method for the preparation of citalopram |
SG167655A1 (en) * | 2000-12-22 | 2011-01-28 | Lundbeck & Co As H | Method for the preparation of pure citalopram |
JP2003519121A (ja) | 2000-12-28 | 2003-06-17 | ハー・ルンドベック・アクチエゼルスカベット | 純粋なシタロプラムの製造方法 |
CA2435925A1 (en) | 2001-01-30 | 2002-08-08 | Orion Corporation Fermion | Process for the preparation of 1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile |
WO2002072565A1 (en) * | 2001-03-09 | 2002-09-19 | Ranbaxy Laboratories Limited | Process for the preparation of citalopram |
MEP2108A (xx) | 2001-07-31 | 2010-02-10 | Lundbeck & Co As H | Kristalni sastav koji sadrži escitalopram |
WO2003057132A2 (en) | 2002-01-07 | 2003-07-17 | Sun Pharmaceutical Industries Limited | Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile |
AR040970A1 (es) | 2002-08-12 | 2005-04-27 | Lundbeck & Co As H | Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram |
TR200504022T1 (tr) * | 2003-03-24 | 2006-08-21 | Hetero Drugs Limited | (S)-sitalopram oksalatın yeni sıvı kristal formları. |
US7019153B2 (en) | 2003-06-10 | 2006-03-28 | Sun Pharmaceutical Industries Limited | Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid |
TWI339651B (en) | 2004-02-12 | 2011-04-01 | Lundbeck & Co As H | Method for the separation of intermediates which may be used for the preparation of escitalopram |
JP2006008603A (ja) * | 2004-06-25 | 2006-01-12 | Sumitomo Chemical Co Ltd | 光学活性シタロプラムの製造方法、その中間体およびその製造方法 |
EP2141156A1 (de) | 2004-08-23 | 2010-01-06 | Sun Pharma Global FZE | Verfahren zur Herstellung von Citalopram und Enantiomeren |
WO2006103550A1 (en) * | 2005-03-31 | 2006-10-05 | Ranbaxy Laboratories Limited | Processes for the preparation of citalopram and its intermediate 5-aminophthalide |
TWI358407B (en) | 2005-06-22 | 2012-02-21 | Lundbeck & Co As H | Crystalline base of escitalopram and orodispersibl |
US7834201B2 (en) | 2005-06-22 | 2010-11-16 | H. Lundbeck A/S | Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base |
EP2017271A1 (de) | 2007-07-06 | 2009-01-21 | Aurobindo Pharma Limited | Verfahren zur Herstellung von Escitalopram |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1143702A (de) | 1965-03-18 | |||
GB1526331A (en) * | 1976-01-14 | 1978-09-27 | Kefalas As | Phthalanes |
GB8419963D0 (en) | 1984-08-06 | 1984-09-12 | Lundbeck & Co As H | Intermediate compound and method |
GB8814057D0 (en) | 1988-06-14 | 1988-07-20 | Lundbeck & Co As H | New enantiomers & their isolation |
CA2010159A1 (en) | 1989-02-21 | 1990-08-21 | James J. Maul | Cyanation of haloaromatics utilizing catalysts generated in situ starting with nic1 or nic1 6h 0 |
US5296507A (en) | 1990-09-06 | 1994-03-22 | H.Lundbeck A/S | Treatment of cerbrovascular disorders |
DE19626659A1 (de) | 1996-07-03 | 1998-01-08 | Basf Ag | Verfahren zur Herstellung von Phthaliden |
DE19627697A1 (de) | 1996-07-10 | 1998-01-15 | Basf Ag | Verfahren zur Herstellung von Phthaliden |
DE19706648A1 (de) | 1997-02-20 | 1998-08-27 | Bayer Ag | Verfahren zur Herstellung von aromatischen Nitrilen |
ES2148120T3 (es) | 1997-07-08 | 2002-01-16 | Lundbeck & Co As H | Metodo para la preparacion de citalopram. |
UA62985C2 (en) | 1997-11-10 | 2004-01-15 | Lunnbeck As H | A method for the preparation of citalopram |
ES2149734T3 (es) | 1997-11-11 | 2003-02-16 | Lundbeck & Co As H | Metodo para la preparacion de citalopram. |
CN1129592C (zh) | 1998-10-20 | 2003-12-03 | H·隆德贝克有限公司 | 制备西酞普兰的方法 |
SI1140886T1 (en) | 1998-12-23 | 2003-08-31 | H. Lundbeck A/S | Method for the preparation of 5-cyanophthalide |
AR022329A1 (es) | 1999-01-29 | 2002-09-04 | Lundbeck & Co As H | Metodo para la preparacion de 5-cianoftalida |
DE10015280A1 (de) | 1999-03-29 | 2001-01-04 | Nissan Chemical Ind Ltd | Verfahren zur Herstellung von Benzonitrilverbindungen |
ATE237604T1 (de) | 1999-04-14 | 2003-05-15 | Lundbeck & Co As H | Verfahren zur herstellung von citalopram |
ITMI991579A1 (it) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
ITMI991581A1 (it) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
EP1228056B1 (de) | 1999-10-25 | 2004-09-22 | H. Lundbeck A/S | Verfahren zur herstellung von citalopram |
US6310222B1 (en) | 1999-11-01 | 2001-10-30 | Sumika Fine Chemicals Co., Ltd. | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate |
GB0005477D0 (en) | 2000-03-07 | 2000-04-26 | Resolution Chemicals Limited | Process for the preparation of citalopram |
SG167655A1 (en) | 2000-12-22 | 2011-01-28 | Lundbeck & Co As H | Method for the preparation of pure citalopram |
JP2003519121A (ja) | 2000-12-28 | 2003-06-17 | ハー・ルンドベック・アクチエゼルスカベット | 純粋なシタロプラムの製造方法 |
-
1999
- 1999-07-15 IT IT1999MI001579A patent/ITMI991579A1/it unknown
- 1999-11-19 KR KR10-2001-7013971A patent/KR100491369B1/ko not_active IP Right Cessation
- 1999-11-19 ES ES99968206T patent/ES2172356T3/es not_active Expired - Lifetime
- 1999-11-19 SK SK1841-2001A patent/SK18412001A3/sk unknown
- 1999-11-19 WO PCT/DK1999/000643 patent/WO2000011926A2/en active IP Right Grant
- 1999-11-19 PT PT99968206T patent/PT1105382E/pt unknown
- 1999-11-19 SI SI9930039T patent/SI1105382T1/xx unknown
- 1999-11-19 TR TR2001/03700T patent/TR200103700T2/xx unknown
- 1999-11-19 CH CH00307/01A patent/CH691304A5/de not_active IP Right Cessation
- 1999-11-19 CZ CZ2001319A patent/CZ292174B6/cs not_active IP Right Cessation
- 1999-11-19 EP EP99968206A patent/EP1105382B1/de not_active Expired - Lifetime
- 1999-11-19 CN CN99816768A patent/CN1129593C/zh not_active Expired - Fee Related
- 1999-11-19 IL IL14596099A patent/IL145960A0/xx unknown
- 1999-11-19 GB GB0101508A patent/GB2354240B/en not_active Expired - Fee Related
- 1999-11-19 HU HU0103417A patent/HUP0103417A3/hu unknown
- 1999-11-19 NZ NZ514982A patent/NZ514982A/xx unknown
- 1999-11-19 EA EA200101071A patent/EA002661B1/ru not_active IP Right Cessation
- 1999-11-19 BR BR9917367-0A patent/BR9917367A/pt not_active IP Right Cessation
- 1999-11-19 AU AU13748/00A patent/AU1374800A/en active Pending
- 1999-11-19 MX MXPA01010986A patent/MXPA01010986A/es not_active IP Right Cessation
- 1999-11-19 PL PL99345971A patent/PL345971A1/xx not_active Application Discontinuation
- 1999-11-19 AT AT99968206T patent/ATE213237T1/de not_active IP Right Cessation
- 1999-11-19 JP JP2000567065A patent/JP3389571B2/ja not_active Expired - Fee Related
- 1999-11-19 DE DE69900891T patent/DE69900891D1/de not_active Expired - Lifetime
- 1999-11-19 DK DK99968206T patent/DK1105382T3/da active
- 1999-11-19 AU AU2001100433A patent/AU2001100433B4/en not_active Ceased
- 1999-11-19 DE DE19983486T patent/DE19983486C2/de not_active Expired - Fee Related
- 1999-11-19 AT AT0904099A patent/AT409960B/de not_active IP Right Cessation
- 1999-11-19 UA UA2001117897A patent/UA62023C2/uk unknown
- 1999-11-22 CA CA002290125A patent/CA2290125C/en not_active Expired - Fee Related
-
2000
- 2000-06-21 AR ARP000103080A patent/AR020573A1/es unknown
-
2001
- 2001-01-19 NO NO20010318A patent/NO20010318L/no unknown
- 2001-01-24 SE SE0100194A patent/SE516689C2/sv not_active IP Right Cessation
- 2001-01-25 FI FI20010154A patent/FI108538B/fi not_active IP Right Cessation
- 2001-02-23 IS IS5862A patent/IS5862A/is unknown
- 2001-03-13 AT AT0018501U patent/AT4366U1/de not_active IP Right Cessation
- 2001-10-26 ZA ZA200108855A patent/ZA200108855B/xx unknown
- 2001-11-06 US US10/012,025 patent/US6750358B2/en not_active Expired - Fee Related
- 2001-12-07 BG BG106190A patent/BG106190A/xx unknown
-
2002
- 2002-12-24 HK HK02109330.8A patent/HK1047745B/zh not_active IP Right Cessation
Also Published As
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ATE237604T1 (de) | Verfahren zur herstellung von citalopram | |
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