AR245930A1 - Un nuevo procedimiento quimico para la sintesis de la n-metil-3,4-dimetoxifeniletilamina. - Google Patents

Un nuevo procedimiento quimico para la sintesis de la n-metil-3,4-dimetoxifeniletilamina.

Info

Publication number
AR245930A1
AR245930A1 AR90316461A AR31646190A AR245930A1 AR 245930 A1 AR245930 A1 AR 245930A1 AR 90316461 A AR90316461 A AR 90316461A AR 31646190 A AR31646190 A AR 31646190A AR 245930 A1 AR245930 A1 AR 245930A1
Authority
AR
Argentina
Prior art keywords
formula
methyl
alkaline
synthesis
dimetoxifeniletilamina
Prior art date
Application number
AR90316461A
Other languages
English (en)
Original Assignee
Alfa Chem Ital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Chem Ital filed Critical Alfa Chem Ital
Application granted granted Critical
Publication of AR245930A1 publication Critical patent/AR245930A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/50—Ethers of hydroxy amines of undetermined structure, e.g. obtained by reactions of epoxides with hydroxy amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO QUIMICO PARA LA SINTESIS DE LA N-METIL-3,4- DIMETOXIFENILETILAMINA DE FORMULA (I), QUE COMPRENDE: A) HACER REACCIONAR EL 3,4-DIMETOXIBENZALDEHIDO DE FORMULA (II), CON UN ALFA-HALOESTER DE FORMULA: X-CH2-COOR EN LA CUAL X ES HALOGENO Y R ES ALQUILO, EN PRESENCIA DE UN AGENTE ALCALINO COMO UN ALCOHOLATO DE UN METAL ALCALINO DE FORMULA: R1O(-) ME(+), R1 ES ALQUILO, AMIDA SODICA O HIDRURO DE SODIO, OPTATIVAMENTE EN PRESENCIA DE UN SOLVENTE COMO UN HIDROCARBURO AROMATICO Y UN ALCOHOL, O MEZCLAS DE LOS MISMOS; B) SOMETIENDO EL ESTER GLICIDICO RESULTANTE DE FORMULA (III),A UNA HIDROLISIS ALCALINA, PARA OBTENER UNA SAL ALCALINA DEL EPOXIACIDO DE FORMULA (IV); C) DESCARBOXILAR EL COMPUESTO DE FORMULA (IV), PARA OBTENER EL 3,4-DIMETOXIBENCENACETALDEHIDO DE FORMULA (V); D) TRATAR DICHO ALDEHIDO DE FORMULA (V) PRIMERO CON MONOMETILAMINA Y SUBSIGUIENTEMENTE CON BOROHIDRURO DE SODIO, PARA OBTENER LA N-METIL-3,4- DIMETOXIFENILETILAMINA DE FORMULA (I).
AR90316461A 1989-03-31 1990-03-27 Un nuevo procedimiento quimico para la sintesis de la n-metil-3,4-dimetoxifeniletilamina. AR245930A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8919959A IT1229214B (it) 1989-03-31 1989-03-31 Processo per la sintesi della n metil 3,4 dimetossifeniletilamina

Publications (1)

Publication Number Publication Date
AR245930A1 true AR245930A1 (es) 1994-03-30

Family

ID=11162654

Family Applications (1)

Application Number Title Priority Date Filing Date
AR90316461A AR245930A1 (es) 1989-03-31 1990-03-27 Un nuevo procedimiento quimico para la sintesis de la n-metil-3,4-dimetoxifeniletilamina.

Country Status (25)

Country Link
US (1) US5057624A (es)
EP (1) EP0389876B1 (es)
JP (1) JPH06102636B2 (es)
KR (1) KR940011899B1 (es)
AR (1) AR245930A1 (es)
AT (1) ATE92467T1 (es)
AU (1) AU627561B2 (es)
CA (1) CA2013080C (es)
DD (1) DD293109A5 (es)
DE (1) DE69002500T2 (es)
DK (1) DK0389876T3 (es)
ES (1) ES2058644T3 (es)
FI (1) FI102370B1 (es)
HR (1) HRP940599B1 (es)
HU (1) HU209947B (es)
IE (1) IE63954B1 (es)
IL (1) IL93762A (es)
IT (1) IT1229214B (es)
NO (1) NO170149C (es)
NZ (1) NZ232975A (es)
PL (1) PL162349B1 (es)
PT (1) PT93598B (es)
SI (1) SI9010634B (es)
YU (1) YU48167B (es)
ZA (1) ZA902003B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ345597A3 (cs) * 1995-05-17 1998-04-15 Basf Aktiengesellschaft Způsob přípravy N-methyl-2-(3,4-dimethoxyfenyl)ethylaminu
CN101580460B (zh) * 2009-05-26 2012-05-23 台州市知青化工有限公司 一种3，4-二羟基苯乙醇的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997608A (en) * 1973-07-05 1976-12-14 Richardson-Merrell Inc. N-substituted-dihydroxyphenethylamines
US3894051A (en) * 1973-07-05 1975-07-08 Colgate Palmolive Co N-methylenedioxyphenylalkyl)-{62 -(alkyl)-disubstituted phenethylamines
DE3338681A1 (de) * 1983-10-25 1985-05-09 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von n-methylhomoveratrylamin
GB8603765D0 (en) * 1986-02-15 1986-03-19 Beecham Wuelfung Gmbh & Co Kg Compounds
IT1215409B (it) * 1987-04-08 1990-02-08 Alfa Chem Ital Processo per la sintesi dell'alfa-(1-metiletil)-3,4-dimetossibenzeneacetonitrile.

Also Published As

Publication number Publication date
SI9010634B (sl) 1998-06-30
NO901454D0 (no) 1990-03-30
PT93598B (pt) 1996-03-29
DE69002500T2 (de) 1994-01-13
NZ232975A (en) 1991-11-26
HU902025D0 (en) 1990-07-28
IL93762A0 (en) 1990-12-23
EP0389876A1 (en) 1990-10-03
CA2013080A1 (en) 1990-09-30
NO170149C (no) 1992-09-16
ATE92467T1 (de) 1993-08-15
IL93762A (en) 1994-07-31
HRP940599B1 (en) 1998-04-30
JPH06102636B2 (ja) 1994-12-14
IT1229214B (it) 1991-07-25
FI102370B (fi) 1998-11-30
US5057624A (en) 1991-10-15
KR900014310A (ko) 1990-10-23
JPH02289539A (ja) 1990-11-29
ES2058644T3 (es) 1994-11-01
AU627561B2 (en) 1992-08-27
SI9010634A (en) 1997-08-31
HU209947B (en) 1994-12-28
NO901454L (no) 1990-10-01
IT8919959A0 (it) 1989-03-31
CA2013080C (en) 1997-07-22
AU5247090A (en) 1990-10-04
YU63490A (en) 1991-10-31
HRP940599A2 (en) 1997-06-30
YU48167B (sh) 1997-07-31
ZA902003B (en) 1990-12-28
DD293109A5 (de) 1991-08-22
NO170149B (no) 1992-06-09
KR940011899B1 (ko) 1994-12-27
PL162349B1 (pl) 1993-10-30
EP0389876B1 (en) 1993-08-04
FI102370B1 (fi) 1998-11-30
PT93598A (pt) 1990-11-20
DE69002500D1 (de) 1993-09-09
IE901171L (en) 1990-09-30
DK0389876T3 (da) 1993-09-27
IE63954B1 (en) 1995-06-28
HUT53865A (en) 1990-12-28
FI901611A0 (fi) 1990-03-30

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