AR001779A1 - Preparación terapéutica su uso dispositivo de inhalación de polvo seco y procedimientos de manufactura de dicha preparación - Google Patents
Preparación terapéutica su uso dispositivo de inhalación de polvo seco y procedimientos de manufactura de dicha preparaciónInfo
- Publication number
- AR001779A1 AR001779A1 AR33475995A AR33475995A AR001779A1 AR 001779 A1 AR001779 A1 AR 001779A1 AR 33475995 A AR33475995 A AR 33475995A AR 33475995 A AR33475995 A AR 33475995A AR 001779 A1 AR001779 A1 AR 001779A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- dry powder
- inhalation device
- manufacturing procedures
- powder inhalation
- Prior art date
Links
- 239000000843 powder Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 101001135770 Homo sapiens Parathyroid hormone Proteins 0.000 abstract 1
- 101001135995 Homo sapiens Probable peptidyl-tRNA hydrolase Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 102000003982 Parathyroid hormone Human genes 0.000 abstract 1
- 108090000445 Parathyroid hormone Proteins 0.000 abstract 1
- 102000058004 human PTH Human genes 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000199 parathyroid hormone Substances 0.000 abstract 1
- 229960001319 parathyroid hormone Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Una preparación terapéutica que contiene la hormona paratiroide útil para el tratamiento de la osteoporosis en mamíferos. Más particularmente, dichapreparación comprende una hormona paratiroide humana de longitud total u homólogos de lamism a en forma de un polvo seco que es apropiado parainhalación en el cual por lo menos el 50% de dicho polvo seco consiste en (a) partículas que tienen un diámetro de hasta 10 micrones; o b) aglomerados dedichas partículas. Además se dan aconocer pro cedimientos para la manufactura de dicha preparación, un dispositivo de inhalación y los usos de dichapreparación en dicho dispositivo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9404449A SE9404449D0 (sv) | 1994-12-22 | 1994-12-22 | Therapeutic preparations for inhalation |
SE9502576A SE9502576D0 (sv) | 1995-07-12 | 1995-07-12 | Therapeutic preparations for inhalation II |
Publications (1)
Publication Number | Publication Date |
---|---|
AR001779A1 true AR001779A1 (es) | 1997-12-10 |
Family
ID=26662192
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR33475995A AR001779A1 (es) | 1994-12-22 | 1995-12-21 | Preparación terapéutica su uso dispositivo de inhalación de polvo seco y procedimientos de manufactura de dicha preparación |
Country Status (27)
Country | Link |
---|---|
US (2) | US6436902B1 (es) |
EP (2) | EP0806945B1 (es) |
JP (1) | JPH10511090A (es) |
KR (1) | KR100389080B1 (es) |
CN (1) | CN1170527C (es) |
AR (1) | AR001779A1 (es) |
AT (1) | ATE238043T1 (es) |
AU (1) | AU703532B2 (es) |
BR (1) | BR9510516A (es) |
CA (1) | CA2206657C (es) |
CZ (1) | CZ182297A3 (es) |
DE (1) | DE69530519T2 (es) |
DK (1) | DK0806945T3 (es) |
EE (1) | EE9700136A (es) |
ES (1) | ES2197212T3 (es) |
FI (1) | FI972652A (es) |
HU (1) | HU218940B (es) |
IL (1) | IL116492A (es) |
IS (1) | IS4502A (es) |
MX (1) | MX9704544A (es) |
NO (1) | NO320432B1 (es) |
NZ (1) | NZ297921A (es) |
PL (1) | PL321094A1 (es) |
PT (1) | PT806945E (es) |
SK (1) | SK76797A3 (es) |
TR (1) | TR199501635A1 (es) |
WO (1) | WO1996019206A1 (es) |
Families Citing this family (30)
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US6794357B1 (en) | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
US6632456B1 (en) * | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
JP3901738B2 (ja) * | 1997-03-20 | 2007-04-04 | シェーリング コーポレイション | 粉末凝集体の調製 |
US6503537B2 (en) | 1997-03-20 | 2003-01-07 | Schering Corporation | Preparation of powder agglomerates |
US6495167B2 (en) | 1997-03-20 | 2002-12-17 | Schering Corporation | Preparation of powder agglomerates |
DZ2873A1 (fr) * | 1998-08-19 | 2003-12-15 | Lilly Co Eli | Procédé pour augmenter la dureté et la rigidité osseuse. |
WO2000023594A1 (en) | 1998-10-22 | 2000-04-27 | The General Hospital Corporation | BIOACTIVE PEPTIDES AND PEPTIDE DERIVATIVES OF PARATHYROID HORMONE (PTH) AND PARATHYROID HORMONE-RELATED PEPTIDE (PTHrP) |
WO2001077328A1 (en) * | 2000-04-06 | 2001-10-18 | Franco Wayne P | Methods of using growth factors for treating heart disease |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
KR20070010115A (ko) * | 2003-11-13 | 2007-01-22 | 알자 코포레이션 | 경피전달용 조성물 및 장치 |
US20070020298A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid |
US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
MX348041B (es) | 2003-12-31 | 2017-05-25 | Cydex Pharmaceuticals Inc | Formulación inhalante que contiene éter sulfoalquilico-ciclodextri na y un corticosteroide. |
JP2007522149A (ja) * | 2004-02-10 | 2007-08-09 | アドバンスト インハレーション リサーチ,インコーポレイテッド | 高速放出特性を有する吸入のための粒子 |
DE602004023765D1 (de) * | 2004-03-12 | 2009-12-03 | Trinity College Dublin | Magnetoresistives medium |
ES2717248T3 (es) | 2004-04-23 | 2019-06-20 | Cydex Pharmaceuticals Inc | Formulación de DPI que contiene sulfoalquil éter ciclodextrina |
US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
AU2006315132A1 (en) * | 2005-11-10 | 2007-05-24 | Board Of Control Of Michigan Technological University | Black bear parathyroid hormone and methods of using black bear parathyroid hormone |
US20070185066A1 (en) * | 2005-12-20 | 2007-08-09 | Verus Pharmaceuticals, Inc. | Systems and methods for the delivery of corticosteroids |
US20070178049A1 (en) * | 2005-12-20 | 2007-08-02 | Verus Pharmaceuticals, Inc. | Systems and methods for the delivery of corticosteroids having an enhanced pharmacokinetic profile |
US20070160542A1 (en) * | 2005-12-20 | 2007-07-12 | Verus Pharmaceuticals, Inc. | Methods and systems for the delivery of corticosteroids having an enhanced pharmacokinetic profile |
US20070197486A1 (en) * | 2005-12-20 | 2007-08-23 | Verus Pharmaceuticals, Inc. | Methods and systems for the delivery of corticosteroids |
US20070249572A1 (en) * | 2005-12-20 | 2007-10-25 | Verus Pharmaceuticals, Inc. | Systems and methods for the delivery of corticosteroids |
JP2009526858A (ja) * | 2006-02-15 | 2009-07-23 | ティカ レーケメデル アーベー | コルチコステロイド溶液を製造する方法 |
EP2187902B1 (en) | 2007-08-01 | 2013-04-17 | The General Hospital Corporation | Screening methods using g-protein coupled receptors and related compositions |
US8987201B2 (en) | 2009-12-07 | 2015-03-24 | Michigan Technological University | Black bear parathyroid hormone and methods of using black bear parathyroid hormone |
WO2011143406A2 (en) | 2010-05-13 | 2011-11-17 | The General Hospital Corporation | Parathyroid hormone analogs and uses thereof |
WO2012130193A1 (en) | 2011-03-31 | 2012-10-04 | Zentiva, K.S. | Non-covalent soluble complexes of teriparatide with polysaccharides and a dosage form of teriparatide for oral administration |
US10266228B2 (en) | 2016-06-24 | 2019-04-23 | Easy2.Company B.V. | Drive train for a treadle scooter |
EP4110370A4 (en) * | 2020-03-30 | 2023-06-07 | Sichuan Luzhou Buchang Bio-Pharmaceutical Co., Ltd. | FORMULATIONS OF HUMAN PARATHYROID HORMONE (PTH) AND METHODS OF MANUFACTURE THEREOF |
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-
1995
- 1995-12-08 SK SK767-97A patent/SK76797A3/sk unknown
- 1995-12-08 CN CNB951969544A patent/CN1170527C/zh not_active Expired - Fee Related
- 1995-12-08 ES ES95941953T patent/ES2197212T3/es not_active Expired - Lifetime
- 1995-12-08 HU HU9800553A patent/HU218940B/hu not_active IP Right Cessation
- 1995-12-08 PL PL95321094A patent/PL321094A1/xx unknown
- 1995-12-08 WO PCT/SE1995/001475 patent/WO1996019206A1/en active IP Right Grant
- 1995-12-08 BR BR9510516A patent/BR9510516A/pt not_active Application Discontinuation
- 1995-12-08 EP EP95941953A patent/EP0806945B1/en not_active Expired - Lifetime
- 1995-12-08 JP JP8519713A patent/JPH10511090A/ja active Pending
- 1995-12-08 CZ CZ971822A patent/CZ182297A3/cs unknown
- 1995-12-08 EE EE9700136A patent/EE9700136A/xx unknown
- 1995-12-08 KR KR1019970704255A patent/KR100389080B1/ko not_active IP Right Cessation
- 1995-12-08 PT PT95941953T patent/PT806945E/pt unknown
- 1995-12-08 MX MX9704544A patent/MX9704544A/es unknown
- 1995-12-08 DK DK95941953T patent/DK0806945T3/da active
- 1995-12-08 AU AU43199/96A patent/AU703532B2/en not_active Ceased
- 1995-12-08 CA CA002206657A patent/CA2206657C/en not_active Expired - Fee Related
- 1995-12-08 EP EP02025764A patent/EP1283035A3/en not_active Withdrawn
- 1995-12-08 AT AT95941953T patent/ATE238043T1/de active
- 1995-12-08 DE DE69530519T patent/DE69530519T2/de not_active Expired - Lifetime
- 1995-12-21 AR AR33475995A patent/AR001779A1/es unknown
- 1995-12-21 IL IL11649295A patent/IL116492A/xx not_active IP Right Cessation
- 1995-12-21 TR TR95/01635A patent/TR199501635A1/xx unknown
-
1997
- 1997-06-02 NZ NZ297921A patent/NZ297921A/en not_active IP Right Cessation
- 1997-06-09 IS IS4502A patent/IS4502A/is unknown
- 1997-06-12 NO NO19972715A patent/NO320432B1/no not_active IP Right Cessation
- 1997-06-19 FI FI972652A patent/FI972652A/fi unknown
-
1999
- 1999-08-26 US US09/383,590 patent/US6436902B1/en not_active Expired - Fee Related
-
2002
- 2002-08-19 US US10/224,522 patent/US20030064928A1/en not_active Abandoned
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