ES2154673T3 - Suministro intrapulmonar de hormonas. - Google Patents
Suministro intrapulmonar de hormonas.Info
- Publication number
- ES2154673T3 ES2154673T3 ES94908671T ES94908671T ES2154673T3 ES 2154673 T3 ES2154673 T3 ES 2154673T3 ES 94908671 T ES94908671 T ES 94908671T ES 94908671 T ES94908671 T ES 94908671T ES 2154673 T3 ES2154673 T3 ES 2154673T3
- Authority
- ES
- Spain
- Prior art keywords
- patient
- formulation
- intrapulmonary
- supply
- response
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/008—Electronic counters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0083—Timers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
Abstract
SE PROPORCIONA UN METODO PARA EL TRATAMIENTO DE PACIENTES HUMANOS MEDIANTE EL SUMINISTRO INTRAPULMONAR DE UNA FORMULACION HORMONAL FARMACOLOGICAMENTE ACTIVA (4). LA FORMULACION SE LIBERA DE FORMA AUTOMATICA DESDE UN MECANISMO, AUTONOMO, PORTATIL, FORMADO POR MEDIOS (7) PARA LIBERAR AUTOMATICAMENTE UNA CANTIDAD MEDIDA DE UN MEDICAMENTO EN EL CONDUCTO DEL FLUJO INSPIRATORIO DEL PACIENTE, EN RESPUESTA A LA INFORMACION OBTENIDA A PARTIR DE LOS MEDIOS (22) DE ANALISIS DEL FLUJO INSPIRATORIO DEL PACIENTE Y DESPUES DE QUE AL PACIENTE SE LE HAYA ENVIADO UNA SEÑAL AUDITIVA O VISUAL. SE OBTIENE UNA DOSIFICACION REPRODUCIBLE PROPORCIONANDO UNA LIBERACION AUTOMATICA EN RESPUESTA A UN PERFIL DE INHALACION MEDIDA. LA SOBREADMINISTRACION DE LA FORMULACION HORMONAL SE EVITA PROPORCIONANDO UN MICROPROCESADOR PREPROGRAMADO DISEÑADO PARA EVITAR LA SOBREDOSIFICACION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1098993A | 1993-01-29 | 1993-01-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2154673T3 true ES2154673T3 (es) | 2001-04-16 |
Family
ID=21748377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94908671T Expired - Lifetime ES2154673T3 (es) | 1993-01-29 | 1994-01-27 | Suministro intrapulmonar de hormonas. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5419315A (es) |
EP (1) | EP0681491B1 (es) |
JP (1) | JPH08509465A (es) |
AU (1) | AU6167894A (es) |
DE (1) | DE69426415T2 (es) |
ES (1) | ES2154673T3 (es) |
WO (1) | WO1994016756A1 (es) |
Families Citing this family (77)
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US6012450A (en) * | 1993-01-29 | 2000-01-11 | Aradigm Corporation | Intrapulmonary delivery of hematopoietic drug |
US6024090A (en) * | 1993-01-29 | 2000-02-15 | Aradigm Corporation | Method of treating a diabetic patient by aerosolized administration of insulin lispro |
US7448375B2 (en) * | 1993-01-29 | 2008-11-11 | Aradigm Corporation | Method of treating diabetes mellitus in a patient |
US5747445A (en) * | 1993-06-24 | 1998-05-05 | Astra Aktiebolag | Therapeutic preparation for inhalation |
US20010003739A1 (en) * | 1993-06-24 | 2001-06-14 | Astrazeneca Ab | Systemic administration of a therapeutic preparation |
TW402506B (en) | 1993-06-24 | 2000-08-21 | Astra Ab | Therapeutic preparation for inhalation |
US6632456B1 (en) | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
IS1796B (is) * | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
US5830853A (en) | 1994-06-23 | 1998-11-03 | Astra Aktiebolag | Systemic administration of a therapeutic preparation |
US6794357B1 (en) * | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
US20030113273A1 (en) * | 1996-06-17 | 2003-06-19 | Patton John S. | Methods and compositions for pulmonary delivery of insulin |
WO1995024183A1 (en) | 1994-03-07 | 1995-09-14 | Inhale Therapeutic Systems | Methods and compositions for pulmonary delivery of insulin |
US6165976A (en) | 1994-06-23 | 2000-12-26 | Astra Aktiebolag | Therapeutic preparation for inhalation |
US5635159A (en) * | 1994-08-26 | 1997-06-03 | Abbott Laboratories | Aerosol drug formulations containing polyglycolyzed glycerides |
PL321094A1 (en) | 1994-12-22 | 1997-11-24 | Astra Ab | Parathyroid hormone (pth) containing preparation administered by inhalation |
US6524557B1 (en) * | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
JP4155594B2 (ja) | 1994-12-22 | 2008-09-24 | アストラゼネカ・アクチエボラーグ | エアゾール製剤 |
US5758637A (en) | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US5809997A (en) * | 1995-05-18 | 1998-09-22 | Medtrac Technologies, Inc. | Electronic medication chronolog device |
US5635161A (en) * | 1995-06-07 | 1997-06-03 | Abbott Laboratories | Aerosol drug formulations containing vegetable oils |
WO2004096328A1 (ja) * | 1995-07-12 | 2004-11-11 | Hiroyuki Yokoi | ハンディ型吸入器 |
CA2392466C (en) | 1995-12-07 | 2004-05-04 | Jago Research Ag | Inhaler for multiple dosed administration of a pharmacological dry powder |
US7131441B1 (en) | 1995-12-07 | 2006-11-07 | Skyepharma Ag | Inhaler for multiple dosed administration of a pharmacological dry powder |
US5829435A (en) * | 1997-02-24 | 1998-11-03 | Aradigm Corporation | Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles |
US6197746B1 (en) | 1998-05-19 | 2001-03-06 | Repligen Corporation | Method of using secretin for treating autism |
DE69830185D1 (de) | 1997-05-19 | 2005-06-16 | Repligen Corp | Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromen |
NZ506289A (en) * | 1998-03-16 | 2004-12-24 | Nektar Therapeutics | Aerosolized active agent delivery to the lungs at a flow rate of less than 17 liters per minute |
US6260549B1 (en) | 1998-06-18 | 2001-07-17 | Clavius Devices, Inc. | Breath-activated metered-dose inhaler |
UA73924C2 (en) * | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
US6606992B1 (en) * | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
US6235177B1 (en) | 1999-09-09 | 2001-05-22 | Aerogen, Inc. | Method for the construction of an aperture plate for dispensing liquid droplets |
US6540983B1 (en) * | 2000-01-25 | 2003-04-01 | Aeropharm Technology Incorporated | Medical aerosol formulation |
EP1267718A2 (en) | 2000-04-03 | 2003-01-02 | IEP Pharmaceutical Devices, Inc. | Method for measuring changes in the airways of humans and other mammals |
US7971588B2 (en) | 2000-05-05 | 2011-07-05 | Novartis Ag | Methods and systems for operating an aerosol generator |
US8336545B2 (en) | 2000-05-05 | 2012-12-25 | Novartis Pharma Ag | Methods and systems for operating an aerosol generator |
US6543443B1 (en) * | 2000-07-12 | 2003-04-08 | Aerogen, Inc. | Methods and devices for nebulizing fluids |
US7677467B2 (en) | 2002-01-07 | 2010-03-16 | Novartis Pharma Ag | Methods and devices for aerosolizing medicament |
WO2003057291A1 (en) | 2002-01-07 | 2003-07-17 | Aerogen, Inc. | Devices and methods for nebulizing fluids for inhalation |
EP1474196B1 (en) | 2002-01-15 | 2016-08-17 | Novartis AG | Methods and systems for operating an aerosol generator |
WO2003088961A1 (en) * | 2002-04-19 | 2003-10-30 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disorders |
AU2003256253A1 (en) | 2002-05-20 | 2003-12-02 | Aerogen, Inc. | Aerosol for medical treatment and methods |
US7185651B2 (en) * | 2002-06-18 | 2007-03-06 | Nektar Therapeutics | Flow regulator for aerosol drug delivery and methods |
WO2004037843A2 (en) * | 2002-10-25 | 2004-05-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments |
US20040105818A1 (en) | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
US7638138B2 (en) * | 2003-02-21 | 2009-12-29 | Translational Research, Ltd. | Compositions for nasal administration of pharmaceuticals |
KR100974482B1 (ko) | 2003-03-27 | 2010-08-10 | 가부시키가이샤 바이오악티스 | 비강용 분말 약제 투약 장치 |
US8616195B2 (en) | 2003-07-18 | 2013-12-31 | Novartis Ag | Nebuliser for the production of aerosolized medication |
US7946291B2 (en) | 2004-04-20 | 2011-05-24 | Novartis Ag | Ventilation systems and methods employing aerosol generators |
CA2564083C (en) * | 2004-04-23 | 2014-02-04 | Philip Morris Usa Inc. | Aerosol generators and methods for producing aerosols |
WO2006016530A1 (ja) * | 2004-08-10 | 2006-02-16 | Translational Research, Ltd. | 速効性でかつ高い吸収性を可能とする経鼻投与用組成物 |
SG156680A1 (en) | 2004-10-27 | 2009-11-26 | Univ Florida | Adrenocorticotropic hormone analogs and related methods |
CN101208123B (zh) | 2005-05-25 | 2012-09-19 | 亚罗擎公司 | 振动***和方法 |
US8348853B2 (en) * | 2006-02-06 | 2013-01-08 | Deka Products Limited Partnership | System, method and device for aiding in the diagnosis of respiratory dysfunction |
ES2622493T3 (es) | 2006-02-24 | 2017-07-06 | Rigel Pharmaceuticals, Inc. | Composiciones y métodos para la inhibición de la ruta de JAK |
EP2037999B1 (en) | 2006-07-07 | 2016-12-28 | Proteus Digital Health, Inc. | Smart parenteral administration system |
US8337817B2 (en) | 2006-12-26 | 2012-12-25 | Shin Nippon Biomedical Laboratories, Ltd. | Preparation for transnasal application |
JP5243548B2 (ja) | 2007-10-25 | 2013-07-24 | プロテウス デジタル ヘルス, インコーポレイテッド | 情報システムのための流体伝達ポート |
PE20150621A1 (es) | 2009-01-23 | 2015-05-07 | Rigel Pharmaceuticals Inc | Derivados de 2,4-diamino-pirimidina n2, n4-disustituidos como inhibidores de jak3 |
US9101539B2 (en) * | 2009-05-15 | 2015-08-11 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal pharmaceutical compositions with improved pharmacokinetics |
GB2472327B (en) * | 2009-07-31 | 2013-03-13 | Shin Nippon Biomedical Lab Ltd | Intranasal granisetron and nasal applicator |
AU2011210352A1 (en) | 2010-01-26 | 2012-08-09 | Radikal Therapeutics Inc. | Compositions and methods for prevention and treatment of pulmonary hypertension |
SG189763A1 (en) | 2010-02-01 | 2013-05-31 | Proteus Digital Health Inc | Two-wrist data gathering system |
JP5841951B2 (ja) | 2010-02-01 | 2016-01-13 | プロテウス デジタル ヘルス, インコーポレイテッド | データ収集システム |
CA2865504A1 (en) | 2012-03-23 | 2013-09-26 | Oxigene, Inc. | Compositions and methods for inhibition of cathepsins |
US10987048B2 (en) * | 2014-08-13 | 2021-04-27 | Elwha Llc | Systems, methods, and devices to incentivize inhaler use |
US10765817B2 (en) | 2014-08-13 | 2020-09-08 | Elwha, Llc | Methods, systems, and devices related to delivery of alcohol with an inhaler |
DK3212212T3 (da) | 2014-10-31 | 2020-12-21 | Univ Monash | Pulverformulering |
CN111603643B (zh) | 2015-04-02 | 2023-05-23 | 希尔-罗姆服务私人有限公司 | 呼吸装置的压力控制 |
AU2016287372B2 (en) * | 2015-06-30 | 2021-07-01 | Koninklijke Philips N.V. | Control device for a medical aerosol delivery device |
CN108136144B (zh) | 2015-07-20 | 2020-10-30 | 珍珠治疗公司 | 气雾剂输送*** |
TWI664024B (zh) * | 2016-07-27 | 2019-07-01 | 和淞科技股份有限公司 | 噴霧裝置 |
US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
WO2020092845A1 (en) | 2018-11-01 | 2020-05-07 | Rigel Pharmaceuticals, Inc. | Method and composition embodiments for treating acute myeloid leukemia |
WO2020243612A1 (en) | 2019-05-29 | 2020-12-03 | Rigel Pharmaceuticals, Inc. | Method of preventing and treating thrombosis |
WO2021026451A1 (en) | 2019-08-08 | 2021-02-11 | Rigel Pharmaceuticals, Inc. | Compounds and method for treating cytokine release syndrome |
BR112022001896A2 (pt) | 2019-08-14 | 2022-06-21 | Rigel Pharmaceuticals Inc | Método para bloquear ou atenuar síndrome de liberação de citocinas |
TW202346291A (zh) | 2022-03-23 | 2023-12-01 | 美商雷傑製藥公司 | 作為irak抑制劑的嘧啶—2—基—吡唑化合物 |
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US4106503A (en) * | 1977-03-11 | 1978-08-15 | Richard R. Rosenthal | Metering system for stimulating bronchial spasm |
US4604847A (en) * | 1983-09-14 | 1986-08-12 | Moulding Jr Thomas S | Medicine package, method of opening the package, and machine for performing the method |
FI76929C (fi) * | 1984-09-25 | 1989-01-10 | Etelae Haemeen Keuhkovammayhdi | Inhalationsdoseringsanordning, som aer avsedd foer nogrann dosering av disponerande laekemedel som ges aot andningssjuka i undersoekningsskedet och/eller laekemedel som ges som spray under behandlingen. |
NZ209900A (en) * | 1984-10-16 | 1989-08-29 | Univ Auckland | Automatic inhaler |
US4686231A (en) * | 1985-12-12 | 1987-08-11 | Smithkline Beckman Corporation | Inhibition of 5-lipoxygenase products |
NZ219021A (en) * | 1986-01-27 | 1989-06-28 | Gea Farmaceutisk Fabrik As | Inhaler: medicine discharged intermittently during each inhalation |
DE3636669C2 (de) * | 1986-10-28 | 2001-08-16 | Siemens Ag | Anordnung zur Zufuhr von Aerosol zu den Luftwegen und/oder Lungen eines Patienten |
US4984158A (en) * | 1988-10-14 | 1991-01-08 | Hillsman Dean | Metered dose inhaler biofeedback training and evaluation system |
GB8900267D0 (en) * | 1989-01-06 | 1989-03-08 | Riker Laboratories Inc | Narcotic analgesic formulations and apparatus containing same |
SE466684B (sv) * | 1989-03-07 | 1992-03-23 | Draco Ab | Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator |
GB9023282D0 (en) * | 1990-10-25 | 1990-12-05 | Riker Laboratories Inc | Inhalation device |
GB9023281D0 (en) * | 1990-10-25 | 1990-12-05 | Riker Laboratories Inc | Inhaler |
US5404871A (en) * | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
WO1992017231A1 (en) * | 1991-03-28 | 1992-10-15 | Innomed, Inc. | Microelectronic inhaler having a counter and timer |
US5167506A (en) * | 1991-10-24 | 1992-12-01 | Minnesota Mining And Manufacturing Company | Inhalation device training system |
US5333106A (en) * | 1992-10-09 | 1994-07-26 | Circadian, Inc. | Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers |
-
1994
- 1994-01-27 JP JP6517378A patent/JPH08509465A/ja not_active Ceased
- 1994-01-27 AU AU61678/94A patent/AU6167894A/en not_active Abandoned
- 1994-01-27 ES ES94908671T patent/ES2154673T3/es not_active Expired - Lifetime
- 1994-01-27 DE DE69426415T patent/DE69426415T2/de not_active Expired - Fee Related
- 1994-01-27 EP EP94908671A patent/EP0681491B1/en not_active Expired - Lifetime
- 1994-01-27 WO PCT/US1994/001072 patent/WO1994016756A1/en active IP Right Grant
- 1994-07-25 US US08/279,720 patent/US5419315A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH08509465A (ja) | 1996-10-08 |
EP0681491A4 (en) | 1996-03-06 |
DE69426415T2 (de) | 2001-07-26 |
DE69426415D1 (en) | 2001-01-18 |
WO1994016756A1 (en) | 1994-08-04 |
AU6167894A (en) | 1994-08-15 |
EP0681491B1 (en) | 2000-12-13 |
US5419315A (en) | 1995-05-30 |
EP0681491A1 (en) | 1995-11-15 |
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FG2A | Definitive protection |
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