ZA995212B - The use of aryl-cyclohexylamine derivatives against CNS disorders. - Google Patents

The use of aryl-cyclohexylamine derivatives against CNS disorders.

Info

Publication number: ZA995212B
Authority: ZA; South Africa
Prior art keywords: aryl; cns disorders; derivatives against; against cns; cyclohexylamine derivatives
Prior art date: 1998-08-18

Application number

ZA9905212A

Other languages

English (en)

Inventor

Alexander Alanine

Bernd Buttelmann

Marie-Paule Heitz Neidhart

Emmanuel Pinard

Rene Wyler

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-18

Filing date

1999-08-16

Publication date

2000-02-18

1999-08-16 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2000-02-18 Publication of ZA995212B publication Critical patent/ZA995212B/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Emergency Medicine (AREA)
Psychology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

ZA9905212A 1998-08-18 1999-08-16 The use of aryl-cyclohexylamine derivatives against CNS disorders. ZA995212B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP98115484		1998-08-18

Publications (1)

Publication Number	Publication Date
ZA995212B true ZA995212B (en)	2000-02-18

Family

ID=8232474

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9905212A ZA995212B (en)	1998-08-18	1999-08-16	The use of aryl-cyclohexylamine derivatives against CNS disorders.

Country Status (24)

Country	Link
US (1)	US6184236B1 (xx)
JP (1)	JP3455142B2 (xx)
KR (1)	KR100341194B1 (xx)
CN (1)	CN1141936C (xx)
AR (1)	AR021770A1 (xx)
AT (1)	ATE326219T1 (xx)
AU (1)	AU756408B2 (xx)
BR (1)	BR9903779A (xx)
CA (1)	CA2280455A1 (xx)
DE (1)	DE69931316D1 (xx)
HR (1)	HRP990256A2 (xx)
HU (1)	HUP9902737A3 (xx)
ID (1)	ID23107A (xx)
IL (1)	IL131399A0 (xx)
MA (1)	MA26677A1 (xx)
MY (1)	MY133133A (xx)
NO (1)	NO993948L (xx)
NZ (1)	NZ337243A (xx)
PE (1)	PE20000955A1 (xx)
PL (1)	PL334949A1 (xx)
SG (1)	SG82014A1 (xx)
TR (1)	TR199902015A2 (xx)
YU (1)	YU38699A (xx)
ZA (1)	ZA995212B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1292581B1 (en) *	2000-06-06	2005-08-10	Warner-Lambert Company LLC	Bicyclic cyclohexylamines and their use as nmda receptor antagonists
EP1436258A4 (en) *	2001-03-08	2005-03-23	Univ Emory	ANTAGONISTS OF THE NMDA RECEPTOR DEPENDENT OF PH
DE10153345A1 (de) *	2001-10-29	2003-05-08	Gruenenthal Gmbh	Substituierte 1H-Chinoxalin-2-on-Verbindungen und substituierte 4-Aryl- und 4-Heteroarylcyclohexan-Verbindungen
US20070004805A1 (en) *	2005-07-01	2007-01-04	Navinta Llc	Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate
EP2170334B1 (en) *	2007-06-29	2021-03-17	Emory University	Nmda receptor antagonists for neuroprotection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4032766A1 (de)	1990-10-16	1992-04-30	Basf Ag	Phenylpiperidinoylamine und diese enthaltende arzneimittel
DE4117904A1 (de)	1991-05-31	1992-12-03	Basf Ag	Substituierte n-phenylpiperidine
EP0503411B1 (de)	1991-03-14	1995-11-29	BASF Aktiengesellschaft	Substituierte N-Phenylpiperidine und Arzneimittel daraus
AU715216B2 (en) *	1995-10-26	2000-01-20	Mitsubishi-Tokyo Pharmaceuticals, Inc.	Phenylethanolamine compounds useful as beta3 agonist, process for producing the same, and intermediates in the production of the same

1999
- 1999-08-09 DE DE69931316T patent/DE69931316D1/de not_active Expired - Lifetime
- 1999-08-09 US US09/370,602 patent/US6184236B1/en not_active Expired - Fee Related
- 1999-08-09 AT AT99115114T patent/ATE326219T1/de not_active IP Right Cessation
- 1999-08-13 PE PE1999000826A patent/PE20000955A1/es not_active Application Discontinuation
- 1999-08-13 NZ NZ337243A patent/NZ337243A/xx unknown
- 1999-08-13 IL IL13139999A patent/IL131399A0/xx unknown
- 1999-08-13 CA CA002280455A patent/CA2280455A1/en not_active Abandoned
- 1999-08-13 AR ARP990104079A patent/AR021770A1/es not_active Application Discontinuation
- 1999-08-16 SG SG9903973A patent/SG82014A1/en unknown
- 1999-08-16 MY MYPI99003508A patent/MY133133A/en unknown
- 1999-08-16 JP JP22965899A patent/JP3455142B2/ja not_active Expired - Fee Related
- 1999-08-16 ZA ZA9905212A patent/ZA995212B/xx unknown
- 1999-08-16 HU HU9902737A patent/HUP9902737A3/hu unknown
- 1999-08-16 YU YU38699A patent/YU38699A/sh unknown
- 1999-08-16 ID IDP990791A patent/ID23107A/id unknown
- 1999-08-17 MA MA25736A patent/MA26677A1/fr unknown
- 1999-08-17 PL PL99334949A patent/PL334949A1/xx not_active Application Discontinuation
- 1999-08-17 NO NO993948A patent/NO993948L/no unknown
- 1999-08-17 CN CNB991179110A patent/CN1141936C/zh not_active Expired - Fee Related
- 1999-08-17 KR KR1019990033814A patent/KR100341194B1/ko not_active IP Right Cessation
- 1999-08-17 BR BR9903779-3A patent/BR9903779A/pt not_active IP Right Cessation
- 1999-08-17 AU AU44537/99A patent/AU756408B2/en not_active Ceased
- 1999-08-18 TR TR1999/02015A patent/TR199902015A2/xx unknown
- 1999-08-18 HR HR98115484.2A patent/HRP990256A2/hr not_active Application Discontinuation

Also Published As

Publication number	Publication date
TR199902015A3 (tr)	2000-03-21
KR100341194B1 (ko)	2002-06-20
HU9902737D0 (en)	1999-10-28
JP2000109429A (ja)	2000-04-18
MA26677A1 (fr)	2004-12-20
ID23107A (id)	2000-02-24
AR021770A1 (es)	2002-08-07
NZ337243A (en)	2000-12-22
HUP9902737A2 (hu)	2000-06-28
NO993948D0 (no)	1999-08-17
ATE326219T1 (de)	2006-06-15
NO993948L (no)	2000-02-21
CA2280455A1 (en)	2000-02-18
PE20000955A1 (es)	2000-09-28
AU756408B2 (en)	2003-01-09
YU38699A (sh)	2002-03-18
HRP990256A2 (en)	2000-04-30
CN1141936C (zh)	2004-03-17
MY133133A (en)	2007-10-31
CN1248439A (zh)	2000-03-29
IL131399A0 (en)	2001-01-28
BR9903779A (pt)	2000-09-19
DE69931316D1 (de)	2006-06-22
TR199902015A2 (xx)	2000-03-21
HUP9902737A3 (en)	2001-01-29
SG82014A1 (en)	2001-07-24
US6184236B1 (en)	2001-02-06
PL334949A1 (en)	2000-02-28
AU4453799A (en)	2000-05-04
JP3455142B2 (ja)	2003-10-14
KR20000017343A (ko)	2000-03-25

Publication	Publication Date	Title
PL380733A1 (pl)	2006-11-13	Pochodne 3, 3-difenylopropyloamin, sposoby ich wytwarzania, ich zastosowanie medyczne oraz kompozycja farmaceutyczna
ZA99254B (en)	1999-07-16	Benzosulfone derivatives.
ZA200107689B (en)	2002-12-18	1-Arenesulfonyl-2-aryl-pyrrolidine and piperidine derivatives for the treatment of CNS disorders.
ZA9810218B (en)	1999-05-10	Isoquinoline derivatives for use against cns disorders
HK1039124A1 (en)	2002-04-12	Phthalzaine derivatives phosphodiesterase 4 inhibitors.
ZA992322B (en)	1999-09-20	Phosphodiesterase iv-inhibiting diazepinoindoles.
PL342060A1 (en)	2001-05-21	Derivatives of 1,3,4-oxadiaxolone
ZA991550B (en)	1999-08-26	Cyclohexanediole derivatives.
IL128749A0 (en)	2000-01-31	Cooking aid of the bar type
ZA995212B (en)	2000-02-18	The use of aryl-cyclohexylamine derivatives against CNS disorders.
MXPA03001472A (es)	2003-06-06	Compuestos para el tratamiento de trastornos adictivos.
ZA200110539B (en)	2003-03-24	Oxazinocarbazoles for the treatment of CNS diseases.
GB9801584D0 (en)	1998-03-25	The maitriser
HU9900123D0 (en)	1999-03-29	1-isothiazolidinone derivatives of azetidine-2-one, processes for the preparation thereof and use thereof
TW375224U (en)	1999-11-21	Improvement on the spout of easy type
GB9816352D0 (en)	1998-09-23	The treatment of inflammatory disorders
GB9816349D0 (en)	1998-09-23	The treatment of inflammatory disorders
GB9815356D0 (en)	1998-09-16	The miracle line
GB9809622D0 (en)	1998-07-01	The cereal bar
GB9807853D0 (en)	1998-06-10	The cardphone
TW355371U (en)	1999-04-01	The sprots spplies
GB9815214D0 (en)	1998-09-09	The multifan
GB9819730D0 (en)	1998-11-04	The waterhorse
GB9824699D0 (en)	1999-01-06	The profile line =#1
ZA200002584B (en)	2000-11-28	The monitoring of transformers.