YU38699A - Primena derivata aril-cikloheksilamina protiv poremećaja centralnog nervnog sistema - Google Patents
Primena derivata aril-cikloheksilamina protiv poremećaja centralnog nervnog sistemaInfo
- Publication number
- YU38699A YU38699A YU38699A YU38699A YU38699A YU 38699 A YU38699 A YU 38699A YU 38699 A YU38699 A YU 38699A YU 38699 A YU38699 A YU 38699A YU 38699 A YU38699 A YU 38699A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- lower alkyl
- cyclohexalamine
- aryl
- naphtil
- hydroxy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
Ovaj pronalazak se odnosi na primenu jedinjenja opste formule u kojoj oznacavaju Ar1 fenil, naftil ili tetrahidronaftil, koji je u datom slucaju supstituisan hidroksi-, nizom alkoksi-, nitro-, amino- ili metansulfonamido-grupom, Ar2 fenil, naftil ili tetrahidronaftil, koji je u datom slucaju supstituisan nizim alkilom ili halogenom, X C, CH, C(OH) ili N, Y -CH2-, CH ili O, Z -CH2-, -CH(CH3)- ili -CH(CH3)2-, R1 vodonik, nizi alkil ili acetil, A C=O ili -(CHR2)n-, pri cemu R2 oznacava vodonik, nizi alkil ili hidroksi-nizi alkil, B -(CH2)n-, O, -CH(OH) (CH2)n-, -CH(CH2OH) (CH2)n-, -(CH2)nCH(OH)- ili -CH(CH2OH)-, --- moze oznacavati vezu i n 0-4 i njihovih farmaceutski prihvatljivih kiselinskih adicionih soli za proizvodnju lekova koji reprezentuju terapijske indikacije za specificne blokere podtipa NMDA receptora.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98115484 | 1998-08-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU38699A true YU38699A (sh) | 2002-03-18 |
Family
ID=8232474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU38699A YU38699A (sh) | 1998-08-18 | 1999-08-16 | Primena derivata aril-cikloheksilamina protiv poremećaja centralnog nervnog sistema |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6184236B1 (sh) |
| JP (1) | JP3455142B2 (sh) |
| KR (1) | KR100341194B1 (sh) |
| CN (1) | CN1141936C (sh) |
| AR (1) | AR021770A1 (sh) |
| AT (1) | ATE326219T1 (sh) |
| AU (1) | AU756408B2 (sh) |
| BR (1) | BR9903779A (sh) |
| CA (1) | CA2280455A1 (sh) |
| DE (1) | DE69931316D1 (sh) |
| HR (1) | HRP990256A2 (sh) |
| HU (1) | HUP9902737A3 (sh) |
| ID (1) | ID23107A (sh) |
| IL (1) | IL131399A0 (sh) |
| MA (1) | MA26677A1 (sh) |
| MY (1) | MY133133A (sh) |
| NO (1) | NO993948L (sh) |
| NZ (1) | NZ337243A (sh) |
| PE (1) | PE20000955A1 (sh) |
| PL (1) | PL334949A1 (sh) |
| SG (1) | SG82014A1 (sh) |
| TR (1) | TR199902015A2 (sh) |
| YU (1) | YU38699A (sh) |
| ZA (1) | ZA995212B (sh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1292581B1 (en) * | 2000-06-06 | 2005-08-10 | Warner-Lambert Company LLC | Bicyclic cyclohexylamines and their use as nmda receptor antagonists |
| EP1436258A4 (en) * | 2001-03-08 | 2005-03-23 | Univ Emory | ANTAGONISTS OF THE NMDA RECEPTOR DEPENDENT OF PH |
| DE10153345A1 (de) * | 2001-10-29 | 2003-05-08 | Gruenenthal Gmbh | Substituierte 1H-Chinoxalin-2-on-Verbindungen und substituierte 4-Aryl- und 4-Heteroarylcyclohexan-Verbindungen |
| US20070004805A1 (en) * | 2005-07-01 | 2007-01-04 | Navinta Llc | Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate |
| EP2170334B1 (en) * | 2007-06-29 | 2021-03-17 | Emory University | Nmda receptor antagonists for neuroprotection |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4032766A1 (de) | 1990-10-16 | 1992-04-30 | Basf Ag | Phenylpiperidinoylamine und diese enthaltende arzneimittel |
| DE4117904A1 (de) | 1991-05-31 | 1992-12-03 | Basf Ag | Substituierte n-phenylpiperidine |
| EP0503411B1 (de) | 1991-03-14 | 1995-11-29 | BASF Aktiengesellschaft | Substituierte N-Phenylpiperidine und Arzneimittel daraus |
| AU715216B2 (en) * | 1995-10-26 | 2000-01-20 | Mitsubishi-Tokyo Pharmaceuticals, Inc. | Phenylethanolamine compounds useful as beta3 agonist, process for producing the same, and intermediates in the production of the same |
-
1999
- 1999-08-09 DE DE69931316T patent/DE69931316D1/de not_active Expired - Lifetime
- 1999-08-09 US US09/370,602 patent/US6184236B1/en not_active Expired - Fee Related
- 1999-08-09 AT AT99115114T patent/ATE326219T1/de not_active IP Right Cessation
- 1999-08-13 PE PE1999000826A patent/PE20000955A1/es not_active Application Discontinuation
- 1999-08-13 NZ NZ337243A patent/NZ337243A/xx unknown
- 1999-08-13 IL IL13139999A patent/IL131399A0/xx unknown
- 1999-08-13 CA CA002280455A patent/CA2280455A1/en not_active Abandoned
- 1999-08-13 AR ARP990104079A patent/AR021770A1/es not_active Application Discontinuation
- 1999-08-16 SG SG9903973A patent/SG82014A1/en unknown
- 1999-08-16 MY MYPI99003508A patent/MY133133A/en unknown
- 1999-08-16 JP JP22965899A patent/JP3455142B2/ja not_active Expired - Fee Related
- 1999-08-16 ZA ZA9905212A patent/ZA995212B/xx unknown
- 1999-08-16 HU HU9902737A patent/HUP9902737A3/hu unknown
- 1999-08-16 YU YU38699A patent/YU38699A/sh unknown
- 1999-08-16 ID IDP990791A patent/ID23107A/id unknown
- 1999-08-17 MA MA25736A patent/MA26677A1/fr unknown
- 1999-08-17 PL PL99334949A patent/PL334949A1/xx not_active Application Discontinuation
- 1999-08-17 NO NO993948A patent/NO993948L/no unknown
- 1999-08-17 CN CNB991179110A patent/CN1141936C/zh not_active Expired - Fee Related
- 1999-08-17 KR KR1019990033814A patent/KR100341194B1/ko not_active IP Right Cessation
- 1999-08-17 BR BR9903779-3A patent/BR9903779A/pt not_active IP Right Cessation
- 1999-08-17 AU AU44537/99A patent/AU756408B2/en not_active Ceased
- 1999-08-18 TR TR1999/02015A patent/TR199902015A2/xx unknown
- 1999-08-18 HR HR98115484.2A patent/HRP990256A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TR199902015A3 (tr) | 2000-03-21 |
| KR100341194B1 (ko) | 2002-06-20 |
| HU9902737D0 (en) | 1999-10-28 |
| JP2000109429A (ja) | 2000-04-18 |
| MA26677A1 (fr) | 2004-12-20 |
| ID23107A (id) | 2000-02-24 |
| AR021770A1 (es) | 2002-08-07 |
| NZ337243A (en) | 2000-12-22 |
| HUP9902737A2 (hu) | 2000-06-28 |
| NO993948D0 (no) | 1999-08-17 |
| ATE326219T1 (de) | 2006-06-15 |
| NO993948L (no) | 2000-02-21 |
| CA2280455A1 (en) | 2000-02-18 |
| PE20000955A1 (es) | 2000-09-28 |
| AU756408B2 (en) | 2003-01-09 |
| HRP990256A2 (en) | 2000-04-30 |
| CN1141936C (zh) | 2004-03-17 |
| MY133133A (en) | 2007-10-31 |
| CN1248439A (zh) | 2000-03-29 |
| IL131399A0 (en) | 2001-01-28 |
| BR9903779A (pt) | 2000-09-19 |
| DE69931316D1 (de) | 2006-06-22 |
| TR199902015A2 (xx) | 2000-03-21 |
| HUP9902737A3 (en) | 2001-01-29 |
| SG82014A1 (en) | 2001-07-24 |
| US6184236B1 (en) | 2001-02-06 |
| ZA995212B (en) | 2000-02-18 |
| PL334949A1 (en) | 2000-02-28 |
| AU4453799A (en) | 2000-05-04 |
| JP3455142B2 (ja) | 2003-10-14 |
| KR20000017343A (ko) | 2000-03-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY102087A (en) | Phenethanolamine derivatives. | |
| BG104450A (en) | Bioisosteric substitution of cathechol with indazole in therapeutically active compounds | |
| MY138352A (en) | Benzothiazole derivatives | |
| MY141220A (en) | Pyrazole derivatives as inhibitors of receptor tyrosine kinases | |
| YU49026B (sh) | UPOTREBA 17 Гџ -(N-TERC-BUTILKARBAMOIL)-4-AZA-5-ALFA-ANDROST-1-3-ON ZA PROIZVODNJU LEKA ZA TRETIRANJE ANDROGENE ALOPECIJE | |
| BR0308787A (pt) | Inibidores de metaloproteinase de n-substituìdos-heteroarilóxi-aril-espiro-pirimidina- 2,4,6-triona | |
| YU56995A (sh) | Soli derivata indola | |
| ES2164920T3 (es) | Nuevos derivados heterociclicos y uso medicinal de los mismos. | |
| HUP0203376A2 (hu) | Ciklooxigenáz-2 inhibitor hatású 5-aril-1h-1,2,4-triazol-származékok és ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk | |
| YU38699A (sh) | Primena derivata aril-cikloheksilamina protiv poremećaja centralnog nervnog sistema | |
| SE9802206D0 (sv) | Novel compounds | |
| PT1390371E (pt) | Oxazolo- e furopirimidinas e sua utilizacao em medicamentos contra tumores | |
| EP1228072A4 (en) | PDGF RECEPTOR KINASE INHIBITING COMPOUNDS, THEIR PRODUCTION, CLEANING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | |
| HUP9702241A2 (hu) | 2-Amino-indán-származékok és az ezeket tartalmazó gyógyszerkészítmények | |
| HUP9802087A2 (hu) | Eljárás mánia és bipoláris rendellenesség kezelésére alkalmas gyógyászati készítmények előállítására | |
| CA2096266A1 (en) | Method for the prophylaxis and/or treatment of ulceractive gastrointestinal conditions using a potassium activator and compositions for same | |
| ES2135343A1 (es) | Mejoras en la profilaxis del cancer de mama, o relacionadas con esta. | |
| ATE489399T1 (de) | Antitumor wirksame 2-substituierte estra-1,3, 5(10)-trien-3-yl sulfamate | |
| HK1053109A1 (en) | Substituted homopiperidinyl benzimidazole compounds, pharmaceutical compositions comprising the same, methods for preparing them and the use for the preparation of a medicament of them | |
| BE900959A (fr) | Derives furyles de prostaglandines 16-substituees et procede pour leur fabrication. | |
| HUP9900679A2 (hu) | Simaizom sejtburjánzást gátló benzimidazolszármazékok, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
| NO990609L (no) | Pyrrolidin- og piperidin-derivater | |
| MXPA05006271A (es) | Metodo para el tratamiento de desordenes del movimiento usando derivados de acido barbiturico. | |
| FR2724933B1 (sh) | ||
| DK1267892T3 (da) | Anvendelse af CDP-cholin til behandling af alkoholabstinenssyndrom |