ZA909043B - Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders - Google Patents

Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders

Info

Publication number
ZA909043B
ZA909043B ZA909043A ZA909043A ZA909043B ZA 909043 B ZA909043 B ZA 909043B ZA 909043 A ZA909043 A ZA 909043A ZA 909043 A ZA909043 A ZA 909043A ZA 909043 B ZA909043 B ZA 909043B
Authority
ZA
South Africa
Prior art keywords
asthma
treatment
analogs
skin disorders
certain skin
Prior art date
Application number
ZA909043A
Other languages
English (en)
Inventor
John B Cheng
B Cheng John
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA909043B publication Critical patent/ZA909043B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA909043A 1989-11-13 1990-11-12 Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders ZA909043B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/005221 WO1991007177A1 (en) 1989-11-13 1989-11-13 Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders

Publications (1)

Publication Number Publication Date
ZA909043B true ZA909043B (en) 1992-06-24

Family

ID=22215372

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA909043A ZA909043B (en) 1989-11-13 1990-11-12 Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders

Country Status (17)

Country Link
US (1) US5342842A (ko)
EP (1) EP0428313B1 (ko)
JP (2) JPH0662412B2 (ko)
KR (1) KR930001832B1 (ko)
AT (1) ATE101040T1 (ko)
AU (1) AU627631B2 (ko)
CA (1) CA2029704C (ko)
DE (1) DE69006452T2 (ko)
DK (1) DK0428313T3 (ko)
HU (1) HU212311B (ko)
IE (1) IE63472B1 (ko)
IL (1) IL96260A (ko)
MY (1) MY111474A (ko)
NZ (1) NZ236038A (ko)
PT (1) PT95854B (ko)
WO (2) WO1991007177A1 (ko)
ZA (1) ZA909043B (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5814651A (en) * 1992-12-02 1998-09-29 Pfizer Inc. Catechol diethers as selective PDEIV inhibitors
PL309257A1 (en) * 1992-12-02 1995-10-02 Pfizer Pirocatechin doethers as selective inhibitors of ped iv
US5482944A (en) * 1993-07-13 1996-01-09 Pfizer Inc. Pyrimidones and imidazolinones for treatment of shock
JP2818820B2 (ja) * 1993-11-26 1998-10-30 ファイザー・インク． 抗炎症剤としての３−アリール−２−イソオキサゾリン類
US5502072A (en) * 1993-11-26 1996-03-26 Pfizer Inc. Substituted oxindoles
DK0749428T3 (da) * 1994-03-09 1998-11-16 Pfizer Isooxazolinforbindelser som inhibitorer af TNF-frigivelse
JPH09505081A (ja) * 1994-03-09 1997-05-20 ファイザー・インコーポレーテッド ５−リポキシゲナーゼ阻害物質としてのイソキサゾリン化合物
US5563143A (en) * 1994-09-21 1996-10-08 Pfizer Inc. Catechol diether compounds as inhibitors of TNF release
JP4373497B2 (ja) 1996-06-19 2009-11-25 ローン−プーラン・ロレ・リミテツド 置換されたアザビシクロ化合物、ならびにｔｎｆおよびサイクリックａｍｐホスホジエステラーゼ産生の阻害剤としてのそれらの使用
US6265402B1 (en) 1996-08-27 2001-07-24 Nikken Chemicals Co., Ltd. Use of 2-phenylmorpholin-5-one derivatives
CA2402384A1 (en) * 2000-03-16 2001-09-20 Inflazyme Pharmaceuticals Ltd. Benzylated pde4 inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2401446A1 (de) * 1973-01-16 1974-07-25 Voorhees Pharmazeutische zubereitungen zur linderung von hautproliferationserkrankungen
SU888821A3 (ru) * 1976-12-03 1981-12-07 Шеринг Аг (Инофирма) Способ получени 5-(замещенный фенил)-оксазолидинонов или их серусодержащих аналогов
DE3315797A1 (de) * 1983-04-30 1984-10-31 Beiersdorf Ag, 2000 Hamburg Substituierte phenyl-2-(1h)-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
GB8416140D0 (en) * 1984-06-25 1984-08-01 Fujisawa Pharmaceutical Co Pyrimidinone derivatives
WO1987006576A1 (en) * 1986-04-29 1987-11-05 Pfizer Inc. Calcium independent camp phosphodiesterase inhibitor antidepressant

Also Published As

Publication number Publication date
PT95854B (pt) 1997-11-28
MY111474A (en) 2000-06-30
HU9201575D0 (en) 1993-04-28
IE904058A1 (en) 1991-05-22
IL96260A (en) 1995-11-27
US5342842A (en) 1994-08-30
NZ236038A (en) 1997-03-24
JP2514163B2 (ja) 1996-07-10
AU627631B2 (en) 1992-08-27
PT95854A (pt) 1991-09-13
HU212311B (en) 1996-05-28
AU6653690A (en) 1991-08-01
CA2029704C (en) 1995-02-07
JPH0748255A (ja) 1995-02-21
EP0428313A3 (en) 1991-11-06
IL96260A0 (en) 1991-08-16
JPH03209322A (ja) 1991-09-12
CA2029704A1 (en) 1991-05-14
EP0428313B1 (en) 1994-02-02
KR930001832B1 (ko) 1993-03-15
IE63472B1 (en) 1995-04-19
DE69006452T2 (de) 1994-05-11
JPH0662412B2 (ja) 1994-08-17
DE69006452D1 (de) 1994-03-17
ATE101040T1 (de) 1994-02-15
WO1991007177A1 (en) 1991-05-30
HUT70052A (en) 1995-09-28
KR910009259A (ko) 1991-06-28
EP0428313A2 (en) 1991-05-22
WO1991007178A1 (en) 1991-05-30
DK0428313T3 (da) 1994-03-07

Similar Documents

Publication Publication Date Title
PL292101A1 (en) Method of obtaining novel derivatives of cyclopentylpurine and cyclopentylpyrimidine
HK1008328A1 (en) Endothelin antagonists
ZA944739B (en) Amide and urea derivatives having anti-hypercholesteremic activity their preparation and their therapeutic uses
AU627631B2 (en) Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders
GB9408185D0 (en) New benzamide derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
AU2868689A (en) Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia
GR3005990T3 (ko)
ES2007064A6 (es) Un procedimiento para la obtencion de 4(3h)-oxo-5,6,8-tetrahidropirido (2,3-d)pirimidinas
ZA895387B (en) Novel s-adenosyl methionine decarboxylase inhibitors
PL287073A1 (en) Method of obtaining novel derivatives of benzanilide
DE3666223D1 (en) Anticonvulsant agents
FI103885B1 (fi) Menetelmä terapeuttisesti aktiivisten 1-bentsyyli-4-fenyylipiperatsiinijohdannaisten valmistamiseksi ja välituotteina käyttökelpoisia yhdisteitä
HU912216D0 (en) Process for the production of purinyl-and pirimidinyl - tetrahydrofurane derivatives and medical preparations containing them
ES2059451T3 (es) Derivados de naftotiazepina y su procedimiento de preparacion.
EP0449011A3 (en) Stereoselective process for the preparation of 2-amino-ethanol derivatives having a central analgesic activity and intermediates thereof
ZA885358B (en) Uricosuric composition
EP0272849A3 (en) Use of 2-oxo-imidazolidine derivatives in the treatment of kidney diseases
LU88449I2 (fr) Fleroxacine et ses dérivés pharmaceutiquement acceptables.