ZA200308513B - Peptides and related molecules that bind to TALL-1. - Google Patents

Peptides and related molecules that bind to TALL-1. Download PDF

Info

Publication number: ZA200308513B
Authority: ZA; South Africa
Prior art keywords: amino acid; residue; matter; composition; seq
Prior art date: 2001-05-11

Application number

ZA200308513A

Other languages

English (en)

Inventor

Hosung Min

Hailing Hsu

Fei Xiong

Original Assignee

Amgen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-11

Filing date

2003-10-31

Publication date

2004-09-16

2003-10-31 Application filed by Amgen Inc filed Critical Amgen Inc

2004-09-16 Publication of ZA200308513B publication Critical patent/ZA200308513B/en

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Toxicology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Analytical Chemistry (AREA)
Crystallography & Structural Chemistry (AREA)
Plant Pathology (AREA)
Virology (AREA)
Cell Biology (AREA)
Physics & Mathematics (AREA)
Hematology (AREA)
Dermatology (AREA)
Oncology (AREA)
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ZA200308513A 2001-05-11 2003-10-31 Peptides and related molecules that bind to TALL-1. ZA200308513B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US29019601P	2001-05-11	2001-05-11

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US (5)	US7259137B2 (xx)
EP (4)	EP2845864A3 (xx)
JP (1)	JP4516719B2 (xx)
KR (1)	KR100902687B1 (xx)
CN (3)	CN1970078A (xx)
AT (2)	ATE375361T1 (xx)
AU (1)	AU2002342669C1 (xx)
BG (1)	BG66270B1 (xx)
BR (1)	BR0209546A (xx)
CA (1)	CA2446189C (xx)
CY (1)	CY1107131T1 (xx)
CZ (1)	CZ304592B6 (xx)
DE (1)	DE60222882T2 (xx)
DK (1)	DK1385882T3 (xx)
EA (1)	EA010435B1 (xx)
EE (1)	EE05294B1 (xx)
ES (3)	ES2295404T3 (xx)
HK (3)	HK1059269A1 (xx)
HU (1)	HU229910B1 (xx)
IL (2)	IL158719A0 (xx)
MX (1)	MXPA03010210A (xx)
NO (1)	NO331785B1 (xx)
NZ (2)	NZ542878A (xx)
PL (2)	PL210546B1 (xx)
PT (1)	PT1385882E (xx)
RS (1)	RS51708B (xx)
SI (1)	SI1385882T1 (xx)
SK (1)	SK288175B6 (xx)
WO (1)	WO2002092620A2 (xx)
ZA (1)	ZA200308513B (xx)

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US7879328B2 (en) *	2000-06-16	2011-02-01	Human Genome Sciences, Inc.	Antibodies that immunospecifically bind to B lymphocyte stimulator
ES2609016T3 (es)	2000-06-16	2017-04-18	Human Genome Sciences, Inc.	Anticuerpos que se unen inmunoespecíficamente a BLyS
DE60140773D1 (de)	2000-08-18	2010-01-21	Dyax Corp	Polypeptide zur Bindung an das B-Lymphozyten-stimulatorische Protein (BLyS)
AU2001288301A1 (en) *	2000-08-18	2002-03-04	Human Genome Sciences, Inc.	Binding polypeptides and methods based thereon
UA83458C2 (uk)	2000-09-18	2008-07-25	Байоджен Айдек Ма Інк.	Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
AU2002342669C1 (en) *	2001-05-11	2010-10-07	Amgen, Inc.	Peptides and related molecules that bind to TALL-1
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CA2511823A1 (en)	2002-12-30	2004-07-22	Amgen Inc.	Combination therapy with co-stimulatory factors
US7700317B2 (en)	2003-03-28	2010-04-20	Biogen Idec Ma Inc.	Truncated baff receptors
CA2526402A1 (en)	2003-06-05	2005-01-20	Genentech, Inc.	Blys antagonists and uses thereof
US7605120B2 (en) *	2003-10-22	2009-10-20	Amgen Inc.	Antagonists of the brandykinin B1 receptor
WO2005075511A1 (en) *	2004-01-29	2005-08-18	Genentech, Inc.	Variants of the extracellular domain of bcma and uses thereof
US20070004658A1 (en)	2004-06-21	2007-01-04	Nick Vandeghinste	Method and means for treatment of osteoarthritis
EA011879B1 (ru) *	2004-09-24	2009-06-30	Эмджин Инк.	МОЛЕКУЛЫ С МОДИФИЦИРОВАННЫМ Fc ФРАГМЕНТОМ
CN100378122C (zh) *	2004-12-03	2008-04-02	中国人民解放军第三军医大学	B淋巴细胞刺激因子抑制肽及其制备方法
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US8008453B2 (en)	2005-08-12	2011-08-30	Amgen Inc.	Modified Fc molecules
US9168286B2 (en)	2005-10-13	2015-10-27	Human Genome Sciences, Inc.	Methods and compositions for use in treatment of patients with autoantibody positive disease
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Also Published As

Publication number	Publication date
NO20034980L (no)	2003-12-12
SI1385882T1 (sl)	2008-04-30
EP1385882A4 (en)	2005-09-21
DE60222882D1 (de)	2007-11-22
KR20040012815A (ko)	2004-02-11
US20060135431A1 (en)	2006-06-22
DK1385882T3 (da)	2008-02-11
JP4516719B2 (ja)	2010-08-04
YU95203A (sh)	2006-05-25
PL369570A1 (en)	2005-05-02
SK288175B6 (sk)	2014-04-02
CN1535281A (zh)	2004-10-06
US8507426B2 (en)	2013-08-13
IL158719A (en)	2013-09-30
ATE549354T1 (de)	2012-03-15
ATE375361T1 (de)	2007-10-15
US9139645B2 (en)	2015-09-22
US7737111B2 (en)	2010-06-15
EP2292655A1 (en)	2011-03-09
HUP0700125A3 (en)	2010-01-28
US20100240590A1 (en)	2010-09-23
CN1970077A (zh)	2007-05-30
CZ20033291A3 (cs)	2004-11-10
EP1385882B9 (en)	2009-08-12
ES2527471T3 (es)	2015-01-26
ES2387546T3 (es)	2012-09-25
EP2292655B1 (en)	2012-03-14
HK1059269A1 (en)	2004-06-25
EP1921088B1 (en)	2014-10-08
PL210546B1 (pl)	2012-01-31
CZ304592B6 (cs)	2014-07-23
BR0209546A (pt)	2004-06-29
CY1107131T1 (el)	2012-10-24
BG66270B1 (bg)	2012-11-30
HU229910B1 (hu)	2014-12-29
EP1921088A3 (en)	2009-01-14
HUP0700125A2 (en)	2007-06-28
MXPA03010210A (es)	2004-03-10
US20030195156A1 (en)	2003-10-16
CN1970078A (zh)	2007-05-30
ES2295404T3 (es)	2008-04-16
NO331785B1 (no)	2012-03-26
EP2845864A2 (en)	2015-03-11
CA2446189C (en)	2011-10-18
PL393317A1 (pl)	2011-05-23
CA2446189A1 (en)	2002-11-21
EP1385882A2 (en)	2004-02-04
NO20034980D0 (no)	2003-11-10
NZ529267A (en)	2006-05-26
US20160176926A1 (en)	2016-06-23
EA200301241A1 (ru)	2004-08-26
AU2002342669B2 (en)	2005-09-22
WO2002092620A2 (en)	2002-11-21
NZ542878A (en)	2007-06-29
KR100902687B1 (ko)	2009-06-15
EE05294B1 (et)	2010-04-15
JP2004533249A (ja)	2004-11-04
EP2845864A3 (en)	2015-06-10
US7259137B2 (en)	2007-08-21
HK1151545A1 (en)	2012-02-03
EE200300552A (et)	2004-02-16
EP1921088A2 (en)	2008-05-14
DE60222882T2 (de)	2008-07-10
SK14892003A3 (en)	2004-11-03
AU2002342669C1 (en)	2010-10-07
HK1207390A1 (en)	2016-01-29
EP1385882B1 (en)	2007-10-10
EA010435B1 (ru)	2008-08-29
IL158719A0 (en)	2004-05-12
WO2002092620A3 (en)	2003-08-21
US20140234334A1 (en)	2014-08-21
RS51708B (sr)	2011-10-31
BG108349A (bg)	2004-11-30
CN100448891C (zh)	2009-01-07
PT1385882E (pt)	2008-01-11

Publication	Publication Date	Title
AU2002342669C1 (en)	2010-10-07	Peptides and related molecules that bind to TALL-1
AU2002342669A1 (en)	2003-05-01	Peptides and related molecules that bind to TALL-1
JP2004533249A5 (xx)	2006-01-05
EP1278772A2 (en)	2003-01-29	Glucagon antagonists
JP2010142236A (ja)	2010-07-01	神経増殖因子の活性を調節するペプチド及び関連分子
AU2001257173B2 (en)	2005-09-22	Apo-ai/aii peptide derivatives
AU2001257173A1 (en)	2002-01-24	Apo-AI/AII peptide derivatives
US20020090646A1 (en)	2002-07-11	Calcitonin-related molecules