YU67803A - Karbamatna jedinjenja za upotrebu u sprečavanju ili lečenju bipolarnih poremaćaja - Google Patents
Karbamatna jedinjenja za upotrebu u sprečavanju ili lečenju bipolarnih poremaćajaInfo
- Publication number
- YU67803A YU67803A YU67803A YUP67803A YU67803A YU 67803 A YU67803 A YU 67803A YU 67803 A YU67803 A YU 67803A YU P67803 A YUP67803 A YU P67803A YU 67803 A YU67803 A YU 67803A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- preventing
- bipolar disorder
- phenyl
- alkyl
- treating bipolar
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Ovaj pronalazak se odnosi na postupak za sprečavanje ili lečenje bipolarnog poremećaja koji čini davanje subjektu kome je potrebno terapeutski efikasne količine jedinjenja formule (I). Formula (I): u kojoj fenil je supstituisan sa X sa jednim do pet atoma halogena izabranih iz grupe koju čine fluor, hlor, brom i jod; i R1 i R2 su nezavisno izabrani iz grupe koju čine vodonik i C1-C4 alkil; gde C1-C4 alkil je opciono supstituisan sa fenilom (gde je fenil opciono supstituisan sa supstituentima nezavisno izabranim iz grupe koju čine halogen, C1-C4 alkil, C1-C4 alkoksi, amino, nitro i cijano).[This invention is directed to a method for preventing or treating bipolar disorder comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I): Formula (I); wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R1 and R2 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27168101P | 2001-02-27 | 2001-02-27 | |
| US10/081,766 US6562867B2 (en) | 2001-02-27 | 2002-02-21 | Carbamate compounds for use in preventing or treating bipolar disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU67803A true YU67803A (sh) | 2006-08-17 |
| RS50677B RS50677B (sr) | 2010-06-30 |
Family
ID=26765948
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6562867B2 (sh) |
| EP (1) | EP1408953B1 (sh) |
| JP (1) | JP4276837B2 (sh) |
| KR (1) | KR100946944B1 (sh) |
| CN (1) | CN1250215C (sh) |
| AT (1) | ATE324108T1 (sh) |
| BR (1) | BR0207644A (sh) |
| CA (1) | CA2439475C (sh) |
| CY (1) | CY1105330T1 (sh) |
| CZ (1) | CZ20032300A3 (sh) |
| DE (1) | DE60210976T2 (sh) |
| DK (1) | DK1408953T3 (sh) |
| ES (1) | ES2262801T3 (sh) |
| HK (1) | HK1063436A1 (sh) |
| HU (1) | HUP0303243A3 (sh) |
| IL (1) | IL157590A0 (sh) |
| MX (1) | MXPA03007717A (sh) |
| MY (1) | MY129304A (sh) |
| NO (1) | NO20033802L (sh) |
| NZ (1) | NZ527988A (sh) |
| PL (1) | PL364638A1 (sh) |
| PT (1) | PT1408953E (sh) |
| RS (1) | RS50677B (sh) |
| RU (1) | RU2300372C2 (sh) |
| TW (1) | TWI250872B (sh) |
| WO (1) | WO2002067921A1 (sh) |
| ZA (1) | ZA200307465B (sh) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ2003445A3 (cs) * | 2000-07-21 | 2004-08-18 | Ortho@Mcneilápharmaceuticalźáinc | Karbamátové sloučeniny pro prevenci nebo léčbu neuropatické bolesti a bolesti asociované s histaminovou a migrenózní bolestí hlavy |
| NZ527990A (en) * | 2001-02-27 | 2006-01-27 | Ortho Mcneil Pharm Inc | Carbamate compounds for use in preventing or treating neurodegenerative disorders |
| MXPA03007720A (es) * | 2001-02-27 | 2004-11-12 | Johnson & Johnson | Compuestos de carbamato para su uso en la prevencion o el tratamiento de transtornos de ansiedad. |
| RU2303445C2 (ru) | 2001-07-16 | 2007-07-27 | Орто-Макнейл Фармасьютикал, Инк. | Карбаматные соединения для применения для предотвращения или лечения невропатической боли и боли, связанной с кластерной и мигреневой головной болью |
| ES2342185T3 (es) * | 2004-09-16 | 2010-07-02 | Janssen Pharmaceutica Nv | Uso de (di)carbamatos de 2-fenil-1,2-etanodiol para el tratamiento de la epileptogenesis. |
| CN101217949B (zh) * | 2005-06-08 | 2012-10-17 | 爱思开生物制药株式会社 | 治疗睡眠-清醒病症 |
| US20070021501A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods of treating epileptogenesis |
| CN101568362A (zh) * | 2006-10-30 | 2009-10-28 | 詹森药业有限公司 | 治疗抑郁症的方法 |
| CN101568333A (zh) * | 2006-10-31 | 2009-10-28 | 詹森药业有限公司 | 广泛性发育障碍的治疗 |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| CN105164103B (zh) * | 2013-03-12 | 2019-12-06 | 比皮艾思药物研发有限公司 | 苯基氨基甲酸酯化合物和含有其的预防或治疗记忆缺失相关疾病的组合物 |
| US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
| CN110290788A (zh) * | 2016-12-14 | 2019-09-27 | 爱思开生物制药株式会社 | 氨基甲酸酯化合物用于预防、缓解或治疗双相障碍的用途 |
| CA3065522A1 (en) | 2017-06-02 | 2018-12-06 | Jazz Pharmaceuticals Ireland Limited | Methods and compositions for treating excessive sleepiness |
| US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3278380A (en) * | 1962-02-06 | 1966-10-11 | Armour Pharma | Methods of calming employing diphenyl hydroxy carbamate compounds |
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| US5698588A (en) * | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
-
2002
- 2002-02-21 RU RU2003128997/14A patent/RU2300372C2/ru active
- 2002-02-21 BR BR0207644-6A patent/BR0207644A/pt not_active Application Discontinuation
- 2002-02-21 NZ NZ527988A patent/NZ527988A/en unknown
- 2002-02-21 HU HU0303243A patent/HUP0303243A3/hu unknown
- 2002-02-21 PT PT02724984T patent/PT1408953E/pt unknown
- 2002-02-21 CZ CZ20032300A patent/CZ20032300A3/cs unknown
- 2002-02-21 DK DK02724984T patent/DK1408953T3/da active
- 2002-02-21 AT AT02724984T patent/ATE324108T1/de active
- 2002-02-21 US US10/081,766 patent/US6562867B2/en not_active Expired - Lifetime
- 2002-02-21 CN CNB028089170A patent/CN1250215C/zh not_active Expired - Fee Related
- 2002-02-21 RS YUP-678/03A patent/RS50677B/sr unknown
- 2002-02-21 JP JP2002567288A patent/JP4276837B2/ja not_active Expired - Lifetime
- 2002-02-21 PL PL02364638A patent/PL364638A1/xx not_active Application Discontinuation
- 2002-02-21 WO PCT/US2002/005297 patent/WO2002067921A1/en active IP Right Grant
- 2002-02-21 MX MXPA03007717A patent/MXPA03007717A/es active IP Right Grant
- 2002-02-21 DE DE60210976T patent/DE60210976T2/de not_active Expired - Lifetime
- 2002-02-21 IL IL15759002A patent/IL157590A0/xx not_active IP Right Cessation
- 2002-02-21 KR KR1020037011296A patent/KR100946944B1/ko active IP Right Grant
- 2002-02-21 ES ES02724984T patent/ES2262801T3/es not_active Expired - Lifetime
- 2002-02-21 CA CA2439475A patent/CA2439475C/en not_active Expired - Fee Related
- 2002-02-21 EP EP02724984A patent/EP1408953B1/en not_active Expired - Lifetime
- 2002-02-27 TW TW091103500A patent/TWI250872B/zh active
- 2002-02-27 MY MYPI20020691A patent/MY129304A/en unknown
-
2003
- 2003-08-26 NO NO20033802A patent/NO20033802L/no not_active Application Discontinuation
- 2003-09-25 ZA ZA200307465A patent/ZA200307465B/en unknown
-
2004
- 2004-08-20 HK HK04106261A patent/HK1063436A1/xx not_active IP Right Cessation
-
2006
- 2006-06-21 CY CY20061100844T patent/CY1105330T1/el unknown
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