MXPA03007717A - Compuestos de carbamato para su uso en la prevencion o tratamiento de trastornos bipolares. - Google Patents

Compuestos de carbamato para su uso en la prevencion o tratamiento de trastornos bipolares.

Info

Publication number
MXPA03007717A
MXPA03007717A MXPA03007717A MXPA03007717A MXPA03007717A MX PA03007717 A MXPA03007717 A MX PA03007717A MX PA03007717 A MXPA03007717 A MX PA03007717A MX PA03007717 A MXPA03007717 A MX PA03007717A MX PA03007717 A MXPA03007717 A MX PA03007717A
Authority
MX
Mexico
Prior art keywords
preventing
bipolar disorder
phenyl
alkyl
treating bipolar
Prior art date
Application number
MXPA03007717A
Other languages
English (en)
Inventor
E Twyman Roy
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MXPA03007717A publication Critical patent/MXPA03007717A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La invencion esta dirigida a un metodo para la prevencion o el tratamiento del trastorno bipolar que comprende administrar a un sujeto en necesidad del mismo una cantidad terapeuticamente efectiva de un compuesto de la formula (I): (Ver formula) en donde el fenilo esta sustituido en X con uno a cinco atomos de halogeno seleccionado del grupo que consiste en fluor, cloro, bromo y yodo; y R1 y R2 se seleccionan independientemente del grupo que consiste en hidrogeno y alquilo de C1-C4; en donde el alquilo de C1-C4 se sustituye opcionalmente con fenilo (en donde el fenilo se sustituye opcionalmente con sustituyentes seleccionados independientemente del grupo que consiste en halogeno, alquilo de C1-C4, alcoxi de C1-C4, amino, nitro y ciano).
MXPA03007717A 2001-02-27 2002-02-21 Compuestos de carbamato para su uso en la prevencion o tratamiento de trastornos bipolares. MXPA03007717A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27168101P 2001-02-27 2001-02-27
PCT/US2002/005297 WO2002067921A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder
US10/081,766 US6562867B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder

Publications (1)

Publication Number Publication Date
MXPA03007717A true MXPA03007717A (es) 2005-11-08

Family

ID=26765948

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03007717A MXPA03007717A (es) 2001-02-27 2002-02-21 Compuestos de carbamato para su uso en la prevencion o tratamiento de trastornos bipolares.

Country Status (27)

Country Link
US (1) US6562867B2 (es)
EP (1) EP1408953B1 (es)
JP (1) JP4276837B2 (es)
KR (1) KR100946944B1 (es)
CN (1) CN1250215C (es)
AT (1) ATE324108T1 (es)
BR (1) BR0207644A (es)
CA (1) CA2439475C (es)
CY (1) CY1105330T1 (es)
CZ (1) CZ20032300A3 (es)
DE (1) DE60210976T2 (es)
DK (1) DK1408953T3 (es)
ES (1) ES2262801T3 (es)
HK (1) HK1063436A1 (es)
HU (1) HUP0303243A3 (es)
IL (1) IL157590A0 (es)
MX (1) MXPA03007717A (es)
MY (1) MY129304A (es)
NO (1) NO20033802L (es)
NZ (1) NZ527988A (es)
PL (1) PL364638A1 (es)
PT (1) PT1408953E (es)
RS (1) RS50677B (es)
RU (1) RU2300372C2 (es)
TW (1) TWI250872B (es)
WO (1) WO2002067921A1 (es)
ZA (1) ZA200307465B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2003445A3 (cs) * 2000-07-21 2004-08-18 Ortho@Mcneilápharmaceuticalźáinc Karbamátové sloučeniny pro prevenci nebo léčbu neuropatické bolesti a bolesti asociované s histaminovou a migrenózní bolestí hlavy
NZ527990A (en) * 2001-02-27 2006-01-27 Ortho Mcneil Pharm Inc Carbamate compounds for use in preventing or treating neurodegenerative disorders
MXPA03007720A (es) * 2001-02-27 2004-11-12 Johnson & Johnson Compuestos de carbamato para su uso en la prevencion o el tratamiento de transtornos de ansiedad.
RU2303445C2 (ru) 2001-07-16 2007-07-27 Орто-Макнейл Фармасьютикал, Инк. Карбаматные соединения для применения для предотвращения или лечения невропатической боли и боли, связанной с кластерной и мигреневой головной болью
ES2342185T3 (es) * 2004-09-16 2010-07-02 Janssen Pharmaceutica Nv Uso de (di)carbamatos de 2-fenil-1,2-etanodiol para el tratamiento de la epileptogenesis.
CN101217949B (zh) * 2005-06-08 2012-10-17 爱思开生物制药株式会社 治疗睡眠-清醒病症
US20070021501A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods of treating epileptogenesis
CN101568362A (zh) * 2006-10-30 2009-10-28 詹森药业有限公司 治疗抑郁症的方法
CN101568333A (zh) * 2006-10-31 2009-10-28 詹森药业有限公司 广泛性发育障碍的治疗
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
CN105164103B (zh) * 2013-03-12 2019-12-06 比皮艾思药物研发有限公司 苯基氨基甲酸酯化合物和含有其的预防或治疗记忆缺失相关疾病的组合物
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
CN110290788A (zh) * 2016-12-14 2019-09-27 爱思开生物制药株式会社 氨基甲酸酯化合物用于预防、缓解或治疗双相障碍的用途
CA3065522A1 (en) 2017-06-02 2018-12-06 Jazz Pharmaceuticals Ireland Limited Methods and compositions for treating excessive sleepiness
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol

Also Published As

Publication number Publication date
ES2262801T3 (es) 2006-12-01
KR100946944B1 (ko) 2010-03-15
CY1105330T1 (el) 2010-03-03
TWI250872B (en) 2006-03-11
NO20033802L (no) 2003-10-22
ATE324108T1 (de) 2006-05-15
HUP0303243A3 (en) 2012-07-30
CA2439475A1 (en) 2002-09-06
EP1408953A1 (en) 2004-04-21
NO20033802D0 (no) 2003-08-26
CA2439475C (en) 2010-05-18
IL157590A0 (en) 2004-03-28
US20020198257A1 (en) 2002-12-26
WO2002067921A1 (en) 2002-09-06
RU2003128997A (ru) 2005-03-20
BR0207644A (pt) 2004-03-09
HK1063436A1 (en) 2004-12-31
CN1250215C (zh) 2006-04-12
US6562867B2 (en) 2003-05-13
PL364638A1 (en) 2004-12-13
YU67803A (sh) 2006-08-17
JP4276837B2 (ja) 2009-06-10
DK1408953T3 (da) 2006-08-21
MY129304A (en) 2007-03-30
DE60210976D1 (de) 2006-06-01
HUP0303243A2 (hu) 2004-01-28
KR20030087010A (ko) 2003-11-12
RS50677B (sr) 2010-06-30
CN1505506A (zh) 2004-06-16
CZ20032300A3 (cs) 2005-01-12
NZ527988A (en) 2006-01-27
PT1408953E (pt) 2006-07-31
ZA200307465B (en) 2005-03-17
DE60210976T2 (de) 2007-05-24
RU2300372C2 (ru) 2007-06-10
EP1408953B1 (en) 2006-04-26
JP2004533415A (ja) 2004-11-04

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