WO2015111748A1 - 皮膚マスキング材 - Google Patents

皮膚マスキング材 Download PDF

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Publication number
WO2015111748A1
WO2015111748A1 PCT/JP2015/052090 JP2015052090W WO2015111748A1 WO 2015111748 A1 WO2015111748 A1 WO 2015111748A1 JP 2015052090 W JP2015052090 W JP 2015052090W WO 2015111748 A1 WO2015111748 A1 WO 2015111748A1
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WO
WIPO (PCT)
Prior art keywords
skin
masking material
film layer
film
adhesive layer
Prior art date
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PCT/JP2015/052090
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English (en)
French (fr)
Japanese (ja)
Inventor
山本　敏幸
Original Assignee
株式会社メディカルフロント
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 株式会社メディカルフロント filed Critical 株式会社メディカルフロント
Priority to KR1020157034370A priority Critical patent/KR101811937B1/ko
Priority to CN201580015231.2A priority patent/CN106102513B/zh
Priority to JP2015559160A priority patent/JP6147874B2/ja
Publication of WO2015111748A1 publication Critical patent/WO2015111748A1/ja

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    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D44/00—Other cosmetic or toiletry articles, e.g. for hairdressers' rooms
    • A45D44/22—Face shaping devices, e.g. chin straps; Wrinkle removers, e.g. stretching the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/87—Polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations

Definitions

  • the present invention relates to a skin masking material to be applied to the skin.
  • Patent Document 1 discloses a skin masking material in which a pressure-sensitive adhesive layer is laminated on one surface of a film layer and fine irregularities are formed on the other surface of the film layer.
  • a pressure-sensitive adhesive layer is laminated on one surface of a film layer and fine irregularities are formed on the other surface of the film layer.
  • the present invention provides a skin masking material that is applied to the skin to conceal the site when a portion that appears to be abnormal on the skin has occurred, and is applied to the surface of the applied skin masking material. Furthermore, the present invention provides a skin masking material having a good makeup paste when a cosmetic is applied.
  • the inventor of the present invention has examined the cosmetic masking material as follows.
  • Cosmetics such as foundations and concealers vary greatly in the range of the average particle size of the powder in the range of about 0.1 to 60 ⁇ m depending on the type. Depending on the size of the average particle size, it is considered that the height difference of the unevenness suitable for holding the powder varies.
  • corrugation formed in the other surface are not examined. Even if the skin masking material described in Patent Document 1 is used, the difference in height of the irregularities formed on the other surface is small, so that the powder contained in the cosmetic is not sufficiently retained on the other surface, and the makeup paste is poor. it is conceivable that.
  • the present inventor said that whether or not the skin masking material has good makeup is determined by the ratio between the height difference of the unevenness formed on the other surface and the particle size of the powder contained in the cosmetic. Under consideration, a skin masking material having a ten-point average roughness Rz on the other side larger than the average particle diameter of the powder contained in the cosmetic was used. As a result, the present inventors have found that a skin masking material with a significantly superior makeup paste can be provided compared to the case where Rz on the other surface is less than the average particle size.
  • the skin masking material according to the present invention is a makeup in which a pressure-sensitive adhesive layer is laminated on at least a part of one surface of a stretchable film layer and applied to the other surface of the film layer.
  • the average particle diameter of the powder contained in the material is d and the thickness of the film layer is w
  • the ten-point average roughness Rz of the other surface is d ⁇ Rz ⁇ 60d
  • the skin masking material according to the present invention has a pressure-sensitive adhesive layer laminated on at least a part of one surface of the stretchable film layer, and when the thickness of the film layer is w, Ten-point average roughness Rz is 6 ⁇ m ⁇ Rz ⁇ 40 ⁇ m, and Rz ⁇ w.
  • fine particles can be dispersed in the film layer so that the total light transmittance of the film layer is 75 to 90%.
  • the water vapor transmission rate may be 400 g / (m 2 ⁇ day) or more.
  • the pressure-sensitive adhesive layer may contain 10 to 50% by weight of an organic compound having a polar group that is liquid at room temperature.
  • the adhesive layer may contain a medicinal component for the skin.
  • the medicinal component may include a compound selected from the group consisting of ⁇ -hydroxy acids, salicylic acid, and mixtures thereof.
  • the medicinal component may contain an antibacterial agent.
  • the antibacterial agent may include a compound selected from the group consisting of isopropylmethylphenol, a silver-based antibacterial agent, and a mixture thereof.
  • the medicinal component may include a non-steroidal anti-inflammatory drug.
  • the material of the film layer may be polyether polyurethane or polyester polyurethane.
  • the thickness w of the film layer may be 6 ⁇ m ⁇ w ⁇ 100 ⁇ m.
  • the skin masking material according to the present invention having the above-described configuration, when the ten-point average roughness Rz of the other surface is d ⁇ Rz ⁇ 60d, the height difference of the unevenness formed on the other surface is a cosmetic. Is larger than the average particle diameter d of the powder contained in the powder, most of the powder enters the recesses of the recesses and is held in the recesses. Furthermore, in this case, since the Rz on the other surface is 60 times or less the average particle diameter d, the user can wipe off the powder that has entered the recess. In this case, since the user can adjust the amount of the cosmetic applied to the other side, the user can finely adjust the color of the other side to match the skin color while avoiding thick makeup. .
  • the skin masking material according to the present invention when the ten-point average roughness Rz of the other surface is 6 ⁇ m ⁇ Rz ⁇ 40 ⁇ m, the unevenness formed on the other surface compared to the conventional skin masking material. The height difference is large, and the powder contained in the cosmetic is easily held in the recess. Further, in this case, since the Rz of the other surface is Rz ⁇ 40 ⁇ m, the height difference of the unevenness is not too large, and the powder held in the recess is particularly easy to wipe off. In this case, since the user can easily correct the makeup, it is not necessary to carefully adjust the hue.
  • the skin masking material when a site that appears to be abnormal in appearance has occurred in the skin, the skin masking material is applied to the skin in order to conceal the site, and the skin masking material applied It is possible to provide a skin masking material having a good makeup paste when a cosmetic material is further put on the surface.
  • Sectional drawing which shows the skin masking material which concerns on Embodiment 1,2.
  • Sectional drawing which shows the skin masking material which concerns on other embodiment in the case of using the composite film which laminated
  • Sectional drawing which shows the skin masking material which concerns on other embodiment in the case of using the composite film which laminated
  • Sectional drawing which shows the skin masking material which concerns on other embodiment at the time of laminating
  • (A) is sectional drawing which shows the skin masking material which concerns on other embodiment when the part by which an adhesive layer is not laminated
  • (b) is one surface of a film layer. It is sectional drawing which shows the skin masking material which concerns on other embodiment at the time of providing the part in which an adhesive layer is not laminated
  • (c) is skin masking shown in (b) It is a front view at the time of seeing a material from the skin contact surface side of an adhesive layer.
  • the skin masking material 2a which concerns on Embodiment 1 is the laminated body 14 provided with the film layer 4a and the adhesive layer 6a.
  • the pressure-sensitive adhesive layer 6a is laminated on the one surface 12 of the film layer 4a.
  • the film layer 4a has elasticity. When the skin masking material 2a is applied to the skin, at least a part of the film layer 4a is stretched following the curved surface of the skin.
  • the skin masking material 2a can be affixed so that the entire skin contact surface 16 facing the one surface 12 in the adhesive layer 6a is in close contact with the curved skin.
  • the film layer 4a In order for the film layer 4a to have elasticity, it is preferable to use a film having a tensile modulus of 0.2 to 5 MPa as a material for the film layer 4a.
  • the tensile elastic modulus is less than 0.2 MPa, the film layer 4a expands and contracts more than necessary, so that it is difficult to remove the skin masking material 2a from the skin by picking it with a fingertip.
  • the tensile modulus exceeds 5 MPa, the film layer 4a does not follow the curved surface of the skin, and thus there is a possibility that the skin masking material 2a is peeled off from the skin in a short time after being applied to the skin.
  • the pressure exceeds 5 MPa, after the skin masking material 2a is pasted, the user feels the skin tight, and the user feels uncomfortable.
  • Examples of the material of the film layer 4a include a urethane resin film, a vinyl acetate film, an acrylic resin film, and a silicone resin film.
  • the acrylic resin-based film contains, as a main component, an alkyl acrylate having 1 to 8 carbon atoms in the alkyl group and an alkyl methacrylate, and a polymerizable monomer or prepolymer that can be copolymerized with these and has a hydrogen bonding ability. Examples thereof include a film made of a copolymer containing 0 to 20 mol% of units.
  • Examples of the acrylic resin film include hydroxyalkyl acrylates such as hydroxyethyl acrylate (HEA) and acrylamides having a hydroxyl group such as hydroxyethyl acrylamide (HEAA).
  • methyl methacrylate is exemplified as the alkyl methacrylate.
  • an ethyl acrylate is illustrated as an alkyl acrylate here.
  • the molar ratio of methyl methacrylate to ethyl acrylate is, for example, 40:90 to 40: 180.
  • the acrylic resin film obtained by copolymerizing these has a moisture permeability of 900 to 1,300 g / (m 2 ⁇ day) when the surface is smooth and the thickness is 30 ⁇ m.
  • the alkyl acrylate is exemplified by butyl acrylate.
  • the molar ratio of methyl methacrylate to butyl acrylate is, for example, 10:16 to 10:25.
  • the acrylic resin film obtained by copolymerizing these has a smooth surface and a thickness of 30 ⁇ m, the moisture permeability is about 900 g / (m 2 ⁇ day).
  • Examples of the material of the adhesive layer 6a include an adhesive selected from the group consisting of an acrylic adhesive, a rubber adhesive, a silicone adhesive, a urethane adhesive, and a mixture thereof.
  • acrylic adhesives, silicone adhesives, and urethane adhesives have higher moisture permeability than rubber adhesives, and therefore consist of acrylic adhesives, silicone adhesives, urethane adhesives, and mixtures thereof. It is preferable to obtain a skin masking material 2a having high moisture permeability by using an adhesive selected from the group as a material for the adhesive layer 6a.
  • the material of the pressure-sensitive adhesive layer 6a is more preferably an acrylic pressure-sensitive adhesive.
  • an acrylic pressure-sensitive adhesive is used, the moisture permeability of the pressure-sensitive adhesive layer 6a can be adjusted by a combination of monomers.
  • HEAA hydroxyethyl acrylamide
  • VA vinyl acetate
  • the adhesive layer 6a is High moisture permeability.
  • the adhesive layer 6a can be made into a gel form.
  • the pressure-sensitive adhesive layer 6a When the pressure-sensitive adhesive layer 6a is in a gel form, keratin damage can be suppressed when the skin masking material 2a is applied to the skin or peeled off from the skin. Since the acrylic pressure-sensitive adhesive is a high molecular weight substance and has adhesiveness, when the acrylic pressure-sensitive adhesive is used, the pressure-sensitive adhesive layer 6a hardly contains a low molecular weight additive having a molecular weight of 1,000 or less that can cause allergies. .
  • the thickness of the pressure-sensitive adhesive layer 6a is preferably 10 to 30 ⁇ m.
  • the skin masking material 2a does not have a predetermined adhesive force with respect to the skin depending on the type of the adhesive used as the material of the adhesive layer 6a. If the thickness exceeds 30 ⁇ m, not only the skin masking material 2a may stick to the edges of the adhesive layer 6a after the skin masking material 2a is applied, but the skin masking material 2a may be caught on fingers or clothes. It can cause peeling. Moreover, when it exceeds 30 micrometers, it is difficult to give sufficient moisture permeability to the adhesive layer 6a depending on the kind of adhesive used as a raw material.
  • the adhesive strength of the adhesive layer 6a is a value measured by 180 degree peeling according to the peel strength test method of the adhesive based on JIS K 6854-2, and the adhesive strength on the SUS plate of the skin masking material 2 is 0. 1 to 10 (N / 25 mm) is preferable. If the adhesive strength is less than 0.1 N / 25 mm, the adhesive strength is too weak, so that the skin masking material 2a may peel from the skin in a short time. If the adhesive strength exceeds 10 N / 25 mm, the adhesive strength is too strong. Therefore, when the skin masking material 2a is peeled from the skin, the skin may be stimulated and the keratin may be damaged.
  • the ten-point average roughness Rz of the other surface 10a of the film layer 4a is 1 of d when the average particle diameter of the powder contained in cosmetics such as foundation and concealer applied to the other surface 10a of the film layer 4a is d. 60 times, that is, d ⁇ Rz ⁇ 60d. Further, Rz of the other surface 10 is w or less, that is, Rz ⁇ w, where w is the thickness of the film layer 4a.
  • the Rz of the other surface 10a is obtained by measuring the surface shape of the other surface 10a using a surface roughness measuring machine under the conditions of a reference length of 500 ⁇ m and a cutoff value of 200 ⁇ m in accordance with JIS B 0601: 2001. This is the value obtained.
  • the average particle diameter d of the powder contained in the cosmetic is measured by a particle diameter analysis / laser diffraction method in accordance with JIS Z 8825-1: 2001. The median diameter.
  • the average particle diameter d of the particles contained in cosmetics such as foundations and concealers has a width of about 0.1 ⁇ m ⁇ d ⁇ 60 ⁇ m.
  • Rz of the other surface 10a is 1 to 60 times d. Since the Rz of the other surface 10a is larger than the average particle diameter d, most of the powder contained in the cosmetic enters the concave portion of the concave and convex portions formed on the other surface 10a and is held in the concave portion.
  • the film layer 4a has elasticity, so the recess expands and contracts according to the shape of the powder, and the Rz of the other surface 10a is 1 times d.
  • the powder can be held on the other surface 10a.
  • the skin masking material 2a is affixed to the skin to conceal the part, and is applied to the surface of the affixed skin masking material 2a. Furthermore, when applying cosmetics, the makeup paste is good.
  • a urethane film having an embossed surface has been produced, and the surface properties thereof are an arithmetic average roughness Ra of less than 0.3 ⁇ m and an Rz of about 1 ⁇ m or less. Even when a powder having an average particle diameter d in the range of 2 to 60 ⁇ m is applied to the surface of a conventional urethane film, the powder slides down the film surface.
  • the Rz of the other surface 10a is 2 ⁇ m ⁇ Rz ⁇ 120 ⁇ m and Rz ⁇ w when d is 2 ⁇ m.
  • d is 6 ⁇ m, 6 ⁇ m ⁇ Rz ⁇ 360 ⁇ m and Rz ⁇ w.
  • d is 60 ⁇ m, 60 ⁇ m ⁇ Rz ⁇ 3,600 ⁇ m and Rz ⁇ w.
  • the skin masking material 2b Compared with the conventional skin masking material, the skin masking material 2b has a large difference in level of the unevenness formed on the other surface 10b, and the powder contained in the cosmetic is easily held in the recess. Furthermore, since the skin masking material 2b has an Rz of the other surface 10b of Rz ⁇ 40 ⁇ m, the height difference of the unevenness is not too large, and the powder held in the recesses is particularly easy to wipe off. Since the user can easily correct the makeup, it is not necessary to carefully adjust the hue.
  • the Rz of the other surface 10b is preferably 10 ⁇ m ⁇ Rz ⁇ 40 ⁇ m and Rz ⁇ w.
  • a plurality of types of cosmetics such as concealer and foundation are applied to the other surface 10b
  • a plurality of types of powders having different average particle diameters d are held in the recesses of the unevenness formed on the other surface 10b.
  • 6 ⁇ m ⁇ Rz ⁇ 10 ⁇ m if 10 ⁇ m ⁇ Rz ⁇ 40 ⁇ m, the difference in height of the unevenness is sufficiently large, so that the foundation powder applied on the concealer powder is sufficiently retained.
  • Rz of the other surface 10 is more preferably 17 ⁇ m ⁇ Rz ⁇ 35 ⁇ m and Rz ⁇ w.
  • a large amount of powder can be held in the irregularities, and therefore, makeup paste is particularly good when a plurality of types of cosmetics are applied.
  • the size of the unevenness of the unevenness is close to the unevenness of the unevenness on the surface of the skin. The cosmetic can be wiped off from the other surface 10b with a feeling close to that when the cosmetic is wiped off from the other side 10b.
  • the skin masking material 2b also has a makeup paste when the Rz of the other surface 10b is d ⁇ Rz ⁇ 60d with respect to the average particle diameter d of the powder contained in the cosmetic applied to the other surface 10b. Good effect is demonstrated.
  • the maximum range of the average particle diameter d of the powder that exhibits a good effect of the cosmetic paste is 0.1 ⁇ m ⁇ d ⁇ 40 ⁇ m and d ⁇ w.
  • the maximum range of the average particle diameter d of the powder exhibiting a good effect of cosmetic paste is about 0.17 ⁇ m ⁇ d ⁇ 40 ⁇ m and d ⁇ w.
  • the maximum range of the average particle diameter d of the powder exhibiting a good effect of cosmetic paste is about 0.28 ⁇ m ⁇ d ⁇ 35 ⁇ m and d ⁇ w.
  • the arithmetic average roughness Ra defined in accordance with JIS B 0601: 2001 for the other surfaces (10a, 10b) is 0.15d ⁇ Ra ⁇ 3d and Ra ⁇ (w / 2). preferable. Specifically, when d is 2 ⁇ m, 0.3 ⁇ m ⁇ Ra ⁇ 6 ⁇ m and Ra ⁇ (w / 2). When d is 6 ⁇ m, 0.9 ⁇ m ⁇ Ra ⁇ 18 ⁇ m and Ra ⁇ (w / 2). If the other surface (10a, 10b) has such a surface property, it is suitable for holding the powder contained in the cosmetic.
  • the concave portion is a substantially cylindrical hole shape, a substantially prismatic hole shape, a substantially mortar-shaped hole shape, a groove shape, and a mixture of these shapes. It may be a shape selected from the group consisting of shapes.
  • the depth of the concave portion formed on the other surface (10a, 10b) and the height of the convex portion may be different for each concave portion or each convex portion.
  • the incident light to the film layer 4a is refracted by the unevenness or diffused by diffuse reflection as compared with a smooth case.
  • the masking properties of the masking materials (2a, 2b) are high.
  • Rz on the other surface (10a, 10b) is large, the total light transmittance of the film layer 4a is low, and the masking property of the skin masking material (2a, 2b) is high.
  • the diameter of the hole is preferably 3 to 35 ⁇ m.
  • the width of the groove is preferably 5 to 35 ⁇ m.
  • the uneven shape formed on the other surface (10a, 10b) is similar to the uneven shape provided on the surface of natural leather or artificial leather.
  • the masking property of the skin masking material (2a, 2b) is high, the paste on the other side (10a, 10b) is good, and the skin masking material (2a, 2b) is applied after the cosmetic is applied.
  • the difference in appearance between the coated part and the uncoated skin part is small.
  • a resin solution is cast and dried on the surface of a cast peelable substrate having an inverted pattern, and the dried product is peeled off from the substrate to obtain a film M as a material of the film layer 4a.
  • the inverted pattern is transferred to form irregularities.
  • the monomers that are the raw materials for the adhesive are mixed and dissolved in ethyl acetate, added with a polymerization initiator, copolymerized, and then added with a crosslinking agent.
  • a casting solution is prepared using the commercially available silicone type adhesive which is the system etc. which mix a predetermined two types of solution.
  • a rubber adhesive is used as the material for the adhesive layer 6a
  • the polymer that is the raw material of the adhesive is mixed and dissolved in toluene, a softener, a tackifier, and an antioxidant are added, and a casting solution is prepared.
  • a urethane-based adhesive is used as the material for the adhesive layer 6a
  • a predetermined two types of solutions are mixed immediately before casting to prepare a casting solution.
  • any of acrylic, silicone, rubber or urethane adhesives cast the casting solution onto a release sheet and dry or heat the cast.
  • the adhesive sheet N used as the raw material of the adhesive layer 6a is obtained.
  • One surface of the film M (the surface that is not the transfer surface) is placed on and bonded to the surface of the adhesive sheet N that does not have a release sheet, to obtain a laminate of M, N, and the release sheet.
  • this laminate is punched into a predetermined shape from the other side (transfer surface) side of M with a blade shape, the skin contact surface 16 of the skin masking material (2a, 2b) is covered with a piece of release sheet (release paper) The obtained form is obtained.
  • the skin masking material (2a, 2b) is distributed as a product with the skin contact surface 16 covered with the release paper, and the release paper is peeled off immediately before being applied to the skin by the user.
  • the other surface (10a, 10b) of the skin masking material (2a, 2b) is used. The formed uneven shape can be adjusted.
  • the skin masking material (2a, 2b) is the total light transmission of the film layer 4a obtained by measuring with an integrating sphere light transmittance measuring device in the plastic optical property test method in accordance with JIS K 7105: 1981. It is preferable that fine particles are contained in the film layer 4a so that the rate is 75 to 90%. Further, the skin masking material (2a, 2b) is a parallel of the film layer 4a obtained by measuring using an integrating sphere light transmittance measuring device in the plastic optical property test method in accordance with JIS K 7105: 1981.
  • the film layer 4a should contain fine particles dispersed so that the light transmittance is 0 to 12% and the haze (cloudiness value) of the film layer 4a is 84 to 100%. good.
  • the total light transmittance of the film layer 4a is 75 to 90%, a part of the incident light to the film layer 4a is absorbed by the fine particles.
  • the parallel light transmittance of the film layer 4a is 0 to 12% and the haze (haze value) of the film layer 4a is 84 to 100%, most of the incident light to the film layer 4a is the film. It diffuses by irregular reflection on the surface of the fine particles dispersed in the layer 4a. Due to these actions, when the skin masking material (2a, 2b) is affixed to a different part of the skin, the extraneous part is not visible through the skin masking material (2a, 2b). You can hide and hide. Furthermore, no shine occurs on the other side (10a, 10b). In this case, the skin masking materials (2a, 2b) are preferable in terms of appearance because the difference from other parts of the skin is difficult to understand when cosmetics are further applied thereon.
  • the portion to be concealed will be seen through the skin masking material (2a, 2b). Even when the parallel light transmittance of the film layer 4a exceeds 12% or when the haze (cloudiness value) of the film layer 4a is less than 84%, the portion to be concealed can be seen through. Further, if the total light transmittance of the film layer 4a is less than 75%, the skin masking material (2a, 2b) is hardly reflected in the portion where the skin masking material (2a, 2b) is applied. The appearance does not fit into the surrounding skin. After the foundation is further applied from above the skin masking material (2a, 2b), the part where the skin masking material (2a, 2b) is applied to the surrounding skin becomes unnatural and becomes conspicuous.
  • the particle size p of the fine particles contained in the film layer 4a is preferably 10 nm ⁇ p ⁇ 20 ⁇ m and p ⁇ (w / 2).
  • the content of the fine particles is such that when the film as the material of the film layer 4a is produced, the total light transmittance is 75 to 90% and the parallel light transmittance is 0% to 12%.
  • haze cloudiness value
  • the content of the fine particles is preferably 0.05 to 30% by weight with respect to the film weight.
  • Substances constituting the fine particles include pearl pigments, talc, mica, silica, kaolin, clay, mica powder, quartz powder, diatomaceous earth, montmorillonite, vermiculite, amorphous silica, silica-alumina, carbon black, ferrite, graphite, Examples thereof include resin powders, oxalates such as calcium, magnesium, aluminum, lithium, barium, and titanium, sulfates, carbonates, phosphates, aluminates, and metal oxides. These fine particles absorb the light incident on the film layer 4a or diffuse it by irregular reflection. These fine particles are substances that are not harmful to the skin and the like.
  • the fine particles are preferably made of a chemically stable substance.
  • the film used as the material of the film layer 4a has a total light transmittance of 75 to 90% because the unevenness formed on the other surface (10a, 10b) refracts incident light on the film in addition to the action of fine particles.
  • the parallel light transmittance is 0 to 12%, and the haze (haze value) is 84 to 100%.
  • the object is within a distance of about 1 cm from the film, the shape and brightness of the object Although it can be recognized, it can exhibit transparency such that the shape, brightness, etc. of an object farther than about 1 cm from the film cannot be recognized.
  • the film used as the material of the film layer 4a may be a film to which a dye or pigment is added in addition to the fine particles.
  • a dye or pigment is added in addition to the fine particles.
  • the color tone of the film layer 4a can be adjusted so as to easily match the hue of the skin.
  • the skin masking material (2a, 2b) is applied to the skin and cosmetics are further applied, the applied color is corrected by makeup so that the applied site cannot be distinguished from other parts of the skin. Can be reduced.
  • the moisture permeability of the skin masking material (2a, 2b) is preferably 400 g / (m 2 ⁇ day) or more. Since water vapor of about 300 g / (m 2 ⁇ day) radiates from the surface of the skin on a daily basis, if a film with low moisture permeability is applied to the skin, the skin may become stuffy and normal bacteria on the skin may grow and cause inflammation There is. On the other hand, when the moisture permeability of the skin masking material (2a, 2b) is 400 g / (m 2 ⁇ day) or more, the water vapor emitted from the skin surface passes through the skin masking material (2a, 2b). In this case, when the skin masking material (2a, 2b) is affixed to the skin, it is possible to avoid stuffiness of the skin and skin damage that may occur due to stuffiness.
  • the moisture permeability of the skin masking material (2a, 2b) is more preferably 900 to 5,000 g / (m 2 ⁇ day).
  • the moisture permeability is 900 g / (m 2 ⁇ day) or more
  • the skin masking material (2a, 2b) is affixed, the feeling of stuffy skin can be almost eliminated.
  • the moisture permeability is 5,000 g / (m 2 ⁇ day) or less
  • the skin masking material (2a, 2b) swells when water, sweat or alcohol is absorbed by the skin masking material (2a, 2b). It can be avoided that it stretches easily and exfoliates easily.
  • the moisture permeability is 900 to 5,000 g / (m 2 ⁇ day)
  • the skin masking material (2a, 2b) is affixed to the wound, the wound surface is maintained in a moist state, and is created by moist therapy. Can be treated quickly.
  • the moisture permeability of the skin masking material (2a, 2b) is more preferably 1,000 to 3,000 g / (m 2 ⁇ day).
  • the moisture permeability of the skin masking material (2a, 2b) is affected by the material, shape and thickness of the film layer 4a.
  • a material of the film layer 4a it is preferable to use a film having a moisture permeability of 1,000 g / (m 2 ⁇ day) or more when the thickness is 30 ⁇ m.
  • a material with high moisture permeability is used for the film layer 4a, even when the thickness w of the film layer 4a is increased, the feeling of stuffy skin can be almost eliminated when the skin masking material (2a, 2b) is applied. .
  • the moisture permeability of the skin masking material (2a, 2b) is also affected by the size of Rz on the other surface (10a, 10b). If the skin masking material (2a, 2b) uses a film in which many deep micropores are formed on the other surface (10a, 10b) as a material, the film layer 4a exhibits high moisture permeability. Further, in the skin masking material (2a, 2b), the ratio of the unevenness formed on the other surface (10a, 10b) to the thickness w of the film layer 4a may be very large. is there. In this case, even if a film with low moisture permeability is used as the material of the film layer 4a or a thick film is used, the film layer 4a can exhibit high moisture permeability.
  • the skin masking material (2a, 2b) has a particularly high permeability when the distance from the bottom of the concave portion of the unevenness formed on the other surface (10a, 10b) to the one surface 12 of the film layer 4a is 30 ⁇ m or less. Can indicate humidity. That is, when the thickness w of the film layer 4a is 0 ⁇ m ⁇ w ⁇ 30 ⁇ m, the moisture permeability is particularly high regardless of the value of Rz. Further, when 30 ⁇ m ⁇ w, a particularly high moisture permeability can be exhibited if (w ⁇ 30 ⁇ m) ⁇ Rz ⁇ w.
  • the moisture permeability of the film layer 4a is measured by a cup method according to JIS Z 0208.
  • calcium chloride is used as the hygroscopic agent
  • paraffin having a melting point of 52 to 54 ° C. that is commercially available as a reagent is used as the sealant.
  • the cup containing the hygroscopic agent is placed in a constant temperature and humidity chamber having a temperature of 40 ° C. and a humidity of 90% RH, and the weight of the entire cup is measured three times every 1.5 hours from the start of measurement.
  • the value of moisture permeability is obtained from the average value of the second and third measurements.
  • the pressure-sensitive adhesive layer 6a preferably contains 10 to 50% by weight of an organic compound having a polar group that is liquid at room temperature.
  • the normal temperature here is 5 to 35 ° C. If the organic compound having a polar group, which is liquid at room temperature, is less than 10% by weight with respect to the pressure-sensitive adhesive layer 6a, the pressure-sensitive adhesive layer 6a does not become a gel depending on the composition of the pressure-sensitive adhesive. Moreover, when it exceeds 50 weight% with respect to the adhesive layer 6a, depending on a composition of an adhesive, a gel body may not be formed with the adhesive layer 6a, and there exists a possibility that the adhesive force of the adhesive layer 6a may become inadequate.
  • the polar group is a functional group having polarity such as an amide group, amino group, aldehyde group, ether group, ester group, carboxyl group, keto group, sulfo group, hydroxyl group, and phosphate group.
  • Organic compounds having polar groups that are liquid at room temperature include fatty acid esters, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene sorbit fatty acid esters, polyoxyethylene alkyl ethers, polyoxyethylene hydrogenated castor oil, glycerin.
  • fatty acid esters Selected from the group consisting of fatty acid esters, polyglycerin fatty acid esters, polyoxyethylene glycerin fatty acid esters, fatty acids, aliphatic alcohols, phospholipids, polyhydric alcohols such as 1,3-butylene glycol, glycerin, polyethylene glycol, and mixtures thereof. And organic compounds.
  • the pressure-sensitive adhesive layer 6a contains 10 to 50% by weight of an organic compound having a polar group that is liquid at room temperature, the pressure-sensitive adhesive layer 6a becomes a gel, so that the skin masking material (2a, 2b) Relieve stress caused by expansion and contraction.
  • the organic compound is a hydrophilic substance or a highly polar substance, the skin masking material (2a, 2b) exhibits high moisture permeability through the adhesive layer 6a. For this reason, skin masking material (2a, 2b) suppresses a rash in the skin of the site
  • the skin masking material (2a, 2b) when the skin masking material (2a, 2b) is peeled from the skin, irritation to the skin is reduced to prevent keratin damage.
  • the pressure-sensitive adhesive layer 6a is in the form of gel and the moisture permeability of the skin masking material (2a, 2b) is 900 to 5,000 g / (m 2 ⁇ day), the skin masking material (2a, 2b) is used as a wound, etc.
  • the extraneous part is maintained in a wet state, and early healing of the foreign part is observed.
  • the organic compound contained in the pressure-sensitive adhesive layer 6a may be a hydrocarbon compound selected from the group consisting of hydrocarbon compounds such as squalane, squalene, polybutene, polyisobutylene, and mixtures thereof.
  • hydrocarbon compounds such as squalane, squalene, polybutene, polyisobutylene, and mixtures thereof.
  • One or more types of surfactant may be sufficient as the organic compound contained in the adhesive layer 6a.
  • ointments and creams for the treatment of acne have been marketed in order to treat different parts of the skin such as acne, wounds and scars.
  • it has been considered to avoid applying an ointment or the like to an extraordinary portion and covering it with a cosmetic.
  • the adhesive layer 6a may contain a medicinal component for the skin.
  • the skin masking material (2a, 2b) when the skin masking material (2a, 2b) is applied to a foreign part of the skin, the part can be recovered and healed.
  • the medicinal component has a function of dissolving sebum etc. that closes the secretory glands and sweat glands and has an antibacterial effect
  • the skin masking material (2a, 2b) is applied to the skin disease part such as acne or pimple, Can be treated while hiding the part.
  • the pressure-sensitive adhesive layer 6a contains a fatty acid ester or the like, the medicinal component can be dissolved in the fatty acid ester or the like to exert the above-described therapeutic effect.
  • the skin masking material (2a, 2b) is applied to a different part of the skin such as acne, pimple, wound, etc. This can not only make the difference difficult to understand, but at the same time, it can be used to treat heterogeneous parts.
  • the medicinal component is added to and mixed with the cast solution before casting in the above-described method for producing the skin masking material (2a, 2b), and the cast solution after mixing Is cast on a release sheet.
  • the skin masking material (2a, 2b) containing the medicinal component in the adhesive layer 6a can be obtained.
  • ⁇ -hydroxy acids, salicylic acid examples of the medicinal component include compounds selected from the group consisting of ⁇ -hydroxy acids, salicylic acid, and mixtures thereof.
  • ⁇ -hydroxy acids include lactic acid, citric acid, glycolic acid, malic acid, succinic acid and the like. Since these components have effects such as keratin softening and pore expansion, the skin masking material (2a, 2b) can be used for the treatment of skin diseases when included in the adhesive layer 6a. Moreover, since these components are acidic, when used for the treatment of skin wounds, the growth of skin resident bacteria can be suppressed to improve wound healing.
  • ⁇ -hydroxy acids and salicylic acid are preferably added in an amount of 0.1 to 10% by weight based on the pressure-sensitive adhesive layer 6a.
  • antibacterial agent An antibacterial agent is mentioned as a medicinal component.
  • the antibacterial agent is preferably added so as to be 0.01 to 20% by weight with respect to the pressure-sensitive adhesive layer 6a. With this configuration, the antibacterial action and the bactericidal action are exhibited at the site where the skin masking material (2a, 2b) is affixed, and the growth of bacteria is suppressed.
  • the antibacterial agent is more preferably added in an amount of 0.05 to 5% by weight with respect to the pressure-sensitive adhesive layer 6a.
  • antibacterial agent examples include compounds selected from the group consisting of isopropylmethylphenol, silver-based antibacterial agents, and mixtures thereof.
  • Isopropylmethylphenol is 3-methyl-4-isopropylphenol.
  • silver-based antibacterial agent examples include compounds selected from the group consisting of silver colloids, silver inclusions such as silver zeolite, silver-based compounds, and mixtures thereof.
  • These antibacterial agents exhibit high antibacterial properties and safety, have almost no skin irritation, and can be used as additives for quasi drugs and cosmetics.
  • the skin masking material (2a, 2b) can be easily used in various scenes of daily life.
  • Antibacterial agents include kanamycin sulfate, gentamicin sulfate, fradiomycin sulfate, erythromycin, tetracycline hydrochloride, oxytetracycline hydrochloride, demethylchlortetracycline hydrochloride, chloramphenicol, bacitracin, sodium fusidate, sulfadiazine Examples thereof include compounds selected from the group consisting of antibacterial agents such as silver and mixtures thereof. These antibacterial agents are conventionally used in pharmaceuticals in the form of ointments, patches and the like. When these antibacterial agents are included in the pressure-sensitive adhesive layer 6a, the skin masking material (2a, 2b) can be used as a pharmaceutical product for the skin.
  • Anti-inflammatory drugs examples include anti-inflammatory drugs.
  • Anti-inflammatory drugs include indomethacin, piroxicam, felbinac, loxoprofen sodium, diclofenac sodium, ketoprofen, flurbiprofen, ibuprofen piconol, ibuprofen, flufenamic acid, suprofen, bufexamac, bendazac, ufenamate, glycyrrhizic acid or its derivatives
  • the combination of the anti-inflammatory drug ibuprofen piconol and the antibacterial agent isopropylmethylphenol is preferred.
  • Other medicinal ingredients include sodium cromoglycate, tranilast, ketotifen fumarate, azelastine hydrochloride, oxatomide, mequitazine, fexofenadine hydrochloride, epinastine hydrochloride, ebastine, cetirizine hydrochloride, bepotastine besylate, Examples include compounds selected from the group consisting of antiallergic drugs such as olopatadine hydrochloride, loratadine and suplatast tosylate, and mixtures thereof.
  • Medicinal ingredients include azulene, sulfadiazine, alcloxa, lysozyme hydrochloride, tretinoin tocopheryl, bucladecin sodium, alprostadil alphadex, trafermin (genetical recombination), and a mixture of these Examples include compounds selected from the group. These pharmaceuticals are conventionally used as dermatological agents.
  • the medicinal properties include antipruritic drugs such as crotamiton, atopic dermatitis drugs such as tacrolimus hydrate, vitiligo drugs such as methoxalene, pregnanediol, nadifloxacin, clindamycin phosphate, adapalene and other acne treatments
  • Drugs etretinate, tacalcitol hydrate, calcipotriol, maxacalcitol, vitamin A, urea, cyclosporine and other keratosis / psoriasis treatments, salicylic acid and other emollients, carpronium chloride, finasteride and other hair loss treatments
  • Group consisting of drugs, therapeutic drugs for leprosy such as diphenylsulfone, clofazimine, rifampicin, ofloxacin
  • blood circulation promoting / skin moisturizers such as heparin sodium and heparin-like substances
  • Examples of the medicinal ingredients include compounds selected from the group consisting of vitamin C and derivatives thereof, vitamin E and derivatives thereof, peony extract, toki extract, sicon extract, sulfur, nordihydroguaiaretic acid, and mixtures thereof.
  • Examples of the medicinal component include sulfate polysaccharides such as hyaluronic acid, polyhydric alcohols such as glycerin, butylene glycol, polyethylene glycol, and the like, which are considered to have a moisturizing effect, and compounds selected from the group consisting of these.
  • the medicinal component may contain one or more medicinal plant extracts.
  • the medicinal ingredients include hair-growth agents, blood circulation promoters, stimulants, hormones, anti-wrinkle agents, anti-aging agents, squeeze agents, cooling sensation agents, warming sensation agents, wound treatment promoters, stimulation mitigation agents, cell activators, It may be a plant / animal / microbe extract, antipruritic agent, exfoliating / dissolving agent, antiperspirant, refreshing agent, astringent and the like.
  • the medicinal component may contain one or more active pharmaceutical ingredients such as thymol, for example.
  • the pressure-sensitive adhesive layer 6a may contain a disinfectant.
  • a disinfectant a compound selected from the group consisting of iodine substances such as ethanol, isopropanol, povidone iodine, benzethonium chloride, benzalkonium chloride, chlorhexidine gluconate, alkyldiaminoethylglycine, and mixtures thereof. Can be mentioned. These disinfectants are conventionally used for disinfecting fingers and skin.
  • the pressure-sensitive adhesive layer 6a may contain a compound selected from the group consisting of antioxidants such as dibutylhydroxytoluene and butylhydroxyanisole, and mixtures thereof.
  • the material of the film layer 4a is preferably a polyether polyurethane (EU) or polyester polyurethane film.
  • EU polyether polyurethane
  • the film layer 4a has high stretchability and high moisture permeability.
  • the skin masking material (2a, 2b) fits the skin when applied.
  • cosmetics such as a foundation and a concealer are further applied from above, the powder held in the recesses formed on the other surface (10a, 10b) is moistened with water vapor emanating from the skin surface, and its viscosity increases. For this reason, it becomes easier to hold
  • the polyether polyurethane (EU) or polyester polyurethane film has a moisture permeability of 950 g / (m 2 ⁇ day) or more when the surface is smooth and the thickness is 30 ⁇ m. Moreover, since polyether polyurethane (EU) and polyester polyurethane are materials having polar groups, the other surfaces (10a, 10b) can be colored with a water-soluble dye.
  • the thickness w of the film layer 4a is preferably 6 ⁇ m ⁇ w ⁇ 100 ⁇ m.
  • w is less than 6 ⁇ m, the strength of the film layer 4a is insufficient.
  • w exceeds 100 ⁇ m, the tensile elastic modulus of the film layer 4a becomes excessive, and the skin masking materials (2a, 2b) do not fit the curved surface of the skin. Moreover, since the skin masking material (2a, 2b) does not follow the expansion and contraction of the skin, the user may feel uncomfortable.
  • the thickness w of the film layer 4a is more preferably 10 ⁇ m ⁇ w ⁇ 60 ⁇ m. Since recesses are formed on the other surfaces (10a, 10b), if w is 6 ⁇ m ⁇ w ⁇ 10 ⁇ m, the strength of the film layer 4a may not be sufficient. Also, if w is 60 ⁇ m ⁇ w ⁇ 100 ⁇ m, depending on the film used as the material of the film layer 4a, the moisture permeability of the skin masking material (2a, 2b) does not exceed 900 g / (m 2 ⁇ day). There is a risk that the person may feel skin stuffiness.
  • the skin masking material 2f shown in FIG. 2 is a composite film 38 in which the material of the film layer 4f is a laminate of an uneven urethane film 34 and a hydrophobic film 36.
  • the material of the hydrophobic film 36 include hydrophobic synthetic resins selected from the group consisting of polyolefin resins, thermoplastic elastomers, rubber resins, and mixtures thereof.
  • examples of the thermoplastic elastomer include a styrene isoprene styrene block copolymer, a styrene butadiene copolymer, and modified products thereof such as acrylic.
  • the rubber resin examples include isoprene rubber, butyl rubber, polyisobutylene, and modified products thereof.
  • the composite film 38 is formed by casting a urethane resin solution on the surface of a substrate having an uneven pattern on the surface and drying it to form a film, and further using a resin solution that is a raw material for the hydrophobic film 36. It can be obtained by peeling a laminate in which a thin film is formed on a film from a substrate.
  • the film layer 4f is a urethane film 34 having irregularities formed by transferring an inverted pattern on the surface of the substrate on the other surface 10f side, and a hydrophobic film 36 on the one surface 12 side thereof.
  • the thickness v of the hydrophobic film 36 is 2 ⁇ m ⁇ v ⁇ 10 ⁇ m, and v ⁇ (w / 2), and Rz of the other surface 10f is Rz ⁇ (w ⁇ 1 ⁇ m). It is preferable that the unevenness to be formed is formed.
  • the hydrophobic film 36 is as thin as 2 ⁇ m ⁇ w ⁇ 10 ⁇ m, the decrease in the water vapor transmission rate of the film layer 4f is minimized.
  • the recess formed in the other surface 10f may be a through-hole penetrating the urethane film 34, but it is hydrophobic. It does not become a through-hole penetrating to the film 36.
  • the hydrophobic film 36 prevents permeation of the medicinal component, the medicinal component contained in the pressure-sensitive adhesive layer 6 a does not migrate to the urethane film 34. For this reason, in the skin masking material 2f using the composite film 38 as the material of the film layer 4f, the medicinal components are efficiently released to the skin while maintaining a moisture permeability of 400 g / (m 2 ⁇ day) or more.
  • the skin masking material 2g shown in FIG. 3 is a composite film 44 in which a film layer 4g is formed by laminating an uneven film 40 and a red film 42.
  • the color of the concavo-convex film 40 is a color selected from the group consisting of colorless and transparent, milky white and translucent, and colors between these colors.
  • the composite film 44 is formed by casting a resin solution, which is a raw material of the film 40 having unevenness, onto the surface of a substrate having an uneven pattern on the surface and drying, and further, the raw material of the red film 42 on the dried resin. The obtained resin solution is cast, and the dried laminate is peeled off from the substrate.
  • the composite film 44 When the composite film 44 is manufactured, pigment, titanium oxide, talc, silica, and the like are added as fine particles to the resin solution that is the raw material of the uneven film 40, and silicone oil is further added. By adding fine particles, the film 40 having irregularities becomes colorless and transparent, milky white and translucent, or a color between these colors. By adding silicone oil, the composite film 44 can be easily peeled off from the substrate. Moreover, resin with a low elastic modulus is used for the resin solution used as the raw material of the red film 42, and further fine particles are added. By using a resin having a low elastic modulus, the red film 42 becomes soft. The resin solution that is the raw material of the red film 42 is light red, but the red film 42 becomes light red by adding fine particles.
  • the other surface 10g side is a film 40 having irregularities formed by transferring an inverted pattern on the surface of the substrate, and one surface 12 side thereof is a red film 42.
  • the composition of the composite film 44 is similar to that of the human skin. That is, since the epidermis, which is the outermost layer of the skin, does not have capillaries, it is colorless and transparent, milky white and translucent, or a color between these colors. The unevenness formed in the stratum corneum of the epidermis refracts incident light on the skin or diffuses it by irregular reflection. Melanin or the like in the basal layer of the epidermis absorbs light incident on the skin. Furthermore, the dermis inside the epidermis is light red because it has capillaries, and the proteoglycan held in the extracellular matrix is soft and soft because it contains water.
  • the composite film 44 By making the composite film 44 resemble the skin, when the skin masking material 2g is affixed to the skin, the appearance becomes indistinguishable from other parts of the skin, and the extraneous parts of the skin are hidden so that they are less noticeable. can do.
  • the skin masking material 2h shown in FIG. 4 includes an adhesive protecting portion 18 that is laminated and laminated on the skin contact surface 16 of the adhesive layer 6a.
  • the adhesive protecting portion 18 include a film such as a rigid polyethylene terephthalate, and a release paper 19 made of paper that has been subjected to silicone treatment. With this configuration, the skin contact surface 16 is protected until the adhesive protecting part 18 is peeled off immediately before the user sticks. Moreover, since the adhesive protection part 18 functions as a support body, the handling of the skin masking material 2h becomes easy at the time of manufacture or when the user carries it.
  • the release paper 19 is provided with a cut 20.
  • the pressure-sensitive adhesive protection unit 18 includes two release papers 19 divided by a cut 20.
  • the pressure-sensitive adhesive protection unit 18 includes a folded portion 22 in which the release paper 19 is folded at the cut 20, and a knob portion 23 in which the release paper 19 is further superimposed on the folded portion 22. The user can easily peel off the release paper 19 by picking the folded portion 22 or the knob portion 23 with the fingertip.
  • the skin masking material 2h includes a concavo-convex protective portion 24 laminated on the other surface (10a, 10b) of the film layer 4a.
  • the unevenness protector 24 is provided with a rigid plastic film 25 and a weak adhesive layer 26 formed by thinly applying an adhesive to one side of the plastic film 25. Since the unevenness protection part 24 functions as a support during manufacture, the deformation of the laminate 14 is suppressed in the process of laminating the adhesive protection part 18 on the skin contact surface 16 to facilitate manufacture. Further, the other surface (10a, 10b) is protected until the user peels off the unevenness protecting portion 24. When sticking to the skin, it can be avoided that the laminate 14 hangs down and the skin contact surfaces 16 adhere to each other, or that the laminate 14 is stuck with wrinkles.
  • the plastic film 25 and the weak pressure-sensitive adhesive layer 26 provided on the unevenness protection part 24 have a cut 28.
  • the unevenness protector 24 is provided with two plastic films 25 and a weak adhesive layer 26 divided by a cut 28.
  • the unevenness protector 24 is provided with a knob 29 that is superimposed on the cut 28.
  • the knob 29 of the unevenness protector 24 includes a film 30 and an adhesive layer 31 formed by applying an adhesive to a part of one side of the film 30.
  • the pressure-sensitive adhesive layer 31 of the knob portion 29 is laminated so as to adhere to the plastic film 25 on both sides of the cut 28.
  • the composition and application amount of the pressure-sensitive adhesive are adjusted so that the pressure-sensitive adhesive layer 31 of the knob 29 has stronger adhesive strength than the weak pressure-sensitive adhesive layer 26.
  • the shape of the film 30 of the knob 29, the shape of the adhesive layer 31 of the knob 29, the position where the adhesive layer 31 is laminated with the plastic film 25 on both sides of the cut 28, the film 30 of the knob 29, etc. Is not limited to that illustrated in
  • the film 30 of the knob part 29 is removed.
  • the plastic film 25 and the slightly adhesive layer 26 are also pulled and deformed.
  • corrugated protection part 24 has the cut
  • the entire unevenness protector 24 can be easily peeled off based on the sense of touch of the fingertip without the user looking at the mirror.
  • the cut 20 of the adhesive protecting part 18 and the cut 28 of the unevenness protecting part 24 are provided at positions where they do not overlap.
  • the cut of the adhesive protection part 18 is provided at the end of the skin contact surface 16 of the adhesive layer 6, and the cut 28 of the unevenness protection part 24 is provided at the center of the other surface 10 of the film layer 4.
  • the skin masking material 2h is unexpectedly bent and the adhesive protecting part 18 and the unevenness protecting part 24 are prevented from being detached. be able to.
  • it can avoid handling by making the direction of the other surface (10a, 10b) of the film layer 4a and the skin contact surface 16 of the adhesive layer 6a reverse.
  • the skin masking material 2i shown in FIG. 5A is provided with a portion 33i where the adhesive layer 6i is not laminated at the center of the one surface 12 of the film layer 4a, and the adhesive layer 6i is laminated at the peripheral portion of the one surface 12. .
  • the adhesive layer 6i is laminated
  • the skin masking material 2i has a high moisture permeability because there is no adhesive layer 6i at the portion 33i.
  • the portion 33i since the portion 33i is present after the skin masking material 2i is applied, the film layer 4a can be prevented from turning up by the adhesive layer 6i laminated on the peripheral portion of the one surface 12.
  • the portion 33i may be fitted with a non-sticky holding material.
  • the holding material preferably contains a medicinal component.
  • the skin masking material 2j shown in FIGS. 5 (b) and 5 (c) is provided with a portion 33j where the adhesive layer 6j is not laminated and a lattice-like adhesive layer 32 at the center of the surface 12, and the peripheral portion of the surface 12 A pressure-sensitive adhesive layer 6j is laminated on the substrate.
  • the adhesive layer (6j, 32) is laminated
  • the skin masking material 2j can prevent the central portion of the film layer 4a from being lifted by the lattice-shaped adhesive layer 32 after being attached to the skin, in addition to the same effects as the skin masking material 2i.
  • an adhesive layer (6i , 6j, 32) may be screen-printed on one surface of the film M.
  • the skin masking material (2a, 2b, 2f, 2g, 2i, 2j) shown in FIGS. 1 to 3 and 5 has the adhesive protecting part 18 and the unevenness protecting part 24 like the skin masking material 2h shown in FIG. You may prepare.
  • the skin masking materials (2a, 2b, 2f, 2g, 2h) shown in FIGS. 1 to 4 are laminated with adhesive layers (6i, 6j) like the skin masking materials (2i, 2j) shown in FIG. You may provide the part (33i, 33j) which is not performed, and the grid
  • Example 1 As a peelable substrate for casting, a substrate having a surface-inverted inverted pattern of artificial leather on the surface was prepared. Rz of the surface of this substrate was 10 ⁇ m. Moreover, Leocoat U-6285M (solid content 30% by weight) (manufactured by Toray Cortex Co., Ltd.) was prepared as a urethane resin solution. As fine particles, 2.5 parts by weight of silica powder having an average particle diameter of 4 ⁇ m, 0.2 parts by weight of a red pigment, 0.15 parts by weight of titanium oxide, and 10 parts by weight of synthetic mica were prepared. A solution in which these fine particles were added and dispersed in a mixed solution of polyethylene glycol, ethyl acetate and an emulsifier was prepared, and this solution was mixed with 87 parts by weight of a urethane resin solution.
  • a urethane resin solution mixed with fine particles was cast on the surface of the substrate and dried, and the dried product was peeled from the substrate to obtain a support S. Since the solvent such as ethyl acetate is vaporized in the process of drying the urethane resin solution, substantially no solvent remains on the support S obtained after drying.
  • the thickness of the film of the support F was 30 ⁇ m.
  • a reverse pattern was transferred to the other surface (transfer surface) of the film of the support S, and Rz on the other surface was 10 ⁇ m.
  • a plurality of holes having a depth of 5 to 10 ⁇ m and a diameter of 5 to 20 ⁇ m and a plurality of grooves having a depth of 5 to 25 ⁇ m and a width of 5 to 25 ⁇ m were formed.
  • one surface (the surface that is not the transfer surface) of the support S was smooth because it was not in contact with the casting peelable substrate.
  • the main component liquid of the acrylic pressure-sensitive adhesive is 2-ethylhexyl acrylate (2-EHA), methoxyethyl acrylate (MEA), and acrylic acid (AA) in a weight ratio of 68: 25: 7 to ethyl acetate.
  • 2-EHA 2-ethylhexyl acrylate
  • MEA methoxyethyl acrylate
  • AA acrylic acid
  • 0.3 part by weight of a polymerization initiator azobisisobutyronitrile (AIBN) was added and copolymerized at 60 to 65 ° C. to prepare a solution containing an adhesive polymer compound.
  • AIBN polymerization initiator azobisisobutyronitrile
  • One surface of the film of the support S (the surface that is not the transfer surface) was placed on the surface of the pressure-sensitive adhesive sheet T on which the release sheet was not attached to obtain a laminate of S, T, and the release sheet.
  • the release sheet was peeled off from the laminate and replaced with release paper provided with a cut line, a folded portion and a knob.
  • a plastic film laminated with a thin adhesive layer is applied to the other side (transfer surface) of S, and a cut is made in the plastic film and weak adhesive layer by half-cut processing so that the S film is not damaged. I put it in.
  • a laminate of the plastic film, S, T, and release paper was punched into a 15 mm diameter circle from the side where the plastic film was applied. The resulting 15 mm diameter circular laminate was used as a skin masking material sample.
  • the reverse pattern was transferred to the other surface (transfer surface) of the film, and the Rz of the other surface of the film was 6 ⁇ m.
  • the other surface On the other surface, a plurality of holes having a depth of 3 to 7 ⁇ m and a diameter of 3 to 20 ⁇ m and a plurality of grooves having a depth of 3 to 12 ⁇ m and a width of 3 to 25 ⁇ m were formed.
  • the reverse pattern was transferred to the other surface (transfer surface) of the film.
  • Rz was 18 ⁇ m and Ra was 9 ⁇ m.
  • a plurality of holes having a depth of 5 to 18 ⁇ m and a diameter of 5 to 20 ⁇ m and a plurality of grooves having a depth of 5 to 15 ⁇ m and a width of 5 to 15 ⁇ m were formed.
  • Example 4 175 parts by weight of the main component liquid of the acrylic adhesive prepared in Example 1, 30 parts by weight of sorbitan monooleate, 0.07 parts by weight of dibutylhydroxytoluene (BHT) as an antioxidant, 2.1 parts by weight of lactic acid And 3.5 parts by weight of an isocyanate-based crosslinking agent solution (solid content: about 60% by weight) were added to prepare a casting solution. About the others, the sample of the skin masking material of Example 4 was prepared on the same conditions as Example 1. FIG.
  • Example 5 In preparing the pressure-sensitive adhesive in Example 1, the main component liquid of the acrylic pressure-sensitive adhesive was 2-ethylhexyl acrylate (2-EHA), methoxyethyl acrylate (MEA), and hydroxyethyl acrylamide (HEAA) in a weight ratio. The mixture was dissolved in ethyl acetate at a ratio of 68: 25: 7, 0.3 parts by weight of a polymerization initiator azobisisobutyronitrile (AIBN) was added, and the mixture was copolymerized at 60 to 65 ° C. A solution containing an adhesive polymer compound was prepared.
  • 2-EHA 2-ethylhexyl acrylate
  • MEA methoxyethyl acrylate
  • HEAA hydroxyethyl acrylamide
  • the solid content of the adhesive polymer compound produced by copolymerization accounted for 40% by weight.
  • 175 parts by weight of the main component liquid, 30 parts by weight of sorbitan monooleate, 0.07 parts by weight of dibutylhydroxytoluene (BHT) as an antioxidant, and an isocyanate-based crosslinking agent solution (solid content of about 60) for curing The casting solution was prepared by adding 1.4 parts by weight. The casting solution was cast on a release sheet and dried to obtain an adhesive sheet U. About the others, the sample of the skin masking material of Example 5 was prepared on the same conditions as Example 1.
  • Example 6 When the film was prepared in Example 4, a substrate having a surface Rz of 25 ⁇ m was used as the peelable substrate for casting. For this reason, in the film prepared in Example 6, the Rz of the other surface (transfer surface) was 25 ⁇ m. Moreover, when preparing the casting solution in Example 4, 2.1 parts by weight of salicylic acid was added instead of 2.1 parts by weight of lactic acid. About the others, the sample of the skin masking material of Example 6 was prepared on the same conditions as Example 4.
  • Example 7 When preparing the casting solution in Example 6, 2.1 parts by weight of glycolic acid was added instead of 2.1 parts by weight of salicylic acid, and 0.2 parts by weight of isopropylmethylphenol was further added as an antibacterial agent. About the others, the sample of the skin masking material of Example 7 was prepared on the same conditions as Example 6.
  • Example 8 When preparing the film in Example 1, a substrate having a surface Rz of 25 ⁇ m was used as the peelable substrate for casting. In the film prepared in Example 8, the Rz of the other surface (transfer surface) was 25 ⁇ m.
  • the main component liquid of the acrylic resin adhesive is 2-ethylhexyl acrylate (2-EHA), vinyl acetate (VA), and hydroxyethyl acrylate (HEA) at a weight ratio of ethyl acetate of 68: 25: 7. Then, 0.3 wt% of a polymerization initiator azobisisobutyronitrile (AIBN) was added and copolymerized at 60 to 65 ° C. to prepare a solution containing an adhesive polymer compound. In this main component liquid, the solid content of the adhesive polymer compound produced by copolymerization accounted for 40% by weight.
  • 2-EHA 2-ethylhexyl acrylate
  • VA vinyl acetate
  • HOA hydroxyethyl acrylate
  • AIBN polymerization initiator azobisisobutyronitrile
  • Example 9 When preparing the casting solution in Example 8, 175 parts by weight of the composition solution, 3.5 parts by weight of ibuprofenpiconol as an anti-inflammatory agent, 0.2 parts by weight of isopropylmethylphenol as an antibacterial agent, monooleic acid 3.5 parts by weight of sorbitan ester, 7 parts by weight of isopropyl myristate (IPM), 3.5 parts by weight of butanediol, 7 parts by weight of lactic acid, 0.07 parts by weight of dibutylhydroxytoluene (BHT) as an antioxidant, and Therefore, 1.3 parts by weight of an isocyanate-based crosslinking agent solution (solid content: about 60% by weight) was added to prepare a casting solution. About the others, the sample of the skin masking material of Example 9 was prepared on the same conditions as Example 8.
  • IPM isopropyl myristate
  • BHT dibutylhydroxytoluene
  • Example 10 When preparing the film in Example 1, a substrate having a surface Rz of 25 ⁇ m was used as the peelable substrate for casting. In the film prepared in Example 10, Rz on the other surface (transfer surface) was 25 ⁇ m.
  • Example 1 When preparing the casting solution in Example 1, 175 parts by weight of the main component liquid of the acrylic resin-based adhesive, 3.5 parts by weight of ibuprofen piconol as an anti-inflammatory agent, and 0.2% by weight of isopropylmethylphenol as an antibacterial agent Parts, sorbitan monooleate 3.5 parts by weight, isopropyl myristate (IPM) 7 parts by weight, butanediol 3.5 parts by weight and lactic acid 7 parts by weight, dibutylhydroxytoluene (BHT) 0.07 part by weight as an antioxidant
  • IPM isopropyl myristate
  • BHT dibutylhydroxytoluene
  • Example 1 When the film was prepared in Example 1, an OPP film substrate used for the production of a conventional urethane film was used as the peelable substrate for casting. The surface of this substrate was a smooth release paper made of OPP. On the other surface (transfer surface) of the film, the unevenness of the OPP release paper surface was transferred, and the Rz of the other surface of the film was 0.9 ⁇ m. About the others, the sample of the skin masking material of the comparative example 1 was prepared on the same conditions as Example 1. FIG.
  • Example 2 When the film was prepared in Example 1, a substrate having a surface Rz of 3 ⁇ m was used as the peelable substrate for casting.
  • As the urethane resin solution a solution in which 100 parts by weight of Leocoat U-6285M (solid content 30% by weight) (manufactured by Toray Cortex Co., Ltd.) and 100 parts by weight of ethyl acetate was used. No fine particles were added to this urethane resin solution. Rz of the other surface (transfer surface) of the film was 3 ⁇ m. About the others, the sample of the skin masking material of the comparative example 2 was prepared on the same conditions as Example 1. FIG.
  • Example 3 When the film was prepared in Example 1, a substrate having a surface Rz of 10 ⁇ m was used as the peelable substrate for casting. Moreover, it replaced with using the urethane resin solution in Example 1, and prepared the pellet of the polyethylene resin. The same kind of fine particles as in Example 1 were kneaded with 26.1 parts by weight of this polyethylene resin in the same amount. The polyethylene resin kneaded with the fine particles was extruded onto the surface of the peelable substrate for casting and peeled from the substrate to obtain a support X. Rz of the other surface (transfer surface) of the film was 5 ⁇ m. About the others, the sample of the skin masking material of the comparative example 3 was prepared on the same conditions as Example 1. FIG.
  • Table 1 shows the characteristic values of the film layer and the skin masking material for the samples of the skin masking material obtained in Examples and Comparative Examples.
  • Example 1 [Consideration of relationship between manufacturing method and Rz on other side]
  • a polyether polyurethane (EU) resin solution was cast on the surface of a peelable substrate for casting having an Rz of 10 ⁇ m to make a prototype.
  • the unevenness of the substrate surface was transferred to the other surface of the film layer.
  • the Rz of this other surface was 10 ⁇ m.
  • Comparative Example 3 a molten polyethylene (PE) resin was prototyped by extruding it onto the surface of a cast peelable substrate having an Rz of 10 ⁇ m. At this time, Rz on the other surface in Comparative Example 1 was 5 ⁇ m.
  • PE polyethylene
  • Comparative Example 3 the same peelable substrate for casting as in Example 1 was used, but the substrate surface unevenness was not sufficiently transferred to the other surface of the film. For this reason, in the sample according to Comparative Example 3, the unevenness formed on the other surface was rounded, and the other surface was slippery.
  • the reason why the unevenness on the substrate surface was not sufficiently transferred in Comparative Example 3 is that when the molten polyethylene (PE) resin was extruded onto the substrate surface, the resin was not a fluid liquid. It is done.
  • the skin masking material having a larger Rz value on the other side is produced by casting the resin solution on the substrate surface rather than extruding the molten resin onto the substrate surface. Suitable for manufacturing.
  • Table 2 shows optical characteristic values of the skin masking material samples obtained in Examples and Comparative Examples.
  • Comparative Example 1 Rz was 0.9 ⁇ m and the total light transmittance was 91.1%.
  • Comparative Example 3 a polyethylene film having Rz of 5 ⁇ m on the other surface dispersed so that fine particles account for 13.3% by weight is used as a material for the film layer, and the total light transmittance is 90.6%. there were.
  • Comparative Example 1 [Consideration of the relationship between fine particles and total light transmittance]
  • the fine particles are dispersed so as to occupy 13.3% by weight with respect to the weight of the film that is the material of the film layer, the Rz on the other surface is 0.9 ⁇ m, and the total light transmittance is It was 91.1%.
  • the film layer did not contain fine particles, Rz was 3 ⁇ m, and the total light transmittance was 95.9%.
  • the comparative example 2 has a higher total light transmittance despite the larger Rz value because the comparative example 2 does not contain fine particles and therefore the incident light is not absorbed and scattered by the fine particles. This is considered to be caused by this.
  • Table 3 shows the medicinal components for the skin contained in the pressure-sensitive adhesive layer of the skin masking material samples obtained in Examples and Comparative Examples.
  • Table 4 shows the weight ratio of the organic compound having a polar group, which is liquid at room temperature, and the pressure-sensitive adhesive layer contained in the pressure-sensitive adhesive layer.
  • Table 5 shows a part of the composition of the monomer and the crosslinking agent for the casting solution used as the material for the pressure-sensitive adhesive layer.
  • the pressure-sensitive adhesive strength of the pressure-sensitive adhesive layer was in the range of 0.1 to 10 (N / 25 mm) and was sticky. In order to improve the cohesive force and the like, it is necessary to add a large amount of the crosslinking agent so that the weight ratio of the solid content of the crosslinking agent to the pressure-sensitive adhesive layer is 2.0% by weight or more.
  • the pressure-sensitive adhesive layer was prepared with a composition in which the weight ratio of the solid content of the isocyanate-based crosslinking agent to the pressure-sensitive adhesive layer was 2.0% by weight or more. Nevertheless, in the samples of Examples 1 to 4, 6, 7, 10 and Comparative Examples 1 to 3, the cohesive force of the pressure-sensitive adhesive layer was weak, and a tendency to cause adhesive residue when the sample was peeled was observed.
  • the cohesion of acrylic acid (AA) as a comonomer and the cohesion caused the cohesive strength of the pressure-sensitive adhesive layer to be weakened was due to the monooleic acid sorbitan ester contained in the casting solution at a high concentration and the crosslinking agent and acrylic acid. It is considered that the cross-linking reaction with (AA) is inhibited and the cross-linking of the adhesive polymer compound is insufficient.
  • HEAA hydroxyethyl acrylamide
  • HSA hydroxyethyl acrylate
  • the solid content of the isocyanate-based crosslinking agent occupies when hydroxyethyl acrylamide (HEAA) is added and copolymerized or when hydroxyethyl acrylate (HEA) is added and copolymerized.
  • Examples 5 and 9 were prepared with a composition having a weight ratio of 0.8% by weight.
  • the cross-linking reaction is sorbitan monooleate compared to the case of copolymerization by adding acrylic acid (AA). Since it was difficult to be inhibited by the ester, it is considered that the crosslinking reaction of the adhesive polymer compound was sufficiently advanced even when the amount of the isocyanate-based crosslinking agent added was small.
  • Example 8 was prepared with a composition of 1 wt%. When an isocyanate-based crosslinking agent protected with a blocking agent was added, it was necessary to add more crosslinking agent than when it was not protected with a blocking agent, but it cannot be said that the crosslinking reaction was inhibited. It is done.
  • Table 6 shows the evaluation results of the cosmetic paste for the samples of Examples and Comparative Examples.
  • the polyethylene (PE) resin of the film layer has low affinity with the powder contained in the cosmetic, and the recesses formed on the other surface are rounded and the powder is likely to slip off. This is also considered to be the reason why the subject felt that the makeup paste was clearly bad in Comparative Example 3. If the resin of the film layer has a high affinity with the powder contained in the cosmetic, such as a polyether polyurethane (EU) resin or a polyester polyurethane resin, it is considered that the effect of applying the makeup is further exhibited.
  • EU polyether polyurethane
  • the resin of the film layer is a polyether polyurethane (EU) resin, and the film used as the material of the film layer has a tensile modulus of 0.2 to 5 MPa. It was within the range, and after applying the sample, the subject did not feel discomfort in the cheek feel.
  • the resin of the film layer is polyethylene (PE) resin, and the film used as the material of the film layer has a tensile modulus of elasticity exceeding 5 MPa. I felt uncomfortable. For this reason, in Comparative Example 3, the test subject unintentionally touched the sample with his / her finger after applying the cosmetic, and the trace of makeup peeling off was conspicuous. From this fact, it is considered that the film serving as the material of the film layer preferably has a tensile elastic modulus in the range of 0.2 to 5 MPa in order to hold the powder on the other surface.
  • Table 7 shows the evaluation results of the mask properties of the samples of the examples and comparative examples.
  • the resin of Comparative Example 1 is polyether polyurethane (EU) and the resin of Comparative Example 3 is polyethylene (PE).
  • EU polyether polyurethane
  • PE polyethylene
  • the total light transmittance of the film layer is 91.1%, while in Comparative Example 3, the total light transmittance of the film layer is 90.6%.
  • the values are approximate, and the evaluation of the mask property is almost the same. Even if the resin of the film layer is different, the skin masking material is considered to exhibit substantially the same masking property if the total light transmittance is approximate.
  • the masking property of the skin masking material is directly determined by the total light transmittance of the film layer. Further, it is considered that the total light transmittance of the film layer is determined by the fine particles dispersed in the film layer and the Rz on the other surface for the reason described above. Therefore, it is considered that the dispersion of fine particles in the film layer and the Rz on the other surface of 6 ⁇ m or more are effective in reducing the total light transmittance of the skin masking material and exhibiting masking properties.
  • Antimicrobial evaluation method About the sample of an Example and a comparative example, antibacterial property was evaluated with the following method.
  • (1) As the agar medium Mueller Hinton Agar Medium-N manufactured by Nissui Pharmaceutical Co., Ltd. was used. The agar medium was sterilized by heating in an autoclave at 121 ° C. for 15 minutes.
  • the sample from which the adhesive protective part had been peeled was placed on the center of the agar medium containing the indicator strain after solidification, with the skin contact surface on the bottom. (4) The medium was allowed to stand for 48 hours in an atmosphere at 37 ° C. to culture the indicator strain. (5) After 48 hours, the diameter of the inhibition circle appearing on the surface of the medium was measured. At that time, the antibacterial properties of the samples were evaluated according to the following criteria. Those that do not allow a stop circle ... ⁇ Blocking circle is recognized and the diameter is less than 15mm ... ⁇ Blocking circle is recognized and the diameter is 15mm or more ... ⁇
  • Table 8 shows the antibacterial evaluation results for the samples of Examples and Comparative Examples.
  • Examples 1 to 10 and Comparative Examples 1 to 3 there was a difference in the antibacterial evaluation results based on the medicinal ingredients for the skin contained in the adhesive layer.
  • the medicinal component was isopropylmethylphenol as an antibacterial agent, and good antibacterial properties were observed in which a blocking circle having a diameter of 15 mm or more was observed.
  • the medicinal component was salicylic acid or lactic acid of ⁇ -hydroxy acids, and a blocking circle with a diameter of less than 15 mm was observed, indicating antibacterial properties.
  • no antibacterial property was shown because the adhesive layer contained no medicinal ingredients for the skin and no inhibition circle was observed.
  • the skin masking material according to the present invention can be used not only as a pharmaceutical product but also in the field of quasi drugs and cosmetics.
  • Table 9 shows the evaluation results of pain sensation by the subjects for the samples of Examples 8 to 10.
  • the anti-inflammatory drug contained in the adhesive layer is ibuprofen piconol.
  • the monomers that were the main components of the adhesive polymer in the adhesive layer were different, and there was a difference in the evaluation of pain sensation by the subjects.
  • the main component is an adhesive polymer obtained by copolymerization of 2-ethylhexyl acrylate (2-EHA), vinyl acetate (VA), and hydroxyethyl acrylate (HEA). It is common to be.
  • the subject was able to feel the pain sensation to such an extent that the subject was picked up by the tip of the needle and felt a little touched.
  • the main component is an adhesive polymer compound copolymerized with 2-ethylhexyl acrylate (2-EHA), methoxyethyl acrylate (MEA), and acrylic acid (AA). The pain sensation was suppressed to such an extent that when I was struck, I felt a bit of a sensation of pain.
  • Example 10 since the adhesive polymer compound has a carboxyl group derived from acrylic acid (AA) and ibuprofen piconol has a pyridine ring, ibuprofen piconol is contained in the adhesive layer by the interaction of these polar groups. It is considered that the release rate was decreased.
  • AA acrylic acid
  • ibuprofen piconol is contained in the adhesive layer by the interaction of these polar groups. It is considered that the release rate was decreased.
  • the skin masking material according to the present invention exhibits sustained release for an organic compound having a polar group such as ibuprofenpiconol when a pressure-sensitive adhesive polymer compound having a polar group is used as a material for the pressure-sensitive adhesive layer.
  • the portion of the back where the sample was not applied was stimulated with a needle tip.
  • the reaction exhibited by the rat when it was pricked with the needle tip was evaluated according to the following criteria. If the rat did not respond to anything ... If the rat shows a reaction to move any body immediately after being pecked ... ⁇ When the rat shows escape behavior to the needle tip ... ⁇
  • Table 10 shows the evaluation results of pain sensation by animal experiments for the samples of Examples 8 to 10.
  • the wound creation date was set to 0, and samples were exchanged every other day thereafter. When changing, the condition of the wound was observed. (5) Based on the wound observation results, wound healing was evaluated when 5 or more of 6 animals in each group met the following criteria. Almost no leakage of exudate was observed, and wound closure was confirmed within 8 days ... ⁇ There was almost no leakage of exudate, and wound closure was observed within 10 days. Leakage of exudate was observed and wound closure was confirmed within 10 days ... ⁇ Leakage of exudate was observed, and wound closure was not observed within 10 days ... ⁇
  • Table 11 shows the evaluation results of wound healing for the samples of Examples 8 to 10.
  • the resin of the film layer was polyethylene (PE), whereas in Examples 1 and 5, it was polyether polyurethane (EU). Since the resin of the film layer was different, the moisture permeability was different, and the results of evaluation of wound healing differed in Examples 1 and 4 compared to Comparative Example 3. In Examples 1 and 5, the moisture permeability is in the range of 900 to 5,000 g / (m 2 ⁇ day), and almost no leakage of leachate is observed, so the smell when the sample is peeled off is weak, 8 days. The wound was closed.
  • PE polyethylene
  • EU polyether polyurethane
  • the wound healing is good when the moisture permeability is high.
  • a film with high moisture permeability is used as the material for the film layer
  • the wound on the wound surface with the skin masking material is suppressed from being steamed, and the growth of normal skin bacteria on the skin around the wound surface is suppressed, and the formation of a clean epidermis is promoted quickly. It is thought that wound healing was improved.
  • a film with low moisture permeability the skin around the wound surface with the skin masking material applied will be steamed, and bacteria will move from the surrounding skin to the wound surface, causing bacteria to grow and adversely affect wound healing. It is thought.
  • the strong odor when a sample using a film with low moisture permeability is peeled off is considered to be caused by the increase of moisture in the skin around the wound surface, resulting in a moist state and the growth of normal bacteria on the skin.
  • Example 1 and Comparative Example 3 healing was achieved without making a crust, and a clean epidermis was formed. Since this wound healing effect was also observed in Example 1 and Comparative Example 3 in which the adhesive layer does not contain a medicinal component for the skin, it does not result from the medicinal component. This effect is due to the wound surface being covered with the film layer and the pressure-sensitive adhesive layer constituting the sample and maintained in a wet state in each of Examples 1, 5 and Comparative Example 3.
  • the skin masking material according to the present invention can be attached to the skin of the part in order to hide the extraneous part generated on the skin, and further, a cosmetic such as a foundation or a concealer can be placed on the part to make it inconspicuous. Furthermore, when the skin masking material according to the present invention contains a medicinal component for the skin in the adhesive layer, the skin masking material is applied to a different part to make it inconspicuous, and at the same time, treat the foreign part. Can do. In addition, the skin masking material according to the present invention can correct wrinkles and sagging of the skin by raising the loose skin when applied to the skin with loose face depending on the shape and the way of applying the skin masking material.
  • the skin masking material affixed at this time is made inconspicuous by applying makeup, the face can appear younger.
  • the skin masking material according to the present invention can be affixed to the surface of an object other than the skin, eliminates the gloss of the surface, suppresses reflection of light on the surface, and prevents the surface from slipping. You can do it. Even when such a surface includes a curved surface or a spherical surface, the skin masking material according to the present invention can be applied.

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CN109475434A (zh) * 2016-08-09 2019-03-15 日东电工株式会社 皮肤贴附材料以及皮肤贴附材料卷绕体
JP2019088765A (ja) * 2017-11-10 2019-06-13 凸版印刷株式会社 貼付剤用支持体フィルム、積層体及び貼付剤
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