WO2012176886A1 - 磁気共鳴イメージング装置および撮像位置設定支援方法 - Google Patents
磁気共鳴イメージング装置および撮像位置設定支援方法 Download PDFInfo
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
- A61B5/4538—Evaluating a particular part of the muscoloskeletal system or a particular medical condition
- A61B5/4566—Evaluating the spine
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/543—Control of the operation of the MR system, e.g. setting of acquisition parameters prior to or during MR data acquisition, dynamic shimming, use of one or more scout images for scan plane prescription
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
- G01R33/4833—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices
Definitions
- the present invention relates to an imaging position setting support technique in a magnetic resonance imaging (hereinafter referred to as “MRI”) apparatus.
- MRI magnetic resonance imaging
- a magnetic resonance imaging (hereinafter referred to as “MRI”) device measures a nuclear magnetic resonance (hereinafter referred to as “NMR” or echo) signal generated by a nuclear spin that constitutes a subject, particularly a human tissue, and the head thereof. It is a device that images two-dimensionally or three-dimensionally the forms and functions of the abdomen, limbs, and the like.
- the NMR signal is given a phase encoding that varies depending on the gradient magnetic field, is frequency-encoded, and is measured as time-series data.
- This NMR signal is reconstructed into an image by two-dimensional or three-dimensional Fourier transform.
- An area to be imaged is called an imaging slice, and an operator sets the position (imaging position) via a GUI or the like.
- an imaging region including not only an imaging region at the time of single slice imaging but also a three-dimensional region at the time of multi-slice imaging is referred to as an imaging slice.
- an anatomically determined cross section is usually imaged for each examination site.
- This cross section is called an inspection cross section.
- the inspection cross section includes, for example, the OM line for the head and the meniscus position for the knee.
- the operator sets the imaging position of the examination section as an imaging slice for each subject.
- the setting accuracy and required time of the imaging position depend on the skill level of the operator. For example, in an anatomically complex region such as a joint region, considerable skill is required to set the imaging position so that the region to be examined (for example, ligament or cartilage) is accurately included in the imaging slice. .
- Non-Patent Document 1 a function (automatic positioning function) for automatically setting the imaging position of each examination section of a designated examination site has been proposed (for example, see Non-Patent Document 1).
- the automatic positioning function disclosed in Non-Patent Document 1 uses a slice plan setting information obtained by learning an imaging position setting pattern executed by an operator on a 3D image obtained by 3D (3D) volume imaging. The imaging position is calculated. The imaging position can be easily set without depending on the skill level of the operator.
- a function of automatically determining an imaging position using a 2D scanogram has also been proposed (see, for example, Non-Patent Document 2).
- the imaging position of the examination section varies depending on the case and the intended examination.
- the examination site is a spine or the like
- there are a plurality of vertebral bodies and intervertebral discs to be imaged there are a plurality of examination sections.
- the adjustment work is performed on the positioning image, but it may impair the time reduction that is an advantage of the automatic positioning function.
- the present invention has been made in view of the above circumstances, and magnetic resonance imaging capable of maximizing the effect of the automatic positioning function without increasing the burden on the operator even when imaging an examination site having a plurality of examination sections.
- An object of the present invention is to provide an imaging position setting support technique in an apparatus.
- a magnetic resonance imaging apparatus and an imaging position setting support technology capable of maximizing the effect of the automatic positioning function without increasing the burden on the operator even when imaging an examination site having a plurality of examination sections. Can be provided.
- the block diagram which shows the whole structure of the MRI apparatus of 1st embodiment Functional block diagram of the control processing system of the first embodiment Explanatory drawing for demonstrating the example of an output pattern setting screen of 1st embodiment Explanatory drawing for demonstrating the example of a detection result display screen of 1st embodiment
- (a)-(c) is explanatory drawing for demonstrating the specific example of the stack display of 1st embodiment.
- (a)-(c) is explanatory drawing for demonstrating the specific example of the stack display of 1st embodiment.
- (a)-(g) is explanatory drawing for demonstrating the adjustment method of the output imaging position by the adjustment part of 1st embodiment.
- (a)-(c) is explanatory drawing for demonstrating the specific example of the stack display of 1st embodiment.
- (a)-(c) is explanatory drawing for demonstrating the specific example of the stack display of 1st embodiment.
- Functional block diagram of the control processing system of the second embodiment Explanatory drawing for demonstrating the example of a detection result display screen of 2nd embodiment
- (a)-(c) is explanatory drawing for demonstrating the stack display process of 2nd embodiment.
- Flow chart of stack display processing of the second embodiment (a)-(c) is explanatory drawing for demonstrating the stack display process of 2nd embodiment.
- (a)-(c) is explanatory drawing for demonstrating the other example of the stack display process of 2nd embodiment.
- (a)-(c) is explanatory drawing for demonstrating the other example of the area
- (a)-(d) is explanatory drawing for demonstrating the modification of the stack display process of 2nd embodiment.
- (a)-(d) is explanatory drawing for demonstrating the modification of the stack display process of 2nd embodiment.
- (a)-(d) is explanatory drawing for demonstrating the modification of the stack display process of 2nd embodiment.
- (a)-(c) is explanatory drawing for demonstrating the area
- (a)-(c) is explanatory drawing for demonstrating the adjustment process at the time of the multi imaging of 2nd embodiment.
- the magnetic resonance imaging apparatus of the present invention is a magnetic resonance imaging apparatus including a control processing system and a display device for controlling and calculating the operation of the entire apparatus, and the control processing system is configured to perform an examination.
- An imaging condition setting unit that accepts, an imaging position setting unit that sets an imaging position, and an imaging unit that captures an imaging position set by the imaging position setting unit, wherein the imaging position setting unit is a scanogram acquired in advance
- the automatic positioning unit that detects the positions of all examination sections of the examination site accepted by the imaging condition setting unit, and the scan device displays the scanogram image on the display device, and the position of the position detected by the automatic positioning unit
- a detection result display unit that sets one or more predetermined positions in the imaging position and displays a stack at the imaging position on the scanogram image; It is characterized by providing.
- the imaging position setting unit further includes an output pattern setting unit that sets the inspection cross section set as the imaging position as an output pattern, and the one or more predetermined positions are positions detected by the automatic positioning unit Of the inspection section set as the output pattern.
- the output pattern setting unit generates an output pattern setting screen corresponding to the received examination site, displays the output pattern setting screen on the display device, and accepts the setting of the inspection section to be output via the output pattern setting screen. It is characterized by.
- it further includes a data holding unit that holds in advance an examination section that can be selected for each examination site as an output pattern, and the output pattern setting unit receives the selection from the output pattern held in the data holding unit, The setting of the inspection section to be output is received.
- Each inspection section is composed of one or more slices, and the detection result display unit displays, as the stack, an outer frame in a range specified by all slices of each of the output inspection sections. .
- the detection result display unit displays the stack in a blinking manner.
- the detection result display unit switches between displaying and not displaying the stack according to an instruction from an operator or at a predetermined time interval.
- the detection result display unit displays the stack in a display mode that is different for each inspection section.
- the detection result display unit includes a selection receiving unit that receives selection of a position set as the imaging position. And an input device that receives an input from an operator, wherein the detection result display unit performs a simple display at a position detected by the automatic positioning unit on the scanogram image, and the selection reception unit includes the input
- the selection of the simple display is accepted, the simple display does not impair the visibility of the scanogram image, and the position and inclination of the detected inspection cross section are detected. It is characterized by a display that can be grasped.
- the imaging position setting unit further includes an output pattern setting unit that sets the inspection cross section set as the imaging position as an output pattern
- the detection result display unit includes the automatic positioning unit on the scanogram image.
- a simple display is performed at the position of the inspection section set as the output pattern in the detected position, and the selection receiving unit receives the selection of the simple display via the input device, thereby The selection is accepted, and the simple display is a display that does not impair the visibility of the scanogram image and can grasp the position and inclination of the detected inspection section.
- the image processing apparatus further includes an input device that receives an input from an operator, and the selection receiving unit receives a selection of an area on the scanogram image via the input device, and includes a position detected by the automatic positioning unit. The position in the selected area is set as the selected position.
- the imaging position setting unit further includes an output pattern setting unit that sets, as an output pattern, the inspection section set as the imaging position, and the selection receiving unit is connected to the scanogram image via the input device. Accepting the selection of the area, the position of the inspection section set as the output pattern in the position detected by the automatic positioning unit, and the position in the selected area as the selected position It is characterized by.
- the imaging position setting unit further includes an adjustment unit that adjusts the imaging position set by the detection result display unit, and the imaging unit performs imaging of the adjusted imaging position.
- the adjustment unit displays an adjustment instruction button used to adjust the imaging position on the display device together with the stack displayed by the detection result display unit, and accepts the adjustment of the imaging position via the adjustment instruction button. It is characterized by that.
- the apparatus further includes an input device that receives an instruction from an operator, and the adjustment unit updates at least one of the display position and the number of the stack according to an instruction from the operator with respect to the stack via the input device.
- the adjustment is performed.
- each inspection section is composed of one or more slices, and the adjustment unit accepts a change in the number of slices of the inspection section in accordance with an instruction from an operator for the stack.
- the adjustment instruction button includes a button for instructing a moving direction of the stack selected by an operator and a button for instructing the arrangement of the stack selected by the operator.
- the imaging position setting support method of the present invention provides imaging that supports setting of the imaging position of an examination site having a plurality of examination sections in a magnetic resonance imaging apparatus including a control processing system that controls and calculates the operation of the entire apparatus.
- An automatic positioning step in which the control processing system detects the positions of all examination sections of the examination site on a scanogram image acquired in advance, and the control processing system
- a detection result display step of setting one or more predetermined positions as the imaging position, and displaying a stack while ensuring visibility at the imaging position of the scanogram image.
- FIG. 1 is a block diagram showing the overall configuration of the MRI apparatus 100 of the present embodiment.
- the MRI apparatus 100 of the present embodiment obtains a tomographic image of a subject using an NMR phenomenon, and as shown in FIG. 1, a static magnetic field generation system 120, a gradient magnetic field generation system 130, a transmission system 150, A receiving system 160, a control processing system 170, and a sequencer 140.
- the static magnetic field generation system 120 generates a uniform static magnetic field in the direction perpendicular to the body axis in the space around the subject 101 if the vertical magnetic field method is used, and in the body axis direction if the horizontal magnetic field method is used.
- the apparatus includes a permanent magnet type, normal conducting type or superconducting type static magnetic field generating source disposed around the subject 101.
- the gradient magnetic field generation system 130 is a gradient magnetic field coil 131 wound in the three-axis directions of X, Y, and Z, which is the coordinate system (static coordinate system) of the MRI apparatus 100, and a gradient magnetic field power source that drives each gradient magnetic field coil 132, and by driving the gradient magnetic field power supply 132 of each gradient coil 131 in accordance with a command from the sequencer 140 described later, gradient magnetic fields Gx, Gy, Gz are generated in the three axis directions of X, Y, and Z. Apply.
- the transmission system 150 irradiates the subject 101 with a high-frequency magnetic field pulse (hereinafter referred to as “RF pulse”) in order to cause nuclear magnetic resonance to occur in the nuclear spins of the atoms constituting the biological tissue of the subject 101.
- RF pulse high-frequency magnetic field pulse
- the high frequency oscillator 152 generates an RF pulse and outputs it at a timing according to a command from the sequencer 140.
- the modulator 153 amplitude-modulates the output RF pulse, and the high-frequency amplifier 154 amplifies the amplitude-modulated RF pulse and supplies the amplified RF pulse to the transmission coil 151 disposed close to the subject 101.
- the transmission coil 151 irradiates the subject 101 with the supplied RF pulse.
- the receiving system 160 detects a nuclear magnetic resonance signal (echo signal, NMR signal) emitted by nuclear magnetic resonance of the nuclear spin constituting the living tissue of the subject 101, and receives a high-frequency coil (receiving coil) on the receiving side. 161, a signal amplifier 162, a quadrature detector 163, and an A / D converter 164.
- the reception coil 161 is disposed in the vicinity of the subject 101 and detects an NMR signal in response to the subject 101 induced by the electromagnetic wave irradiated from the transmission coil 151.
- the detected NMR signal is amplified by the signal amplifier 162 and then divided into two orthogonal signals by the quadrature phase detector 163 at the timing according to the command from the sequencer 140, and each is digitally converted by the A / D converter 164. It is converted into a quantity and sent to the control processing system 170.
- Sequencer 140 repeatedly applies RF pulses and gradient magnetic field pulses according to a predetermined pulse sequence.
- the pulse sequence describes the high-frequency magnetic field, the gradient magnetic field, the timing and intensity of signal reception, and is stored in the control processing system 170 in advance.
- the sequencer 140 operates in accordance with an instruction from the control processing system 170 and transmits various commands necessary for collecting tomographic image data of the subject 101 to the transmission system 150, the gradient magnetic field generation system 130, and the reception system 160.
- the control processing system 170 controls the entire MRI apparatus 100, performs various data processing operations, displays and stores processing results, and includes a CPU 171, a storage device 172, a display device 173, and an input device 174.
- the storage device 172 includes a hard disk and an external storage device such as an optical disk or a magnetic disk.
- the display device 173 is a display device such as a CRT or a liquid crystal.
- the input device 174 is an interface for inputting various control information of the MRI apparatus 100 and control information of processing performed by the control processing system 170, and includes, for example, a trackball or a mouse and a keyboard.
- the input device 174 is disposed in the vicinity of the display device 173. The operator interactively inputs instructions and data necessary for various processes of the MRI apparatus 100 through the input device 174 while looking at the display device 173.
- the CPU 171 implements each process of the control processing system 170 such as control of the operation of the MRI apparatus 100 and various data processing by executing a program stored in the storage device 172 in accordance with an instruction input by the operator. For example, when data from the reception system 160 is input to the control processing system 170, the CPU 171 executes processing such as signal processing and image reconstruction, and a tomographic image of the subject 101 as a result is displayed on the display device 173. The information is displayed and stored in the storage device 172.
- the transmission coil 151 and the gradient magnetic field coil 131 are opposed to the subject 101 in the vertical magnetic field method, and in the horizontal magnetic field method. It is installed so as to surround the subject 101. Further, the receiving coil 161 is installed so as to face or surround the subject 101.
- the nuclide to be imaged by the MRI apparatus which is widely used clinically, is a hydrogen nucleus (proton) which is a main constituent material of the subject 101.
- the MRI apparatus 100 by imaging information on the spatial distribution of proton density and the spatial distribution of relaxation time in the excited state, the form or function of the human head, abdomen, limbs, etc. can be expressed two-dimensionally or three-dimensionally. Take an image.
- the imaging procedure using the MRI apparatus 100 is as follows. First, an instruction is sent to the transmission system 150 according to the pulse sequence, and the subject 101 is irradiated with an RF pulse from the transmission coil 151.
- the echo signal generated from the subject 101 by the irradiation of the RF pulse is given different phase encoding depending on the gradient magnetic field. As the number of phase encodings, values such as 128, 256, and 512 are usually selected per image.
- Each echo signal is detected by the receiving coil 161.
- the echo signal is usually detected as a time-series signal composed of 128, 256, 512, and 1024 sampling data. These data are transmitted from the receiving system 160 to the control processing system 170. Then, in the control processing system 170, image processing such as two-dimensional Fourier transform is performed, and one reconstructed image is generated.
- the above imaging is performed for each imaging position set as an imaging slice.
- the imaging position is specified using, for example, a coordinate system (referred to as device coordinates) set in advance in the MRI apparatus 100.
- the MRI apparatus 100 realizes imaging of the cross section of the specified imaging position by adjusting the slice selection gradient magnetic field and the irradiation frequency of the RF pulse.
- an imaging position of a desired inspection cross section is determined using an automatic positioning function, and imaging is performed. At this time, adjustment work caused by a plurality of inspection sections is facilitated.
- the control processing system 170 of the present embodiment includes an imaging condition setting unit 210 that accepts various settings for executing an inspection such as imaging parameters (scan parameters), and an imaging position.
- Imaging position setting unit 220 for setting the imaging position
- imaging unit 230 for performing the actual imaging at the imaging position set by the imaging position setting unit 220, data used for these processes, various data obtained during the process, and processing results
- a data holding unit 240 that holds the data.
- the imaging parameters received by the imaging condition setting unit 210 include the examination site and the number of stacks.
- the imaging position setting unit 220 generates an automatic positioning unit 221 that automatically detects the imaging positions of all examination sections of the designated examination site, and an output pattern setting screen corresponding to the designated examination site, and sets the output pattern
- An instruction of a desired inspection section is received as an automatic positioning output from the operator via the screen, and an output pattern setting unit 222 that is set as an output pattern, and an output pattern setting unit 222 in the imaging position detected by the automatic positioning unit 221
- a detection result display unit 223 that displays a stack while ensuring visibility at the output imaging position, and an adjustment unit 224 that supports adjustment of the output imaging position.
- the data holding unit 240 is constructed in the storage device 172, and other functions of the control processing system 170 are realized by the CPU 171 loading a program held in the storage device 172 into the memory and executing it.
- the automatic positioning unit 221 uses a known method disclosed in Non-Patent Document 1 or Non-Patent Document 2 or the like, and determines the position (imaging position) of the imaging slice corresponding to each examination section of the examination site designated by the operator. Calculate automatically.
- the automatic positioning unit 221 performs scanogram imaging, and detects the imaging position of the examination site on the obtained scanogram image.
- the position information of the detected imaging position is held in the data holding unit 240 as described above for each imaging position.
- the stack is displayed only at the imaging position used for the main imaging from the imaging positions detected by the automatic positioning unit 221.
- the imaging position for displaying the stack is set as an output pattern by the output pattern setting unit 222.
- the designation is accepted by specifying the inspection cross section.
- the automatic positioning unit 221 detects the imaging positions of all examination sections included in the examination site.
- the automatic positioning unit 221 may be configured to detect only the cross section designated as the inspection cross section.
- the output pattern setting unit 222 generates an output pattern setting screen corresponding to the examination site, displays it on the display device 173, and receives an instruction from the operator.
- FIG. 3 shows an example of an output pattern setting screen 300 displayed when the examination site is a spinal region.
- the output pattern setting screen 300 includes an output pattern setting area 310, an output pattern name setting area 320, and a save button 330.
- the output pattern setting area 310 accepts the selection of the inspection section from the imaging positions detected by the automatic positioning unit 221. For this reason, the output pattern setting area 310 includes an inspection cross section setting area 311 that accepts the setting of the inspection cross section. Some inspection sections have a plurality of imaging positions. In this case, the setting of the detected number is also accepted. Therefore, a detection number setting area 312 for accepting setting of the detection number is further provided.
- the operator selects an inspection section through the inspection section setting area 311.
- information for specifying the examination section of the examination site is displayed so as to be selectable in a display mode such as a radio button or a pull-down menu.
- the examination section information displayed in the examination section setting area 311 and the image displayed in the detected number setting area 312 are held in advance in the data holding unit 240 in association with the examination site.
- the image displayed in the detection number setting area 312 is a standard image of the part.
- the examination target is a vertebral body or an intervertebral disc.
- the automatic positioning unit 221 automatically creates a plane parallel to the vertebral body including the vertebral body (vertebral body surface) and a plane parallel to the intervertebral disk including the intervertebral disc (discs). Detect both imaging positions of the surface. The operator selects one of the vertebral body surface, the intervertebral disc surface, and both the vertebral body surface and the intervertebral disc surface as the examination section.
- the operator selects the imaging range by setting the number of inspection sections detected in the detection number setting area.
- the output pattern name setting area 320 is an area in which information for specifying the output pattern set in the output pattern setting area 310 is input and set. By pressing the save button 330, the output pattern set in the output pattern setting area 310 is registered in the data holding unit 240 in association with the output pattern name set in the output pattern name setting area 320.
- the detection result display unit 223 displays the result on a positioning image displayed on a detection result display screen described later.
- An example of the detection result display screen 400 is shown in FIG.
- the detection result display screen 400 is generated by the imaging position setting unit 220 using the data held in the data holding unit 240 and displayed on the display device 173.
- the detection result display screen 400 includes a display area 401 for displaying the positioning image 410, an adjustment instruction area 430 for displaying various buttons used for adjusting the output imaging position, and the determination of the output imaging position.
- An imaging start button 440 that accepts an intention and an instruction to start imaging is provided.
- the detection result display unit 223 displays the stack 420 at the output imaging position on the positioning image 410.
- the stack 420 is displayed in a display form that can ensure the visibility of the positioning image 410. That is, the stack 420 is displayed in such a display manner that the structure of the examination site and the state of the tissue of the positioning image 410 can be grasped.
- the detection result display screen 400 may be configured to be generated by the detection result display unit 223 and displayed on the display device 173 in response to the result of the positioning process.
- FIGS. 5A to 5C show specific examples of the stack 420 displayed on the positioning image 410 by the detection result display unit 223.
- FIG. Also here, the case where the examination site is the spinal region is illustrated.
- FIG. 5 (a) is an example in which, for each examination section, an output imaging position composed of a plurality of slices constituting the examination section is used as an imaging range, and only the rectangular outer frame 421 is displayed as a stack 420.
- the rectangular area indicating the imaging range is calculated from the output imaging position, the number of slices and the slice interval set by the imaging parameters.
- FIG. 5 (b) shows an example in which the stack 420 is displayed blinking at the output imaging position. All of a plurality of slices constituting the inspection section are displayed blinking.
- FIG. 5 (c) is an example of controlling display / non-display of the stack 420 in accordance with an instruction from the operator.
- the operator controls the display / non-display by instructing the stack 420 of the output imaging position where the display / non-display is desired to be changed by the input device 174 such as a mouse.
- the display / non-display of the stack 420 at all output imaging positions may be controlled at a time according to an instruction from the operator. Further, the stack 420 may be displayed / hidden automatically and alternately according to an operator's instruction or at a predetermined time interval.
- a plurality of display modes as shown in FIGS. 5A to 5C may be prepared so that the operator can select the display mode of the stack 420.
- the output pattern setting screen 300 includes an area for selecting a display mode, and the operator selects a display mode via the output pattern setting screen 300.
- the detection result display unit 223 displays the stack 420 according to the operator's selection. When there are a plurality of inspection sections set as output patterns, the detection result display unit 223 may change the display mode for each inspection section.
- the number of imaging positions (specified number of stacks) specified as imaging parameters may differ from the number of output imaging positions.
- the display of the stack 420 by the detection result display unit 223 in such a case will be described.
- FIGS. 6 (a) to 6 (c) are diagrams for explaining a display method of the stack 420 for each relationship between the designated number of stacks and the number of output imaging positions.
- Fig. 6 (a) shows the case where the number of designated stacks matches the number of output imaging positions.
- the stack 420 is displayed at each output imaging position. That is, as many stacks 420 as the specified number of stacks are displayed.
- Fig. 6 (b) shows the case where the number of designated stacks is smaller than the number of output imaging positions (the number of designated stacks ⁇ the number of output imaging positions).
- the stack 420 is placed at each output imaging position for a specified number of stacks in a centric order from the output imaging position at the center in the vertical direction (body axis direction) alternately toward the output imaging position at the end. indicate.
- a display mode different from that of the stack 420 is displayed at the remaining output imaging positions.
- This display is called a surplus stack 422.
- the surplus stack 422 is displayed with, for example, a broken line, a color different from the stack 420, and the like.
- Fig. 6 (c) shows the case where the number of designated stacks is greater than the output imaging position (specified stack number> number of output imaging positions).
- the stack 420 is displayed at each output imaging position by the number of output imaging positions in a centric manner from the output imaging position in the center in the vertical direction (body axis direction). Then, a display mode different from that of the stack 420 is displayed in parallel with the stack 420 at the end for the number of remaining designated stacks. This display is called a lack stack 423.
- the shortage stack 423 is displayed with, for example, a broken line, a color different from the stack 420, and the like. Further, the insufficient stack 423 is displayed centricly after the stack 420 at a position where an average interval between the respective imaging position intervals is provided.
- the adjustment unit 224 assists the operator in adjusting the output imaging position. Support is performed on the detection result display screen 400.
- the adjustment unit 224 receives instructions from the operator via the detection result display screen 400 and the input device 174, such as selection, movement, and deletion of the stack 420, and resetting of the output imaging position, and provides support. Selection of the stack 420 is performed by, for example, an operation such as clicking with the mouse pointer placed on the stack 420 to be selected, or designating an area having a predetermined shape including the stack 420 to be selected. Further, each time an operation such as movement, deletion, or resetting is performed, the position information of each imaging position registered in the data holding unit 240 is updated. An example of support when the number of designated stacks and the number of output imaging positions are different will be described.
- an insufficient stack 423 is displayed as shown in FIG. 6 (c). If there is clearly an unnecessary one, the operator selects an unnecessary shortage stack 423 and instructs to delete it.
- the adjustment unit 224 deletes the insufficient stack 423 that has received a deletion instruction from the operator. At this time, the adjustment unit 224 also reduces the number of designated stacks set by the imaging parameters by the number of deleted designated stacks. Further, when there is a position where an image should actually be captured due to omission of detection, the operator moves the insufficient stack 423 to the position. When such an operation is received from the operator, the adjustment unit 224 sets the designated position as a new output imaging position, and displays the stack 420 at the position.
- the surplus stack 422 is displayed as shown in FIG. 6 (b).
- the operator wants to change the imaging position without changing the designated number of stacks, the operator selects the stack 420 displayed at a position where imaging is not required and moves it to a desired imaging position.
- the adjustment unit 224 displays the stack 420 at the output imaging position after movement, and displays the surplus stack 422 at the position before movement.
- FIG. 7A shows how the stack 420 and the surplus stack 422 before adjustment are displayed.
- the adjustment unit 224 is arranged in the adjustment instruction area 430 of the detection result display screen 400, and includes a movement direction instruction button (up / down button) 431, an arrangement instruction button (buttons from top to bottom, buttons from bottom to bottom, every other button) 432 An adjustment instruction using a position adjustment instruction button such as, etc. is received, and adjustment of the output imaging position is supported.
- FIG. 7 (b) shows the processing when the entire stack 420 is moved up and down.
- the operator selects all the stacks 420 and presses the movement direction instruction button (up / down button) 431.
- the adjustment unit 224 sets the output imaging positions at both ends to the upper and lower limits, and raises and lowers all the stacks 420 according to each output imaging position between them.
- FIG. 7 (c) shows a process for moving the selected stack 420 up and down.
- the operator selects an arbitrary stack 420 to be moved and presses a moving direction instruction button (up / down button) 431.
- the adjustment unit 224 sets the output imaging positions at both ends as upper and lower limits, and moves the selected stack 420 up and down in accordance with each output imaging position between them.
- the output imaging position is skipped and moved.
- FIG. 7 (d) shows processing when the selected stack 420 is moved to a desired output imaging position.
- the operator selects an arbitrary stack 420 to be moved and moves it to an output imaging position where the stack 420 is not arranged. Selection and movement are performed, for example, by clicking and dragging the input device 174 such as a mouse.
- the adjustment unit 224 moves the selected stack 420 to the destination output imaging position.
- FIG. 7 (e) and FIG. 7 (f) show processing when the stack 420 is arranged in order from the imaging position at either end for each detected imaging position.
- the operator gives an instruction by pressing the buttons in order from the top of the placement instruction buttons 432 or the buttons in order from the bottom.
- the adjustment unit 224 displays the stack 420 at the output imaging position according to the instructions.
- FIG. 7 (g) shows a process in which every other stack 420 is arranged at a plurality of detected imaging positions.
- the operator gives an instruction by pressing every other button in the placement instruction buttons 432.
- the adjustment unit 224 causes the stack 420 to be displayed at the output imaging position in accordance with the instruction.
- the stack 420 is displayed at each output imaging position every other centric from the output imaging position at the center in the vertical direction.
- the adjustment unit 224 supports the adjustment of the stack arrangement by the operator.
- the operator can easily move each stack 420 to the output imaging position by pressing a prepared button on the detection result display screen 400, using a mouse as a normal operation interface, or the like.
- the operator adjusts the position of the stack 420 after confirming the position on the positioning image, reduces the number of designated stacks, increases the stack 420. Adjustments such as alignment may be performed.
- the adjustment unit 224 also supports such adjustment.
- the adjustment unit 224 displays the stack 420 at the position after movement (output imaging position). It should be noted that a button for receiving an instruction to return the display position of the stack 420 from a position after movement to a position before movement by mouse drag, a special click operation, or the like may be prepared.
- the operator when the number of designated stacks is to be reduced, the operator reduces the number of designated stacks of imaging parameters and designates the desired number of stacks 420 with a mouse click or the like. Upon receiving such an instruction, the adjustment unit 224 erases the display of the stack 420 at the output imaging position designated by the mouse click. Further, a button for receiving an instruction to delete the display of the selected stack 420 may be prepared. Note that the process of reducing the number of designated stacks of imaging parameters may be automated. In other words, the number of stacks designated by the imaging parameter may be reduced by the number of stacks 420 deleted by the operator in conjunction with the number of stacks 420 to be displayed.
- the operator increases the number of designated stacks of imaging parameters and performs line drawing at the position where the stack 420 is to be arranged on the positioning image.
- the adjustment unit 224 displays the stack 420 as the output imaging position where the line drawing is received. Note that the process of increasing the number of designated stacks of imaging parameters may be automated. That is, the number of stacks designated by the imaging parameter may be increased by the number of stacks 420 increased by the operator in conjunction with the number of stacks 420 to be displayed.
- the operator designates a line passing through the center of each stack 420 on the positioning image.
- the designated line is, for example, a line along the spinal column.
- the adjustment unit 224 changes the display position of each stack 420 so that the center is on the line designated by the operator, and performs re-display.
- the operator designates a position that should be the center of the stack 420 on the positioning image on the positioning image by mouse click or the like.
- the adjustment unit 224 moves the stack 420 so that the center comes to the position specified by the operator, and displays it again.
- the imaging position setting unit 220 receives an imaging start instruction by the imaging start button 440 on the detection result display screen 400, the output imaging position at which the stack 420 is displayed at that time is set as the imaging position of the main imaging. To do. Then, using the information of each output imaging position held in the data holding unit 240, imaging parameters are calculated so that imaging is performed at the imaging position.
- the imaging unit 230 uses the imaging parameters set by the operator and the imaging parameters calculated by the imaging position setting unit 220 to issue an instruction to the sequencer 140 according to the pulse sequence to perform imaging.
- FIG. 8 (a) is a processing flow at the time of inspection according to the present embodiment.
- the imaging condition setting unit 210 receives an examination site (step S1001).
- the output pattern setting unit 222 displays on the display device 173 an output pattern setting screen 300 that accepts the setting of the accepted output pattern of the examination site, and accepts the setting of the output pattern from the operator (step S1002).
- the setting of the output pattern name is accepted, and the output pattern is stored in the data holding unit 240 in association with the output pattern name (step S1003).
- the imaging condition setting unit 210 creates and stores an inspection protocol (step S1004).
- the inspection protocol is a group of a plurality of images constituting the inspection according to the inspection procedure.
- a general inspection protocol includes scanogram imaging for acquiring a positioning image and main imaging for acquiring a diagnostic image.
- the automatic positioning unit 221 detects the imaging position using the positioning image acquired by this scanogram imaging. When there is one imaging position, the main imaging is performed at the imaging position determined by the automatic positioning unit 221.
- the imaging condition setting unit 210 displays a protocol setting screen 500 on the display device 173, and accepts settings necessary for creating an inspection protocol via the protocol setting screen 500.
- the protocol setting screen 500 accepts imaging parameter settings for each imaging performed in the scanogram imaging and the main imaging.
- An imaging type setting area 510 for receiving imaging settings to be executed, a parameter setting area 520 for receiving imaging parameter settings for each set imaging, and a save button 530 are provided.
- a setting for whether or not to perform automatic positioning is accepted.
- the name saved in step S1003 is displayed as the output pattern.
- the imaging condition setting unit 210 accepts pressing of the save button 530, and saves the contents of the setting accepted via the protocol setting screen 500 in the data holding unit 240 as an inspection protocol. Upon saving, the setting of the inspection protocol name is accepted.
- the imaging condition setting unit 210 displays the inspection screen 600 shown in FIG. 10 on the display device 173, and loads the protocol stored in step S1004 (step S1005).
- the inspection screen 600 receives an imaging type display area 610 for displaying the imaging type executed in the inspection, a parameter display area 620 for displaying the imaging parameter for each imaging type, and an instruction to start the inspection.
- An inspection start button 630 is displayed. The operator confirms the display contents and presses the examination start button 630.
- the imaging unit 230 starts imaging that constitutes the examination.
- scanogram imaging is started (step S1007).
- the automatic positioning unit 221 performs automatic positioning (step S1008).
- the detection result display unit 223 performs a stack display process for displaying the stack 420 on the detection result display screen 400 (step S1009).
- FIG. 8B shows the flow of the stack display process of the present embodiment.
- the designated stack number S and the output imaging position number L are compared (steps S1101 and S1103).
- the stack 420 is displayed at each output imaging position (step S1102).
- S stacks 420 are displayed.
- the stack 420 having the designated stack number S is displayed at the predetermined output imaging position and the remaining output imaging positions as shown in FIG. (LS) surplus stacks 422 are displayed (step S1104).
- the stack 420 is displayed for each output imaging position by the number L of output imaging positions, and the remaining (SL) pieces, The insufficient stack 423 is displayed at a predetermined position (step S1105).
- the imaging position setting unit 220 waits for an instruction to start the actual imaging from the operator via the detection result display screen 400 (step S1010).
- the imaging position setting unit 220 calculates imaging parameters so that the output imaging position where the stack 420 is displayed at that time is the imaging position of main imaging (step S1011). Then, the imaging unit 230 starts main imaging using the calculated imaging parameter (step S1012).
- the adjustment unit 224 adjusts the display position of the stack 420 according to the received instruction by the above-described method. (Step S1013). Then, the imaging position setting unit 220 proceeds to step S1010 and waits for an instruction to start actual imaging.
- step S1013 the adjustment by the adjustment unit 224 in step S1013 is performed according to an instruction from the operator as described above. Also, when the number of designated stacks is smaller than the number of output imaging positions, adjustment is supported by the method shown in FIGS. 7 (a) to (g).
- the control processing system 170 of the present embodiment performs the inspection according to the above procedure.
- the MRI apparatus 100 of the present embodiment is the MRI apparatus 100 including the control processing system 170 and the display device 173 that perform control and calculation of the operation of the entire apparatus, and the control processing system 170 includes: An imaging condition setting unit 210 that accepts settings for executing an inspection, an imaging position setting unit 220 that sets an imaging position, and an imaging unit 230 that performs imaging at the imaging position set by the imaging position setting unit 220.
- the imaging position setting unit 220 includes an automatic positioning unit 221 that detects the positions of all examination sections of the examination site received by the imaging condition setting unit 220 on a scanogram image acquired in advance, and the display device 173 While displaying the scanogram image, one or more predetermined positions among the positions detected by the automatic positioning unit 221 are set as the imaging position, and visibility is ensured at the imaging position on the scanogram image. And a detection result display unit 223 for displaying the stack 420.
- the imaging position setting unit 221 further includes an output pattern setting unit 222 that sets the inspection section set as the imaging position as an output pattern, and the automatic positioning unit 221 sets the one or more predetermined positions. Of the detected positions, the position of the inspection cross section set as the output pattern may be used. Further, the output pattern setting unit 222 generates an output pattern setting screen 300 corresponding to the received examination site and displays the output pattern setting screen 300 on the display device 173, and the inspection cross section to be output via the output pattern setting screen 300 is displayed. Settings may be accepted.
- each inspection section is configured by one or more slices
- the detection result display unit 223 is configured to display an outer frame in a range specified by all the slices of the output inspection section as the stack 420. May be.
- the detection result display unit 223 may be configured to display the stack 420 in a blinking manner.
- the detection result display unit 223 may be configured to switch between displaying and hiding the stack 420 according to an instruction from an operator or at a predetermined time interval.
- the detection result display unit 223 may be configured to display the stack 420 in a display manner that is different for each inspection section.
- the imaging position setting unit 220 further includes an adjustment unit 224 that adjusts the imaging position set by the detection result display unit, and the imaging unit 230 is configured to perform imaging of the adjusted imaging position. May be.
- the adjustment unit 224 displays an adjustment instruction button used to adjust the imaging position on the display device 173 together with the stack 420 displayed by the detection result display unit 223, and the imaging is performed via the adjustment instruction button. You may comprise so that adjustment of a position may be received.
- the adjustment instruction button may include a button for instructing a moving direction of the stack selected by an operator and a button for instructing the arrangement of the stack selected by the operator.
- the MRI apparatus 100 further includes an input device 174 that accepts an instruction from an operator, and the adjustment unit 224 displays the stack 420 according to an instruction from the operator to the stack 420 via the input device 174.
- the adjustment may be made by updating at least one of the position and number.
- the stack 420 is displayed at the desired imaging position detected by the automatic positioning unit 221 without hindering the visibility of the structure and tissue state of the positioning image behind. Is done. Therefore, it is easy to grasp the position of the imaging position on the positioning image, and it is easy to judge the correctness in relation to the positioning image behind.
- the mismatched portion is displayed with its display mode changed. Therefore, the operator can easily grasp the position actually used for the main imaging among the imaging positions detected by the automatic positioning unit 221. Since the operator can make an adjustment while seeing such a display, the adjustment work becomes easy. Therefore, according to the present embodiment, even when a portion having a plurality of inspection cross sections is an inspection target, the advantage of the automatic positioning function of shortening the positioning time is not impaired.
- the setting of the output pattern composed of the inspection cross section and the number of inspection cross sections corresponding to the inspection site is performed by a dedicated interface. Therefore, the operator can easily set an output pattern even if a part having a plurality of inspection sections is an inspection target.
- the present embodiment when the number of designated stacks specified by the imaging parameters is different from the number of output imaging positions set as the output pattern, adjustment of the output imaging position to which the stack 420 is assigned or the number of output imaging positions Adjustment such as increase / decrease is performed using a dedicated interface.
- the present embodiment since the present embodiment includes simple adjustment means with good operability, the adjustment work can be easily and easily performed and can be easily performed, and can be adjusted with high accuracy regardless of the operator. .
- the present embodiment it is possible to automatically output a positioning position suitable for an inspection purpose even when imaging a part having a plurality of positions that can be set as imaging positions. If it is not necessary to adjust the output position, the main imaging can be performed as it is. On the other hand, even when the output position needs to be adjusted, the adjustment can be performed intuitively and easily. Accordingly, the number of operations is reduced as a whole inspection, and the burden on the operator is reduced.
- an examination cross section is set in step S1002 according to the examination site, and a name is given and saved in step S1003.
- An output pattern may be created in advance for each selectable examination section and number of examination sections in accordance with the examination site, and a name may be assigned and registered in the data holding unit 240. That is, the MRI apparatus 100 further includes a data holding unit that holds in advance an examination section that can be selected for each examination site as an output pattern, and the output pattern setting unit 222 selects from the output patterns held in the data holding unit By accepting, the setting of the inspection section to be output may be accepted.
- the processing in steps S1002 and S1003 does not have to be performed. That is, when the examination site is set in step S1001, the imaging condition setting unit 210 goes to step S1004 and displays the protocol setting screen 500 on the display device 173. At this time, the protocol setting screen 500 is configured to accept selection of an output pattern when the setting for automatic positioning is accepted in the parameter setting area 520. Then, the imaging condition setting unit 210 displays the output pattern name of the output pattern created in advance on the menu display or the like, accepts the operator's selection, creates and saves the inspection protocol according to the accepted selection.
- the output pattern to be used may be configured to be changeable at an arbitrary timing.
- it may be configured to be changeable on the inspection screen 600 displayed in step S1005.
- the output pattern name can be selected by menu display or the like.
- the vertebral body was selected on the protocol setting screen 500, but can be changed to an intervertebral disc on the examination screen 600.
- the stack 420 is displayed with the changed output pattern.
- the output pattern may be changed after the stack 420 is displayed in step S1009.
- the process returns to step S1008, the automatic positioning unit 221 performs automatic positioning, and the detection result display unit 223 displays the stack 420 along the output pattern.
- the automatic positioning unit 221 can detect all the imaging positions of the examination target region, the process returns to step S1009 without performing automatic positioning again every time the output pattern is changed, and the detection result display unit 223 outputs What is necessary is just to change the imaging position to perform according to an output pattern.
- the output pattern setting unit 222 sets an output pattern, names it, and stores it. Then, the selection may be made on the protocol setting screen 500 or the inspection screen 600.
- the output pattern setting screen 300 need not be prepared. Then, for example, a menu for selecting an inspection section may be arranged on the inspection screen 600 or the protocol setting screen 500 so that the menu can be selected there.
- FIG. 11 illustrates a case where the inspection screen 600 includes a menu 621 for selecting an inspection section. In this case, the operator selects an inspection section when selecting each imaging parameter.
- the detection result display unit 223 displays the stack 420 according to the selection.
- the number of detected items cannot be selected. Therefore, in the case of an examination section having a plurality of imaging positions, the number of designated stacks set by the imaging parameters may be set as the number of detections. Further, the stack 420 may be displayed at all the imaging positions, and the selection by the operator may be received from the stack 420.
- timing of output pattern setting is not limited to the above.
- after acquiring a scanogram image after acquiring an image by each main imaging, and the like may be used. That is, the next inspection cross section is determined by looking at the obtained image.
- an activation button 622 for invoking the output pattern setting screen 300 is arranged in the imaging parameter setting portion of the inspection screen 600 that displays an image obtained after each imaging.
- the imaging condition setting unit 210 accepts pressing of the start button 622 and displays the output pattern setting screen 300.
- Fig. 13 shows an example of an output pattern setting screen 300 when the examination site is a knee joint.
- the knee joint has cross sections such as meniscus and cruciate ligament.
- an output imaging position is not specified by an inspection section name, but a desired one as an automatic positioning output is selected from basic positioning positions set in advance according to the purpose of inspection. A case will be described as an example.
- the basic positioning position is set in advance as a default inspection section for each apparatus in accordance with the purpose of inspection, and is registered in the data holding unit 240. Then, the output pattern setting unit 222 sets an output pattern for each subject based on this default examination section.
- the inspection section setting area 311 displays the name assigned to each default inspection section. Here, default 1 and default 2 are assumed.
- the output pattern setting unit 222 extracts the positioning position (default 1) 321 registered in association with the name to the data holding unit 240 and places it on the standard image in the detection number setting area 312. indicate.
- the operator changes the displayed positioning position 321 by operating the input device 174 to determine the positioning position 322.
- the output pattern setting unit 222 outputs a positioning position 322 displayed on the standard image at that time as an output pattern when a name is input to the output pattern name setting area 320 and the save button 330 is pressed. It is registered in the data holding unit 240 in association with the pattern name.
- an output pattern created by the operator using the output pattern setting screen 300 can be selected in addition to the default inspection section.
- An example of an inspection screen 600 configured to be selectable is shown in FIG.
- FIG. 15 shows a specific example of the stack 420 display when the examination site is a knee joint.
- FIG. 15A shows an example of the stack 420 in which the display of a plurality of slices constituting the examination section is omitted at the output imaging position on the positioning image 410, and only the imaging range is displayed with a rectangle 421.
- FIG. 15B is an example in which the stack 420 is displayed in a blinking manner at the output imaging position on the positioning image 410.
- FIG. 15 (c) is an example of changing display / non-display of the stack 420 in accordance with an instruction from the operator.
- FIG. 16 shows an example of an output pattern setting screen 300 when the examination site is a shoulder joint. Also in the case where the examination site is the shoulder joint, as in the case of the knee joint, a case where a default examination cross section is created in advance for each apparatus, is given a name, and is registered in the data holding unit 240 is exemplified. Other processing is the same as that for the knee joint.
- the name assigned to each default inspection section is displayed in the inspection section setting area 311.
- default 1 and default 2 are assumed.
- the output pattern setting unit 222 extracts the positioning position (default 1) 321 registered in association with the name to the data holding unit 240 and places it on the standard image in the detection number setting area 312. indicate.
- the operator changes the displayed positioning position 321 by operating the input device 174 to determine the positioning position 322.
- the output pattern setting unit 222 outputs a positioning position 322 displayed on the standard image at that time as an output pattern when a name is input to the output pattern name setting area 320 and the save button 330 is pressed. It is registered in the data holding unit 240 in association with the pattern name.
- FIG. 17 shows a specific example of the stack 420 display when the examination site is a shoulder joint.
- FIG. 17 (a) is an example of a stack 420 in which the display of a plurality of slices constituting the examination section is omitted at the output imaging position on the positioning image 410, and only the imaging range is displayed with a rectangle 421.
- FIG. 17B is an example in which the stack 420 is displayed blinking at the output imaging position on the positioning image 410.
- FIG. 17 (c) is an example of changing display / non-display of the stack 420 in accordance with an instruction from the operator.
- the MRI apparatus of the present embodiment has basically the same configuration as the MRI apparatus 100 of the first embodiment. However, in the present embodiment, as described above, after the automatic positioning according to the set output pattern, selection of the output imaging position to be displayed as a stack is received from the imaging positions of the obtained examination sections. For this reason, the configuration of the imaging position setting unit 220 of the control processing system 170 is different. Hereinafter, the present embodiment will be described focusing on the configuration different from the first embodiment.
- FIG. 18 is a functional block diagram of the imaging position setting unit 220 of the present embodiment.
- the present embodiment includes an automatic positioning unit 221, an output pattern setting unit 222, a detection result display unit 223, and an adjustment unit 224, as in the first embodiment.
- the detection result display unit 223 includes a selection receiving unit 225 that receives selection of an output imaging position for displaying the stack 420 from the imaging positions of the set examination sections.
- the functions of the automatic positioning unit 221, the output pattern setting unit 222, and the adjustment unit 224 are the same as those in the first embodiment.
- the detection result display unit 223 of the present embodiment will be described.
- the detection result display unit 223 of the present embodiment displays the set imaging position of the inspection cross section on the positioning image when the automatic positioning unit 221 performs the positioning process, as in the first embodiment.
- the display performed at this time is not the stack 420 but a simple display (hereinafter referred to as simple display).
- the simple display is performed in such a manner that the visibility of the positioning image is not impaired and the operator can grasp the position and inclination of the inspection section.
- the detection result display unit 223 generates, for example, a detection result display screen and displays it on the display device 173. Then, the detection result display unit 223 of the present embodiment performs simple display at the imaging position of the set inspection section on the positioning image 410 on the detection result display screen, and selects the imaging position for displaying the stack 420. Accept. Selection of the imaging position for displaying the stack 420 is received by the selection receiving unit 225 as described later.
- FIG. 19 shows an example of the detection result display screen 400a displayed by the detection result display unit 223 of the present embodiment.
- the detection result display screen 400a of this embodiment is generated by the imaging position setting unit 220 or the detection result display unit 223 using the data held in the data holding unit 240, and is displayed on the display device 173. Is displayed.
- the detection result display screen 400a includes a display area 401 for displaying the positioning image 410, an adjustment instruction area 430 for displaying various buttons used for adjusting the output imaging position, and the determination of the output imaging position.
- An imaging start button 440 that accepts an intention and an instruction to start imaging is provided. Each of these functions is the same as the function of the same name on the detection result display screen 400 of the first embodiment.
- the detection result display screen 400a of the present embodiment includes a confirmation button 470 that accepts an intention to confirm selection of an imaging position for displaying the stack 420.
- FIG. 20 is a diagram for explaining processing by the detection result display unit 223 and the selection reception unit 225 of the present embodiment.
- a case where the spine region is selected as the examination site and the vertebral body is selected as the examination section will be described as an example.
- a cross-section of the spine is displayed as the positioning image 410.
- FIG. 20 (a) is a diagram showing a display example by the detection result display unit 223 of the present embodiment.
- FIG. 20 (b) is a diagram for explaining how the selection accepting unit 225 accepts an operator's selection.
- FIG. 20 (c) is a diagram for explaining the stack 420 displayed on the positioning image 410.
- the simple display 450 is displayed at the imaging position of the set inspection section on the positioning image 410 in the display area 401.
- a specific example of the display is shown in FIG. FIG. 20A shows an example in which an arrow head is used as the simple display 450.
- the image pickup position at which the tip position of the arrow head is detected, and the inclination indicates the inclination of the detected inspection section.
- the display mode of the simple display 450 is not limited to this.
- the selection receiving unit 225 of the present embodiment receives the selection of the output imaging position by the operator on the positioning image 410 on which the simple display 450 is displayed. For example, as shown in FIG. 20B, the selection is accepted by surrounding a desired simplified display 450 with a rectangular region selection frame 460 using the input device 174. The release of the selection is accepted, for example, by placing the mouse pointer on the displayed area selection frame 460 and clicking.
- the method for selecting and canceling the simple display 450 is not limited to this.
- the selection receiving unit 225 determines that the simple display 450 (imaging position) surrounded by the rectangular area selection frame 460 has been selected at that time.
- the detection result display unit 223 When the detection result display unit 223 receives the notification of the selected simple display 450 (imaging position) from the selection reception unit 225, the detection result display unit 223 displays the position of the selected simple display 450 (imaging position) on the positioning image 410 in FIG. As shown in c), the stack 420 is displayed.
- the flow of inspection by each function of the control processing system 170 of this embodiment is basically the same as the processing flow of the first embodiment shown in FIG. However, a new process starts after the automatic positioning in step S1008 and before the stack display process in step S1009.
- the detection result display unit 223 sets the imaging position corresponding to the inspection section as the output imaging position, and displays the position on the positioning image 410.
- the stack 420 is displayed at the corresponding position of.
- the imaging position selected by the operator from the detected imaging positions is set as the output imaging position, and the stack 420 is displayed there.
- FIG. 21 shows the flow of processing up to the stack display processing in step S1009 after the automatic positioning processing in step S1008 of this embodiment.
- the display on the positioning image 410 at the time of each process will be described with reference to FIG.
- the examination site is a spinal region and the examination section is an intervertebral disc is shown.
- the detection result display unit 223 displays the imaging position of the set inspection section on the positioning image 410, as shown in FIG. A simple display 450 is displayed (step S2001).
- the selection receiving unit 225 receives selection of the simple display 450 from the operator (step S2002). As shown in FIG. 22 (b), the selection is made by surrounding the simplified display 450 of the position to be selected with a rectangular area selection frame 460.
- the selection receiving unit 225 receives pressing of the confirm button 470 (step S2003)
- the selected simple display 450 (imaging position) at that time is determined as the selected imaging position (step S2004) and detected.
- the result display unit 223 is notified.
- the detection result display unit 223 uses the selected imaging position as the output imaging position, and displays a stack 420 as shown in FIG. 22C at a position corresponding to the output imaging position on the positioning image 410. Processing is performed (step S2005).
- the stack display process using the output imaging position of the present embodiment determined in step S2005 is the same as the stack display process of the first embodiment shown in FIG. 8B. Further, the processing after the stack display S1009 is basically the same as that of the first embodiment. That is, as in the first embodiment, the adjustment unit 224 receives an adjustment to the output imaging position where the stack 420 is displayed, and the imaging position setting unit 220 receives an instruction to start imaging with the imaging start button 440. The output imaging position where the stack 420 is displayed at the time is set as the imaging position of the main imaging. All the data being processed is held in the data holding unit 240 constructed on the storage device 172.
- the MRI apparatus 100 of the present embodiment is the MRI apparatus 100 including the control processing system 170 and the display device 173 that perform control and calculation of the operation of the entire apparatus, and the control processing system 170 includes: An imaging condition setting unit 210 that accepts settings for executing an inspection, an imaging position setting unit 220 that sets an imaging position, and an imaging unit 230 that performs imaging at the imaging position set by the imaging position setting unit 220.
- the imaging position setting unit 220 includes an automatic positioning unit 221 that detects the positions of all examination sections of the examination site received by the imaging condition setting unit 220 on a scanogram image acquired in advance, and the display device 173 While displaying the scanogram image, one or more predetermined positions among the positions detected by the automatic positioning unit 221 are set as the imaging position, and visibility is ensured at the imaging position on the scanogram image.
- the detection result display unit 223 may include a selection receiving unit 225 that receives selection of a position set as the imaging position.
- the MRI apparatus 100 further includes an input device 174 that accepts an input from an operator, and the detection result display unit 223 displays a simple display 450 at a position detected by the automatic positioning unit 221 on the scanogram image.
- the selection receiving unit 225 receives the selection of the position by receiving the selection of the simple display 450 via the input device 174, and the simple display 450 does not impair the visibility of the scanogram image. And it is good also as a display which can grasp
- the imaging position setting unit 220 further includes an output pattern setting unit 222 that sets the inspection section set as the imaging position as an output pattern
- the detection result display unit 223 includes the automatic image on the scanogram image.
- the simplified display 450 is performed at the position of the inspection cross section set as the output pattern
- the selection receiving unit 225 selects the simplified display 450 via the input device 174.
- the simple display 450 may be a display that does not impair the visibility of the scanogram image and can grasp the position and inclination of the detected inspection section.
- the MRI apparatus of this embodiment basically has the same configuration as that of the first embodiment. Therefore, the same effects as those of the first embodiment are obtained. Furthermore, in the MRI apparatus of this embodiment, the operator can select a desired imaging position from the imaging positions detected by the automatic positioning unit 221. Therefore, according to the present embodiment, it is possible to provide an MRI apparatus that is more user-friendly and has high operability for determining the imaging position.
- inspection section in the case of a spinal region, a vertebral body or an intervertebral disc
- a plurality of inspection sections may be set.
- the detection result display unit 223 performs a simple display 450 at the imaging positions of all detected cross sections.
- a case where a spinal region is selected as an examination site is illustrated.
- the examination cross section includes a vertebral body and an intervertebral disc. Therefore, the automatic positioning unit 221 detects the imaging positions of all examination sections, that is, the entire imaging positions of the vertebral body and the intervertebral disc. First, the detection result display unit 223 performs a simple display 450 at the imaging positions of both the vertebral body and the intervertebral disc as shown in FIG. At this time, as shown in the figure, the simplified display 450 may be performed in a different manner for each inspection section.
- the different modes include, for example, changing the display position, changing the display form, and the like.
- a simple display 452 of the output imaging position corresponding to the intervertebral disc is displayed on the left side of the spine
- a simple display 451 of the output imaging position corresponding to the vertebral body is displayed on the right side of the spine
- the simple display 451 and the simple display 452 are An example of changing the display color is also shown.
- the desired imaging position is selected in the same manner as described above by using a region selection frame 460 such as a rectangle as shown in FIG. 23 (b). It is done by the method of enclosing. Then, as shown in FIG. 23 (c), the detection result display unit 223 displays the stack 420 at the position of the selected simple display 450 regardless of the inspection cross section type.
- the detection result display unit 223 specifies the position and inclination of the inspection cross section as the imaging position, and the position on the positioning image 410.
- a simple display 450 of an aspect in which the operator can grasp the structure of the examination site and the state of the tissue is displayed, and the selection receiving unit 225 receives the selection of the output imaging position via the simple display.
- a simple display 450 corresponding to a desired position may be selected in a region selection frame 460 having other shapes, for example, a circle shown in FIG. 24A, an ellipse, a polygon, or the like. Further, as shown in FIG. 24 (b), a plurality of areas may be selected. In this case, the stack 420 is displayed at the positions of all the simple displays 450 selected when the confirmation button 470 is pressed. Furthermore, the simple display 450 itself at a desired position may be selected by an operation such as clicking the mouse pointer.
- the selected simple display 450 may be displayed in a different form from the non-selected simple display 450.
- Different modes include, for example, changing the display color as shown in FIG.
- an arrow head is used as the simple display 450, for example, the thickness and shape of the outer frame line may be changed.
- the simple display 450 is configured to be performed at a predetermined imaging position detected by the automatic positioning unit 221.
- the simple display 450 may not be performed.
- the flow of the stack display process in this case will be described with reference to FIG.
- only the positioning image 410 is extracted and described, taking as an example the case where the spinal region is selected as the examination site and the vertebral body is selected as the examination section.
- the detection result display unit 223 does not perform the simplified display 450 in step S2001 as shown in FIG. 25 (a). However, the position information of the imaging position of the set inspection section is held internally as shown in FIG.
- the selection accepting unit 225 accepts selection of a region on the positioning image 410 without the simple display 450 as shown in FIG. 24 (c).
- the selection receiving unit 225 In response to pressing of the confirm button 470, the selection receiving unit 225 notifies the detection result display unit 223 of the selected area.
- the detection result display unit 223 determines the imaging position of the set inspection section in the selected area as the selected imaging position and sets it as the output imaging position.
- the detection result display unit 223 displays the stack 420 at the output imaging position on the positioning image 410 as shown in FIG.
- FIGS. 26A to 26D show the state of the positioning image 410 during the stack display process in this case.
- FIGS. 26A to 26D show the state of the positioning image 410 during the stack display process in this case.
- the region selection method is not limited to the rectangular region selection frame 460.
- an area selection frame 460 having another shape may be used.
- FIG. 28 (a) shows an example in which the operator designates a selection area with an elliptical frame.
- FIG. 28 (b) shows an example in which the operator designates a selection area using polygons.
- a region to be selected may be designated by a method such as drawing a line 461 that designates a selection range.
- the detection result display unit 223 sets the output imaging position within the range of the body axis direction coordinates (coordinate values) of the both ends of the line 461 as the selected output imaging position, and sets the stack 420. indicate.
- the MRI apparatus of this modification includes the input device 174 that receives an input from an operator, and the selection receiving unit 225 receives a selection of an area on the scanogram image via the input device 174.
- the position in the selected area among the positions detected by the automatic positioning unit 221 is set as the selected position.
- the imaging position setting unit 220 further includes an output pattern setting unit 222 that sets the inspection section to be set as the imaging position as an output pattern, and the selection receiving unit 225 receives the input via the input device 174.
- Accepts selection of an area on a scanogram image, and is the position of the inspection cross section set as the output pattern in the position detected by the automatic positioning unit 221 and the position in the selected area is selected. You may comprise so that it may become a position. For this reason, since the simple display 450 is not made, the operator can select the imaging region in a state where there is nothing that hinders the visibility of the positioning image 410. Therefore, according to this modification, higher operability can be obtained.
- the number of slices may be increased or decreased. That is, when each inspection section is composed of one or more slices, the adjustment unit 224 accepts a change in the number of slices of the inspection section in accordance with an instruction from the operator to the stack 420. This processing is performed by the adjustment unit 224.
- this method will be described with reference to FIG.
- the case where the examination site is the spinal region and the vertebral body and the intervertebral disc are selected as the examination cross section is illustrated. The same applies to the case where only one inspection cross section is selected and no inspection cross section is selected.
- the selection receiving unit 225 performs the operation Accept a selection from a person.
- the simple display 450 by the arrow head displayed at a desired position is selected with a mouse or the like and one simple display 450 is selected is illustrated, but as described in the above example of the present embodiment, You may comprise so that an area
- the detection result display unit 223 displays the stack 420 at the imaging position within the accepted selection range, as shown in FIG. 29 (b).
- the stack 420 to be displayed is displayed in parallel with the detected inspection section at the selected imaging position.
- the stack 420 is displayed in a manner in which it is understood that there are a plurality of slices. For example, it is desirable to display a line having the number of slices set in advance by the imaging parameter at a slice interval set by the imaging parameter.
- the adjustment unit 224 accepts an instruction to increase or decrease the number of slices in addition to the fine adjustment of the imaging position described in the first embodiment.
- the instruction is performed by, for example, a method of enlarging the stack 420 in the direction in which the number of slices is to be increased by a drag operation until the number of slices to be increased is reached. At this time, the angle of the stack 420 is fixed.
- the adjustment unit 224 receives such an instruction from the operator and calculates the number of slices from the slice interval set by the imaging parameter and the size of the enlarged stack 420 in the slice direction. Further, each imaging slice position is calculated from the information on the detection position (imaging position), the number of slices, and the slice interval. At this time, the number of slices may be displayed as a numerical value.
- the number of slices is increased or decreased within a range that does not overlap with the adjacent stack 420.
- the adjustment unit 224 further receives an instruction to change the number of slices at the selected output imaging position, further adjusts the number of slices according to the received instruction, and the detection result
- the display unit 223 displays the stack 420 at the adjusted output imaging position.
- the operator can perform multi-slice imaging in accordance with the detection angle of the imaging position by selecting the imaging position at a desired angle. Therefore, higher operability can be obtained.
- the adjustment unit 224 receives the parameter change, and displays the stack 420 with the number of slices and the slice interval specified by the changed parameter.
- the adjustment of the slice interval can also be accepted, and the operator can easily adjust the slice interval.
- the adjustment of the slice interval may be accepted by changing the parameter.
- the function of the imaging position setting unit 220 is described as being included in the control processing system 170 of the MRI apparatus 100, but is not limited thereto.
- the information processing apparatus may be constructed on an information processing apparatus that can transmit and receive data to and from the MRI apparatus 100 and is independent of the MRI apparatus 100.
- the MRI apparatus has been described as an example.
- the imaging position setting method of each embodiment can be applied to a general medical image imaging apparatus that sets an imaging slice position and performs imaging.
- 100 MRI apparatus 101 subject, 120 static magnetic field generation system, 130 gradient magnetic field generation system, 131 gradient magnetic field coil, 132 gradient magnetic field power supply, 140 sequencer, 150 transmission system, 151 transmission coil, 152 high frequency oscillator, 153 modulator, 154 High-frequency amplifier, 160 reception system, 161 reception coil, 162 signal amplifier, 163 quadrature detector, 164 A / D converter, 170 control processing system, 171 CPU, 172 storage device, 173 display device, 174 input device, 210 imaging Condition setting unit, 220 imaging position setting unit, 221 automatic positioning unit, 222 output pattern setting unit, 223 detection result display unit, 224 adjustment unit, 225 selection accepting unit, 230 imaging unit, 240 data holding unit, 300 output pattern setting screen , 310 Output pattern setting area, 311 Inspection section setting area, 312 Detection number setting area, 320 Output pattern name setting area, 321 Default positioning position, 322 Positioning position , 330 save button, 400 detection result display screen, 400a detection result display screen, 401
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Abstract
Description
本発明の磁気共鳴イメージング装置は、装置全体の動作の制御と演算とを行う制御処理系および表示装置を備える磁気共鳴イメージング装置であって、前記制御処理系は、検査を実行するための設定を受け付ける撮像条件設定部と、撮像位置を設定する撮像位置設定部と、前記撮像位置設定部が設定した撮像位置の撮像を行う撮像部と、を備え、前記撮像位置設定部は、予め取得したスキャノグラム画像上で、前記撮像条件設定部が受け付けた検査部位の全検査断面の位置を検出する自動位置決め部と、前記表示装置に、前記スキャノグラム画像を表示するとともに、前記自動位置決め部が検出した位置の中の予め定めた1以上の位置を前記撮像位置に設定し、当該スキャノグラム画像上の当該撮像位置にスタックを表示する検出結果表示部と、を備えることを特徴とする。
また、前記検出結果表示部は、操作者からの指示に従って、または、予め定めた時間間隔で、前記スタックの表示と非表示とを切り替えることを特徴とする。
また、操作者からの入力を受け付ける入力装置をさらに備え、前記検出結果表示部は、前記スキャノグラム画像上の、前記自動位置決め部が検出した位置に簡易表示を行い、前記選択受付部は、前記入力装置を介して、前記簡易表示の選択を受け付けることにより、前記位置の選択を受け付け、前記簡易表示は、前記スキャノグラム画像の視認性を損なわず、かつ、前記検出した検査断面の位置と傾きとを把握可能な表示とすることを特徴とする。
また、前記各検査断面は1以上のスライスで構成され、前記調整部は、前記スタックに対する操作者による指示に従って、前記検査断面のスライス数の変更を受け付けることを特徴とする。
以下、本発明を適用する第一の実施形態について説明する。以下、本発明の実施形態を説明するための全図において、同一機能を有するものは同一符号を付し、その繰り返しの説明は省略する。
本実施形態の制御処理系170は、以上の手順で検査を実行する。
Claims (19)
- 装置全体の動作の制御と演算とを行う制御処理系および表示装置を備える磁気共鳴イメージング装置であって、
前記制御処理系は、検査を実行するための設定を受け付ける撮像条件設定部と、撮像位置を設定する撮像位置設定部と、前記撮像位置設定部が設定した撮像位置の撮像を行う撮像部と、を備え、前記撮像位置設定部は、予め取得したスキャノグラム画像上で、前記撮像条件設定部が受け付けた検査部位の全ての検査断面の位置を検出する自動位置決め部と、前記表示装置に、前記スキャノグラム画像を表示するとともに、前記自動位置決め部が検出した位置の中の予め定めた1以上の位置を前記撮像位置に設定し、当該スキャノグラム画像上の当該撮像位置にスタックを表示する検出結果表示部と、を備えることを特徴とする磁気共鳴イメージング装置。 - 請求項1記載の磁気共鳴イメージング装置であって、
前記撮像位置設定部は、前記撮像位置として設定する前記検査断面を出力パターンとして設定する出力パターン設定部をさらに備え、前記予め定めた1以上の位置は、前記自動位置決め部が検出した位置の中の、前記出力パターンとして設定された検査断面の位置であることを特徴とする磁気共鳴イメージング装置。 - 請求項2記載の磁気共鳴イメージング装置であって、
前記出力パターン設定部は、前記受け付けた検査部位に応じた出力パターン設定画面を生成して前記表示装置に表示し、当該出力パターン設定画面を介して前記出力する検査断面の設定を受け付けることを特徴とする磁気共鳴イメージング装置。 - 請求項2記載の磁気共鳴イメージング装置であって、
検査部位毎に選択可能な検査断面を予め出力パターンとして保持するデータ保持部をさらに備え、前記出力パターン設定部は、前記データ保持部に保持される出力パターンから選択を受け付けることにより、前記出力する検査断面の設定を受け付けることを特徴とする磁気共鳴イメージング装置。 - 請求項1記載の磁気共鳴イメージング装置であって、
各検査断面は1以上のスライスで構成され、前記検出結果表示部は、前記スタックとして、各前記出力する検査断面の全スライスで特定される範囲の外枠を表示することを特徴とする磁気共鳴イメージング装置。 - 請求項1記載の磁気共鳴イメージング装置であって、
前記検出結果表示部は、前記スタックを点滅表示することを特徴とする磁気共鳴イメージング装置。 - 請求項1記載の磁気共鳴イメージング装置であって、
前記検出結果表示部は、操作者からの指示に従って、または、予め定めた時間間隔で、前記スタックの表示と非表示とを切り替えることを特徴とする磁気共鳴イメージング装置。 - 請求項2記載の磁気共鳴イメージング装置であって、
前記出力パターンとして設定される検査断面は複数あり、前記検出結果表示部は、検査断面毎に異なる表示態様で、前記スタックを表示することを特徴とする磁気共鳴イメージング装置。 - 請求項1記載の磁気共鳴イメージング装置であって、
前記検出結果表示部は、前記撮像位置として設定する位置の選択を受け付ける選択受付部を備えることを特徴とする磁気共鳴イメージング装置。 - 請求項9記載の磁気共鳴イメージング装置であって、
操作者からの入力を受け付ける入力装置をさらに備え、前記検出結果表示部は、前記スキャノグラム画像上の、前記自動位置決め部が検出した位置に簡易表示を行い、前記選択受付部は、前記入力装置を介して、前記簡易表示の選択を受け付けることにより、前記位置の選択を受け付け、前記簡易表示は、前記スキャノグラム画像の視認性を損なわず、かつ、前記検出した検査断面の位置と傾きとを把握可能な表示とすることを特徴とする磁気共鳴イメージング装置。 - 請求項10記載の磁気共鳴イメージング装置であって、
前記撮像位置設定部は、前記撮像位置として設定する前記検査断面を出力パターンとして設定する出力パターン設定部をさらに備え、前記検出結果表示部は、前記スキャノグラム画像上の、前記自動位置決め部が検出した位置の中の、前記出力パターンとして設定された検査断面の位置に簡易表示を行い、前記選択受付部は、前記入力装置を介して、前記簡易表示の選択を受け付けることにより、前記位置の選択を受け付け、前記簡易表示は、前記スキャノグラム画像の視認性を損なわず、かつ、前記検出した検査断面の位置と傾きとを把握可能な表示とすることを特徴とする磁気共鳴イメージング装置。 - 請求項9記載の磁気共鳴イメージング装置であって、
操作者からの入力を受け付ける入力装置をさらに備え、前記選択受付部は、前記入力装置を介して、前記スキャノグラム画像上の領域の選択を受け付け、前記自動位置決め部が検出した位置の中の前記選択された領域内の位置を、前記選択された位置とすることを特徴とする磁気共鳴イメージング装置。 - 請求項12記載の磁気共鳴イメージング装置であって、
前記撮像位置設定部は、前記撮像位置として設定する前記検査断面を出力パターンとして設定する出力パターン設定部をさらに備え、前記選択受付部は、前記入力装置を介して、前記スキャノグラム画像上の領域の選択を受け付け、前記自動位置決め部が検出した位置の中の前記出力パターンとして設定された検査断面の位置であって、前記選択された領域内の位置を、前記選択された位置とすることを特徴とする磁気共鳴イメージング装置。 - 請求項1記載の磁気共鳴イメージング装置であって、
前記撮像位置設定部は、前記検出結果表示部が設定した撮像位置の調整を行う調整部をさらに備え、前記撮像部は、前記調整後の撮像位置の撮像を行うことを特徴とする磁気共鳴イメージング装置。 - 請求項14記載の磁気共鳴イメージング装置であって、
前記調整部は、前記検出結果表示部が表示するスタックとともに、前記表示装置に前記撮像位置の調整に用いる調整指示ボタンを表示し、当該調整指示ボタンを介して前記撮像位置の調整を受け付けることを特徴とする磁気共鳴イメージング装置。 - 請求項14記載の磁気共鳴イメージング装置であって、
操作者からの指示を受け付ける入力装置をさらに備え、前記調整部は、前記入力装置を介した前記スタックに対する操作者からの指示に従って、前記スタックの表示位置および数の少なくとも1つを更新することにより、調整を行うことを特徴とする磁気共鳴イメージング装置。 - 請求項14記載の磁気共鳴イメージング装置であって、
前記各検査断面は1以上のスライスで構成され、前記調整部は、前記スタックに対する操作者による指示に従って、前記検査断面のスライス数の変更を受け付けることを特徴とする磁気共鳴イメージング装置。 - 請求項15記載の磁気共鳴イメージング装置であって、
前記調整指示ボタンは、操作者により選択された前記スタックの移動方向を指示するボタンと、操作者により選択された前記スタックの配置を指示するボタンと、を備えることを特徴とする磁気共鳴イメージング装置。 - 装置全体の動作の制御と演算とを行う制御処理系を備える磁気共鳴イメージング装置における、検査断面を複数有する検査部位の撮像位置の設定を支援する撮像位置設定支援方法であって、
前記制御処理系が、予め取得したスキャノグラム画像上で、前記検査部位の全検査断面の位置を検出する自動位置決めステップと、前記制御処理系が、前記検出した位置の中の予め定めた1以上の位置を前記撮像位置として設定し、前記スキャノグラム画像の当該撮像位置にスタックを表示する検出結果表示ステップと、を備えることを特徴とする撮像位置設定支援方法。
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KR20150103379A (ko) * | 2013-01-04 | 2015-09-10 | 디퍼이 신테스 프로덕츠, 인코포레이티드 | 골 임플란트를 설계 및 제조하기 위한 방법 |
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Also Published As
Publication number | Publication date |
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CN103596495B (zh) | 2016-11-02 |
US20140132268A1 (en) | 2014-05-15 |
CN103596495A (zh) | 2014-02-19 |
JPWO2012176886A1 (ja) | 2015-02-23 |
JP5960136B2 (ja) | 2016-08-02 |
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