WO2012133289A1 - Non-combustion suction type tobacco product - Google Patents

Non-combustion suction type tobacco product Download PDF

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Publication number
WO2012133289A1
WO2012133289A1 PCT/JP2012/057726 JP2012057726W WO2012133289A1 WO 2012133289 A1 WO2012133289 A1 WO 2012133289A1 JP 2012057726 W JP2012057726 W JP 2012057726W WO 2012133289 A1 WO2012133289 A1 WO 2012133289A1
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WO
WIPO (PCT)
Prior art keywords
tobacco
stabilizer
less
tobacco product
suction type
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PCT/JP2012/057726
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French (fr)
Japanese (ja)
Inventor
松本　光史
雄史 新川
敦郎 山田
片山　和彦
山田　学
Original Assignee
日本たばこ産業株式会社
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46931007&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2012133289(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 日本たばこ産業株式会社 filed Critical 日本たばこ産業株式会社
Priority to RU2013138739/12A priority Critical patent/RU2544152C1/en
Priority to EP12764151.2A priority patent/EP2647299B1/en
Priority to JP2013507554A priority patent/JP5489190B2/en
Priority to ES12764151T priority patent/ES2735537T3/en
Priority to CN201280008764.4A priority patent/CN103369980B/en
Publication of WO2012133289A1 publication Critical patent/WO2012133289A1/en
Priority to US13/926,076 priority patent/US20130284193A1/en

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    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00—Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/12—Chemical features of tobacco products or tobacco substitutes of reconstituted tobacco
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
    • A24F42/20—Devices without heating means
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/20—Devices using solid inhalable precursors

Definitions

  • the present invention relates to a non-combustion suction type tobacco product that eliminates the generation of smoke associated with ignition.
  • This type of non-combustion suction type tobacco product includes a hollow suction holder and a packing of tobacco particles obtained by granulating the tobacco raw material and having a ventilation resistance of about 40 to about 80 mmHg.
  • a ventilation resistance of about 40 to about 80 mmHg.
  • the amount of nicotine released from tobacco particles decreases relatively rapidly as the number of puffs increases. This means that as the number of puffs increases, the nicotine sucked by the user changes greatly. This not only gives the user a sense of incongruity when using the suction, but also allows the user to use a usable period (the number of puffs). ) Feels shorter (less) than expected.
  • the present invention has been made based on the above-mentioned circumstances, and the object of the present invention is to stabilize the delivery amount of nicotine, which is one of tobacco-specific components, over a long period of time, greatly increasing the number of puffs satisfied by the user. It is to provide a non-combustion suction type tobacco product that can be increased.
  • This non-combustion suction type tobacco product stabilizes the tobacco granules obtained by cutting or crushing tobacco raw materials and the delivery of nicotine from the granules. At least one stabilizer that has a solubility parameter distance with nicotine of 17 or less and a vapor pressure at 25 ° C. of 1 mmHg or less.
  • the stabilizer is selected from propylene glycol, benzyl alcohol, or a compound having an ester group, which includes medium chain fatty acid triglycerides, citric acid triesters (triethyl citrate, tributyl citrate, etc.), benzyl benzoate and lauric acid. Selected from ethyl acid.
  • the stabilizer preferably has a characteristic that the distance between solubility parameters is 12 or less and the vapor pressure at 25 ° C. is 0.1 mmHg or less.
  • the tobacco particulates can further include an additive composed of at least one of a carbonate and a bicarbonate generally used in snuff products such as snus.
  • the non-combustion suction type tobacco product may further include a heating source for heating the tobacco particulates.
  • the stabilizer has a characteristic that the distance between the solubility parameters is 17 or less and the vapor pressure becomes 1 mmHg or less at the heating temperature of the tobacco granular material.
  • the content of the stabilizer is preferably 5 to 20% by weight based on the dry matter weight of the source. In this case, if the content of the stabilizer is less than 5% by weight, the required stabilization of nicotine cannot be obtained. Conversely, if the content of the stabilizer is more than 20% by weight, the stabilizer becomes granular.
  • the agglomerates are agglomerated, making it difficult to handle tobacco granules, that is, to produce them.
  • the non-combustion suction type tobacco product of the present invention contains a stabilizer in the tobacco granules, the amount of nicotine, which is one of the components unique to tobacco released from the tobacco granules, can be stabilized over a long period of time. Can be made.
  • the non-combustion suction type tobacco product 1 of one embodiment shown in FIG. 1 includes an axis A, an upstream member 2, a tobacco cartridge 6, a downstream member 10, and a mouthpiece member 12 aligned along the axis A.
  • These members 2, 6, 10, 12 are integrally coupled by a plurality of connecting bolts / nuts 14.
  • the upstream member 2 is a 1 mm thick sheet made of stainless steel, and includes an opening region 16 in the central region.
  • the opening region 16 has an opening ratio of 23%.
  • the opening region 16 is formed by small holes having a diameter of 1 mm that are uniformly distributed.
  • the cigarette cartridge 6 includes a frame member 18 made of stainless steel and having a thickness of 2 mm.
  • the frame member 18 has an opening having an inner diameter of 26 mm at the center thereof.
  • Tobacco granules 20 are accommodated in the openings, and the tobacco granules 20 have air permeability.
  • the tobacco cartridge 6 further includes breathable nonwoven fabrics 4, 8 that sandwich the frame member 18 of the tobacco cartridge 6, and the tobacco particulates 20 fall off from the frame member 18. To prevent.
  • the tobacco granular material 20 will be described later.
  • the downstream member 10 is a 1 mm thick sheet made of stainless steel like the upstream member 2, and has an opening 22 having an inner diameter of 18 mm in the central region.
  • the mouthpiece member 12 is formed of Teflon (trademark) and includes a mouth end 24. The mouth end 24 protrudes from the face of the mouth member 12 opposite to the downstream member 10 and has an inner diameter of 6 mm.
  • the opening of the mouthpiece member 12 located on the downstream member 10 side has an inner diameter of 20 mm.
  • the external air flows from the opening region 16 of the upstream member 2 to the nonwoven fabric 4, the tobacco granular material 20, the nonwoven fabric 8, and the downstream. It flows into the user's mouth through the opening 22 of the member 10 and the mouthpiece member 12.
  • the air passes through the tobacco granule 20
  • the nicotine released from the tobacco granule 20 is included in the air, and thus the user sucks in air containing nicotine.
  • the tobacco granule 20 is made from a granule obtained by chopping or pulverizing a tobacco raw material made of domestically produced Burley leaf tobacco, followed by humidification and heat treatment, and, for example, at least one of carbonate and bicarbonate.
  • the granular material is contained in an amount of 300 mg by dry matter weight.
  • the mixture contains 12% by weight of additives based on the dry matter weight of the tobacco raw material, and nicotine, one of the tobacco-specific components contained in the granules, is 2.3% of the dry matter weight. %, And the volatile component contained in the granular material is adjusted to be 12% by weight of the weight of the granular material.
  • the content of nicotine was 200 mg ⁇ 2.5 mg granule added with 7.5 ml of 11 wt% sodium hydroxide aqueous solution and 10 ml of hexane, and shaken at room temperature for 60 minutes while shielding light with aluminum foil.
  • the hexane phase was obtained by analyzing with a gas chromatograph mass spectrometer.
  • the content of the volatile component is determined from the weight reduction of the granular material after 200 mg ⁇ 2 mg of the granular material is dried at 80 ° C. for 3 hours. Further, the dry matter weight is represented by a value obtained by subtracting the amount of the volatile component obtained as described above from the weight of the granular material.
  • the tobacco granule 20 includes, in addition to the above-mentioned mixture, at least one stabilizer that stabilizes the delivery amount of the nicotine to the user, and this stabilizer has a solubility parameter with nicotine.
  • the distance is 17 or less, preferably 12 or less, and the vapor pressure at 25 ° C. is 1 mmHg or less, preferably 0.1 mmHg or less.
  • the distance between solubility parameters is an index indicating the solubility of a solute in a solvent, and is generally represented by Ra (MPa 1/2 ), and Ra is obtained from the following equation.
  • Ra [4 * ( ⁇ d, 2- ⁇ d, 1) ⁇ 2 + ( ⁇ p, 2- ⁇ p, 1) ⁇ 2 + ( ⁇ h, 2- ⁇ h, 1) ⁇ 2] ⁇ (1/2)
  • ⁇ d, ⁇ p, and ⁇ h are defined as follows.
  • ⁇ d Dispersion force of solubility parameter
  • ⁇ p Dipolar interaction of solubility parameter
  • ⁇ h Hydrogen bond of solubility parameter
  • the stabilizer is selected from propylene glycol, benzyl alcohol, or a compound having an ester group, and as the compound, medium chain fatty acid triglyceride, citric acid triester (triethyl citrate, tributyl citrate, etc.), benzylbenzoate And ethyl laurate.
  • Table 1 shows the solubility parameter distance Ra of the stabilizer and the vapor pressure at 25 ° C. together with glycerin (A).
  • the stabilizer C is a medium-chain fatty acid triglyceride mainly composed of caprylic acid triglyceride, specifically, Coconut MT manufactured by Kao Corporation.
  • the distance Ra between the solubility parameters in Table 1 is a calculation result using Molecular Modeling Pro Version 6.01.
  • the measuring device shown in FIG. 2 is used. This measuring device is specific to the tobacco supplied from the tobacco product 1 to the user when the user sucks the tobacco product 1 described above. Measure the amount of nicotine delivered.
  • the measuring apparatus includes an impinger 26 containing 20 ml of ethanol.
  • an impinger 26 containing 20 ml of ethanol.
  • a Kinoshita gas absorption cleaning bottle (standard type 50 ml) manufactured by Kinoshita Rika Kogyo Co., Ltd. was used for the impinger 26.
  • the impinger 26 has filter particles (100 to 200 ⁇ m) inside thereof, and has a suction pipe 28 and a delivery pipe 30 respectively led out from the inside.
  • the tobacco product 1 to be verified can be connected to the suction pipe 28, while the delivery pipe 30 is connected to a suction pump 36 via an electromagnetic valve 32 and a mass flow controller (MFC) 34. Further, a valve controller (VC) 38 is electrically connected to the electromagnetic valve 32, and this valve controller 38 controls the opening / closing operation of the electromagnetic valve 32.
  • MFC mass flow controller
  • the solenoid valve 32 can repeat one suction cycle in which the impinger 26 is released to the atmosphere for 11 seconds after the suction pump 36 and the impinger 26 are connected for 4 seconds.
  • the flow rate of the mass flow controller 34 is set to 3300 cc / min.
  • a tobacco product of a first comparative example in which the tobacco granule 20 does not contain glycerin (A) or stabilizers B to H and a comparative example 2 in which the tobacco granule 20 contains glycerin (A)
  • Tobacco products and tobacco products of Examples each containing stabilizers B to H in tobacco granules 20 were prepared.
  • the contents of glycerin (A) and stabilizers B to F are each 15% by weight (45 mg) with respect to the dry matter weight of the tobacco granules 20. Then, after connecting one of the tobacco products of Comparative Examples 1 and 2 and the Example to the suction tube 28 of the impinger 26, the above suction cycle was repeated 50 times in an environment of room temperature 22 ° C. and humidity 60%, Nicotine delivered from the tobacco product was collected in ethanol in Impinger 26.
  • the ethanol from which the nicotine was collected was taken out from the impinger 26, the taken-out ethanol was analyzed with a gas chromatograph mass spectrometer, and tobacco-specific nicotine per one suction cycle (1 puff) from the tobacco product was measured.
  • the collection and analysis measurements described above were repeated until the total number of aspiration cycles reached a predetermined number of times, thereby completing the measurement process for one tobacco product. Such a measurement process is carried out for each tobacco product, and the measurement results are shown in FIGS.
  • the tobacco products of the examples containing the stabilizers G and H are different in the following points when compared with other examples.
  • nicotine contained in the granules was 1.6% by weight of the dry weight of the tobacco raw material, and the volatile components contained in the granules were 10% by weight of the granules.
  • the tobacco products of the examples containing stabilizers B to H are lower in the amount of nicotine delivered with the increase in the number of puffs than the tobacco products of comparative example 1 (without stabilizer). It can be seen that the stabilizers B to H are effective in stabilizing the delivery amount of nicotine over a long period of time.
  • the decrease in the amount of nicotine delivered with the increase in the number of puffs was not significantly changed compared to the tobacco product of Comparative Example 1 (without stabilizer). It is not effective in stabilizing the delivery amount.
  • the amount of nicotine delivered is lower than that of the tobacco product of Comparative Example 1 regardless of the number of puffs. This is because the trapping effect of nicotine by the stabilizer F (benzyl alcohol) is higher than that of the other stabilizers B to E, G and H. Therefore, when the stabilizer F is used, if the content of the stabilizer F is made lower than the contents of the stabilizers B to E, G, H, the tobacco product containing the stabilizer F is the tobacco of other examples. It is thought that nicotine can be delivered in the same way as the product. This point will become clear from the description of the measurement results in FIG.
  • the nicotine delivery amount tends to increase as the number of puffs increases.
  • the vapor at 25 ° C in the case of a stabilizer having a solubility parameter distance Ra of 12 or less, such as the stabilizer F, the vapor at 25 ° C.
  • the pressure is considered to be too high, and therefore it is desirable to select a stabilizer with a vapor pressure at 25 ° C. of 0.1 mmHg or less.
  • the content of the stabilizers B to H may be 5 wt% to 20 wt%. I understand that. Here, if the content is less than 5% by weight, a desired stabilizing effect cannot be obtained with respect to the delivery amount of nicotine. Conversely, if the content is more than 20% by weight, the stabilizer causes the tobacco granule 20 to be formed. Condensation makes handling of the tobacco granulate 20, ie its manufacture difficult.
  • the tobacco products containing the stabilizer F can be used as stabilizers B to E, G, It is expected that a similar amount of nicotine delivered by tobacco products containing H can be generated.
  • the non-combustion suction type tobacco product may include a heating source for heating the tobacco granules 20.
  • the upstream member 2 of the tobacco product contains an electrical heater 40.
  • the heater 40 heats the tobacco granular material 20 to a desired temperature via the upstream member 2, the nonwoven fabric 4 and the frame member 18 during use of the tobacco product.
  • the stabilizer contained in the tobacco granule 20 has a vapor pressure of 1 mmHg or less at the heating temperature of the tobacco granule 20 and a solubility parameter distance Ra with nicotine of 17 or less. More preferably, the stabilizer is selected from among stabilizers having such characteristics that the vapor pressure is 0.1 mmHg or less and the distance Ra between the solubility parameters is 12 or less at the heating temperature of the tobacco granule 20.
  • Table 2 shows the vapor pressures of glycerin (A) and the above-mentioned stabilizer at 25 ° C., 70 ° C. and 100 ° C., respectively.
  • the stabilizer is not limited to the stabilizers B to H described above as long as the stabilizer has a characteristic in which the distance Ra between the dissolution parameters is 17 or less and the vapor pressure at 25 ° C. is 1 mmHg or less.
  • B to H may be arbitrarily combined, and the structure of the tobacco product itself is not limited to that shown in FIG.
  • the heating temperature illustrated in Table 2 is selected.
  • the tobacco granular material 20 can be heated to an arbitrary temperature.
  • the heating method of the tobacco granular material 20 is not limited to the method illustrated in FIG.

Abstract

This non-combustion suction type tobacco product is characterized by containing tobacco granules (20) formed from leaf tobacco or other tobacco raw material and at least one type of stabilizer that stabilizes the delivery of nicotine from these tobacco granules (20), the distance between solubility parameters for this stabilizer and nicotine being 17 or less, and the vapor pressure of the stabilizer at 25°C being 1 mmHg or less.

Description

非燃焼吸引型たばこ製品Non-combustion suction tobacco products
　本発明は、着火に伴う煙の発生を無くした非燃焼吸引型たばこ製品に関する。 The present invention relates to a non-combustion suction type tobacco product that eliminates the generation of smoke associated with ignition.
　この種の非燃焼吸引型たばこ製品は中空の吸引ホルダと、この吸引ホルダ内に配置され、たばこ原料を粒状化して得たたばこ粒の充填体とを含み、約４０～約８０ｍｍＨｇの通気抵抗を提供する（特許文献１参照）。
　特許文献１によれば、その使用時、つまり、ユーザによる吸引時、たばこ特有の成分の１つであるニコチンが吸引空気とともにユーザの口腔内に送出される。 This type of non-combustion suction type tobacco product includes a hollow suction holder and a packing of tobacco particles obtained by granulating the tobacco raw material and having a ventilation resistance of about 40 to about 80 mmHg. Provided (see Patent Document 1).
According to Patent Document 1, at the time of use, that is, at the time of inhalation by the user, nicotine, which is one of the components unique to tobacco, is delivered into the user's oral cavity together with aspirated air.
国際公開第2010/095659号パンフレットInternational Publication No. 2010/095659 Pamphlet
　特許文献１の場合、たばこ粒からのニコチンの放出量、即ち、ユーザの口腔内へのニコチンの送出量はパフ回数の増加に伴い比較的速やかに減少する。このことはパフ回数の増加に伴い、ユーザが吸引するニコチンが大きく変化することを意味することから、吸引使用に際し、ユーザに違和感を与えてしまうばかりでなく、ユーザは使用可能な期間（パフ回数）が期待する以上に短い（少ない）と感じてしまう。 In the case of Patent Document 1, the amount of nicotine released from tobacco particles, that is, the amount of nicotine delivered into the user's oral cavity, decreases relatively rapidly as the number of puffs increases. This means that as the number of puffs increases, the nicotine sucked by the user changes greatly. This not only gives the user a sense of incongruity when using the suction, but also allows the user to use a usable period (the number of puffs). ) Feels shorter (less) than expected.
　本発明は上述の事情に基づいてなされたもので、その目的とするところはたばこ特有の成分の１つであるニコチンの送出量を長期に亘って安定させ、ユーザが満足するパフ回数を大幅に増加させることができる非燃焼吸引型たばこ製品を提供することにある。 The present invention has been made based on the above-mentioned circumstances, and the object of the present invention is to stabilize the delivery amount of nicotine, which is one of tobacco-specific components, over a long period of time, greatly increasing the number of puffs satisfied by the user. It is to provide a non-combustion suction type tobacco product that can be increased.
　上記目的は本発明の非燃焼吸引型たばこ製品によって達成され、この非燃焼吸引型たばこ製品はたばこ原料を裁刻又は粉砕して得られたたばこ粒状体と、粒状体からのニコチンの送出を安定させる少なくとも1種の安定剤とを含み、この安定剤は、ニコチンとの溶解性パラメータ間距離が１７以下で且つ２５℃での蒸気圧が１ｍｍＨｇ以下の特性を有する。 The above object is achieved by the non-combustion suction type tobacco product of the present invention. This non-combustion suction type tobacco product stabilizes the tobacco granules obtained by cutting or crushing tobacco raw materials and the delivery of nicotine from the granules. At least one stabilizer that has a solubility parameter distance with nicotine of 17 or less and a vapor pressure at 25 ° C. of 1 mmHg or less.
　上述の安定剤は、ニコチンの溶解性に優れ且つその蒸気圧が低いことから、ニコチンを安定して保持でき、ユーザへのニコチンの送出量を長期に亘って安定させる。
　例えば、安定剤はプロピレングリコール、ベンジルアルコール又はエステル基を有する化合物から選択され、ここでの化合物としては中鎖脂肪酸トリグリセリド、クエン酸トリエステル（クエン酸トリエチル、クエン酸トリブチル等）、ベンジルベンゾエート及びラウリン酸エチルから選択される。 Since the above-mentioned stabilizer is excellent in solubility of nicotine and its vapor pressure is low, nicotine can be stably held, and the amount of nicotine delivered to the user can be stabilized over a long period of time.
For example, the stabilizer is selected from propylene glycol, benzyl alcohol, or a compound having an ester group, which includes medium chain fatty acid triglycerides, citric acid triesters (triethyl citrate, tributyl citrate, etc.), benzyl benzoate and lauric acid. Selected from ethyl acid.
　安定剤はニコチン送出量の安定化をより図るうえで、溶解性パラメータ間距離が１２以下で且つ２５℃での蒸気圧が０．１ｍｍＨｇ以下の特性を有するのが好ましい。
　更に、たばこ粒状体は、スヌース等の嗅ぎたばこ製品で一般に用いられる炭酸塩及び炭酸水素塩のうちの少なくとも一方からなる添加剤を更に含むことができる。 In order to further stabilize the amount of nicotine delivered, the stabilizer preferably has a characteristic that the distance between solubility parameters is 12 or less and the vapor pressure at 25 ° C. is 0.1 mmHg or less.
Further, the tobacco particulates can further include an additive composed of at least one of a carbonate and a bicarbonate generally used in snuff products such as snus.
　一方、非燃焼吸引型たばこ製品は、たばこ粒状体を加熱するための加熱源を更に備えることもできる。この場合、安定剤は溶解性パラメータ間距離が１７以下で且つたばこ粒状体の加熱温度にて蒸気圧が１ｍｍＨｇ以下となる特性を有する。
　更に、安定剤の含有量は発生源の乾物重量に対し５重量％～２０重量％であるのが好ましい。この場合、安定剤の含有量が５重量％よりも少ないと、要求されるニコチンの安定化が得られず、逆に安定剤の含有量が２０重量％よりも多いと、安定剤が粒状体を凝集させてしまい、たばこ粒状体の取り扱い、つまり、その製造が困難になる。 On the other hand, the non-combustion suction type tobacco product may further include a heating source for heating the tobacco particulates. In this case, the stabilizer has a characteristic that the distance between the solubility parameters is 17 or less and the vapor pressure becomes 1 mmHg or less at the heating temperature of the tobacco granular material.
Further, the content of the stabilizer is preferably 5 to 20% by weight based on the dry matter weight of the source. In this case, if the content of the stabilizer is less than 5% by weight, the required stabilization of nicotine cannot be obtained. Conversely, if the content of the stabilizer is more than 20% by weight, the stabilizer becomes granular. The agglomerates are agglomerated, making it difficult to handle tobacco granules, that is, to produce them.
　本発明の非燃焼吸引型たばこ製品は、たばこ粒状体に安定剤が含まれているので、たばこ粒状体から放出されるたばこ特有の成分の１つであるニコチンの送出量を長期に亘って安定させることできる。 Since the non-combustion suction type tobacco product of the present invention contains a stabilizer in the tobacco granules, the amount of nicotine, which is one of the components unique to tobacco released from the tobacco granules, can be stabilized over a long period of time. Can be made.
一実施例の非燃焼吸引型たばこ製品の断面図である。It is sectional drawing of the non-combustion suction type tobacco product of one Example. 安定剤の効果を検証するための測定装置を示した概略図である。It is the schematic which showed the measuring apparatus for verifying the effect of a stabilizer. 安定剤の種類をパラメータとしてパフ回数とニコチン送出量との関係を示したグラフである。It is the graph which showed the relationship between the number of puffs and the amount of nicotine delivered with the type of stabilizer as a parameter. 他の安定剤の種類をパラメータとしてパフ回数とニコチン送出量との関係を示したグラフである。It is the graph which showed the relationship between the number of puffs and the amount of nicotine delivered, using the type of another stabilizer as a parameter. 安定剤の含有量をパラメータとしてパフ回数とニコチン送出量との関係を示したグラフである。It is the graph which showed the relationship between the number of puffs and the amount of nicotine delivered, using the stabilizer content as a parameter. 変形例の非燃焼吸引型たばこ製品の断面図である。It is sectional drawing of the non-combustion suction type tobacco product of a modification.
　図１に示す一実施例の非燃焼吸引型たばこ製品１は軸線Aと、この軸線Aに沿って並ぶ上流部材２、たばこカートリッジ６、下流部材１０及び吸い口部材１２を備えている。これら部材２，６，１０，１２は複数の連結ボルト・ナット１４により一体的に結合されている。
　例えば、上流部材２はステンレス鋼からなる厚み１ｍｍのシートであって、その中央域に開口領域１６を備えている。この開口領域１６は２３％の開口率を有する。具体的には、開口領域１６は一様に分布した直径１ｍｍの小孔によって形成されている。 The non-combustion suction type tobacco product 1 of one embodiment shown in FIG. 1 includes an axis A, an upstream member 2, a tobacco cartridge 6, a downstream member 10, and a mouthpiece member 12 aligned along the axis A. These members 2, 6, 10, 12 are integrally coupled by a plurality of connecting bolts / nuts 14.
For example, the upstream member 2 is a 1 mm thick sheet made of stainless steel, and includes an opening region 16 in the central region. The opening region 16 has an opening ratio of 23%. Specifically, the opening region 16 is formed by small holes having a diameter of 1 mm that are uniformly distributed.
　たばこカートリッジ６は、ステンレス鋼からなる厚み２ｍｍの枠部材１８を含み、この枠部材１８はその中央に内径２６ｍｍの開口部を有する。この開口部にはたばこ粒状体２０が収容され、このたばこ粒状体２０は通気性を有する。
　図１から明らかなように、たばこカートリッジ６は通気性の不織布４，８を更に含み、これら不織布４，８はたばこカートリッジ６の枠部材１８を挟み込み、枠部材１８からのたばこ粒状体２０の脱落を阻止する。
　なお、たばこ粒状体２０については後述する。 The cigarette cartridge 6 includes a frame member 18 made of stainless steel and having a thickness of 2 mm. The frame member 18 has an opening having an inner diameter of 26 mm at the center thereof. Tobacco granules 20 are accommodated in the openings, and the tobacco granules 20 have air permeability.
As is apparent from FIG. 1, the tobacco cartridge 6 further includes breathable nonwoven fabrics 4, 8 that sandwich the frame member 18 of the tobacco cartridge 6, and the tobacco particulates 20 fall off from the frame member 18. To prevent.
The tobacco granular material 20 will be described later.
　下流部材１０は上流部材２と同様にステンレス鋼からなる厚み１ｍｍのシートであって、その中央域に内径１８ｍｍの開口部２２を有する。
　一方、吸い口部材１２はテフロン（商標）から形成され、吸い口端２４を含む。この吸い口端２４は下流部材１０とは反対側の吸い口部材１２の面から突出し、６ｍｍの内径を有する。なお、下流部材１０側に位置した吸い口部材１２の開口部は２０ｍｍの内径を有する。 The downstream member 10 is a 1 mm thick sheet made of stainless steel like the upstream member 2, and has an opening 22 having an inner diameter of 18 mm in the central region.
On the other hand, the mouthpiece member 12 is formed of Teflon (trademark) and includes a mouth end 24. The mouth end 24 protrudes from the face of the mouth member 12 opposite to the downstream member 10 and has an inner diameter of 6 mm. The opening of the mouthpiece member 12 located on the downstream member 10 side has an inner diameter of 20 mm.
　上述したたばこ製品１によれば、ユーザが吸い口部材１２の吸い口端２４から吸引することで、外部の空気は上流部材２の開口領域１６から不織布４、たばこ粒状体２０、不織布８、下流部材１０の開口部２２及び吸い口部材１２を経てユーザの口腔内に流入する。ここでの、空気がたばこ粒状体２０を通過する際、たばこ粒状体２０から放出されたニコチンが空気に含まれることから、ユーザはニコチンを含んだ空気を吸い込むことになる。 According to the tobacco product 1 described above, when the user sucks from the mouth end 24 of the mouthpiece member 12, the external air flows from the opening region 16 of the upstream member 2 to the nonwoven fabric 4, the tobacco granular material 20, the nonwoven fabric 8, and the downstream. It flows into the user's mouth through the opening 22 of the member 10 and the mouthpiece member 12. Here, when the air passes through the tobacco granule 20, the nicotine released from the tobacco granule 20 is included in the air, and thus the user sucks in air containing nicotine.
　次に、たばこ粒状体２０について詳述する。
　たばこ粒状体２０は、国産のバーレー種の葉たばこからなるたばこ原料を裁刻又は粉砕し、この後、加湿及び加熱処理して得た粒状体と、例えば、炭酸塩及び炭酸水素塩の少なくとも一方からなる添加剤、具体的には炭酸カリウムとを含む混合物からなり、たばこ粒状体２０中、粒状体は乾物重量で３００ｍｇ含まれている。 Next, the tobacco granular material 20 will be described in detail.
The tobacco granule 20 is made from a granule obtained by chopping or pulverizing a tobacco raw material made of domestically produced Burley leaf tobacco, followed by humidification and heat treatment, and, for example, at least one of carbonate and bicarbonate. In the tobacco granular material 20, the granular material is contained in an amount of 300 mg by dry matter weight.
　この実施例の場合、混合物はたばこ原料の乾物重量に対して１２重量％の添加剤を含み、そして、粒状体に含まれるたばこ特有の成分の１つであるニコチンが乾物重量の２．３重量％、粒状体に含まれる揮発成分が粒状体の重量の１２重量％となるように調整されている。
　なお、ニコチンの含有量は、２００ｍｇ±２．５ｍｇの粒状体に１１重量％の水酸化ナトリウム水溶液７．５ｍｌ及びヘキサン１０ｍｌを加えたものにアルミホイルで遮光しながら室温にて６０分間振とうして抽出処理を行い、この後、ヘキサン相をガスクロマトグラフ質量分析計にて分析して得られた。 In this example, the mixture contains 12% by weight of additives based on the dry matter weight of the tobacco raw material, and nicotine, one of the tobacco-specific components contained in the granules, is 2.3% of the dry matter weight. %, And the volatile component contained in the granular material is adjusted to be 12% by weight of the weight of the granular material.
The content of nicotine was 200 mg ± 2.5 mg granule added with 7.5 ml of 11 wt% sodium hydroxide aqueous solution and 10 ml of hexane, and shaken at room temperature for 60 minutes while shielding light with aluminum foil. The hexane phase was obtained by analyzing with a gas chromatograph mass spectrometer.
　また、揮発成分の含有量は、２００ｍｇ±２ｍｇの粒状体を８０℃で３時間乾燥処理した後の粒状体の重量減少から求められる。
　更に、乾物重量とは粒状体の重量から上記の如く求められた揮発成分量を減じた値で表される。 Further, the content of the volatile component is determined from the weight reduction of the granular material after 200 mg ± 2 mg of the granular material is dried at 80 ° C. for 3 hours.
Further, the dry matter weight is represented by a value obtained by subtracting the amount of the volatile component obtained as described above from the weight of the granular material.
　更に、本実施例の場合、たばこ粒状体２０は上述の混合物に加えて、ユーザに対する前記ニコチンの送出量を安定させる少なくとも１種の安定剤を含み、この安定剤は、ニコチンとの溶解性パラメータ間距離が１７以下、好ましくは１２以下で且つ２５℃での蒸気圧が１ｍｍＨｇ以下、好ましくは０．１ｍｍＨｇ以下の特性を有する。 Furthermore, in the case of the present embodiment, the tobacco granule 20 includes, in addition to the above-mentioned mixture, at least one stabilizer that stabilizes the delivery amount of the nicotine to the user, and this stabilizer has a solubility parameter with nicotine. The distance is 17 or less, preferably 12 or less, and the vapor pressure at 25 ° C. is 1 mmHg or less, preferably 0.1 mmHg or less.
　詳しくは、溶解性パラメータ間距離とは溶媒に対する溶質の溶解性を示す指標であって、一般的にＲａ（ＭＰａ１／２）で表され、Ｒａは以下の式から求められる。
　Ｒａ＝［４＊（δｄ，２－δｄ，１）＾２＋（δｐ，２－δｐ，１）＾２
＋（δｈ，２－δｈ，１）＾２］＾（１／２）
　ここで、δｄ，δｐ，δｈは以下のように定義されている。
　δｄ＝溶解性パラメータの分散力
　δｐ＝溶解性パラメータの双極子相互作用
　δｈ＝溶解性パラメータの水素結合 Specifically, the distance between solubility parameters is an index indicating the solubility of a solute in a solvent, and is generally represented by Ra (MPa 1/2 ), and Ra is obtained from the following equation.
Ra = [4 * (δd, 2-δd, 1) ^ 2 + (δp, 2-δp, 1) ^ 2
+ (Δh, 2-δh, 1) ^ 2] ^ (1/2)
Here, δd, δp, and δh are defined as follows.
δd = Dispersion force of solubility parameter δp = Dipolar interaction of solubility parameter δh = Hydrogen bond of solubility parameter
　具体的には、安定剤はプロピレングリコール、ベンジルアルコール又はエステル基を有する化合物から選択され、ここでの化合物として中鎖脂肪酸トリグリセリド、クエン酸トリエステル（クエン酸トリエチル、クエン酸トリブチル等）、ベンジルベンゾエート及びラウリン酸エチルが挙げられる。 Specifically, the stabilizer is selected from propylene glycol, benzyl alcohol, or a compound having an ester group, and as the compound, medium chain fatty acid triglyceride, citric acid triester (triethyl citrate, tributyl citrate, etc.), benzylbenzoate And ethyl laurate.
　以下の表１に、グリセリン（Ａ）とともに、上述した安定剤の溶解性パラメータ間距離Ｒａ及び２５℃での蒸気圧をそれぞれ示す。
Table 1 below shows the solubility parameter distance Ra of the stabilizer and the vapor pressure at 25 ° C. together with glycerin (A).
Figure JPOXMLDOC01-appb-T000001
Figure JPOXMLDOC01-appb-T000001
　なお、安定剤Ｃはカプリル酸トリグリセリドを主成分とする中鎖脂肪酸トリグリセリド、具体的には花王株式会社製のココナードＭＴである。
　また、表１中の溶解性パラメータ間距離Ｒａは、Molecular Modeling Pro Version 6.01を使用した計算結果である。 The stabilizer C is a medium-chain fatty acid triglyceride mainly composed of caprylic acid triglyceride, specifically, Coconut MT manufactured by Kao Corporation.
The distance Ra between the solubility parameters in Table 1 is a calculation result using Molecular Modeling Pro Version 6.01.
　安定剤Ｂ～Ｈの効果を検証するため、図２に示す測定装置が使用され、この測定装置はユーザが上述のたばこ製品１を吸引したとき、このたばこ製品１からユーザに供給されるたばこ特有のニコチンの送出量を測定する。 In order to verify the effects of the stabilizers B to H, the measuring device shown in FIG. 2 is used. This measuring device is specific to the tobacco supplied from the tobacco product 1 to the user when the user sucks the tobacco product 1 described above. Measure the amount of nicotine delivered.
　詳しくは、測定装置は、エタノールを２０ｍｌ含むインピンジャ２６を備える。具体的には、インピンジャ２６には木下理化工業株式会社製の木下式ガス吸収洗浄瓶（標準型５０ｍｌ）が使用された。インピンジャ２６はその内部にフィルタ粒子（１００～２００μｍ）を有する一方、その内部から導出された吸引管２８及び送出管３０をそれぞれ有する。 Specifically, the measuring apparatus includes an impinger 26 containing 20 ml of ethanol. Specifically, a Kinoshita gas absorption cleaning bottle (standard type 50 ml) manufactured by Kinoshita Rika Kogyo Co., Ltd. was used for the impinger 26. The impinger 26 has filter particles (100 to 200 μm) inside thereof, and has a suction pipe 28 and a delivery pipe 30 respectively led out from the inside.
　吸引管２８には検証対象のたばこ製品１が接続可能になっており、一方、送出管３０には電磁弁３２、マスフローコントローラ(ＭＦＣ)３４を経て吸引ポンプ３６に接続されている。更に、電磁弁３２にはバルブコントローラ(ＶＣ)３８が電気的に接続され、このバルブコントローラ３８は電磁弁３２の開閉作動を制御する。 The tobacco product 1 to be verified can be connected to the suction pipe 28, while the delivery pipe 30 is connected to a suction pump 36 via an electromagnetic valve 32 and a mass flow controller (MFC) 34. Further, a valve controller (VC) 38 is electrically connected to the electromagnetic valve 32, and this valve controller 38 controls the opening / closing operation of the electromagnetic valve 32.
　具体的には、バルブコントローラ３８による開閉作動により、電磁弁３２は吸引ポンプ３６とインピンジャ２６との間を４秒間接続した後にインピンジャ２６を大気に１１秒間解放する１吸引サイクルを繰り返すことができる。なお、マスフローコントローラ３４の流量は３３００ｃｃ／ｍｉｎに設定されている。 More specifically, by the opening / closing operation by the valve controller 38, the solenoid valve 32 can repeat one suction cycle in which the impinger 26 is released to the atmosphere for 11 seconds after the suction pump 36 and the impinger 26 are connected for 4 seconds. The flow rate of the mass flow controller 34 is set to 3300 cc / min.
　検証対象のたばこ製品１として、たばこ粒状体２０にグリセリン（Ａ）や安定剤Ｂ～Ｈを何れも含まない第１比較例のたばこ製品、たばこ粒状体２０にグリセリン（Ａ）を含む比較例２のたばこ製品、そして、たばこ粒状体２０に安定剤Ｂ～Ｈをそれぞれ含む実施例のたばこ製品がそれぞれ準備された。 As a tobacco product 1 to be verified, a tobacco product of a first comparative example in which the tobacco granule 20 does not contain glycerin (A) or stabilizers B to H, and a comparative example 2 in which the tobacco granule 20 contains glycerin (A) Tobacco products and tobacco products of Examples each containing stabilizers B to H in tobacco granules 20 were prepared.
　ここで、比較例２及び各実施例のたばこ製品において、グリセリン（Ａ）及び安定剤Ｂ～Ｆの含有量はたばこ粒状体２０の乾物重量に対し、それぞれ１５重量％（４５ｍｇ）である。
　そして、インピンジャ２６の吸引管２８に比較例１，２及び実施例のたばこ製品の１つを接続した後、室温２２℃、湿度６０％の環境下にて、前述の吸引サイクルを５０回繰り返し、たばこ製品から送出されたニコチンをインピンジャ２６中のエタノール中に捕集した。 Here, in the tobacco products of Comparative Example 2 and each Example, the contents of glycerin (A) and stabilizers B to F are each 15% by weight (45 mg) with respect to the dry matter weight of the tobacco granules 20.
Then, after connecting one of the tobacco products of Comparative Examples 1 and 2 and the Example to the suction tube 28 of the impinger 26, the above suction cycle was repeated 50 times in an environment of room temperature 22 ° C. and humidity 60%, Nicotine delivered from the tobacco product was collected in ethanol in Impinger 26.
　この後、インピンジャ２６からニコチンを捕集したエタノールを取り出し、取り出したエタノールをガスクロマトグラフ質量分析計で分析し、そのたばこ製品からの１吸引サイクル（１パフ）当たりにおけるたばこ特有のニコチンを測定した。
　更に、総吸引サイクルが所定回数に達するまで、上述の捕集及び分析測定は繰り返して実施され、これにより、１つのたばこ製品に対する測定プロセスを完了させた。
　このような測定プロセスは各たばこ製品に対して実施され、その測定結果を図３及び図４に示す。 Thereafter, the ethanol from which the nicotine was collected was taken out from the impinger 26, the taken-out ethanol was analyzed with a gas chromatograph mass spectrometer, and tobacco-specific nicotine per one suction cycle (1 puff) from the tobacco product was measured.
In addition, the collection and analysis measurements described above were repeated until the total number of aspiration cycles reached a predetermined number of times, thereby completing the measurement process for one tobacco product.
Such a measurement process is carried out for each tobacco product, and the measurement results are shown in FIGS.
　ここで、安定剤Ｇ，Ｈを含む実施例のたばこ製品は、他の実施例と比較したとき、次の点で相違する。安定剤Ｇ，Ｈを含む実施例の場合、粒状体に含まれるニコチンはたばこ原料における乾燥重量の１．６重量％、粒状体に含まれる揮発成分は粒状体重量の１０重量％であった。 Here, the tobacco products of the examples containing the stabilizers G and H are different in the following points when compared with other examples. In the case of Examples containing stabilizers G and H, nicotine contained in the granules was 1.6% by weight of the dry weight of the tobacco raw material, and the volatile components contained in the granules were 10% by weight of the granules.
　図３及び図４から明らかなように安定剤Ｂ～Ｈを含む実施例のたばこ製品は、比較例１のたばこ製品（安定剤無し）に比べて、パフ回数の増加に伴うニコチンの送出量低下が抑制され、安定剤Ｂ～Ｈはニコチンの送出量を長期に亘って安定させるうえで有効であることが分かる。
　一方、比較例２のたばこ製品（グリセリンＡ）の場合、比較例１のたばこ製品（安定剤無し）に比べてパフ回数の増加に伴うニコチンの送出量低下はあまり変化がなく、グリセリンＡはニコチンの送出量の安定化を図るうえで有効でない。 As is apparent from FIGS. 3 and 4, the tobacco products of the examples containing stabilizers B to H are lower in the amount of nicotine delivered with the increase in the number of puffs than the tobacco products of comparative example 1 (without stabilizer). It can be seen that the stabilizers B to H are effective in stabilizing the delivery amount of nicotine over a long period of time.
On the other hand, in the case of the tobacco product of Comparative Example 2 (glycerin A), the decrease in the amount of nicotine delivered with the increase in the number of puffs was not significantly changed compared to the tobacco product of Comparative Example 1 (without stabilizer). It is not effective in stabilizing the delivery amount.
　これは、安定剤Ｂ～Ｈの何れもが１７以下の溶解パラメータ間距離Ｒａ及び２５℃にて１ｍｍＨｇ以下の蒸気圧となる特性を有しているのに対し、グリセリンＡはその溶解パラメータ間距離Ｒａが２３．０と大きいことに起因するものと考えられる。 This is because all of the stabilizers B to H have the characteristics such that the distance Ra between the solubility parameters is 17 or less and the vapor pressure is 1 mmHg or less at 25 ° C. This is probably because Ra is as large as 23.0.
　なお、安定剤Ｆを含むたばこ製品の場合、そのパフ回数に拘わらず、ニコチンの送出量が比較例１のたばこ製品に比べて低い。これは安定剤Ｆ（ベンジルアルコール）によるニコチンのトラップ効果が他の安定剤Ｂ～Ｅ，Ｇ，Ｈに比べて高いことに起因する。
　それ故、安定剤Ｆを使用する場合、安定剤Ｆの含有量を安定剤Ｂ～Ｅ，Ｇ，Ｈの含有量よりも少なくすれば、安定剤Ｆを含むたばこ製品は他の実施例のたばこ製品と同様にニコチンを送出することができるものと考えられる。なお、この点に関しては、後述する図５の測定結果の説明から明らかとなる。 In the case of the tobacco product containing the stabilizer F, the amount of nicotine delivered is lower than that of the tobacco product of Comparative Example 1 regardless of the number of puffs. This is because the trapping effect of nicotine by the stabilizer F (benzyl alcohol) is higher than that of the other stabilizers B to E, G and H.
Therefore, when the stabilizer F is used, if the content of the stabilizer F is made lower than the contents of the stabilizers B to E, G, H, the tobacco product containing the stabilizer F is the tobacco of other examples. It is thought that nicotine can be delivered in the same way as the product. This point will become clear from the description of the measurement results in FIG.
　一方、安定剤Ｆを含む実施例のたばこ製品の場合には図３から明らかなように、パフ回数の増加に連れ、ニコチンの送出量が増大する傾向を示す。このような傾向がユーザに違和感を与え、ユーザにとって望ましいものではないと考えられる場合、安定剤Ｆのように溶解パラメータ間距離Ｒａが１２以下の安定剤にあっては、その２５℃での蒸気圧が高すぎると考えられ、よって、２５℃での蒸気圧が０．１ｍｍＨｇ以下となる安定剤を選択するのが望ましい。 On the other hand, in the case of the tobacco product of the example containing the stabilizer F, as shown in FIG. 3, the nicotine delivery amount tends to increase as the number of puffs increases. When such a tendency gives the user a sense of incongruity and is not desirable for the user, in the case of a stabilizer having a solubility parameter distance Ra of 12 or less, such as the stabilizer F, the vapor at 25 ° C. The pressure is considered to be too high, and therefore it is desirable to select a stabilizer with a vapor pressure at 25 ° C. of 0.1 mmHg or less.
　一方、安定剤Ｄに着目し、この安定剤Ｄの含有量が前述の場合とは異なる実施例のたばこ製品を準備し、これらたばこ製品に対して前述の測定プロセスを同様に実施した後の測定結果を安定剤無しの測定結果とともに併せて示す。
　図４から明らかなように安定剤Ｄの含有量が５重量％（１５ｍｇ）、１０重量％（３０ｍｇ）、１５重量％（４５ｍｇ）と増加するに連れ、ニコチンの送出量は抑制され、且つ、その変化が長期に亘って少ないことが分かる。 On the other hand, paying attention to the stabilizer D, measurement is performed after preparing tobacco products of examples different from the above-mentioned cases in which the content of the stabilizer D is the same, and carrying out the same measurement process on these tobacco products in the same manner. The results are shown together with the measurement results without the stabilizer.
As is clear from FIG. 4, as the content of the stabilizer D increases to 5 wt% (15 mg), 10 wt% (30 mg), and 15 wt% (45 mg), the amount of nicotine delivered is suppressed, and It can be seen that the change is small over a long period of time.
　このことは、他の安定剤Ｂ，Ｃ，Ｅ，Ｆ～Ｈにも同様に当て嵌まるものと考えられることから、安定剤Ｂ～Ｈの含有量は５重量％～２０重量％であればよいことが分かる。ここで、その含有量が５重量％よりも少ないと、ニコチンの送出量に関し、所望の安定化効果が得られず、逆に、２０重量％よりも多いと、安定剤がたばこ粒状体２０を凝縮させ、たばこ粒状体２０の取り扱い、即ち、その製造を困難にする。 This is considered to apply to the other stabilizers B, C, E, and F to H in the same manner. Therefore, the content of the stabilizers B to H may be 5 wt% to 20 wt%. I understand that. Here, if the content is less than 5% by weight, a desired stabilizing effect cannot be obtained with respect to the delivery amount of nicotine. Conversely, if the content is more than 20% by weight, the stabilizer causes the tobacco granule 20 to be formed. Condensation makes handling of the tobacco granulate 20, ie its manufacture difficult.
　また、前述の安定剤Ｆを使用する場合、安定剤Ｆの含有量を他の安定剤の含有量に比べて少なくすれば、安定剤Ｆを含むたばこ製品は、安定剤Ｂ～Ｅ，Ｇ，Ｈを含むたばこ製品の同程度のニコチンの送出量を発生させることができると期待される。 Further, when the stabilizer F described above is used, if the content of the stabilizer F is reduced as compared with the content of other stabilizers, the tobacco products containing the stabilizer F can be used as stabilizers B to E, G, It is expected that a similar amount of nicotine delivered by tobacco products containing H can be generated.
　更に、非燃焼吸引型たばこ製品は、たばこ粒状体２０を加熱するための加熱源を含むことができる。例えば、図６に示されているように、たばこ製品の上流部材２は電気的なヒータ４０を内蔵する。このヒータ４０はたばこ製品の使用中、上流部材２、不織布４及び枠部材１８を介してたばこ粒状体２０を所望の温度に加熱する。
　この場合、たばこ粒状体２０に含まれる安定剤は、たばこ粒状体２０の加熱温度にて蒸気圧が１ｍｍＨｇ以下且つニコチンとの溶解性パラメータ間距離Ｒａが１７以下である。より好ましくは、安定剤は、たばこ粒状体２０の加熱温度にて蒸気圧が０．１ｍｍＨｇ以下且つ溶解性パラメータ間距離Ｒａが１２以下となる特性を有した安定剤の中から選択される。 Further, the non-combustion suction type tobacco product may include a heating source for heating the tobacco granules 20. For example, as shown in FIG. 6, the upstream member 2 of the tobacco product contains an electrical heater 40. The heater 40 heats the tobacco granular material 20 to a desired temperature via the upstream member 2, the nonwoven fabric 4 and the frame member 18 during use of the tobacco product.
In this case, the stabilizer contained in the tobacco granule 20 has a vapor pressure of 1 mmHg or less at the heating temperature of the tobacco granule 20 and a solubility parameter distance Ra with nicotine of 17 or less. More preferably, the stabilizer is selected from among stabilizers having such characteristics that the vapor pressure is 0.1 mmHg or less and the distance Ra between the solubility parameters is 12 or less at the heating temperature of the tobacco granule 20.
　以下の表２は、２５℃、７０℃及び１００℃でのグリセリン（Ａ）、上述の安定剤の蒸気圧をそれぞれ示す。 Table 2 below shows the vapor pressures of glycerin (A) and the above-mentioned stabilizer at 25 ° C., 70 ° C. and 100 ° C., respectively.
Figure JPOXMLDOC01-appb-T000002
 　表２中、７０℃及び１００℃での蒸気圧は、以下のクラジウス－クラペイロンの式により算出された。
　Ｐ＝Ｐ０＊ｅ＾（Ｌ／Ｒ）＊（１／Ｔ０－１／Ｔ）
　ここで、上式中の記号は以下のように定義されている。
　Ｐ：温度Ｔにおける蒸気圧[mmHg]
　Ｐ０：２５℃における蒸気圧[mmHg]
　Ｌ：蒸発熱[J/mol]
　Ｒ：気体定数[J/mol*K]
　Ｔ０：２９８[K]（２５℃）
　Ｔ：温度[K]
　表２から明らかなように、例えばたばこ粒状体２０の加熱温度が７０℃又は１００℃の場合、安定剤としてＣ，Ｄ，Ｅ，Ｇ，Ｈの選択が可能となる。
Figure JPOXMLDOC01-appb-T000002
 In Table 2, the vapor pressure at 70 ° C. and 100 ° C. was calculated by the following Clausius-Clapeyron equation.
P = P0 * e ^ (L / R) * (1 / T0-1 / T)
Here, the symbols in the above formula are defined as follows.
P: Vapor pressure at temperature T [mmHg]
P0: Vapor pressure at 25 ° C [mmHg]
L: Heat of evaporation [J / mol]
R: Gas constant [J / mol * K]
T0: 298 [K] (25 ° C)
T: Temperature [K]
As is clear from Table 2, for example, when the heating temperature of the tobacco granule 20 is 70 ° C. or 100 ° C., C, D, E, G, and H can be selected as the stabilizer.
　本発明は上述の一実施例に制約されるものではなく、種々の変形が可能である。例えば、溶解パラメータ間距離Ｒａが１７以下で且つ２５℃での蒸気圧が１ｍｍＨｇ以下の特性を有する安定剤であれば、前述した安定剤Ｂ～Ｈに限られるものでなく、また、これら安定剤Ｂ～Ｈを任意に組み合わせてもよく、更には、たばこ製品の構造自体もまた図１に示したものに限られるものでもない。 The present invention is not limited to the above-described embodiment, and various modifications can be made. For example, the stabilizer is not limited to the stabilizers B to H described above as long as the stabilizer has a characteristic in which the distance Ra between the dissolution parameters is 17 or less and the vapor pressure at 25 ° C. is 1 mmHg or less. B to H may be arbitrarily combined, and the structure of the tobacco product itself is not limited to that shown in FIG.
　また、たばこ粒状体２０の加熱温度にて、蒸気圧が１ｍｍＨｇ以下且つニコチンとの溶解性パラメータ間距離Ｒａが１７以下となる特性を有する安定剤が選択されれば、表２に例示した加熱温度に限らず、たばこ粒状体２０を任意の温度に加熱することができる。更に、たばこ粒状体２０の加熱方式もまた図６に例示した方式に限られるものではない。 Moreover, if the stabilizer which has the characteristic that vapor pressure is 1 mmHg or less and the distance Ra between solubility parameters with nicotine is 17 or less is selected at the heating temperature of the tobacco granule 20, the heating temperature illustrated in Table 2 is selected. Not limited to this, the tobacco granular material 20 can be heated to an arbitrary temperature. Furthermore, the heating method of the tobacco granular material 20 is not limited to the method illustrated in FIG.
１:たばこ製品、２:上流部材、４:不織布、６:たばこカートリッジ、８:不織布、１０:下流部材、１２:吸い口部材、１８:枠部材、２０:たばこ粒状体、２２:開口部、４０:ヒータ（加熱源） 1: tobacco product, 2: upstream member, 4: nonwoven fabric, 6: tobacco cartridge, 8: nonwoven fabric, 10: downstream member, 12: mouthpiece member, 18: frame member, 20: tobacco granular material, 22: opening, 40: Heater (heating source)

Claims (9)

  1. 　たばこ原料を裁刻又は粉砕して得られたたばこ粒状体を含み、このたばこ粒状体を燃焼させることなく前記たばこ粒状体から発生されたたばこ特有のニコチンを吸引空気に含ませ、この吸引空気とともにユーザの口腔内に送出する非燃焼吸引型たばこ製品であって、
    　前記たばこ粒状体はユーザへの前記ニコチンの送出を安定させる少なくとも1種の安定剤を更に含み、
    　前記安定剤は、前記ニコチンとの溶解性パラメータ間距離が１７以下で且つ２５℃での蒸気圧が１ｍｍＨｇ以下の特性を有することを特徴とする非燃焼吸引型たばこ製品。     Including tobacco particles obtained by cutting or pulverizing tobacco raw materials, and including tobacco-specific nicotine generated from the tobacco particles without burning the tobacco particles, together with the suction air A non-combustion suction type tobacco product to be delivered into the user's mouth,
    The tobacco granule further comprises at least one stabilizer that stabilizes delivery of the nicotine to a user;
    The non-combustion suction-type tobacco product, wherein the stabilizer has a characteristic that a distance between solubility parameters with the nicotine is 17 or less and a vapor pressure at 25 ° C is 1 mmHg or less.
  2. 　前記安定剤は、プロピレングリコール、ベンジルアルコール又はエステル基を有する化合物から選択されていることを特徴とする請求項１に記載の非燃焼吸引型たばこ製品。 The non-burning suction type tobacco product according to claim 1, wherein the stabilizer is selected from propylene glycol, benzyl alcohol or a compound having an ester group.
  3. 　前記安定剤は、前記溶解性パラメータ間距離が１２以下で且つ２５℃での蒸気圧が０．１ｍｍＨｇ以下の特性を有することを特徴とする請求項１又は２に記載の非燃焼吸引型たばこ製品。 The non-combustion suction type tobacco product according to claim 1 or 2, wherein the stabilizer has a characteristic in which a distance between the solubility parameters is 12 or less and a vapor pressure at 25 ° C is 0.1 mmHg or less. .
  4. 　前記安定剤は前記エステル基を有する化合物であることを特徴とする請求項３に記載の非燃焼吸引型たばこ製品。 The non-combustion suction type tobacco product according to claim 3, wherein the stabilizer is a compound having the ester group.
  5. 　前記化合物は、中鎖脂肪酸トリグリセリド、クエン酸トリエステル、ベンジルベンゾエート及びラウリン酸エチルから選択されていることを特徴とする請求項４に記載の非燃焼吸引型たばこ製品。 The non-combustion suction type tobacco product according to claim 4, wherein the compound is selected from medium chain fatty acid triglycerides, citric acid triester, benzyl benzoate and ethyl laurate.
  6. 　前記クエン酸トリエステルは、クエン酸トリエチル又はクエン酸トリブチルであることを特徴とする請求項５に記載の非燃焼吸引型たばこ製品。 The non-burning suction type tobacco product according to claim 5, wherein the citric acid triester is triethyl citrate or tributyl citrate.
  7. 　前記たばこ粒状体は、炭酸塩及び炭酸水素塩のうちの少なくとも一方からなる添加剤を更に含むことを特徴とする請求項５に記載の非燃焼吸引型たばこ製品。 The non-combustion suction-type tobacco product according to claim 5, wherein the tobacco granular material further includes an additive composed of at least one of carbonate and bicarbonate.
  8. 　前記たばこ粒状体を所定の温度に加熱する加熱源を更に備え、
    　前記安定剤は前記溶解性パラメータ間距離が１７以下で且つ前記たばこ粒状体の加熱温度にて蒸気圧が１ｍｍＨｇ以下となる特性を有することを特徴とする請求項５に記載の非燃焼吸引型たばこ製品。     A heating source for heating the tobacco particulates to a predetermined temperature;
    6. The non-combustion suction type tobacco according to claim 5, wherein the stabilizer has a characteristic that a distance between the solubility parameters is 17 or less and a vapor pressure is 1 mmHg or less at a heating temperature of the tobacco granular material. Product.
  9. 　前記安定剤の含有量は前記たばこ粒状体の乾物重量に対し５重量％～２０重量％であることを特徴とする請求項１に記載の非燃焼吸引型たばこ製品。
          The non-combustion suction type tobacco product according to claim 1, wherein a content of the stabilizer is 5% by weight to 20% by weight with respect to a dry matter weight of the tobacco granular material.
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