EP1284741B1
(en)
|
2000-04-13 |
2008-11-19 |
Pharmasset, Inc. |
3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of viral infections
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
WO2001092282A2
(en)
|
2000-05-26 |
2001-12-06 |
Idenix (Cayman) Limited |
Methods and compositions for treating flaviviruses and pestiviruses
|
EP2360166A1
(en)
|
2001-01-22 |
2011-08-24 |
Merck Sharp & Dohme Corp. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
US7105499B2
(en)
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
US8481712B2
(en)
|
2001-01-22 |
2013-07-09 |
Merck Sharp & Dohme Corp. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
GB0114286D0
(en)
*
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
CN101172993A
(zh)
*
|
2002-06-28 |
2008-05-07 |
埃迪尼克斯(开曼)有限公司 |
用于治疗黄病毒感染的2′-c-甲基-3′-o-l-缬氨酸酯核糖呋喃基胞苷
|
US7608600B2
(en)
*
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
CA2489552A1
(en)
*
|
2002-06-28 |
2004-01-08 |
Idenix (Cayman) Limited |
2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
|
AU2003257157C1
(en)
|
2002-08-01 |
2010-03-18 |
Pharmasset Inc. |
Compounds with the bicyclo[4.2.1] nonane system for the treatment of Flaviviridae infections
|
BR0315795A
(pt)
|
2002-10-31 |
2005-09-13 |
Metabasis Therapeutics Inc |
Pró-medicamentos de monofosfato de citarabina
|
AU2003298658A1
(en)
*
|
2002-11-15 |
2004-06-15 |
Idenix (Cayman) Limited |
2'-branched nucleosides and flaviviridae mutation
|
KR20050109918A
(ko)
*
|
2002-12-12 |
2005-11-22 |
이데닉스 (케이만) 리미티드 |
2'-분지형 뉴클레오시드의 제조 방법
|
WO2005011709A1
(en)
*
|
2003-02-19 |
2005-02-10 |
Yale University |
Anti-viral nucleoside analogs and methods for treating viral infections, especially hiv infections
|
CN101415719A
(zh)
*
|
2003-03-20 |
2009-04-22 |
微生物化学及药品有限公司 |
生产2’-脱氧-β-L-核苷的方法
|
CN1980678A
(zh)
*
|
2003-03-28 |
2007-06-13 |
法莫赛特股份有限公司 |
治疗黄病毒感染的化合物
|
CN1852915A
(zh)
*
|
2003-07-25 |
2006-10-25 |
艾登尼科斯(开曼)有限公司 |
治疗包括丙型肝炎的黄病毒科病毒所致疾病的嘌呤核苷类似物
|
WO2005018330A1
(en)
*
|
2003-08-18 |
2005-03-03 |
Pharmasset, Inc. |
Dosing regimen for flaviviridae therapy
|
JP2007515495A
(ja)
*
|
2003-12-22 |
2007-06-14 |
ギリアード サイエンシーズ, インコーポレイテッド |
4’−置換カルボビル誘導体およびアバカビル誘導体ならびにhivおよびhcv抗ウイルス活性を有する関連化合物
|
US20050182252A1
(en)
|
2004-02-13 |
2005-08-18 |
Reddy K. R. |
Novel 2'-C-methyl nucleoside derivatives
|
EA013207B1
(ru)
|
2004-02-20 |
2010-04-30 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Ингибиторы вирусной полимеразы
|
EP1758453B1
(en)
|
2004-06-15 |
2014-07-16 |
Merck Sharp & Dohme Corp. |
C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase
|
WO2006000922A2
(en)
*
|
2004-06-23 |
2006-01-05 |
Idenix (Cayman) Limited |
5-aza-7-deazapurine derivatives for treating infections with flaviviridae
|
EP1773355B1
(en)
|
2004-06-24 |
2014-06-25 |
Merck Sharp & Dohme Corp. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
ES2327252T3
(es)
|
2004-08-23 |
2009-10-27 |
F. Hoffmann-La Roche Ag |
4'-azido nucleosidos antivirales.
|
US7524831B2
(en)
|
2005-03-02 |
2009-04-28 |
Schering Corporation |
Treatments for Flaviviridae virus infection
|
CA2606195C
(en)
|
2005-05-02 |
2015-03-31 |
Merck And Co., Inc. |
Hcv ns3 protease inhibitors
|
AR057456A1
(es)
|
2005-07-20 |
2007-12-05 |
Merck & Co Inc |
Inhibidores de la proteasa ns3 del vhc
|
CA2615896C
(en)
|
2005-08-01 |
2012-11-13 |
Merck & Co., Inc. |
Macrocyclic peptides as hcv ns3 protease inhibitors
|
WO2007075876A2
(en)
*
|
2005-12-23 |
2007-07-05 |
Idenix Pharmaceuticals, Inc. |
Process for preparing a synthetic intermediate for preparation of branched nucleosides
|
GB0609492D0
(en)
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
GB0612423D0
(en)
|
2006-06-23 |
2006-08-02 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
NZ575889A
(en)
|
2006-10-10 |
2011-09-30 |
Medivir Ab |
Hcv nucleoside inhibitor
|
WO2008051477A2
(en)
|
2006-10-24 |
2008-05-02 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
US8138164B2
(en)
|
2006-10-24 |
2012-03-20 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
AU2007309488B2
(en)
|
2006-10-24 |
2012-10-11 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
MY164469A
(en)
|
2006-10-27 |
2017-12-15 |
Msd Italia Srl |
Hcv ns3 protease inhibitors
|
WO2008057208A2
(en)
|
2006-10-27 |
2008-05-15 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
GB0625345D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
US8101595B2
(en)
|
2006-12-20 |
2012-01-24 |
Istituto di Ricerche di Biologia Molecolare P. Angletti SpA |
Antiviral indoles
|
GB0625349D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
US7951789B2
(en)
|
2006-12-28 |
2011-05-31 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
US8071568B2
(en)
|
2007-01-05 |
2011-12-06 |
Merck Sharp & Dohme Corp. |
Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
CA2693537C
(en)
|
2007-07-17 |
2013-06-25 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa |
Macrocyclic indole derivatives for the treatment of hepatitis c infections
|
JP5433573B2
(ja)
|
2007-07-19 |
2014-03-05 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・エルレ・エルレ |
抗ウイルス剤としての大環状化合物
|
WO2009125841A1
(ja)
*
|
2008-04-10 |
2009-10-15 |
浜理薬品工業株式会社 |
5-メチルウリジンを出発原料とするエチニルチミジン化合物の製造方法
|
HUE025528T2
(en)
*
|
2008-04-23 |
2016-05-30 |
Gilead Sciences Inc |
1'-substituted carba-nucleoside analogs for antiviral treatment
|
CA2720850A1
(en)
|
2008-04-28 |
2009-11-05 |
Merck Sharp & Dohme Corp. |
Hcv ns3 protease inhibitors
|
CA2731177C
(en)
|
2008-07-22 |
2013-10-29 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Macrocyclic quinoxaline compounds as hcv ns3 protease inhibitors
|
WO2010082050A1
(en)
|
2009-01-16 |
2010-07-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections
|
GB0900914D0
(en)
|
2009-01-20 |
2009-03-04 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
PT2396340E
(pt)
*
|
2009-02-10 |
2014-03-26 |
Gilead Sciences Inc |
Análogos de carba-nucleosídeo para tratamento antiviral
|
US8828930B2
(en)
|
2009-07-30 |
2014-09-09 |
Merck Sharp & Dohme Corp. |
Hepatitis C virus NS3 protease inhibitors
|
EP2459211A1
(en)
|
2009-07-31 |
2012-06-06 |
Medtronic, Inc. |
Continuous subcutaneous administration of interferon- to hepatitis c infected patients
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
EP2480559B1
(en)
|
2009-09-21 |
2013-07-03 |
Gilead Sciences, Inc. |
Processes and intermediates for the preparation of 1'-cyano-carbanucleoside analogs
|
NZ599402A
(en)
|
2009-09-21 |
2014-02-28 |
Gilead Sciences Inc |
2’ -fluoro substituted carba-nucleoside analogs for antiviral treatment
|
CA2780044A1
(en)
|
2009-11-14 |
2011-05-19 |
F. Hoffmann-La Roche Ag |
Biomarkers for predicting rapid response to hcv treatment
|
EP2507636A1
(en)
|
2009-12-02 |
2012-10-10 |
F. Hoffmann-La Roche AG |
Biomarkers for predicting sustained response to hcv treatment
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
KR20200052384A
(ko)
|
2010-07-19 |
2020-05-14 |
길리애드 사이언시즈, 인코포레이티드 |
부분입체 이성질성으로 순수한 포스포라미데이트 전구약물의 제조 방법
|
EP2595980B1
(en)
|
2010-07-22 |
2014-09-03 |
Gilead Sciences, Inc. |
Methods and compounds for treating paramyxoviridae virus infections
|
EP2619206A1
(en)
|
2010-09-20 |
2013-07-31 |
Gilead Sciences, Inc. |
2' -fluoro substituted carba-nucleoside analogs for antiviral treatment
|
US8877731B2
(en)
|
2010-09-22 |
2014-11-04 |
Alios Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
EP2691409B1
(en)
|
2011-03-31 |
2018-02-21 |
Idenix Pharmaceuticals LLC. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
JP2014511875A
(ja)
|
2011-04-13 |
2014-05-19 |
メルク・シャープ・アンド・ドーム・コーポレーション |
2’−シアノ置換ヌクレオシド誘導体およびウイルス疾患の治療のためのその使用方法
|
US9156872B2
(en)
|
2011-04-13 |
2015-10-13 |
Merck Sharp & Dohme Corp. |
2′-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
EP2696681B1
(en)
|
2011-04-13 |
2018-10-03 |
Merck Sharp & Dohme Corp. |
2'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
US8877733B2
(en)
|
2011-04-13 |
2014-11-04 |
Gilead Sciences, Inc. |
1′-substituted pyrimidine N-nucleoside analogs for antiviral treatment
|
US9416154B2
(en)
|
2011-07-13 |
2016-08-16 |
Merck Sharp & Dohme Corp. |
5′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
US9408863B2
(en)
|
2011-07-13 |
2016-08-09 |
Merck Sharp & Dohme Corp. |
5′-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases
|
TW201329096A
(zh)
|
2011-09-12 |
2013-07-16 |
Idenix Pharmaceuticals Inc |
經取代羰氧基甲基磷酸醯胺化合物及用於治療病毒感染之藥學組成物
|
WO2013074386A2
(en)
|
2011-11-15 |
2013-05-23 |
Merck Sharp & Dohme Corp. |
Hcv ns3 protease inhibitors
|
LT2794627T
(lt)
|
2011-12-22 |
2019-01-10 |
Alios Biopharma, Inc. |
Pakeistieji nukleozidai, nukleotidai ir jų analogai
|
WO2013133399A1
(ja)
*
|
2012-03-09 |
2013-09-12 |
大鵬薬品工業株式会社 |
Dna障害剤
|
USRE48171E1
(en)
|
2012-03-21 |
2020-08-25 |
Janssen Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
US9441007B2
(en)
|
2012-03-21 |
2016-09-13 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
WO2013177195A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharmaceuticals, Inc. |
3',5'-cyclic phosphate prodrugs for hcv infection
|
WO2013177188A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharmaceuticals, Inc. |
3',5'-cyclic phosphoramidate prodrugs for hcv infection
|
EA031301B1
(ru)
|
2012-05-22 |
2018-12-28 |
Иденикс Фармасьютикалз Ллс |
D-аминокислотные химические соединения для лечения заболеваний печени
|
UY34824A
(es)
|
2012-05-25 |
2013-11-29 |
Janssen R & D Ireland |
Nucleósidos de espirooxetano de uracilo
|
US9192621B2
(en)
|
2012-09-27 |
2015-11-24 |
Idenix Pharmaceuticals Llc |
Esters and malonates of SATE prodrugs
|
US10513534B2
(en)
|
2012-10-08 |
2019-12-24 |
Idenix Pharmaceuticals Llc |
2′-chloro nucleoside analogs for HCV infection
|
WO2014069520A1
(ja)
|
2012-10-31 |
2014-05-08 |
武田薬品工業株式会社 |
新規修飾核酸
|
WO2014099941A1
(en)
|
2012-12-19 |
2014-06-26 |
Idenix Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
SI2935303T1
(sl)
|
2012-12-21 |
2021-08-31 |
Janssen Biopharma, Inc. |
4'-fluoro-nukleozidi, 4'-fluoro-nukleotidi in njihovi analogi za zdravljenje HCV
|
WO2014121417A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
WO2014121418A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
US9309275B2
(en)
|
2013-03-04 |
2016-04-12 |
Idenix Pharmaceuticals Llc |
3′-deoxy nucleosides for the treatment of HCV
|
WO2014160484A1
(en)
|
2013-03-13 |
2014-10-02 |
Idenix Pharmaceuticals, Inc. |
Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
|
RU2534613C2
(ru)
|
2013-03-22 |
2014-11-27 |
Александр Васильевич Иващенко |
Алкил 2-{ [(2r,3s,5r)-5-(4-амино-2-оксо-2н-пиримидин-1-ил)- -гидрокси-тетрагидро-фуран-2-илметокси]-фенокси-фосфориламино} -пропионаты, нуклеозидные ингибиторы рнк-полимеразы hcv ns5b, способы их получения и применения
|
WO2014165542A1
(en)
|
2013-04-01 |
2014-10-09 |
Idenix Pharmaceuticals, Inc. |
2',4'-fluoro nucleosides for the treatment of hcv
|
US10005779B2
(en)
|
2013-06-05 |
2018-06-26 |
Idenix Pharmaceuticals Llc |
1′,4′-thio nucleosides for the treatment of HCV
|
EP3027636B1
(en)
|
2013-08-01 |
2022-01-05 |
Idenix Pharmaceuticals LLC |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
JP6762873B2
(ja)
*
|
2013-09-11 |
2020-09-30 |
エモリー・ユニバーシテイ |
ヌクレオチドおよびヌクレオシド組成物ならびにこれらに関連する使用
|
JP6562908B2
(ja)
*
|
2013-10-11 |
2019-08-21 |
ヤンセン バイオファーマ インク. |
置換ヌクレオシド、置換ヌクレオチドおよびその類似体
|
US10449210B2
(en)
|
2014-02-13 |
2019-10-22 |
Ligand Pharmaceuticals Inc. |
Prodrug compounds and their uses
|
EP3131914B1
(en)
|
2014-04-16 |
2023-05-10 |
Idenix Pharmaceuticals LLC |
3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
|
WO2016003812A1
(en)
|
2014-07-02 |
2016-01-07 |
Ligand Pharmaceuticals, Inc. |
Prodrug compounds and uses therof
|
MA40149A1
(fr)
|
2014-09-26 |
2019-04-30 |
Riboscience Llc |
Dérivés de nucléoside 4'-vinyle substitués utiles en tant qu'inhibiteurs de la réplication due l'arn du virus respiratoire syncytial
|
TWI767201B
(zh)
|
2014-10-29 |
2022-06-11 |
美商基利科學股份有限公司 |
絲狀病毒科病毒感染之治療
|
KR102630013B1
(ko)
|
2015-08-06 |
2024-01-25 |
키메릭스 인크. |
항바이러스제로서 유용한 피롤로피리미딘 뉴클레오시드 및 그의 유사체
|
PT3349758T
(pt)
|
2015-09-16 |
2022-07-13 |
Gilead Sciences Inc |
Métodos para o tratamento de infeções pelo vírus arenaviridae
|
TW201836615A
(zh)
|
2017-03-14 |
2018-10-16 |
美商基利科學股份有限公司 |
治療貓冠狀病毒感染之方法
|
CN115403626A
(zh)
|
2017-05-01 |
2022-11-29 |
吉利德科学公司 |
新结晶形式
|
TW201919648A
(zh)
|
2017-07-11 |
2019-06-01 |
美商基利科學股份有限公司 |
用於治療病毒感染之含rna聚合酶抑制劑與環糊精的組合物
|
EP3684771A1
(en)
|
2017-09-21 |
2020-07-29 |
Chimerix, Inc. |
MORPHIC FORMS OF 4-AMINO-7-(3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-2-METHYL-7H-PYRROLO[2,3-d]PYRIMIDINE-5-CARBOXAMIDE AND USES THEREOF
|
EP3737676B1
(en)
|
2018-01-09 |
2024-03-06 |
Ligand Pharmaceuticals, Inc. |
Acetal compounds and therapeutic uses thereof
|
CN108484705B
(zh)
*
|
2018-01-25 |
2020-09-01 |
中国医学科学院医药生物技术研究所 |
一种西奈芬净类似物及其制备方法
|
JP2023512656A
(ja)
|
2020-01-27 |
2023-03-28 |
ギリアード サイエンシーズ, インコーポレイテッド |
SARS CoV-2感染を治療するための方法
|
TW202309061A
(zh)
|
2020-03-12 |
2023-03-01 |
美商基利科學股份有限公司 |
1’-氰基核苷之製備方法
|
AU2021251689B2
(en)
|
2020-04-06 |
2024-06-13 |
Gilead Sciences, Inc. |
Inhalation formulations of 1'-cyano substituted carbanucleoside analogs
|
TW202203941A
(zh)
|
2020-05-29 |
2022-02-01 |
美商基利科學股份有限公司 |
瑞德西韋之治療方法
|
EP4172160A2
(en)
|
2020-06-24 |
2023-05-03 |
Gilead Sciences, Inc. |
1'-cyano nucleoside analogs and uses thereof
|
WO2022047065A2
(en)
|
2020-08-27 |
2022-03-03 |
Gilead Sciences, Inc. |
Compounds and methods for treatment of viral infections
|
CN112979733B
(zh)
*
|
2021-04-25 |
2021-09-10 |
南京颐媛生物医学研究院有限公司 |
抗乙肝病毒的化合物及其制备方法和应用
|
TW202400185A
(zh)
|
2022-03-02 |
2024-01-01 |
美商基利科學股份有限公司 |
用於治療病毒感染的化合物及方法
|