UY26544A1 - Antagonistas del factor liberador de corticotropina. - Google Patents

Antagonistas del factor liberador de corticotropina.

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Publication number
UY26544A1
UY26544A1 UY26544A UY26544A UY26544A1 UY 26544 A1 UY26544 A1 UY 26544A1 UY 26544 A UY26544 A UY 26544A UY 26544 A UY26544 A UY 26544A UY 26544 A1 UY26544 A1 UY 26544A1
Authority
UY
Uruguay
Prior art keywords
releasing factor
corticotropin releasing
factor antagonists
disorders
antagonists
Prior art date
Application number
UY26544A
Other languages
English (en)
Inventor
Yuhpyng Liang Chen
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of UY26544A1 publication Critical patent/UY26544A1/es

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C07D213/643—2-Phenoxypyridines; Derivatives thereof
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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Abstract

Antagonistas del factor liberador de corticotropina (CRF) que tienen las fórmulas donde las líneas de puntos, A,B,Y,Z,G,R3,R4,R5,R6,R16 y R17 son como se han definido en la solicitud, y procedimientos para prepararlos. Estos compuestos y sus sales farmacéuticamente aceptables son útiles en el tratamiento de trastornos que incluyen trastornos del sistema nervioso central (CNS) y trastornos relacionados con el estrés.
UY26544A 2000-01-18 2001-01-18 Antagonistas del factor liberador de corticotropina. UY26544A1 (es)

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AP (1) AP2002002583A0 (es)
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BR (1) BR0107662A (es)
CA (1) CA2397633A1 (es)
CO (1) CO5271658A1 (es)
CR (1) CR6698A (es)
CZ (1) CZ20022390A3 (es)
EA (2) EA200200688A1 (es)
EE (1) EE200200400A (es)
GT (1) GT200100007A (es)
HN (1) HN2001000006A (es)
HR (1) HRP20020599A2 (es)
HU (1) HUP0204272A3 (es)
IL (1) IL150632A0 (es)
IS (1) IS6445A (es)
MA (1) MA26864A1 (es)
MX (1) MXPA02007047A (es)
NO (1) NO20023424L (es)
OA (1) OA12157A (es)
PA (1) PA8510001A1 (es)
PE (1) PE20011166A1 (es)
PL (1) PL357589A1 (es)
SK (1) SK10062002A3 (es)
SV (1) SV2002000289A (es)
TN (1) TNSN01008A1 (es)
UY (1) UY26544A1 (es)
WO (1) WO2001053263A1 (es)
YU (1) YU54402A (es)
ZA (1) ZA200205660B (es)

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HN2001000006A (es) 2001-06-13
HUP0204272A2 (hu) 2003-03-28
SV2002000289A (es) 2002-07-16
PL357589A1 (en) 2004-07-26
AU779995B2 (en) 2005-02-24
HRP20020599A2 (en) 2004-08-31
PE20011166A1 (es) 2001-11-13
YU54402A (sh) 2005-11-28
MXPA02007047A (es) 2002-12-13
TNSN01008A1 (fr) 2005-11-10
BR0107662A (pt) 2002-11-19
CA2397633A1 (en) 2001-07-26
WO2001053263A1 (en) 2001-07-26
IS6445A (is) 2002-06-25
HUP0204272A3 (en) 2005-03-29
CN1395566A (zh) 2003-02-05
EE200200400A (et) 2003-10-15
SK10062002A3 (sk) 2004-05-04
US6833378B2 (en) 2004-12-21
MA26864A1 (fr) 2004-12-20
AU2390501A (en) 2001-07-31
CR6698A (es) 2004-01-14
NO20023424D0 (no) 2002-07-17
IL150632A0 (en) 2003-02-12
AR027221A1 (es) 2003-03-19
EA200300834A1 (ru) 2004-02-26
OA12157A (en) 2006-05-08
AP2002002583A0 (en) 2002-09-30
CZ20022390A3 (cs) 2003-08-13
US20020016328A1 (en) 2002-02-07
PA8510001A1 (es) 2002-12-11
BG106853A (bg) 2003-01-31
GT200100007A (es) 2001-10-19
NO20023424L (no) 2002-09-10
EP1263732A1 (en) 2002-12-11
KR20020063934A (ko) 2002-08-07
JP2003520272A (ja) 2003-07-02
ZA200205660B (en) 2003-10-09
CO5271658A1 (es) 2003-04-30
EA200200688A1 (ru) 2003-02-27

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