UY26498A1 - Pirroles sustituidos - Google Patents

Pirroles sustituidos

Info

Publication number
UY26498A1
UY26498A1 UY26498A UY26498A UY26498A1 UY 26498 A1 UY26498 A1 UY 26498A1 UY 26498 A UY26498 A UY 26498A UY 26498 A UY26498 A UY 26498A UY 26498 A1 UY26498 A1 UY 26498A1
Authority
UY
Uruguay
Prior art keywords
substituted pyrroles
compounds
useful
formula
pharmaceutically acceptable
Prior art date
Application number
UY26498A
Other languages
English (en)
Inventor
Allen John Lovey
Nader Fatouhi
Norman Kong
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of UY26498A1 publication Critical patent/UY26498A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Abstract

Se describen pirroles sustituidos que tienen la fórmula I . Estos compuestos y sus sales farmacéuticamente aceptables son útiles en el tratamiento y/o control de trastornos de proliferación celular, en particular cáncer. Asimismo se describen composiciones farmacéuticas que contienen los compuestos precedentes.
UY26498A 1999-12-22 2000-12-21 Pirroles sustituidos UY26498A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17155799P 1999-12-22 1999-12-22

Publications (1)

Publication Number Publication Date
UY26498A1 true UY26498A1 (es) 2001-06-29

Family

ID=22624198

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26498A UY26498A1 (es) 1999-12-22 2000-12-21 Pirroles sustituidos

Country Status (28)

Country Link
US (1) US6281356B1 (es)
EP (1) EP1242409A2 (es)
JP (1) JP2003518112A (es)
KR (1) KR100508741B1 (es)
CN (1) CN1193027C (es)
AR (1) AR027035A1 (es)
AU (1) AU782920B2 (es)
BR (1) BR0016516A (es)
CA (1) CA2394852A1 (es)
CO (1) CO5090902A1 (es)
CZ (1) CZ20022492A3 (es)
HK (1) HK1054382A1 (es)
HR (1) HRP20020536A2 (es)
HU (1) HUP0204572A3 (es)
IL (1) IL150200A0 (es)
JO (1) JO2199B1 (es)
MA (1) MA26860A1 (es)
MX (1) MXPA02006162A (es)
MY (1) MY133682A (es)
NO (1) NO20022927D0 (es)
NZ (1) NZ519359A (es)
PE (1) PE20011098A1 (es)
PL (1) PL357603A1 (es)
RU (1) RU2261862C2 (es)
UY (1) UY26498A1 (es)
WO (1) WO2001046178A2 (es)
YU (1) YU46302A (es)
ZA (1) ZA200204313B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030139373A1 (en) * 2001-11-20 2003-07-24 Breimer Lars Holger Method for cancer therapy
TWI324064B (en) 2002-04-03 2010-05-01 Novartis Ag Indolylmaleimide derivatives
GB0303319D0 (en) 2003-02-13 2003-03-19 Novartis Ag Organic compounds
KR102244719B1 (ko) 2013-03-15 2021-04-26 플렉시콘 인코퍼레이티드 헤테로시클릭 화합물 및 그의 용도
US20140303121A1 (en) 2013-03-15 2014-10-09 Plexxikon Inc. Heterocyclic compounds and uses thereof
PT3272745T (pt) * 2016-07-21 2019-09-27 Inst Farmakologii Polskiej Akademii Nauk Derivados de indol substituídos com imidazolilo que se ligam ao recetor de serotonina 5-ht7 e composições farmacêuticas dos mesmos
WO2019075243A1 (en) 2017-10-13 2019-04-18 Plexxikon Inc. SOLID FORMS OF A COMPOUND FOR MODULATING KINASES

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ227850A (en) 1988-02-10 1991-11-26 Hoffmann La Roche Indole substituted pyrrole derivatives; preparatory process and medicaments for use against inflammatory immunological, bronchopulmonary or vascular disorders
IL94274A0 (en) * 1989-05-05 1991-03-10 Goedecke Ag Maleinimide derivatives,process for the preparation thereof and pharmaceutical compositions containing the same
US5380746A (en) 1989-05-05 1995-01-10 Goedecke Aktiengesellschaft Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
EP0630241A1 (en) 1992-03-20 1994-12-28 The Wellcome Foundation Limited Indole derivatives with antiviral activity
WO1993018766A1 (en) * 1992-03-20 1993-09-30 The Wellcome Foundation Limited Further indole derivatives with antiviral activity
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
PE91598A1 (es) 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
PE91498A1 (es) 1996-07-29 1998-12-22 Hoffmann La Roche Pirroles sustituidos
PE91698A1 (es) 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
ATE243693T1 (de) * 1998-03-17 2003-07-15 Hoffmann La Roche Substituierte bisindolylmaleimide zur inhibierung der zellproliferation

Also Published As

Publication number Publication date
IL150200A0 (en) 2002-12-01
HK1054382A1 (en) 2003-11-28
MA26860A1 (fr) 2004-12-20
EP1242409A2 (en) 2002-09-25
NO20022927L (no) 2002-06-18
US6281356B1 (en) 2001-08-28
MY133682A (en) 2007-11-30
ZA200204313B (en) 2003-08-29
CN1411457A (zh) 2003-04-16
PL357603A1 (en) 2004-07-26
CZ20022492A3 (cs) 2003-02-12
JP2003518112A (ja) 2003-06-03
CO5090902A1 (es) 2001-10-30
YU46302A (sh) 2005-06-10
BR0016516A (pt) 2002-09-17
HRP20020536A2 (en) 2004-08-31
AU782920B2 (en) 2005-09-08
AR027035A1 (es) 2003-03-12
MXPA02006162A (es) 2002-12-05
RU2261862C2 (ru) 2005-10-10
WO2001046178A2 (en) 2001-06-28
NO20022927D0 (no) 2002-06-18
RU2002119557A (ru) 2004-01-10
KR100508741B1 (ko) 2005-08-17
CN1193027C (zh) 2005-03-16
PE20011098A1 (es) 2001-10-26
CA2394852A1 (en) 2001-06-28
AU3726701A (en) 2001-07-03
HUP0204572A3 (en) 2004-07-28
JO2199B1 (en) 2003-12-23
WO2001046178A3 (en) 2001-12-06
HUP0204572A2 (en) 2003-05-28
KR20020062365A (ko) 2002-07-25
NZ519359A (en) 2004-04-30

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20120528