US3834682A - Mixing column for medical humidifier and method of humidifying inhalable gases - Google Patents

Mixing column for medical humidifier and method of humidifying inhalable gases Download PDF

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Publication number
US3834682A
US3834682A US00264314A US26431472A US3834682A US 3834682 A US3834682 A US 3834682A US 00264314 A US00264314 A US 00264314A US 26431472 A US26431472 A US 26431472A US 3834682 A US3834682 A US 3834682A
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United States
Prior art keywords
column
liquid
gas
mixing
combination
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Expired - Lifetime
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US00264314A
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English (en)
Inventor
Phee C Mc
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American Hospital Supply Corp
Baxter International Inc
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American Hospital Supply Corp
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Filing date
Publication date
Application filed by American Hospital Supply Corp filed Critical American Hospital Supply Corp
Priority to US00264314A priority Critical patent/US3834682A/en
Priority to CA165,271A priority patent/CA999518A/en
Priority to AU53136/73A priority patent/AU480196B2/en
Priority to IT48806/73A priority patent/IT979847B/it
Priority to SE7304481A priority patent/SE405807B/sv
Priority to BE129506A priority patent/BE797603A/xx
Priority to CH474773A priority patent/CH552393A/de
Priority to FR7312061A priority patent/FR2189104B1/fr
Priority to ES413617A priority patent/ES413617A1/es
Priority to JP48052038A priority patent/JPS4951794A/ja
Priority to GB2683573A priority patent/GB1431558A/en
Priority to PH14707A priority patent/PH9850A/en
Priority to DE2329506A priority patent/DE2329506C3/de
Application granted granted Critical
Publication of US3834682A publication Critical patent/US3834682A/en
Assigned to BAXTER TRAVENOL LABORATORIES, INC. A CORP. OF DE reassignment BAXTER TRAVENOL LABORATORIES, INC. A CORP. OF DE MERGER (SEE DOCUMENT FOR DETAILS). EFFECTIVE ON 11/25/1985 ILLINOIS Assignors: AMERICAN HOSPITAL SUPPLY CORPORATION INTO
Assigned to BAXTER INTERNATIONAL INC. reassignment BAXTER INTERNATIONAL INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: BAXTER TRAVENOL LABORATOIRES, INC., A CORP. OF DE
Assigned to BAXTER INTERNATIONAL INC. reassignment BAXTER INTERNATIONAL INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). EFFECTIVE ON 10/17/1988 Assignors: BAXTER TRAVENOL LABORATORIES, INC., A CORP. OF DE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/16—Devices to humidify the respiration air
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/21—Mixing gases with liquids by introducing liquids into gaseous media
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/42—Reducing noise
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S261/00—Gas and liquid contact apparatus
    • Y10S261/65—Vaporizers

Definitions

  • ABSTRACT A multi-stage sieve plate humidifier column with a series of plastic snap together modular mixing units that combine to form an elongated vertical column with interconnected mixing chambers.
  • the column is confined inside a liquid supply bottle where it is submerged in a liquid used to humidlify an inhalable gas such as oxygen or air.
  • an inhalable gas such as oxygen or air.
  • the gas is bubbled into a lower portion of the submerged column, transferred through the interconnecting chambers of the column where the bubbles are broken up and mixed with liquid, and then the humidified gas collected near a top of the column and conducted to a patient for inhalation.
  • inhalation therapy has been used very extensively for treatment of emphysema and other lung and respiratory diseases, as well as postoperative treatment and cardiac patient care.
  • a breathable gas such as air or oxygen
  • This humidified gas is supplied to' a mask, nasal cannula, or tent where it is breathed by the patient and absorbed by his lungs.
  • a conventional medical humidifier system includes a dry gas source such as a portable oxygen tank or central oxygen supply system of a hospital, coupled with a container of humidifying liquid. Humidification in the past has been accomplished by atomizing the liquid into the gas or simply bubbling the gas into the liquid from an end of a submerged tube. Sometimes the end of the tube would have a porous gas diffusing covering.
  • the submerged mixing column with its series of stacked sieve plates repeatedly break up the gas bubbles into small bubbles to provide large gas-liquid innerface surface area for molecular transfer during the humidifying process.
  • This submerged mixing column has a unique construction in that it is formed of a series of modular snap together thermoplastic units.
  • the column formed in this way is sufficiently inexpensive so as to be confined in and become a permanent part of a liquid supply bottle. Once the contents of the bottle have been consumed to a desired level, the entire bottle, multi-stage mixing column, etc., are discarded. This reduces the risk of cross-contamination between patients.
  • the submerged stacked humidifier column with its multiple sieve plates also acts as a muffler to quiet the humidifying process. Instead of a loud gurgling noise,
  • FIG. 1 is a front elevational view partially in section showing the submerged modular humidifier column in the liquid supply bottle;
  • FIG. 2 is an enlarged sectional view of the lower three mixing chambers of the submerged humidifier column
  • FIG. 3 is a further enlarged sectional view of anindividual snap-together modular unit of the humidifier column
  • FIG. 4 is an enlarged sectional view of a bottom cap that snaps to the humidifier column
  • FIG. 5 is a cross sectional view taken along line 55 of FIG. 3;
  • FIG. 6 is a sectional view taken along line 66 of FIG. 1.
  • FIG. 1 shows the medical humidifier system connected for administering humidified gas to a patient.
  • the system includes a dry gas source 1 shown schematically in the form of a threaded nipple from an oxygen tank or oxygen wall supply line of a hospital.
  • a dual passage adapter 2 Connected to this dry gas source is a dual passage adapter 2 which is explained in more detail in my co-pending application entitled Port System for Medical Humidifier Container filed June 9, 1972, Ser. No. 264,315.
  • This adapter 2 is permanently connected at the time of use to a cap 3 of a liquid supply bottle 4 and this cap is in turn permanently connected to bottle 4.
  • adapter 2 can reliably support the bottle 4 from its cap 3 when the bottle is suspended from dry gas source 1 as shown in FIG. 1.
  • the FIG. 1 humidifier arrangement has a dry gas source I that feeds into a dry gas tube 15.
  • This dry gas tube 15 has an outlet 16 adjacent a bottom of the liquid filled container.
  • the term dry gas is used to distinguish oxygen air, etc., before it becomes humidified in the mixing column.
  • this dry gas tube 15 extends through a center axial portion of the stacked vertical column. Liquid from the bottle enters through a series of passages in a bottom cap portion 17 to at least partially fill the chambers 7 through 12. The number of chambers filled depends on the level of liquid in bottle 4. To insure that a sufficient portion of the humidifier column is always submerged for properhumidification an indented portion 55 indicates that the bottle should be replaced when the liquid in the bottle has been consumed down to this level.
  • the submerged multi-chambered humidifier column explained above is better shown in the'more enlarged view of FIG. 2.
  • the dry gas from a dry gas source 1 is fed through a dry gas column 15.
  • the bubbles move upwardly through the liquid 5 in the lowermost chamber 7. This causes the molecular liquid to diffuse across the liquid-gas interface of the bubble wall.
  • the dry gas thus takes on a higher humidity as expressed in FIG. 2 as H,.
  • the humidified gas then proceeds upwardly in the column through a porous sieve plate 18.
  • Sieve plate 18 has a series of holes that break up the large air bubbles that tend to form in an air pocket portion 22 of chamber 7.
  • Breaking up the bubbles in this way creates a very large number of small bubbles that have a greater surface area of the liquid-gas interface. This causes improved mixing and the gas picks up a higher humidity in chamber 8 as illustrated by H This process is repeated as the gas proceeds upwardly through the several stacked vertical chambers separated by sieve plates.
  • An advantage of breaking up the bubbles with a series of sieve plates rather than with a porous covering over a single outlet of a submerged tube is that the sieve plate bubbles have a very short half life and cause considerably less foaming in a liquid containing a bacteriastat, such as a paraben.
  • the humidified gas is collected and passes through a passage 25 where it is thereafter conducted through a tube 26 leading to a patient.
  • the patient can thus breathe the humidified gas with a very high relative humidity during inhalation therapy.
  • the previous medical humidifiers used essentially a one stage humidifying process by using the entire bottle contents as a mixing chamber. One process bubbled dry as into the liquid bottle. Another process used an atomizer inside the bottle. These previous humidifiers would gt the relative humidity to be approximately 60 to 75 percent when it was administered to a patient.
  • the applicants improved humidifier system can deliver humidified gas at relative humidities of approximately 82 percent. By more closely approximating the relative humidity of the respiratory tract, the patient suffers less drying of the mucous membrane.
  • the improved modular mixing column with the sieve plates shown in FIG. 2 also provide a very important advantage over previous one stage humidifiers.
  • the atomizing type humidifiers create an annoying wheezing sound.
  • the single chamber bubble type humidifiers cause an annoying gurgling or churning sound as the bubbles were free to migrate unbroken from the bottom of the container to atop liquid surface.
  • Such unrestricted bubbles tended to cling together and burst into large bubbles as they moved upwardly to cause a splashing and churning at a top surface of the liquid 5 when they broke through the liquid surface. Over long periods of time this caused a very annoying sound to the patient and the attending physicians and nurses.
  • FIG. 3 An individual modular unit 30 is shown in further enlarged sectional view of FIG. 3.
  • This unit 30 is shown in FIGS. 1 and 2 as defining the chamber 7.
  • This modular unit 30 includes a tubular outer wall 31 that has an upstanding flange 32 at its upper end and a downwardly extending flange 33 at its lower end.
  • These respective flanges include a groove 34- on an outer surface of flange 32 and an annular rib 35 on an inner surface of lower flange 33.
  • These two flanges also have respective tapered lead-in surfaces 36 and 37.
  • These flange structures are formed so that a series of identical modular units such as 30 can be snapped together into a vertical stacked column as shown in FIG. 2.
  • the top flange 32 of one modular unit mates a lower flange of a modular unit directly above.
  • Each modular unit includes a sieve plate 18 which is integral with tubular wall 31 and extends transversely across the chamber 7 of the modular unit.
  • the sieve plate includes a series of holes illustrated as 39 and 40 and the arrangement of these holes which break up the large bubbles of gas is shown in more detail in FIG. 5.
  • a dry gas tube segment 41 Integral with the sieve plate and concentrically disposed on a common longitudinal axis with a cylindrical outer wall 311 is a dry gas tube segment 41.
  • This dry gas tube segment includes an integral sleeve portion d2 adjacent its upper end.
  • This sleeve portion 42 has a receiving surface 43 that extends between a tapered leadin surface &4 and a stop shoulder 45.
  • a lower end of the dry gas tube segment includes an external tapered leadin surface 46.
  • a bottom cap 50 At a bottom of the multi-chambered mixing column is a bottom cap 50.
  • This bottom cap has an upstanding flange 51 of similar construction to upstanding flange 32.
  • a transverse bottom wall 52 of the bottom cap includes a series of holes 53 and 54.
  • This bottom cap 50 snaps into the bottom end of the lowermost modular mixing unit to form the bottom mixing chamber. Liquid 5 from the bottle enters the multi-stage mixing humidifier column through holes such as 53 ad 54.
  • FIG. 5 shows the arrangement of the holes in sieve plate 110.
  • atypical arrangement in the sieve plate includes two rings of holes with each hole being from 0.070 to 0.120 inch diameter. I have found holes in this range 0.093 inch diameter for example, are very effective in breaking up the large air bubbles while still providing sufficient opening for gas and liquid transfer across the sieve plates.
  • the hole arrangement in the bottom cap is shown in FIG. 6. Four holes such as 53 and 54 in bottom wall 52 are sufficient to supply the column with liquid. These holes are from 0.070 inch to 0.120 inch diameter.
  • the modular mixing units and bottom cap 50 I have found, snap together very effectively and form a sturdy vertical column when injection molded of a thermoplastic material such as polypropylene.
  • the injection molded modular unit of the humidifier column permit it to be made sufficiently inexpensive so it can be discarded after a single use.
  • an inhalation therapy humidifer comprising in combination:
  • a disposable container including an outer wall for defining a liquid-containing reservoir
  • a tubular multi-stage mixing column for containing gas therein fitting within container and spaced from said container wall and having a lower portion submerged in and communicating with said liquid
  • said column having means defining a plurality of series-interconnected gas-liquid mixing chamber for progressively humidifying the inhalation gas with the liquid as the gas ascends through the series of interconnecting mixing chambers in said column, said chambers being separated by a transverse partition common to adjacent chambers having a plurality of holes connecting adjacent chambers for breaking up inhalation gas into bubbles in the column to increase the gas-liquid interface, the chamber having tubular walls connected to and extending between said partitions and defining an independent conduit opening into the lower portion of said column, and communicating with said liquid in the column; said humidifier having a humidifiedgas outlet communicating with the uppermost chamber for directing humidified gas to a patient being treated.
  • conduit includes means for connecting a pressurized dry gas supply source with a lowermost chamber of the column.
  • An inhalation therapy humidifier comprising in combination: a container; a liquid at least partially filling said container; a multi-stage mixing column fitting within said container and having a portion submerged in said liquid, said column having a plurality of interconnected gas-liquid mixing chambers for humidifying the gas with the liquid as the gas passes through the interconnecting mixing chambers, each gas-liquid mixing chamber comprising a transverse sieve plate floor and a vertical tubular wall member connected to said sieve plate, each sieve plate and tubular wall member forming a modular mixing unit connected in vertically stacked relationship to similar units to form the multistage mixing column of the humidifier.
  • each modular gas-liquid mixing chamber has snap fit connecting means for attaching to a similar mixing unit.
  • the snap fit means includes an annular rib adjacent one end of the mixing unit and an annular groove adjacent an opposite end of the unit.
  • a modular mixing unit comprising a sieve plate; a tubular wall member connected to said sieve plate; and a dry gas feed tube attached to said unit formed by the tubular wall and sieve plate, said dry gas feed tube extending from an upper end to a lower end of the mixing unit; said unit having attachment means adjacent its upper end and adjacent its lower end; whereby a plurality of said mixing units can be vertically stacked and connected together at their attaching means to provide a multi-stage mixing column for liquid and gas.
  • tubular wall is cylindrical and has a central vertical longitudinal axis and the dry gas feed tube is co-axial with and concentrically disposed within the tubular wall, whereby modular mixing units can be connected together without rotationally orienting one relative to the other.
  • the dry gas tube connecting means includes an enlarged receiving sleeve connected with the sieve plate and this sleeve has an inwardly tapered lip surface, an internal annular receiving surface inside the sleeve having a diameter larger than the internal diameter of the gas tube, and a shoulder surface laterally extending from the annular receiving surface tothe dry gas tubes internal receiving surface; whereby the dry gas tubes of a series of modular mixing units fit together and provide an elongated dry gas feed line with a generally constant internal diameter.
  • the modular mixing unit includes a retention means adjacent a lower portion of its tubular wall for snap fitting with a retention means on an upstanding annular skirt of a modular mixing unit immediately therebelow.
  • a multi-stage mixing column for a disposable medical gas humidifier including a bottle with an outer wall forming a reservoir; a liquid at least partially filling said bottle a tubular column vertically depending into said bottle, spaced from said wall and having at least a lower portion thereof submerged in and communicating with said liquid; a series of vertically spaced, transverse perforated plates extending across and disposed within said column and defining series-connected chambers; a vertical dry gas tubular feed line of smaller cross sectional passage area than the mixing column axially disposed within said mixing column and extending through said perforated plates, so as to feed isolated pressurized dry gas axially from a top portion of the column through the various perforated plates to a bottom chamber of the column; connector means for attaching said dry gas feed line to a pressurized dry gas supply source; and connecting means for attaching an upper portion of the mixing column with a conduit for channeling humidifled gas from a top of the mixing column to a patient for inhalation therapy
  • the mixing column includes a bottom cap having at least one opening therethrough for passage of liquid into the column from within the bottle and surrounding the lowermost chamber of the mixing column.
  • a modular unit for constructing a multi-stage mixing column for liquid and gas comprising: a one piece integrally molded thermoplastic unit including a tubular housing wall and a transverse porous sieve plate extending across the housing wall; an internal dry gas tube formed with the sieve plate and housing wall; said housing wall and dry gas tube each including coupling means at their opposite ends for joining the unit to a similar one piece modular unit to form an elongated multi-compartment mixing column.
  • tubular housing wall includes a rib and groove construction for snap fitting two or more modular units together.
  • tubular housing wall has an upstanding annular flange adjacent its upper end which flange has an annular beveled wedge surface thereon.
  • tubular housing wall includes a depending annular flange adjacent its lower end with a beveled wedge surface thereon.
  • the gas tube includes a coupling member at an upper end, and said coupling member includes an enlarged receiver sleeve with an inwardly tapered upper lip surface, a transverse shoulder surface below said lip surface and an inner wall surface between the lip surface and shoulder surface; and said dry gas tube has a lower coupling portion that includes a tapered end surface adapted to engage the tapered lip surface of a dry gas tube receiving sleeve of an adjacent similar modular unit, whereby the modular units can be coupled to form a continuous dry gas feed line extending through a plurality of modular mixing units.
  • a method of humidifying a medical gas for direct administration to a patient during inhalation therapy comprising the steps of:

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US00264314A 1972-06-19 1972-06-19 Mixing column for medical humidifier and method of humidifying inhalable gases Expired - Lifetime US3834682A (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
US00264314A US3834682A (en) 1972-06-19 1972-06-19 Mixing column for medical humidifier and method of humidifying inhalable gases
CA165,271A CA999518A (en) 1972-06-19 1973-03-05 Mixing column for medical humidifier and method of humidifying inhalable gases
AU53136/73A AU480196B2 (en) 1972-06-19 1973-03-09 Mixing column for medical humidifier and method of humidifying inhalable gases
IT48806/73A IT979847B (it) 1972-06-19 1973-03-14 Perfezionamento negli inalatori in particolare negli umidificatori per detti
SE7304481A SE405807B (sv) 1972-06-19 1973-03-29 Fuktningsanordning for ett inhalationsterapisystem
BE129506A BE797603A (fr) 1972-06-19 1973-03-30 Colonne de melange pour humidificateur medical et procede en vue d'humidifier des gaz respirables
CH474773A CH552393A (de) 1972-06-19 1973-04-03 Befeuchter fuer die inhalationstherapie.
FR7312061A FR2189104B1 (de) 1972-06-19 1973-04-04
ES413617A ES413617A1 (es) 1972-06-19 1973-04-12 Un dispositivo humidificador para terapia por inhalacion.
JP48052038A JPS4951794A (de) 1972-06-19 1973-05-10
GB2683573A GB1431558A (en) 1972-06-19 1973-06-05 Medical humidifier for inhalation therapy
PH14707A PH9850A (en) 1972-06-19 1973-06-07 Mixing column for medical humidifier and method of humidifying inhalable gases
DE2329506A DE2329506C3 (de) 1972-06-19 1973-06-08 Medizinischer Befeuchter zur Inhalationsbehandlung

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Application Number Priority Date Filing Date Title
US00264314A US3834682A (en) 1972-06-19 1972-06-19 Mixing column for medical humidifier and method of humidifying inhalable gases

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US3834682A true US3834682A (en) 1974-09-10

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US00264314A Expired - Lifetime US3834682A (en) 1972-06-19 1972-06-19 Mixing column for medical humidifier and method of humidifying inhalable gases

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US (1) US3834682A (de)
JP (1) JPS4951794A (de)
BE (1) BE797603A (de)
CA (1) CA999518A (de)
CH (1) CH552393A (de)
DE (1) DE2329506C3 (de)
ES (1) ES413617A1 (de)
FR (1) FR2189104B1 (de)
GB (1) GB1431558A (de)
IT (1) IT979847B (de)
PH (1) PH9850A (de)
SE (1) SE405807B (de)

Cited By (45)

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US4045525A (en) * 1974-06-19 1977-08-30 Huggins James A Gas humidification apparatus
US4087495A (en) * 1976-03-25 1978-05-02 Mikuni Kogyo Kabushiki Kaisha Ultrasonic air humidifying apparatus
US4140735A (en) * 1977-08-15 1979-02-20 J. C. Schumacher Co. Process and apparatus for bubbling gas through a high purity liquid
US4269791A (en) * 1977-11-14 1981-05-26 The United States Of America As Represented By The Secretary Of The Navy Hydrogen-oxygen mixer apparatus and process
US4367182A (en) * 1981-07-14 1983-01-04 American Hospital Supply Corporation Container with incorporated aerator
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US20050051087A1 (en) * 2003-09-08 2005-03-10 Taiwan Semiconductor Manufacturing Co., Ltd., Primer tank with nozzle assembly
US20050181129A1 (en) * 2003-02-19 2005-08-18 Olander W. K. Sub-atmospheric pressure delivery of liquids, solids and low vapor pressure gases
WO2005079898A2 (de) * 2004-02-20 2005-09-01 Weinmann Geräte für Medizin GmbH & Co. KG Modulare vorrichtung zur befeuchtung von atemgas
US20050263075A1 (en) * 2003-07-23 2005-12-01 Luping Wang Delivery systems for efficient vaporization of precursor source material
US7300038B2 (en) 2002-07-23 2007-11-27 Advanced Technology Materials, Inc. Method and apparatus to help promote contact of gas with vaporized material
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WO2008131202A1 (en) * 2007-04-20 2008-10-30 Cardinal Health 212, Llc Acoustic attenuation chamber
US20100255198A1 (en) * 2006-08-31 2010-10-07 Advanced Technology Materials, Inc. Solid precursor-based delivery of fluid utilizing controlled solids morphology
CN101816988B (zh) * 2009-02-26 2012-06-13 崇仁科技事业股份有限公司 喷雾器
US20120152113A1 (en) * 2009-07-09 2012-06-21 Norecs Norwegian Electro Ceramics As Gas Humidification and Pressure Control
US20120204878A1 (en) * 2009-10-23 2012-08-16 Koninklijke Philips Electronics N.V. Patient interface device with adjustable headgear and frame
CN103143100A (zh) * 2013-02-25 2013-06-12 东莞英华融泰医疗科技有限公司 一种消声氧气湿化瓶
US20160108528A1 (en) * 2014-10-16 2016-04-21 Hsin-Yung Lin Gas generator
US20170312474A1 (en) * 2016-04-29 2017-11-02 Tania Forde Ingestible compositions system and method
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US10173194B2 (en) * 2014-07-03 2019-01-08 Chevron U.S.A. Inc. Systems for ionic liquid catalyzed alkylation based on a modular reactor
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US10385452B2 (en) 2012-05-31 2019-08-20 Entegris, Inc. Source reagent-based delivery of fluid with high material flux for batch deposition
US10384029B2 (en) 2009-11-18 2019-08-20 Fisher & Paykel Healthcare Limited Nasal interface
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US11033706B1 (en) 2020-05-26 2021-06-15 The Government of the United States of America, as represented by the Secretary of Homeland Security Inverted cylinder hydrostatic ventilator
US11179535B2 (en) 2008-10-10 2021-11-23 Fisher & Paykel Healthcare Limited Nasal pillows for a patient interface
US11253668B2 (en) 2016-03-16 2022-02-22 Fisher & Paykel Healthcare Limited Strap assembly, strap connector, headgear, headgear assembly, method of forming headgear, tubular connector, patient interface and method of joining straps
US11260194B2 (en) 2006-07-14 2022-03-01 Fisher & Paykel Healthcare Limited Breathing assistance apparatus
US11541197B2 (en) 2008-07-18 2023-01-03 Fisher & Paykel Healthcare Limited Breathing assistance apparatus
US11559655B2 (en) 2020-05-26 2023-01-24 The Government of the United States of America, as represented by the Secretary of Homeland Security Dual container hydrostatic ventilator
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Also Published As

Publication number Publication date
PH9850A (en) 1976-04-13
FR2189104B1 (de) 1979-01-12
ES413617A1 (es) 1975-12-16
JPS4951794A (de) 1974-05-20
FR2189104A1 (de) 1974-01-25
IT979847B (it) 1974-09-30
AU5313673A (en) 1974-09-12
CH552393A (de) 1974-08-15
DE2329506C3 (de) 1979-08-16
GB1431558A (en) 1976-04-07
SE405807B (sv) 1979-01-08
DE2329506A1 (de) 1974-01-17
CA999518A (en) 1976-11-09
BE797603A (fr) 1973-07-16
DE2329506B2 (de) 1978-12-14

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