UA95805C2 - Фармацевтичний препарат для перорального прийому з контрольованим вивільненням активного інгрідієнта в тонкому кишечнику і спосіб його одержання - Google Patents
Фармацевтичний препарат для перорального прийому з контрольованим вивільненням активного інгрідієнта в тонкому кишечнику і спосіб його одержанняInfo
- Publication number
- UA95805C2 UA95805C2 UAA200900169A UAA200900169A UA95805C2 UA 95805 C2 UA95805 C2 UA 95805C2 UA A200900169 A UAA200900169 A UA A200900169A UA A200900169 A UAA200900169 A UA A200900169A UA 95805 C2 UA95805 C2 UA 95805C2
- Authority
- UA
- Ukraine
- Prior art keywords
- active ingredient
- production
- oral administration
- small intestine
- pharmaceutical preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Винахід стосується фармацевтичного препарату для перорального прийому з контрольованим вивільненням активного інгредієнта в тонкому кишечнику на основі носіїв активного інгредієнта, забезпечених принаймні одним активним інгредієнтом, які забезпечені внутрішнім шаром, щоб контролювати вивільнення активного інгредієнта й шаром гастрорезистентного покриття, розташованим на ньому, причому внутрішній шар складається принаймні із двох дифузійних шарів, проникність яких для активного інгредієнта, що дифундує, зменшується від внутрішньої частини до зовнішньої, дифузійні шари утворені з матриксного матеріалу, який нерозчинний в рідині тонкого кишечнику і в який включені пороутворювачі, що контролюють проникність активного інгредієнта, що дифундує, і є розчинними та/або здатними до набрякання та/або абсорбції води в рідині тонкого кишечнику.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06014244A EP1880718B1 (de) | 2006-07-10 | 2006-07-10 | Pharmazeutische Zubereitung für die orale Verabreichung mit gesteuerter Wirkstofffreisetzung im Dünndarm und Verfahren zu ihrer Herstellung |
PCT/EP2007/005970 WO2008006506A1 (de) | 2006-07-10 | 2007-07-05 | Pharmazeutische zubereitung für die orale verabreichung mit gesteuerter wirkstofffreisetzung im dünndarm und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
UA95805C2 true UA95805C2 (uk) | 2011-09-12 |
Family
ID=37496994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200900169A UA95805C2 (uk) | 2006-07-10 | 2007-07-05 | Фармацевтичний препарат для перорального прийому з контрольованим вивільненням активного інгрідієнта в тонкому кишечнику і спосіб його одержання |
Country Status (22)
Country | Link |
---|---|
US (2) | US8221787B2 (uk) |
EP (1) | EP1880718B1 (uk) |
JP (1) | JP5424877B2 (uk) |
KR (1) | KR101451233B1 (uk) |
CN (1) | CN101495103B (uk) |
AR (1) | AR061860A1 (uk) |
AT (1) | ATE525065T1 (uk) |
CA (1) | CA2655838C (uk) |
CL (1) | CL2007002000A1 (uk) |
DK (1) | DK1880718T3 (uk) |
EA (1) | EA016683B1 (uk) |
ES (1) | ES2374158T3 (uk) |
HK (1) | HK1109858A1 (uk) |
HR (1) | HRP20110739T1 (uk) |
IL (1) | IL195931A (uk) |
JO (1) | JO2801B1 (uk) |
MX (1) | MX2009000379A (uk) |
PL (1) | PL1880718T3 (uk) |
SI (1) | SI1880718T1 (uk) |
TW (1) | TWI375573B (uk) |
UA (1) | UA95805C2 (uk) |
WO (1) | WO2008006506A1 (uk) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009130712A2 (en) * | 2008-04-22 | 2009-10-29 | Lupin Limited | Controlled release pharmaceutical compositions of trospium |
EP2133072A1 (en) | 2008-06-13 | 2009-12-16 | KRKA, D.D., Novo Mesto | Gastro-resistant pharmaceutical oral compositions comprising duloxetine or its pharmaceutically acceptable derivatives |
WO2010043408A2 (de) * | 2008-10-17 | 2010-04-22 | Ratiopharm Gmbh | Mikroverkapseltes fesoterodin |
DE102009001636A1 (de) * | 2009-03-18 | 2010-09-23 | Henkel Ag & Co. Kgaa | Bleichmittel mit verzögertem Bleichbeginn |
US20100303920A1 (en) * | 2009-05-27 | 2010-12-02 | Johan Hjartstam | Aqueous Film Coating Composition / 841 |
RU2014109079A (ru) * | 2011-08-12 | 2015-09-20 | Бёрингер Ингельхайм Ветмедика Гмбх | Фармацевтическая композиция с маскированным вкусом |
WO2013090893A1 (en) * | 2011-12-16 | 2013-06-20 | Celanese Eva Performance Polymers, Inc. | Gastroretentive controlled release vehicles that include ethylene copolymers, ethyl celluloses, and/or thermpoplastic polyurethanes |
JP2013145174A (ja) * | 2012-01-13 | 2013-07-25 | Panasonic Corp | 近接センサ |
PL2958607T3 (pl) * | 2013-05-02 | 2016-12-30 | Powłoka cewnika balonowego | |
JP6168673B2 (ja) * | 2015-10-07 | 2017-07-26 | 協和発酵キリン株式会社 | アリールアルキルアミン化合物含有医薬組成物 |
ITUA20161799A1 (it) * | 2016-03-18 | 2017-09-18 | Recordati Ind Chimica E Farmaceutica S P A | Composizione farmaceutica a rilascio prolungato comprendente cisteamina o un suo sale |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI101344B1 (fi) * | 1988-03-31 | 1998-06-15 | Tanabe Seiyaku Co | Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseuttisesti aktiivista ainetta |
US5840329A (en) * | 1997-05-15 | 1998-11-24 | Bioadvances Llc | Pulsatile drug delivery system |
ES2168043B1 (es) * | 1999-09-13 | 2003-04-01 | Esteve Labor Dr | Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido. |
JP3888064B2 (ja) * | 2000-01-27 | 2007-02-28 | 田辺製薬株式会社 | 徐放性製剤およびその製法 |
US20030018061A1 (en) * | 2000-01-28 | 2003-01-23 | Kohei Ogawa | Novel remedies with the use of beta 3 agonist |
DE10013029A1 (de) * | 2000-03-17 | 2001-09-20 | Roehm Gmbh | Mehrschichtige Arzneiform für die Colonfreigabe |
IN192159B (uk) * | 2000-05-15 | 2004-02-28 | Ranbaxy Lab Ltd | |
US7229665B2 (en) * | 2001-05-22 | 2007-06-12 | Millipore Corporation | Process of forming multilayered structures |
TR200300510A2 (tr) * | 2003-04-18 | 2004-11-22 | Sanovel �La� Sanay� Ve T�Caret A.�. | Dağılan alendronat mikropartikül formülasyonu |
DK2210605T3 (en) * | 2003-11-04 | 2017-05-22 | Tcd Royalty Sub Llc | Daily single dose doses of trospium. |
JP4771956B2 (ja) * | 2003-11-04 | 2011-09-14 | スパーナス ファーマシューティカルズ インコーポレイテッド | バイオアベイラビリティーエンハンサを含む第四級アンモニウム化合物の組成物 |
-
2006
- 2006-07-10 DK DK06014244.5T patent/DK1880718T3/da active
- 2006-07-10 AT AT06014244T patent/ATE525065T1/de active
- 2006-07-10 PL PL06014244T patent/PL1880718T3/pl unknown
- 2006-07-10 ES ES06014244T patent/ES2374158T3/es active Active
- 2006-07-10 SI SI200631131T patent/SI1880718T1/sl unknown
- 2006-07-10 EP EP06014244A patent/EP1880718B1/de active Active
-
2007
- 2007-06-27 TW TW096123213A patent/TWI375573B/zh not_active IP Right Cessation
- 2007-07-05 MX MX2009000379A patent/MX2009000379A/es active IP Right Grant
- 2007-07-05 JP JP2009518762A patent/JP5424877B2/ja not_active Expired - Fee Related
- 2007-07-05 UA UAA200900169A patent/UA95805C2/uk unknown
- 2007-07-05 EA EA200970100A patent/EA016683B1/ru not_active IP Right Cessation
- 2007-07-05 KR KR1020097002668A patent/KR101451233B1/ko not_active IP Right Cessation
- 2007-07-05 WO PCT/EP2007/005970 patent/WO2008006506A1/de active Application Filing
- 2007-07-05 CA CA2655838A patent/CA2655838C/en not_active Expired - Fee Related
- 2007-07-05 CN CN200780026301XA patent/CN101495103B/zh not_active Expired - Fee Related
- 2007-07-05 US US12/309,198 patent/US8221787B2/en not_active Expired - Fee Related
- 2007-07-08 JO JO2007271A patent/JO2801B1/en active
- 2007-07-09 CL CL2007002000A patent/CL2007002000A1/es unknown
- 2007-07-10 AR ARP070103054A patent/AR061860A1/es unknown
-
2008
- 2008-04-09 HK HK08103960.2A patent/HK1109858A1/xx not_active IP Right Cessation
- 2008-12-15 IL IL195931A patent/IL195931A/en not_active IP Right Cessation
-
2011
- 2011-10-12 HR HR20110739T patent/HRP20110739T1/hr unknown
-
2012
- 2012-06-15 US US13/525,029 patent/US20120294938A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AR061860A1 (es) | 2008-09-24 |
CA2655838C (en) | 2014-04-08 |
CN101495103A (zh) | 2009-07-29 |
JO2801B1 (en) | 2014-03-15 |
CN101495103B (zh) | 2013-05-22 |
EA016683B1 (ru) | 2012-06-29 |
IL195931A0 (en) | 2009-09-01 |
JP2009542742A (ja) | 2009-12-03 |
EP1880718B1 (de) | 2011-09-21 |
IL195931A (en) | 2014-02-27 |
JP5424877B2 (ja) | 2014-02-26 |
ES2374158T3 (es) | 2012-02-14 |
WO2008006506A1 (de) | 2008-01-17 |
HRP20110739T1 (hr) | 2011-11-30 |
US8221787B2 (en) | 2012-07-17 |
DK1880718T3 (da) | 2011-11-21 |
ATE525065T1 (de) | 2011-10-15 |
CA2655838A1 (en) | 2008-01-17 |
KR20090029830A (ko) | 2009-03-23 |
SI1880718T1 (sl) | 2011-11-30 |
MX2009000379A (es) | 2009-04-14 |
KR101451233B1 (ko) | 2014-10-15 |
PL1880718T3 (pl) | 2012-02-29 |
US20120294938A1 (en) | 2012-11-22 |
TWI375573B (en) | 2012-11-01 |
HK1109858A1 (en) | 2008-06-27 |
CL2007002000A1 (es) | 2008-01-18 |
TW200808381A (en) | 2008-02-16 |
EA200970100A1 (ru) | 2009-06-30 |
EP1880718A1 (de) | 2008-01-23 |
US20090285891A1 (en) | 2009-11-19 |
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