UA85541C2 - Карбаматные производные хинуклидина и фармацевтическая композиции, которая содержит эти соединения - Google Patents

Карбаматные производные хинуклидина и фармацевтическая композиции, которая содержит эти соединения

Info

Publication number
UA85541C2
UA85541C2 UAA200500504A UA2005000504A UA85541C2 UA 85541 C2 UA85541 C2 UA 85541C2 UA A200500504 A UAA200500504 A UA A200500504A UA 2005000504 A UA2005000504 A UA 2005000504A UA 85541 C2 UA85541 C2 UA 85541C2
Authority
UA
Ukraine
Prior art keywords
pharmaceutical compositions
same
compositions containing
carbamate derivatives
quinuclidine carbamate
Prior art date
Application number
UAA200500504A
Other languages
English (en)
Ukrainian (uk)
Inventor
Киньонес Мария Прат
Альберо Мария Антония Буил
Форнер Мария Долорс Фернандес
Original Assignee
Лабораториос Алмиралл, С. А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лабораториос Алмиралл, С. А. filed Critical Лабораториос Алмиралл, С. А.
Publication of UA85541C2 publication Critical patent/UA85541C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

В заявке описываются карбаматы формулы (І):или их фармацевтически приемлемые соли, включая четвертичные аммониевые соли формулы (II):,а также способы их получения, фармацевтические композиции, которые содержат эти соединения, и их применение для терапевтического лечения в качестве антагонистов М3 мускариновых рецепторов.
UAA200500504A 2002-06-21 2003-06-18 Карбаматные производные хинуклидина и фармацевтическая композиции, которая содержит эти соединения UA85541C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200201439A ES2203327B1 (es) 2002-06-21 2002-06-21 Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.

Publications (1)

Publication Number Publication Date
UA85541C2 true UA85541C2 (ru) 2009-02-10

Family

ID=29797397

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200500504A UA85541C2 (ru) 2002-06-21 2003-06-18 Карбаматные производные хинуклидина и фармацевтическая композиции, которая содержит эти соединения

Country Status (21)

Country Link
US (3) US7435742B2 (ru)
EP (1) EP1515968A2 (ru)
JP (1) JP2005533799A (ru)
CN (1) CN100363363C (ru)
AR (1) AR040275A1 (ru)
AU (1) AU2003279384A1 (ru)
BR (1) BR0312169A (ru)
CA (1) CA2490082A1 (ru)
EC (1) ECSP045484A (ru)
ES (1) ES2203327B1 (ru)
IL (1) IL165775A0 (ru)
MX (1) MXPA04012272A (ru)
NO (1) NO20050217L (ru)
NZ (1) NZ537252A (ru)
PE (1) PE20040579A1 (ru)
RU (1) RU2321588C2 (ru)
TW (1) TW200401776A (ru)
UA (1) UA85541C2 (ru)
UY (1) UY27850A1 (ru)
WO (1) WO2004000840A2 (ru)
ZA (1) ZA200410211B (ru)

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PE20020719A1 (es) 2000-12-22 2002-10-11 Almirall Prodesfarma Ag Derivados de carbamato de quinuclidina como agentes antimuscarinicos m3
ES2203327B1 (es) 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.
ES2204295B1 (es) 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
KR101287460B1 (ko) * 2004-04-22 2013-07-23 베링거 인겔하임 인터내셔날 게엠베하 벤즈옥사진을 함유하는 호흡기 질환 치료용 약제학적배합물
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
EP1765339A4 (en) * 2004-06-30 2009-09-02 Glaxo Group Ltd ANTAGONISTS OF MUSCARIN ACETYLCHOLIN RECEPTOR
ES2246170B1 (es) * 2004-07-29 2007-04-01 Almirall Prodesfarma, S.A. Nuevo procedimiento para preparar derivados de carbamato de quinuclidinio.
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
MX2008001976A (es) 2005-08-15 2008-03-25 Boehringer Ingelheim Int Procedimiento para la preparacion de betamimeticos.
DE102006028286A1 (de) * 2006-06-20 2007-12-27 Wirsich, Konrad, Dipl.-Ing. (FH) Drehmoment- und rutschfest verbundene aus zwei Teilen bestehende Schaltzahnräder
EP1882691A1 (en) 2006-07-26 2008-01-30 CHIESI FARMACEUTICI S.p.A. Quinuclidine derivatives as M3 antagonists
WO2008096870A1 (ja) * 2007-02-09 2008-08-14 Astellas Pharma Inc. アザ架橋環化合物
WO2008103426A1 (en) * 2007-02-23 2008-08-28 Theravance, Inc. Quaternary ammonium diphenylmethyl compounds useful as muscarinic receptor antagonists
EP2065385A1 (en) * 2007-11-28 2009-06-03 Laboratorios SALVAT, S.A. Stable crystalline salt of (R)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester
EP2080507A1 (en) * 2008-01-15 2009-07-22 CHIESI FARMACEUTICI S.p.A. Pharmaceutical formulations comprising an anticholinergic drug
MX2012008703A (es) * 2010-01-28 2012-11-12 Theron Pharmaceuticals Inc Derivados de 7-azoniabiciclo [2.2.1] heptano, sus metodos de produccion y usos farmaceuticos.
BR112013023774B1 (pt) * 2011-03-18 2022-01-11 Genzyme Corporation Inibidores de glicosilceramida sintase
EP2631674A1 (de) * 2012-02-23 2013-08-28 ELMOS Semiconductor AG Verfahren und Sensorsystem zur Vermessung der Eigenschaften einer Übertragungsstrecke eines Messsystems zwischen Sender und Empfänger
MA37975B2 (fr) 2012-09-11 2021-03-31 Genzyme Corp Inhibiteurs de synthase de glucosylcéramide
JP6218940B2 (ja) * 2013-07-13 2017-10-25 ベイジン エフエスウェルカム テクノロジー ディベロップメント カンパニー リミテッド キニン系化合物、その光学異性体及びその製造方法と医薬用途
US10570127B1 (en) 2018-11-05 2020-02-25 Renexxion, Llc Material and methods for the treatment of gastro-intestinal disorders
TW202220648A (zh) 2020-07-24 2022-06-01 美商健臻公司 包含芬谷司他(venglustat)之醫藥組合物
JPWO2022145408A1 (ru) * 2020-12-28 2022-07-07

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US2762796A (en) 1956-09-11 Iminodibenzyl derivative
GB1219606A (en) 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
GB1246606A (en) 1969-04-28 1971-09-15 Starogardzkie Zakl Farma Dibenzo-azepine derivatives
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KR100944580B1 (ko) 2001-12-20 2010-02-25 치에시 파마슈티시 에스.피.아. 1-알킬-1-아조니아비시클로[2.2.2]옥탄 카르바메이트유도체 및 이의 무스카린 수용체 길항제로서의 용도
ES2203327B1 (es) 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.
ES2204295B1 (es) 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.

Also Published As

Publication number Publication date
ES2203327A1 (es) 2004-04-01
AR040275A1 (es) 2005-03-23
WO2004000840A2 (en) 2003-12-31
UY27850A1 (es) 2003-11-28
TW200401776A (en) 2004-02-01
EP1515968A2 (en) 2005-03-23
MXPA04012272A (es) 2005-04-08
CN100363363C (zh) 2008-01-23
NZ537252A (en) 2006-07-28
RU2321588C2 (ru) 2008-04-10
ES2203327B1 (es) 2005-06-16
WO2004000840A3 (en) 2004-02-19
ECSP045484A (es) 2005-01-28
US20090054480A1 (en) 2009-02-26
BR0312169A (pt) 2005-03-29
AU2003279384A1 (en) 2004-01-06
JP2005533799A (ja) 2005-11-10
PE20040579A1 (es) 2004-09-08
CN1675206A (zh) 2005-09-28
IL165775A0 (en) 2006-01-15
US7435742B2 (en) 2008-10-14
US20060094751A1 (en) 2006-05-04
ZA200410211B (en) 2005-09-06
US20090005412A1 (en) 2009-01-01
NO20050217L (no) 2005-03-18
CA2490082A1 (en) 2003-12-31
RU2005101409A (ru) 2005-11-20

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