UA8025A1 - Спосіб отримання антибактеріального розчину - Google Patents
Спосіб отримання антибактеріального розчинуInfo
- Publication number
- UA8025A1 UA8025A1 UA3790651A UA3790651A UA8025A1 UA 8025 A1 UA8025 A1 UA 8025A1 UA 3790651 A UA3790651 A UA 3790651A UA 3790651 A UA3790651 A UA 3790651A UA 8025 A1 UA8025 A1 UA 8025A1
- Authority
- UA
- Ukraine
- Prior art keywords
- manufacturing antibacterial
- antibacterial solution
- lactic
- manufacturing
- piperasinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Спосіб одержання антибактеріального розчину включає змішування піперазиніл-вмісного похідного хінолону у вигляді молочнокислої солі з водою при рН 2,5-7. З метою підвищення стабільності до седиментації розчину до молочнокислої солі або її гідрату додається кислота, вибрана з групи, що включає молочну, бурштинову, метансульфокислоту, соляну або пропіонову.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833333719 DE3333719A1 (de) | 1983-09-17 | 1983-09-17 | Loesungen milchsaurer salze von piperazinylchinolon- und piperazinyl-azachinoloncarbonsaeuren |
Publications (1)
Publication Number | Publication Date |
---|---|
UA8025A1 true UA8025A1 (uk) | 1995-12-26 |
Family
ID=6209428
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA3790651A UA8025A1 (uk) | 1983-09-17 | 1984-09-14 | Спосіб отримання антибактеріального розчину |
Country Status (24)
Country | Link |
---|---|
US (3) | US4705789A (uk) |
EP (1) | EP0138018B1 (uk) |
JP (1) | JPS6094910A (uk) |
KR (1) | KR870001958B1 (uk) |
AU (1) | AU562507B2 (uk) |
CA (1) | CA1228547A (uk) |
DD (1) | DD227882A5 (uk) |
DE (2) | DE3333719A1 (uk) |
DK (1) | DK162811C (uk) |
ES (1) | ES8607021A1 (uk) |
FI (1) | FI83286C (uk) |
GR (1) | GR80364B (uk) |
HK (1) | HK74789A (uk) |
HU (1) | HU194733B (uk) |
IE (1) | IE57905B1 (uk) |
IL (1) | IL72953A (uk) |
NO (1) | NO171765C (uk) |
NZ (1) | NZ209548A (uk) |
PL (1) | PL144897B1 (uk) |
PT (1) | PT79206B (uk) |
SG (1) | SG21489G (uk) |
SU (1) | SU1384187A3 (uk) |
UA (1) | UA8025A1 (uk) |
ZA (1) | ZA847267B (uk) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3608745A1 (de) * | 1985-07-24 | 1987-01-29 | Bayer Ag | Bakterizide zubereitungen zur anwendung auf dem gebiet der veterinaermedizin |
DE3537761A1 (de) * | 1985-10-24 | 1987-04-30 | Bayer Ag | Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure |
IL80459A (en) * | 1986-10-30 | 1991-04-15 | Abic Ltd | Water-soluble adduct of norfloxacin and nicotinic acid |
JPH0696533B2 (ja) * | 1987-01-14 | 1994-11-30 | 北陸製薬株式会社 | キノロンカルボン酸の水性組成物 |
DE3713672A1 (de) * | 1987-04-24 | 1988-11-17 | Bayer Ag | Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren |
JPH01175935A (ja) * | 1987-12-28 | 1989-07-12 | Kyorin Pharmaceut Co Ltd | 凍結乾燥注射剤 |
DE3902079A1 (de) * | 1988-04-15 | 1989-10-26 | Bayer Ag | I.m. injektionsformen von gyrase-inhibitoren |
US5225413A (en) * | 1988-09-16 | 1993-07-06 | Bayer-Aktiengesellschaft | pH-neutral aqueous solutions of quinolone-carboxylic acids |
NZ232091A (en) * | 1989-01-16 | 1990-12-21 | Bellon Labor Sa Roger | 7-fluoro-8-(piperazin-1-yl)-4-oxo-1,4-dihydro-benzo(b)(1,8)naphthyridine-3-carboxylic acid derivatives, preparation and pharmaceutical compositions thereof |
JP3153549B2 (ja) * | 1989-12-29 | 2001-04-09 | アボツト・ラボラトリーズ | キノロンカルボン酸―金属イオン―酸錯体 |
KR0159540B1 (ko) * | 1992-01-21 | 1998-12-01 | 김정순 | 퀴놀론-카복실산의 염 및 그 함유조성물 |
TW254855B (uk) * | 1993-07-28 | 1995-08-21 | Otsuka Pharma Co Ltd | |
ES2127036B1 (es) * | 1994-03-21 | 1999-11-16 | Ind Quimica Agropecuaria S A | Aducto de norfloxacina soluble en agua. |
KR960000223A (ko) * | 1994-06-08 | 1996-01-25 | 김정순 | 신규한 피리돈 카르복실산 화합물을 함유한 수용액 및 이의 제조방법 |
ES2088742B1 (es) * | 1994-06-29 | 1997-03-16 | Salvat Lab Sa | Composicion antibiotica de aplicacion otica. |
JPH08213881A (ja) * | 1995-02-02 | 1996-08-20 | Fujitsu Ltd | 周波数制御回路 |
DE19730023A1 (de) * | 1997-07-11 | 1999-01-14 | Bayer Ag | Hochreine Ciprofloxacin-Infusion |
IN186245B (uk) | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
KR20010032194A (ko) | 1998-09-18 | 2001-04-16 | 요시다 쇼지 | 피리돈카르복실을 용해시키는 방법, 이 산을 용해시키는용해제, 이 산을 함유하는 수용액 제제, 및 이를 제조하는방법 |
DE102004005186B3 (de) * | 2004-02-02 | 2005-10-13 | Krka Tovarna Zdravil, D.D. | Verfahren zur Herstellung von gereinigtem Ciprofloxacin |
DE102004054873A1 (de) * | 2004-11-12 | 2006-05-18 | Bayer Healthcare Ag | Behandlung von Mastitis |
DE102005055385A1 (de) * | 2004-12-09 | 2006-06-14 | Bayer Healthcare Ag | Arzneimittel zur hygienischen Applikation im Ohr |
MX2007006908A (es) * | 2004-12-09 | 2007-08-03 | Bayer Healthcare Ag | Estabilizacion de esteres de glucocorticoides con acidos. |
US8877945B2 (en) | 2009-05-15 | 2014-11-04 | Redx Pharma Limited | Redox drug derivatives |
CN103479569A (zh) * | 2013-01-14 | 2014-01-01 | 四川喜亚动物药业有限公司 | 兽用环丙沙星注射液及其制备方法 |
WO2016094588A2 (en) | 2014-12-09 | 2016-06-16 | Heflin John A | Spine alignment system |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE296839C (uk) * | ||||
CH296839A (de) * | 1944-03-14 | 1954-02-28 | Knoll Ag | Verfahren zur Herstellung von haltbaren, wässrigen Lösungen von Salzen von Strychninoxyd. |
DE2047486A1 (de) * | 1970-09-26 | 1972-03-30 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren zur Stabilisierung einer pynthioxinhaltigen, wässerigen Injektions lösung |
US4022894A (en) * | 1975-03-03 | 1977-05-10 | Fainberg Samuel M | Stable solution of benzthiazide (3-[benzythiol methyl]-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide) suitable for parenteral administration and process of preparation |
JPS6019910B2 (ja) * | 1979-10-11 | 1985-05-18 | 大塚製薬株式会社 | ベンゾ〔ij〕キノリジン−2−カルボン酸誘導体及びその製造法 |
JPS5531028A (en) * | 1978-08-25 | 1980-03-05 | Dai Ichi Seiyaku Co Ltd | Injection |
AR223983A1 (es) * | 1978-08-25 | 1981-10-15 | Dainippon Pharmaceutical Co | Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico |
DE2918319A1 (de) * | 1979-05-07 | 1980-11-13 | Roehm Pharma Gmbh | Therapeutische verabreichungsform |
JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
JPS57188515A (en) * | 1981-05-13 | 1982-11-19 | Kyoto Yakuhin Kogyo Kk | Stabilized aqueous dopamine preparation |
HU188181B (en) * | 1981-06-11 | 1986-03-28 | Warner-Lambert Co,Us | Process for producing salts of naphtiridine and quinoline compounds of antimicrobial activity |
-
1983
- 1983-09-17 DE DE19833333719 patent/DE3333719A1/de not_active Withdrawn
-
1984
- 1984-08-27 US US06/644,834 patent/US4705789A/en not_active Expired - Lifetime
- 1984-09-04 DE DE8484110474T patent/DE3474915D1/de not_active Expired
- 1984-09-04 EP EP84110474A patent/EP0138018B1/de not_active Expired
- 1984-09-04 NO NO843518A patent/NO171765C/no not_active IP Right Cessation
- 1984-09-11 ES ES535832A patent/ES8607021A1/es not_active Expired
- 1984-09-12 AU AU32976/84A patent/AU562507B2/en not_active Expired
- 1984-09-13 FI FI843587A patent/FI83286C/fi not_active IP Right Cessation
- 1984-09-13 JP JP59190760A patent/JPS6094910A/ja active Granted
- 1984-09-14 HU HU843476A patent/HU194733B/hu unknown
- 1984-09-14 IE IE2347/84A patent/IE57905B1/en not_active IP Right Cessation
- 1984-09-14 PL PL1984249591A patent/PL144897B1/pl unknown
- 1984-09-14 DD DD84267297A patent/DD227882A5/de not_active IP Right Cessation
- 1984-09-14 PT PT79206A patent/PT79206B/pt not_active IP Right Cessation
- 1984-09-14 GR GR80364A patent/GR80364B/el unknown
- 1984-09-14 NZ NZ209548A patent/NZ209548A/en unknown
- 1984-09-14 DK DK441084A patent/DK162811C/da not_active IP Right Cessation
- 1984-09-14 SU SU843790651A patent/SU1384187A3/ru active
- 1984-09-14 CA CA000463155A patent/CA1228547A/en not_active Expired
- 1984-09-14 IL IL72953A patent/IL72953A/xx unknown
- 1984-09-14 UA UA3790651A patent/UA8025A1/uk unknown
- 1984-09-14 ZA ZA847267A patent/ZA847267B/xx unknown
- 1984-09-15 KR KR1019840005635A patent/KR870001958B1/ko not_active IP Right Cessation
-
1986
- 1986-05-12 US US06/862,343 patent/US4808585A/en not_active Expired - Lifetime
-
1987
- 1987-07-09 US US07/071,459 patent/US4808583A/en not_active Expired - Lifetime
-
1989
- 1989-04-08 SG SG214/89A patent/SG21489G/en unknown
- 1989-09-14 HK HK747/89A patent/HK74789A/xx not_active IP Right Cessation
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