TWI414523B - 用於治療糖尿病及代謝病症之雜環受體促效劑 - Google Patents

用於治療糖尿病及代謝病症之雜環受體促效劑 Download PDF

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Publication number
TWI414523B
TWI414523B TW96150669A TW96150669A TWI414523B TW I414523 B TWI414523 B TW I414523B TW 96150669 A TW96150669 A TW 96150669A TW 96150669 A TW96150669 A TW 96150669A TW I414523 B TWI414523 B TW I414523B
Authority
TW
Taiwan
Prior art keywords
thiazol
phenoxymethyl
tetrazol
group
hexahydropyridin
Prior art date
Application number
TW96150669A
Other languages
English (en)
Chinese (zh)
Other versions
TW200833688A (en
Inventor
Xin Chen
Peng Cheng
L Edward Clemens
Jeffrey D Johnson
Jingyuan Ma
Alison Murphy
Imad Nashashibi
Christopher J Rabbat
Jiangao Song
Maria E Wilson
Yan Zhu
Zuchun Zhao
Original Assignee
Metabolex Inc
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40261614&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI414523(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Metabolex Inc filed Critical Metabolex Inc
Publication of TW200833688A publication Critical patent/TW200833688A/zh
Application granted granted Critical
Publication of TWI414523B publication Critical patent/TWI414523B/zh

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
TW96150669A 2006-12-28 2007-12-27 用於治療糖尿病及代謝病症之雜環受體促效劑 TWI414523B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87790306P 2006-12-28 2006-12-28

Publications (2)

Publication Number Publication Date
TW200833688A TW200833688A (en) 2008-08-16
TWI414523B true TWI414523B (zh) 2013-11-11

Family

ID=40261614

Family Applications (1)

Application Number Title Priority Date Filing Date
TW96150669A TWI414523B (zh) 2006-12-28 2007-12-27 用於治療糖尿病及代謝病症之雜環受體促效劑

Country Status (5)

Country Link
CN (1) CN101616586B (es)
AR (1) AR064702A1 (es)
CL (1) CL2007003841A1 (es)
TW (1) TWI414523B (es)
ZA (1) ZA200904281B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638541B2 (en) 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
US20090270404A1 (en) * 2008-03-31 2009-10-29 Metabolex, Inc. Oxymethylene aryl compounds and uses thereof
CN102666553B (zh) 2009-10-01 2015-05-06 赛马拜制药公司 取代的四唑-1-基-苯氧基甲基-噻唑-2-基-哌啶基-嘧啶盐
JP5960683B2 (ja) * 2010-04-28 2016-08-02 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ 殺真菌剤としてのケトヘテロアリールピペリジンおよび−ピペラジン誘導体
BR112012032248A2 (pt) * 2010-06-23 2016-09-13 Metabolex Inc composições de 5-etil-2-{4-[-4(-4-tetrazol-1-il-fenoximetil)-tiazol-2-il]-piperidin-1-il}-pirimidina
CN103467398B (zh) * 2013-09-03 2015-01-21 浙江医药高等专科学校 ***酰胺类化合物、其制备方法和其抗糖尿病用途
WO2015101957A2 (en) * 2014-01-06 2015-07-09 Rhizen Pharmaceuticals Sa Novel glutaminase inhibitors
US10292983B2 (en) 2016-08-03 2019-05-21 Cymabay Therapeutics, Inc. Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions
CN111072652B (zh) * 2018-10-19 2023-05-23 暨南大学 用于治疗糖尿病和/或相关病症的化合物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005061489A1 (en) * 2003-12-24 2005-07-07 Prosidion Limited Heterocyclic derivatives as gpcr receptor agonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1829718A (zh) * 2003-07-14 2006-09-06 艾尼纳制药公司 作为新陈代谢调节剂的稠合芳基和杂芳基衍生物以及预防和治疗与其相关的病症

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005061489A1 (en) * 2003-12-24 2005-07-07 Prosidion Limited Heterocyclic derivatives as gpcr receptor agonists

Also Published As

Publication number Publication date
CN101616586B (zh) 2014-08-13
CN101616586A (zh) 2009-12-30
ZA200904281B (en) 2010-08-25
TW200833688A (en) 2008-08-16
AR064702A1 (es) 2009-04-22
CL2007003841A1 (es) 2008-03-14

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