TW200833688A - Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders - Google Patents

Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders

Info

Publication number
TW200833688A
TW200833688A TW96150669A TW96150669A TW200833688A TW 200833688 A TW200833688 A TW 200833688A TW 96150669 A TW96150669 A TW 96150669A TW 96150669 A TW96150669 A TW 96150669A TW 200833688 A TW200833688 A TW 200833688A
Authority
TW
Taiwan
Prior art keywords
diabetes
treatment
receptor agonists
metabolic disorders
heterocyclic
Prior art date
Application number
TW96150669A
Other languages
Chinese (zh)
Other versions
TWI414523B (en
Inventor
Xin Chen
Peng Cheng
Edward L Clemens
Jeffrey D Johnson
Jing-Yuan Ma
Alison Murphy
Imad Nashashibi
Christopher J Rabbat
Jiangao Song
Maria E Wilson
Yan Zhu
Zuchun Zhao
Original Assignee
Metabolex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40261614&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200833688(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Metabolex Inc filed Critical Metabolex Inc
Publication of TW200833688A publication Critical patent/TW200833688A/en
Application granted granted Critical
Publication of TWI414523B publication Critical patent/TWI414523B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.
TW96150669A 2006-12-28 2007-12-27 Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders TWI414523B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87790306P 2006-12-28 2006-12-28

Publications (2)

Publication Number Publication Date
TW200833688A true TW200833688A (en) 2008-08-16
TWI414523B TWI414523B (en) 2013-11-11

Family

ID=40261614

Family Applications (1)

Application Number Title Priority Date Filing Date
TW96150669A TWI414523B (en) 2006-12-28 2007-12-27 Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders

Country Status (5)

Country Link
CN (1) CN101616586B (en)
AR (1) AR064702A1 (en)
CL (1) CL2007003841A1 (en)
TW (1) TWI414523B (en)
ZA (1) ZA200904281B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638541B2 (en) 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
EP2280704B1 (en) * 2008-03-31 2015-05-13 Cymabay Therapeutics, Inc. Oxymethylene aryl compounds and uses thereof
ES2497566T3 (en) 2009-10-01 2014-09-23 Cymabay Therapeutics, Inc. Tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
WO2011134969A1 (en) * 2010-04-28 2011-11-03 Bayer Cropscience Ag Ketoheteroarylpiperidine and ketoheteroarylpiperazine derivates as fungicides
WO2011163090A1 (en) * 2010-06-23 2011-12-29 Metabolex, Inc. Compositions of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
CN103467398B (en) * 2013-09-03 2015-01-21 浙江医药高等专科学校 Triazole amide compounds, and preparation method and application thereof in resisting diabetes
US9783533B2 (en) * 2014-01-06 2017-10-10 Rhizen Pharmaceuticals Sa Glutaminase inhibitors
AU2017305392A1 (en) 2016-08-03 2019-02-21 Cymabay Therapeutics, Inc. Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions
CN111072652B (en) * 2018-10-19 2023-05-23 暨南大学 Compounds for the treatment of diabetes and/or related disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1829718A (en) * 2003-07-14 2006-09-06 艾尼纳制药公司 Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
WO2005061489A1 (en) * 2003-12-24 2005-07-07 Prosidion Limited Heterocyclic derivatives as gpcr receptor agonists

Also Published As

Publication number Publication date
CL2007003841A1 (en) 2008-03-14
TWI414523B (en) 2013-11-11
CN101616586B (en) 2014-08-13
CN101616586A (en) 2009-12-30
ZA200904281B (en) 2010-08-25
AR064702A1 (en) 2009-04-22

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