TW430642B - Substituted diaryldicarboxylic acid diguanidides, processes for their preparation, their use as a medicament or diagnostic, and medicament containing them - Google Patents

Substituted diaryldicarboxylic acid diguanidides, processes for their preparation, their use as a medicament or diagnostic, and medicament containing them

Info

Publication number
TW430642B
TW430642B TW086100957A TW86100957A TW430642B TW 430642 B TW430642 B TW 430642B TW 086100957 A TW086100957 A TW 086100957A TW 86100957 A TW86100957 A TW 86100957A TW 430642 B TW430642 B TW 430642B
Authority
TW
Taiwan
Prior art keywords
medicament
radicals
processes
diagnostic
substituted
Prior art date
Application number
TW086100957A
Other languages
English (en)
Inventor
Heinz-Werner Kleemann
Joachim Brendel
Jan-Robert Schwark
Andreas Weichert
Hans Jochen Lang
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of TW430642B publication Critical patent/TW430642B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/60—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
TW086100957A 1996-01-31 1997-01-29 Substituted diaryldicarboxylic acid diguanidides, processes for their preparation, their use as a medicament or diagnostic, and medicament containing them TW430642B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19603425A DE19603425A1 (de) 1996-01-31 1996-01-31 Substituierte Diaryldicarbonsäure-diguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
TW430642B true TW430642B (en) 2001-04-21

Family

ID=7784136

Family Applications (1)

Application Number Title Priority Date Filing Date
TW086100957A TW430642B (en) 1996-01-31 1997-01-29 Substituted diaryldicarboxylic acid diguanidides, processes for their preparation, their use as a medicament or diagnostic, and medicament containing them

Country Status (19)

Country Link
EP (1) EP0787717A1 (zh)
JP (1) JPH09221465A (zh)
KR (1) KR970059165A (zh)
AR (1) AR005596A1 (zh)
AU (1) AU1239097A (zh)
BR (1) BR9700817A (zh)
CA (1) CA2196388A1 (zh)
CZ (1) CZ27197A3 (zh)
DE (1) DE19603425A1 (zh)
HR (1) HRP970057A2 (zh)
HU (1) HUP9700277A3 (zh)
IL (1) IL120093A0 (zh)
NO (1) NO970406L (zh)
NZ (1) NZ314145A (zh)
PL (1) PL317844A1 (zh)
SK (1) SK12797A3 (zh)
TR (1) TR199700059A2 (zh)
TW (1) TW430642B (zh)
ZA (1) ZA97770B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10024319A1 (de) * 2000-05-17 2001-11-22 Merck Patent Gmbh Bisacylguanidine
AR065785A1 (es) * 2007-03-19 2009-07-01 Xenon Pharmaceuticals Inc Compuestos biarilo y biheteroarilo de utilidad en el tratamiento de trastornos de hierro

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (de) 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
DE59302959D1 (de) 1992-02-15 1996-07-25 Hoechst Ag 3,5-Substituierte Benzoylguanidine, mit antiarrythmischer Wirkung und inhibierender Wirkung auf die Proliferationen von Zellen
US5278933A (en) 1992-06-30 1994-01-11 Hunsinger Terrance D Fiber optic splice organizer and associated method
EP0604852A1 (de) * 1992-12-28 1994-07-06 Hoechst Aktiengesellschaft 2,4-Substituierte 5-(N-substituierte-Sulfamoyl)-Benzoylguanidine, als Antiarrythmika, Inhibitoren der Proliferationen von Zellen, und Inhibitoren des Natrium-Protonen-Antiporters
IL109570A0 (en) * 1993-05-17 1994-08-26 Fujisawa Pharmaceutical Co Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof
DE4327244A1 (de) * 1993-08-13 1995-02-16 Hoechst Ag Harnstoffsubstituierte Benzoylguandine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
DE19603425A1 (de) 1997-08-07
JPH09221465A (ja) 1997-08-26
HU9700277D0 (en) 1997-03-28
NO970406L (no) 1997-08-01
NZ314145A (en) 1997-11-24
SK12797A3 (en) 1998-02-04
AR005596A1 (es) 1999-06-23
TR199700059A2 (tr) 1997-08-21
HUP9700277A2 (en) 1997-10-28
IL120093A0 (en) 1997-04-15
AU1239097A (en) 1997-08-07
NO970406D0 (no) 1997-01-30
CZ27197A3 (cs) 1998-05-13
ZA97770B (en) 1997-07-31
EP0787717A1 (de) 1997-08-06
HUP9700277A3 (en) 1998-04-28
KR970059165A (ko) 1997-08-12
HRP970057A2 (en) 1998-04-30
PL317844A1 (en) 1997-08-04
CA2196388A1 (en) 1997-08-01
BR9700817A (pt) 1998-07-07

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