US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
US3896111A
(en)
|
1973-02-20 |
1975-07-22 |
Research Corp |
Ansa macrolides
|
US4151042A
(en)
|
1977-03-31 |
1979-04-24 |
Takeda Chemical Industries, Ltd. |
Method for producing maytansinol and its derivatives
|
US4137230A
(en)
|
1977-11-14 |
1979-01-30 |
Takeda Chemical Industries, Ltd. |
Method for the production of maytansinoids
|
USRE30985E
(en)
|
1978-01-01 |
1982-06-29 |
|
Serum-free cell culture media
|
US4265814A
(en)
|
1978-03-24 |
1981-05-05 |
Takeda Chemical Industries |
Matansinol 3-n-hexadecanoate
|
US4307016A
(en)
|
1978-03-24 |
1981-12-22 |
Takeda Chemical Industries, Ltd. |
Demethyl maytansinoids
|
JPS5562090A
(en)
|
1978-10-27 |
1980-05-10 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
JPS5566585A
(en)
|
1978-11-14 |
1980-05-20 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
JPS55164687A
(en)
|
1979-06-11 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
US4256746A
(en)
|
1978-11-14 |
1981-03-17 |
Takeda Chemical Industries |
Dechloromaytansinoids, their pharmaceutical compositions and method of use
|
JPS55102583A
(en)
|
1979-01-31 |
1980-08-05 |
Takeda Chem Ind Ltd |
20-acyloxy-20-demethylmaytansinoid compound
|
JPS55162791A
(en)
|
1979-06-05 |
1980-12-18 |
Takeda Chem Ind Ltd |
Antibiotic c-15003pnd and its preparation
|
JPS55164685A
(en)
|
1979-06-08 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
JPS55164686A
(en)
|
1979-06-11 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
US4309428A
(en)
|
1979-07-30 |
1982-01-05 |
Takeda Chemical Industries, Ltd. |
Maytansinoids
|
JPS5645483A
(en)
|
1979-09-19 |
1981-04-25 |
Takeda Chem Ind Ltd |
C-15003phm and its preparation
|
EP0028683A1
(en)
|
1979-09-21 |
1981-05-20 |
Takeda Chemical Industries, Ltd. |
Antibiotic C-15003 PHO and production thereof
|
JPS5645485A
(en)
|
1979-09-21 |
1981-04-25 |
Takeda Chem Ind Ltd |
Production of c-15003pnd
|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
US4376110A
(en)
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
WO1982001188A1
(en)
|
1980-10-08 |
1982-04-15 |
Takeda Chemical Industries Ltd |
4,5-deoxymaytansinoide compounds and process for preparing same
|
US4450254A
(en)
|
1980-11-03 |
1984-05-22 |
Standard Oil Company |
Impact improvement of high nitrile resins
|
US4419446A
(en)
|
1980-12-31 |
1983-12-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant DNA process utilizing a papilloma virus DNA as a vector
|
US4315929A
(en)
|
1981-01-27 |
1982-02-16 |
The United States Of America As Represented By The Secretary Of Agriculture |
Method of controlling the European corn borer with trewiasine
|
US4313946A
(en)
|
1981-01-27 |
1982-02-02 |
The United States Of America As Represented By The Secretary Of Agriculture |
Chemotherapeutically active maytansinoids from Trewia nudiflora
|
JPS57192389A
(en)
|
1981-05-20 |
1982-11-26 |
Takeda Chem Ind Ltd |
Novel maytansinoid
|
US4596792A
(en)
|
1981-09-04 |
1986-06-24 |
The Regents Of The University Of California |
Safe vaccine for hepatitis containing polymerized serum albumin
|
US4741900A
(en)
|
1982-11-16 |
1988-05-03 |
Cytogen Corporation |
Antibody-metal ion complexes
|
US4601978A
(en)
|
1982-11-24 |
1986-07-22 |
The Regents Of The University Of California |
Mammalian metallothionein promoter system
|
US4560655A
(en)
|
1982-12-16 |
1985-12-24 |
Immunex Corporation |
Serum-free cell culture medium and process for making same
|
US4657866A
(en)
|
1982-12-21 |
1987-04-14 |
Sudhir Kumar |
Serum-free, synthetic, completely chemically defined tissue culture media
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4767704A
(en)
|
1983-10-07 |
1988-08-30 |
Columbia University In The City Of New York |
Protein-free culture medium
|
US4599231A
(en)
|
1984-03-09 |
1986-07-08 |
Scripps Clinic And Research Foundation |
Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
|
US4599230A
(en)
|
1984-03-09 |
1986-07-08 |
Scripps Clinic And Research Foundation |
Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
|
US4965199A
(en)
|
1984-04-20 |
1990-10-23 |
Genentech, Inc. |
Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
|
US4970198A
(en)
|
1985-10-17 |
1990-11-13 |
American Cyanamid Company |
Antitumor antibiotics (LL-E33288 complex)
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
US4601903A
(en)
|
1985-05-01 |
1986-07-22 |
The United States Of America As Represented By The Department Of Health And Human Services |
Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease
|
GB8516415D0
(en)
|
1985-06-28 |
1985-07-31 |
Celltech Ltd |
Culture of animal cells
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
US4927762A
(en)
|
1986-04-01 |
1990-05-22 |
Cell Enterprises, Inc. |
Cell culture medium with antioxidant
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
US5075109A
(en)
|
1986-10-24 |
1991-12-24 |
Southern Research Institute |
Method of potentiating an immune response
|
US5811128A
(en)
|
1986-10-24 |
1998-09-22 |
Southern Research Institute |
Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
|
US4886499A
(en)
|
1986-12-18 |
1989-12-12 |
Hoffmann-La Roche Inc. |
Portable injection appliance
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
US5079233A
(en)
|
1987-01-30 |
1992-01-07 |
American Cyanamid Company |
N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
AU600575B2
(en)
|
1987-03-18 |
1990-08-16 |
Sb2, Inc. |
Altered antibodies
|
US4849222A
(en)
|
1987-03-24 |
1989-07-18 |
The Procter & Gamble Company |
Mixtures for treating hypercholesterolemia
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
US4975278A
(en)
|
1988-02-26 |
1990-12-04 |
Bristol-Myers Company |
Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
|
US5004697A
(en)
|
1987-08-17 |
1991-04-02 |
Univ. Of Ca |
Cationized antibodies for delivery through the blood-brain barrier
|
US5053394A
(en)
|
1988-09-21 |
1991-10-01 |
American Cyanamid Company |
Targeted forms of methyltrithio antitumor agents
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
US5770701A
(en)
|
1987-10-30 |
1998-06-23 |
American Cyanamid Company |
Process for preparing targeted forms of methyltrithio antitumor agents
|
JP2670680B2
(ja)
|
1988-02-24 |
1997-10-29 |
株式会社ビーエムジー |
生理活性物質含有ポリ乳酸系微小球およびその製造法
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
JPH01287029A
(ja)
|
1988-05-13 |
1989-11-17 |
Mect Corp |
新規抗ウィルス剤
|
EP0435911B1
(en)
|
1988-09-23 |
1996-03-13 |
Cetus Oncology Corporation |
Cell culture medium for enhanced cell growth, culture longevity and product expression
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
EP0739904A1
(en)
|
1989-06-29 |
1996-10-30 |
Medarex, Inc. |
Bispecific reagents for aids therapy
|
US5690938A
(en)
|
1989-07-07 |
1997-11-25 |
Oravax, Inc. |
Oral immunization with multiple particulate antigen delivery system
|
US5518725A
(en)
|
1989-09-25 |
1996-05-21 |
University Of Utah Research Foundation |
Vaccine compositions and method for induction of mucosal immune response via systemic vaccination
|
CA2026147C
(en)
|
1989-10-25 |
2006-02-07 |
Ravi J. Chari |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
US5238843A
(en)
*
|
1989-10-27 |
1993-08-24 |
Genencor International, Inc. |
Method for cleaning a surface on which is bound a glycoside-containing substance
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
DE69120146T2
(de)
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
US5061620A
(en)
|
1990-03-30 |
1991-10-29 |
Systemix, Inc. |
Human hematopoietic stem cell
|
US5268164A
(en)
|
1990-04-23 |
1993-12-07 |
Alkermes, Inc. |
Increasing blood-brain barrier permeability with permeabilizer peptides
|
US5112596A
(en)
|
1990-04-23 |
1992-05-12 |
Alkermes, Inc. |
Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability
|
CZ288492B6
(en)
|
1990-04-24 |
2001-06-13 |
Biota Scient Management |
Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon
|
WO1991016073A1
(en)
|
1990-04-24 |
1991-10-31 |
The University Of Newcastle Research Associates Limited |
Oral vaccine comprising antigen surface-associated with red blood cells
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
EP0547065B1
(en)
|
1990-06-29 |
2001-08-29 |
Large Scale Biology Corporation |
Melanin production by transformed microorganisms
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
EP0814159B1
(en)
|
1990-08-29 |
2005-07-27 |
GenPharm International, Inc. |
Transgenic mice capable of producing heterologous antibodies
|
US5714374A
(en)
|
1990-09-12 |
1998-02-03 |
Rutgers University |
Chimeric rhinoviruses
|
US5122469A
(en)
|
1990-10-03 |
1992-06-16 |
Genentech, Inc. |
Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
|
WO1992006691A1
(en)
|
1990-10-19 |
1992-04-30 |
Biota Scientific Management Pty. Ltd. |
Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus
|
US5264365A
(en)
|
1990-11-09 |
1993-11-23 |
Board Of Regents, The University Of Texas System |
Protease-deficient bacterial strains for production of proteolytically sensitive polypeptides
|
US5508192A
(en)
|
1990-11-09 |
1996-04-16 |
Board Of Regents, The University Of Texas System |
Bacterial host strains for producing proteolytically sensitive polypeptides
|
WO1992009690A2
(en)
|
1990-12-03 |
1992-06-11 |
Genentech, Inc. |
Enrichment method for variant proteins with altered binding properties
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
AU1991592A
(en)
|
1991-04-30 |
1992-12-21 |
Alkermes, Inc. |
Cationized antibodies against intracellular proteins
|
LU91067I2
(fr)
|
1991-06-14 |
2004-04-02 |
Genentech Inc |
Trastuzumab et ses variantes et dérivés immuno chimiques y compris les immotoxines
|
GB9114948D0
(en)
|
1991-07-11 |
1991-08-28 |
Pfizer Ltd |
Process for preparing sertraline intermediates
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
CA2116774C
(en)
|
1991-09-19 |
2003-11-11 |
Paul J. Carter |
Expression in e. coli antibody fragments having at least a cysteine present as a free thiol. use for the production of bifunctional f(ab') 2 antibodies
|
EP0605522B1
(en)
|
1991-09-23 |
1999-06-23 |
Medical Research Council |
Methods for the production of humanized antibodies
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
US5362852A
(en)
|
1991-09-27 |
1994-11-08 |
Pfizer Inc. |
Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
|
US5587458A
(en)
|
1991-10-07 |
1996-12-24 |
Aronex Pharmaceuticals, Inc. |
Anti-erbB-2 antibodies, combinations thereof, and therapeutic and diagnostic uses thereof
|
US5288502A
(en)
|
1991-10-16 |
1994-02-22 |
The University Of Texas System |
Preparation and uses of multi-phase microspheres
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
DE69229880T2
(de)
|
1991-11-19 |
2000-05-04 |
The University Of Virginia Patent Foundation, Charlottesville |
Kombinierte virustatikum-antimediator-behandlung (covam) von gewöhnlichen erkältungen
|
JPH0826057B2
(ja)
|
1992-01-16 |
1996-03-13 |
株式会社ディ・ディ・エス研究所 |
シアル酸オリゴ糖誘導体及び微粒子キャリヤー
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
DE69333807T2
(de)
|
1992-02-06 |
2006-02-02 |
Chiron Corp., Emeryville |
Marker für krebs und biosynthetisches bindeprotein dafür
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
US5326856A
(en)
|
1992-04-09 |
1994-07-05 |
Cytogen Corporation |
Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding
|
ZA932522B
(en)
|
1992-04-10 |
1993-12-20 |
Res Dev Foundation |
Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
|
JP2904647B2
(ja)
|
1992-06-12 |
1999-06-14 |
株式会社蛋白工学研究所 |
5−ブロム−4−クロロインド−3−イル−2−シアル酸の製造方法
|
CA2137558A1
(en)
|
1992-07-17 |
1994-02-03 |
Wayne A. Marasco |
Method of intracellular binding of target molecules
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
WO1994002178A1
(en)
|
1992-07-27 |
1994-02-03 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Targeting of liposomes to the blood-brain barrier
|
WO1994004690A1
(en)
|
1992-08-17 |
1994-03-03 |
Genentech, Inc. |
Bispecific immunoadhesins
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
US5849716A
(en)
|
1992-10-22 |
1998-12-15 |
Kirin Beer Kabushiki Kaisha |
Sphingoglycolipids, their preparation, and therapeutic methods of use
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
US5807722A
(en)
|
1992-10-30 |
1998-09-15 |
Bioengineering Resources, Inc. |
Biological production of acetic acid from waste gases with Clostridium ljungdahlii
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
ES2091684T3
(es)
|
1992-11-13 |
1996-11-01 |
Idec Pharma Corp |
Aplicacion terapeutica de anticuerpos quimericos y radiomarcados contra el antigeno de diferenciacion restringida de los linfocitos b humanos para el tratamiento del linfoma de las celulas b.
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
JP3523285B2
(ja)
*
|
1993-01-22 |
2004-04-26 |
雪印乳業株式会社 |
糖分解酵素の製造法
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
US5374541A
(en)
|
1993-05-04 |
1994-12-20 |
The Scripps Research Institute |
Combined use of β-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides
|
US20020037517A1
(en)
|
1993-05-28 |
2002-03-28 |
Hutchens T. William |
Methods for sequencing biopolymers
|
WO1994029351A2
(en)
|
1993-06-16 |
1994-12-22 |
Celltech Limited |
Antibodies
|
WO1995011010A1
(en)
|
1993-10-22 |
1995-04-27 |
Genentech, Inc. |
Methods and compositions for microencapsulation of antigens for use as vaccines
|
US5369017A
(en)
|
1994-02-04 |
1994-11-29 |
The Scripps Research Institute |
Process for solid phase glycopeptide synthesis
|
WO1995023157A1
(en)
|
1994-02-25 |
1995-08-31 |
E.I. Du Pont De Nemours And Company |
4-n-substituted sialic acids and their sialosides
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
US5622701A
(en)
|
1994-06-14 |
1997-04-22 |
Protein Design Labs, Inc. |
Cross-reacting monoclonal antibodies specific for E- and P-selectin
|
AU3272695A
(en)
|
1994-08-12 |
1996-03-07 |
Immunomedics Inc. |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
US5639635A
(en)
|
1994-11-03 |
1997-06-17 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
EP1241264A1
(en)
|
1994-12-02 |
2002-09-18 |
Chiron Corporation |
Monoclonal antibodies to colon cancer antigen
|
US5663149A
(en)
|
1994-12-13 |
1997-09-02 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
US6673533B1
(en)
|
1995-03-10 |
2004-01-06 |
Meso Scale Technologies, Llc. |
Multi-array multi-specific electrochemiluminescence testing
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
WO1996036436A1
(en)
|
1995-04-25 |
1996-11-21 |
Irori |
Remotely programmable matrices with memories and uses thereof
|
JP4312259B2
(ja)
|
1995-04-27 |
2009-08-12 |
アムジェン フレモント インク. |
免疫したゼノマウス(XenoMouse)に由来するヒト抗体
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
US5712374A
(en)
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
US5837234A
(en)
|
1995-06-07 |
1998-11-17 |
Cytotherapeutics, Inc. |
Bioartificial organ containing cells encapsulated in a permselective polyether suflfone membrane
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
US6265150B1
(en)
|
1995-06-07 |
2001-07-24 |
Becton Dickinson & Company |
Phage antibodies
|
CA2227871A1
(en)
|
1995-07-26 |
1997-02-13 |
Maxim Pharmaceuticals, Inc. |
Mucosal delivery of polynucleotides
|
DE19544393A1
(de)
|
1995-11-15 |
1997-05-22 |
Hoechst Schering Agrevo Gmbh |
Synergistische herbizide Mischungen
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
WO1997038123A1
(en)
|
1996-04-05 |
1997-10-16 |
Board Of Regents, The University Of Texas System |
Methods for producing soluble, biologically-active disulfide bond-containing eukaryotic proteins in bacterial cells
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
US5922845A
(en)
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
US6340702B1
(en)
|
1996-07-22 |
2002-01-22 |
Sankyo Company, Limited |
Neuraminic acid derivatives, their preparation and their medical use
|
US6506564B1
(en)
|
1996-07-29 |
2003-01-14 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses therefor
|
NZ335368A
(en)
|
1996-11-14 |
2001-08-31 |
Biota Scient Management |
Macromolecular compound with one or more neuraminidase binders, binds to the active site of influenza virus neuraminidase
|
CA2722378C
(en)
|
1996-12-03 |
2015-02-03 |
Amgen Fremont Inc. |
Human antibodies that bind tnf.alpha.
|
TW555562B
(en)
|
1996-12-27 |
2003-10-01 |
Kirin Brewery |
Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
|
ES2268776T3
(es)
|
1997-04-18 |
2007-03-16 |
Novartis Ag |
Neoglicoproteinas.
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
US6083715A
(en)
|
1997-06-09 |
2000-07-04 |
Board Of Regents, The University Of Texas System |
Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
|
JPH1135593A
(ja)
|
1997-07-18 |
1999-02-09 |
Daikin Ind Ltd |
2−フルオロフコシル−n−アロイルグルコサミン誘導体及びその中間物、並びにそれらの製造方法
|
TW480247B
(en)
|
1997-12-12 |
2002-03-21 |
Gilead Sciences Inc |
Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
AU765703B2
(en)
|
1998-03-27 |
2003-09-25 |
Bruce J. Bryan |
Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
|
ES2532910T3
(es)
|
1998-04-02 |
2015-04-01 |
Genentech, Inc. |
Variantes de anticuerpos y fragmentos de los mismos
|
EP2180007B2
(en)
|
1998-04-20 |
2017-08-30 |
Roche Glycart AG |
Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
|
US6455571B1
(en)
|
1998-04-23 |
2002-09-24 |
Abbott Laboratories |
Inhibitors of neuraminidases
|
ES2198913T5
(es)
|
1998-05-06 |
2013-11-18 |
Genentech, Inc. |
Purificación de proteínas mediante cromatografía de intercambio iónico
|
US6528286B1
(en)
|
1998-05-29 |
2003-03-04 |
Genentech, Inc. |
Mammalian cell culture process for producing glycoproteins
|
JP3773153B2
(ja)
|
1998-05-29 |
2006-05-10 |
独立行政法人理化学研究所 |
シアル酸誘導体
|
ATE234468T1
(de)
|
1998-09-18 |
2003-03-15 |
Massachusetts Inst Technology |
Biologische verwendungen von halbleitenden nanokristallen
|
FR2783523B1
(fr)
*
|
1998-09-21 |
2006-01-20 |
Goemar Lab Sa |
Fuco-oligosaccharides, enzyme pour leur preparation a partir des fucanes, bacterie productrice de l'enzyme et applications des fuco-oligosaccharides a la protection des plantes
|
US6994966B2
(en)
|
2000-02-17 |
2006-02-07 |
Glycominds Ltd. |
Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
|
US6696304B1
(en)
|
1999-02-24 |
2004-02-24 |
Luminex Corporation |
Particulate solid phase immobilized protein quantitation
|
AUPP913999A0
(en)
|
1999-03-12 |
1999-04-01 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
US7090973B1
(en)
*
|
1999-04-09 |
2006-08-15 |
Oscient Pharmaceuticals Corporation |
Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics
|
US7854934B2
(en)
|
1999-08-20 |
2010-12-21 |
Sloan-Kettering Institute For Cancer Research |
Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
AUPQ422399A0
(en)
|
1999-11-24 |
1999-12-16 |
University Of New South Wales, The |
Method of screening transformed or transfected cells
|
US6727356B1
(en)
|
1999-12-08 |
2004-04-27 |
Epoch Pharmaceuticals, Inc. |
Fluorescent quenching detection reagents and methods
|
US7019129B1
(en)
|
2000-05-09 |
2006-03-28 |
Biosearch Technologies, Inc. |
Dark quenchers for donor-acceptor energy transfer
|
US7863020B2
(en)
|
2000-06-28 |
2011-01-04 |
Glycofi, Inc. |
Production of sialylated N-glycans in lower eukaryotes
|
US6514221B2
(en)
|
2000-07-27 |
2003-02-04 |
Brigham And Women's Hospital, Inc. |
Blood-brain barrier opening
|
US20020065259A1
(en)
|
2000-08-30 |
2002-05-30 |
Schatzberg Alan F. |
Glucocorticoid blocking agents for increasing blood-brain barrier permeability
|
AUPR001000A0
(en)
|
2000-09-08 |
2000-10-05 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
US7034036B2
(en)
|
2000-10-30 |
2006-04-25 |
Pain Therapeutics, Inc. |
Inhibitors of ABC drug transporters at the blood-brain barrier
|
US20030083299A1
(en)
|
2000-11-04 |
2003-05-01 |
Ferguson Ian A. |
Non-invasive delivery of polypeptides through the blood-brain barrier
|
JP2002153272A
(ja)
|
2000-11-24 |
2002-05-28 |
Inst Of Physical & Chemical Res |
生体分子マイクロアレイ
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
WO2002086096A2
(en)
|
2001-01-23 |
2002-10-31 |
University Of Rochester Medical Center |
Methods of producing or identifying intrabodies in eukaryotic cells
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
DE10121982B4
(de)
|
2001-05-05 |
2008-01-24 |
Lts Lohmann Therapie-Systeme Ag |
Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung
|
JP2002371087A
(ja)
|
2001-06-15 |
2002-12-26 |
Mitsubishi Chemicals Corp |
有機ホスホン酸
|
DE60234057D1
(de)
|
2001-07-25 |
2009-11-26 |
Raptor Pharmaceutical Inc |
Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
|
ES2338218T3
(es)
|
2001-07-25 |
2010-05-05 |
Facet Biotech Corporation |
Formulacion farmacologica liofilizada estable de anticuerpos igg daclizumab.
|
JP2005500336A
(ja)
|
2001-07-25 |
2005-01-06 |
ニューヨーク・ユニバーシティ |
感染および癌に対するワクチンのためのアジュバントとしてのグリコシルセラミドの使用
|
IL160170A0
(en)
|
2001-08-03 |
2004-07-25 |
Glycart Biotechnology Ag |
A host cell engineered to produce a polypeptide having increased cytotoxicity
|
NZ532027A
(en)
|
2001-10-10 |
2008-09-26 |
Neose Technologies Inc |
Remodeling and glycoconjugation of peptides
|
KR20040077655A
(ko)
|
2001-10-19 |
2004-09-06 |
슈페리어 마이크로파우더스 엘엘씨 |
전자 형상 증착용 테잎 조성물
|
AUPR879601A0
(en)
|
2001-11-09 |
2001-12-06 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
US20040024293A1
(en)
|
2001-11-21 |
2004-02-05 |
Matthew Lawrence |
Methods and systems for analyzing complex biological systems
|
RU2004127458A
(ru)
|
2002-02-14 |
2005-10-27 |
Иммуномедикс, Инк. (Us) |
Анти-cd20 антитела, их гибридные белки и способы их использования
|
US20030162695A1
(en)
|
2002-02-27 |
2003-08-28 |
Schatzberg Alan F. |
Glucocorticoid blocking agents for increasing blood-brain barrier permeability
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
AU2003219277A1
(en)
|
2002-03-14 |
2003-09-29 |
Medical Research Council |
Intracellular antibodies
|
MXPA04011249A
(es)
|
2002-05-14 |
2005-06-06 |
Chiron Srl |
Vacunas mucosales con adyuvante de quitosano y antigenos meningococicos.
|
ES2325495T3
(es)
|
2002-07-08 |
2009-09-07 |
Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. |
Moleculas hibridas de macrolidos con moleculas anti-inflamatorias esteroideas y no esteroideas.
|
US20080070324A1
(en)
|
2002-07-15 |
2008-03-20 |
Floyd Alton D |
Quantity control device for microscope slide staining assays
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
US20040062682A1
(en)
|
2002-09-30 |
2004-04-01 |
Rakow Neal Anthony |
Colorimetric sensor
|
DK3284753T3
(da)
|
2002-10-17 |
2021-07-05 |
Genmab As |
Humane monoklonale antistoffer mod cd20 til anvendelse i behandlingen af multipel sclerose
|
CN100386068C
(zh)
|
2002-12-03 |
2008-05-07 |
布朗歇特洛克菲勒神经科学研究所 |
传输物质穿过血脑屏障的人工低密度脂蛋白载体
|
EP1572744B1
(en)
|
2002-12-16 |
2010-06-09 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
WO2004063351A2
(en)
|
2003-01-09 |
2004-07-29 |
Macrogenics, Inc. |
IDENTIFICATION AND ENGINEERING OF ANTIBODIES WITH VARIANT Fc REGIONS AND METHODS OF USING SAME
|
SG2013005590A
(en)
*
|
2003-01-22 |
2015-06-29 |
Roche Glycart Ag |
Fusion constructs and use of same to produce antibodies with increased fc receptor binding affinity and effector function
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
AR044388A1
(es)
|
2003-05-20 |
2005-09-07 |
Applied Molecular Evolution |
Moleculas de union a cd20
|
US20040259142A1
(en)
|
2003-06-04 |
2004-12-23 |
Imperial College Innovations Limited |
Products and methods
|
CA2528669A1
(en)
|
2003-06-09 |
2005-01-20 |
The Regents Of The University Of Michigan |
Compositions and methods for treating and diagnosing cancer
|
JP4148844B2
(ja)
|
2003-06-11 |
2008-09-10 |
ソニー・エリクソン・モバイルコミュニケーションズ株式会社 |
情報端末装置及び音声付画像ファイルの出力方法
|
EP2292264A3
(en)
*
|
2003-07-24 |
2012-12-19 |
Innate Pharma |
Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds
|
JP2007501811A
(ja)
|
2003-08-08 |
2007-02-01 |
ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト |
治療的な関心対象のタンパク質に対する遅延分子の選択的な化学物質接合のためのガラクトースオキシダーゼの使用。
|
WO2005025511A2
(en)
|
2003-09-10 |
2005-03-24 |
Cedars-Sinai Medical Center |
Potassium channel mediated delivery of agents through the blood-brain barrier
|
ATE493157T1
(de)
|
2003-09-15 |
2011-01-15 |
Smart Tech Lp |
Implantate mit befestigten silylierten therapeutischen mitteln
|
WO2005030258A2
(en)
|
2003-09-22 |
2005-04-07 |
Acidophil Llc |
Small molecule compositions and methods for increasing drug efficiency using compositions thereof
|
US7019288B2
(en)
|
2003-09-30 |
2006-03-28 |
Sequenom, Inc. |
Methods of making substrates for mass spectrometry analysis and related devices
|
US20050221337A1
(en)
|
2003-10-02 |
2005-10-06 |
Massachusetts Institute Of Technology |
Microarrays and microspheres comprising oligosaccharides, complex carbohydrates or glycoproteins
|
ES2550311T3
(es)
|
2003-11-05 |
2015-11-06 |
Roche Glycart Ag |
Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas
|
CA3062320C
(en)
|
2003-11-06 |
2022-11-15 |
Seattle Genetics, Inc. |
Monomethylvaline compounds capable of conjugation to ligands
|
US20050255491A1
(en)
|
2003-11-13 |
2005-11-17 |
Lee Frank D |
Small molecule and peptide arrays and uses thereof
|
WO2005088310A2
(en)
|
2004-03-05 |
2005-09-22 |
The Scripps Research Institute |
High throughput glycan microarrays
|
US20050221397A1
(en)
|
2004-03-30 |
2005-10-06 |
Northern Advancement Center For Science & Technology |
RM2 antigen (beta1,4-GalNAc-disialyl-Lc4) as prostate cancer-associated antigen
|
EP1740946B1
(en)
|
2004-04-20 |
2013-11-06 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
ITMI20040928A1
(it)
|
2004-05-07 |
2004-08-07 |
Uni Di Bologna Dipartiment O D |
Procedura per la preparazione di coniugati della doxorubicina con l'albumina umana lattosaminata
|
JP2008504531A
(ja)
|
2004-06-24 |
2008-02-14 |
ザ スクリップス リサーチ インスティテュート |
切断可能なリンカーを有するアレイ
|
KR20190035967A
(ko)
|
2004-07-22 |
2019-04-03 |
제넨테크, 인크. |
Her2 항체 조성물
|
US8022043B2
(en)
|
2004-08-27 |
2011-09-20 |
Albert Einstein College Of Medicine Of Yeshiva University |
Ceramide derivatives as modulators of immunity and autoimmunity
|
WO2006060171A2
(en)
|
2004-11-16 |
2006-06-08 |
Board Of Regents, The University Of Texas System |
Methods and compositions related to phage-nanoparticle assemblies
|
WO2006055925A2
(en)
|
2004-11-19 |
2006-05-26 |
Swiss Federal Institute Of Technology |
Microarrays for analyte detection
|
WO2006064983A1
(en)
|
2004-12-14 |
2006-06-22 |
Korea Research Institute Of Bioscience And Biotechnology |
Monoclonal antibody specific human embryonic stem cell
|
EP1833489A4
(en)
|
2004-12-28 |
2011-08-03 |
Univ Rockefeller |
GLYCOLIPIDS AND RELATED ANALOGUES AS ANTIGENS OF NKT LYMPHOCYTES
|
US7923013B2
(en)
|
2004-12-28 |
2011-04-12 |
The Rockefeller University |
Glycolipids and analogues thereof as antigens for NKT cells
|
DK1835937T3
(da)
|
2005-01-06 |
2012-07-23 |
Novo Nordisk As |
Sammensætninger og fremgangsmåder til behandling af virusinfektion
|
US7837990B2
(en)
|
2005-03-28 |
2010-11-23 |
The Rockefeller University |
In vivo expanded NKT cells and methods of use thereof
|
MX2007012197A
(es)
|
2005-03-31 |
2007-11-21 |
Biomedics Inc |
Anticuerpo monoclonal anti-cd20.
|
BRPI0610203A2
(pt)
|
2005-05-24 |
2010-06-01 |
Avestha Gengraine Tech Pvt Ltd |
processo de preparação in vivo de anti-corpo monoclonal anti-cd 20 biologicamente ativo e composição farmacêutica
|
AU2006252733A1
(en)
|
2005-06-02 |
2006-12-07 |
Astrazeneca Ab |
Antibodies directed to CD20 and uses thereof
|
PT1896071E
(pt)
*
|
2005-06-30 |
2015-07-09 |
Janssen Biotech Inc |
Métodos e composições com melhorias na atividade terapêutica
|
JP2007036104A
(ja)
|
2005-07-29 |
2007-02-08 |
Nec Electronics Corp |
半導体装置およびその製造方法
|
AU2006287224A1
(en)
*
|
2005-08-31 |
2007-03-08 |
Centocor, Inc. |
Host cell lines for production of antibody constant region with enhanced effector function
|
AU2006308847C1
(en)
|
2005-10-31 |
2012-05-10 |
Oncomed Pharmaceuticals, Inc. |
Compositions and methods for treating and diagnosing cancer
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
US7781203B2
(en)
|
2005-12-29 |
2010-08-24 |
Corning Incorporated |
Supports for assaying analytes and methods of making and using thereof
|
US20090060921A1
(en)
*
|
2006-01-17 |
2009-03-05 |
Biolex Therapeutics, Inc. |
Glycan-optimized anti-cd20 antibodies
|
WO2007133855A2
(en)
|
2006-03-27 |
2007-11-22 |
University Of Maryland Biotechnology Institute |
Glycoprotein synthesis and remodeling by enzymatic transglycosylation
|
EP2018564B1
(en)
|
2006-05-18 |
2010-05-12 |
Veterinärmedizinische Universität Wien |
Detection method for influenza viruses
|
EP2035034A4
(en)
|
2006-06-09 |
2009-11-18 |
Univ Maryland |
GLYCOSYLATION-CONTROLLED ANTIBODY THERAPY
|
JP5215298B2
(ja)
|
2006-07-12 |
2013-06-19 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グリコシル化された基質から切断される末端単糖の固相検出
|
JP2008025989A
(ja)
|
2006-07-15 |
2008-02-07 |
Keio Gijuku |
局在表面プラズモン共鳴法と質量分析法によるリガンドの分析方法及びそのためのセンサー素子
|
CA2660516A1
(en)
|
2006-08-18 |
2008-02-21 |
Oncotherapy Science, Inc. |
Treating or preventing cancers over-expressing reg4 or kiaa0101
|
AU2007325283B2
(en)
|
2006-11-27 |
2012-08-30 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods of use
|
US8765390B2
(en)
|
2006-12-08 |
2014-07-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Identification and isolation of squamous carcinoma stem cells
|
US9239329B2
(en)
|
2006-12-18 |
2016-01-19 |
Japan Science And Technology Agency |
Method of measuring interaction between biomaterial and sugar chain, method of evaluating biomaterial in sugar chain selectivity, method of screening biomaterial, method of patterning biomaterials, and kits for performing these methods
|
CA2712562A1
(en)
|
2007-01-18 |
2008-07-24 |
Glykos Finland Ltd |
Novel specific cell binders
|
EP2108043A4
(en)
|
2007-01-18 |
2010-04-21 |
Suomen Punainen Risti Veripalv |
NEW METHODS AND REAGENTS FOR THE PRODUCTION OF CELLS
|
EP2109668A4
(en)
|
2007-01-22 |
2011-10-05 |
Macrogenics West Inc |
HUMAN CANCER STEM CELLS
|
WO2008103824A1
(en)
|
2007-02-23 |
2008-08-28 |
Chinese Academy Of Inspection And Quarantine (Caiq) |
Sensitivity-enhanced dot-antibody linked immunogold assay for virus detection
|
US20080220988A1
(en)
|
2007-03-07 |
2008-09-11 |
Ada Technologies, Inc. |
Preparing carbohydrate microarrays and conjugated nanoparticles
|
SI2123271T1
(sl)
|
2007-03-07 |
2012-05-31 |
Daiichi Sankyo Co Ltd |
Zdravilo za zdravljenje influence
|
US7943330B2
(en)
|
2007-03-23 |
2011-05-17 |
Academia Sinica |
Tailored glycoproteomic methods for the sequencing, mapping and identification of cellular glycoproteins
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
EP2308514B1
(en)
|
2007-03-23 |
2013-06-05 |
to-BBB Holding B.V. |
Conjugates for targeted drug delivery across the blood-brain barrier
|
EP2144594A4
(en)
|
2007-04-13 |
2012-12-05 |
Academia Sinica |
ALPHA GALACTOSYL CERAMIDE ANALOGUES AND THEIR USE AS IMMUNOTHERAPY
|
US8153134B2
(en)
|
2007-04-23 |
2012-04-10 |
Schering Corporation |
Anti-MDL-1 antibodies
|
US8082480B2
(en)
|
2007-06-27 |
2011-12-20 |
Presagis |
Distributed checksum computation
|
AU2008275649B2
(en)
|
2007-07-12 |
2013-09-05 |
Sangamo Therapeutics, Inc. |
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT 8) gene expression
|
EP2022848A1
(en)
|
2007-08-10 |
2009-02-11 |
Hubrecht Institut |
A method for identifying, expanding, and removing adult stem cells and cancer stem cells
|
JP5345059B2
(ja)
|
2007-08-24 |
2013-11-20 |
Lsipファンド運営合同会社 |
婦人科癌の検出方法
|
WO2009029888A2
(en)
|
2007-08-31 |
2009-03-05 |
Chi-Huey Wong |
Synthesis of oseltamivir containing phosphonate congeners with anti-influenza activity
|
FR2921387B1
(fr)
|
2007-09-26 |
2012-04-20 |
Sanofi Pasteur |
Procede de production du virus de la grippe
|
US8647626B2
(en)
|
2007-10-02 |
2014-02-11 |
Avaxia Biologics, Incorporated |
Compositions comprising TNF-specific antibodies for oral delivery
|
US20090123439A1
(en)
|
2007-11-09 |
2009-05-14 |
The Jackson Laboratory |
Diagnostic and prognosis methods for cancer stem cells
|
JP5570998B2
(ja)
|
2007-12-31 |
2014-08-13 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
TNFαに対する抗体
|
BRPI0908968A8
(pt)
|
2008-03-21 |
2016-06-28 |
Danisco Us Inc |
composição enriquecidas com hemicelulase para potencializar a hidrólise de biomassa
|
JP5561700B2
(ja)
|
2008-03-25 |
2014-07-30 |
独立行政法人理化学研究所 |
新規糖脂質及びその用途
|
CN102016585B
(zh)
|
2008-04-09 |
2017-10-10 |
贝克顿·迪金森公司 |
使用包被的纳米颗粒的灵敏的免疫测定
|
US8383554B2
(en)
|
2008-04-14 |
2013-02-26 |
Academia Sinica |
Quantitative microarray of intact glycolipid CD1d interaction and correlation with cell-based cytokine production
|
AU2009240637A1
(en)
*
|
2008-04-22 |
2009-10-29 |
The Rockefeller University |
Methods of identifying anti-inflammatory compounds
|
US8906832B2
(en)
|
2008-04-30 |
2014-12-09 |
Academia Sinica |
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants
|
WO2009140853A1
(en)
|
2008-05-23 |
2009-11-26 |
The University Of Hong Kong |
Combination therapy for the treatment of influenza
|
US20110137570A1
(en)
*
|
2008-05-30 |
2011-06-09 |
Anthony Lapadula |
Methods for structural analysis of glycans
|
CN102065868A
(zh)
|
2008-06-16 |
2011-05-18 |
中央研究院 |
诱发对于Globo H及SSEA3的特异免疫反应的组合物以及其在癌症治疗中的用途
|
EP2307887B1
(en)
|
2008-06-16 |
2014-05-07 |
Academia Sinica |
Cancer diagnosis based on levels of antibodies against globo h and its fragments
|
JP2010014691A
(ja)
|
2008-06-20 |
2010-01-21 |
Igaku Seibutsugaku Kenkyusho:Kk |
腹水中のメソテリン及び/又は巨核球増強因子を検出するための方法、キット、試薬及び装置
|
US20100003674A1
(en)
|
2008-07-03 |
2010-01-07 |
Cope Frederick O |
Adult stem cells, molecular signatures, and applications in the evaluation, diagnosis, and therapy of mammalian conditions
|
US7928077B2
(en)
|
2008-07-11 |
2011-04-19 |
Academia Sinica |
Alpha-galactosyl ceramide analogs and their use as immunotherapies
|
EP2318832B1
(en)
|
2008-07-15 |
2013-10-09 |
Academia Sinica |
Glycan arrays on ptfe-like aluminum coated glass slides and related methods
|
US20100022916A1
(en)
|
2008-07-24 |
2010-01-28 |
Javanbakhsh Esfandiari |
Method and Apparatus for Collecting and Preparing Biological Samples for Testing
|
GB0816679D0
(en)
|
2008-09-11 |
2008-10-22 |
Univ Bath |
Compounds for treating viral infections
|
KR20110084196A
(ko)
|
2008-09-26 |
2011-07-21 |
유레카 쎄라퓨틱스, 인코포레이티드 |
다양한 글리코실화 패턴을 가진 세포계 및 단백질
|
ES2582208T3
(es)
|
2008-10-27 |
2016-09-09 |
Sapporo Medical University |
Marcador molecular para células madre cancerosas
|
BRPI0916042A2
(pt)
*
|
2008-11-17 |
2015-11-10 |
Hoffmann La Roche |
uso de uma formulação, formulação farmacêutica, usos de um anticorpo 2h7 humanizado, método de melhorar ou manter a solubilização, método para aumentar a biodisponibilidade de um anticorpo e método de diálise in vitro
|
CN102333872B
(zh)
*
|
2009-02-25 |
2014-07-09 |
默沙东公司 |
在糖工程化的酵母巴斯德毕赤酵母中对半乳糖同化途径的代谢工程化
|
EP2411528B1
(en)
|
2009-03-27 |
2015-09-02 |
Academia Sinica |
Alpha-selective sialyl phosphate donors for preparation of sialosides and sialoside arrays for influenza virus detection
|
JP2012526121A
(ja)
*
|
2009-05-04 |
2012-10-25 |
アボツト・バイオテクノロジー・リミテツド |
ヒト抗tnfアルファ抗体の安定した高蛋白質濃度製剤
|
WO2011005756A1
(en)
|
2009-07-06 |
2011-01-13 |
Puretech Ventures, Llc |
Delivery of agents targeted to microbiota niches
|
US8815941B2
(en)
|
2009-07-15 |
2014-08-26 |
The University Of British Columbia |
2,3-fluorinated glycosides as neuraminidase inhibitors and their use as anti-virals
|
EP2456464A4
(en)
|
2009-07-22 |
2013-02-20 |
Enzon Pharmaceuticals Inc |
METHODS OF TREATING POSITIVE HER2 CANCER WITH HER2 RECEPTOR ANTAGONIST IN COMBINATION WITH 7-ETHYL-10-HYDROXYCAMPTOTHECIN MULTI-ARM POLYMERIC CONJUGATES
|
US20120172329A1
(en)
|
2009-09-14 |
2012-07-05 |
Thailand Excellence Center For Tissue Engineering |
Phytochemical compositions including xanthones for anti-inflammatory, anti-cytokine storm, and other uses
|
US10087236B2
(en)
*
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
WO2011074621A1
(ja)
|
2009-12-18 |
2011-06-23 |
株式会社医学生物学研究所 |
メソセリン(msln)に対する抗体及びその用途
|
EP2347769A1
(en)
|
2010-01-20 |
2011-07-27 |
Glycotope GmbH |
Cancer stem cell markers and uses thereof
|
JP2013519682A
(ja)
|
2010-02-11 |
2013-05-30 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
抗cd200抗体を使用する治療方法
|
CN102858949B
(zh)
|
2010-02-24 |
2016-07-06 |
默沙东公司 |
用于增加在巴氏毕赤酵母中生产的治疗性糖蛋白上的n-糖基化位点占据的方法
|
SG10202001677QA
(en)
|
2010-03-12 |
2020-04-29 |
Debiopharm International S A |
Cd37-binding molecules and immunoconjugates thereof
|
US10338069B2
(en)
|
2010-04-12 |
2019-07-02 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
CA3122219A1
(en)
|
2010-04-16 |
2011-10-20 |
The Children's Hospital Corporation |
Sustained polypeptide expression from synthetic, modified rnas and uses thereof
|
WO2011143262A2
(en)
|
2010-05-10 |
2011-11-17 |
Sinica, Academia |
Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses
|
WO2011145957A1
(en)
|
2010-05-20 |
2011-11-24 |
Auckland Uniservices Limited |
Agents and methods for detection and/or imaging of hypoxia
|
KR101818274B1
(ko)
*
|
2010-05-27 |
2018-01-12 |
머크 샤프 앤드 돔 코포레이션 |
개선된 특성을 갖는 항체의 제조 방법
|
GB201015569D0
(en)
|
2010-09-16 |
2010-10-27 |
Medical Res Council |
Blood assay for prions
|
WO2012082635A1
(en)
|
2010-12-13 |
2012-06-21 |
Ancora Pharmaceuticals, Inc. |
Synthetic oligosaccharide group a streptococcus
|
CA2854725C
(en)
|
2011-01-05 |
2019-10-22 |
National Taiwan University |
Methods for preparation of glycosphingolipids and uses thereof
|
JP2014509323A
(ja)
|
2011-02-28 |
2014-04-17 |
マックマスター ユニヴァーシティ |
ドーパミン受容体遮断薬による癌の処置
|
US10851174B2
(en)
|
2011-03-03 |
2020-12-01 |
University Of Maryland, Baltimore |
Core fucosylated glycopeptides and glycoproteins: chemoenzymatic synthesis and uses thereof
|
CA2834589A1
(en)
|
2011-05-25 |
2012-11-29 |
Merck Sharp & Dohme Corp. |
Method for preparing fc-containing polypeptides having improved properties
|
ES2841899T3
(es)
|
2011-07-18 |
2021-07-12 |
Inst Res Biomedicine |
Anticuerpos neutralizantes del virus de la influenza A y usos de los mismos
|
JP5795067B2
(ja)
|
2011-07-21 |
2015-10-14 |
京セラ株式会社 |
照明装置、イメージセンサヘッドおよびこれを備える読取装置
|
KR102021159B1
(ko)
|
2011-08-12 |
2019-09-11 |
닛산 가가쿠 가부시키가이샤 |
트리시클릭 헤테로시클릭 화합물 및 jak 저해제
|
IN2014CN03072A
(zh)
*
|
2011-10-31 |
2015-07-31 |
Merck Sharp & Dohme |
|
WO2013074598A1
(en)
*
|
2011-11-18 |
2013-05-23 |
Merck Sharp & Dohme Corp. |
Fc CONTAINING POLYPEPTIDES HAVING INCREASED ANTI-INFLAMMATORY PROPERTIES AND INCREASED FcRN BINDING
|
EP2604281B1
(en)
|
2011-12-14 |
2014-07-30 |
Centre National de la Recherche Scientifique (CNRS) |
Clicked somatostatin conjugated analogs for biological applications
|
CN107954963A
(zh)
|
2012-01-19 |
2018-04-24 |
不列颠哥伦比亚大学 |
3’平伏氟取代的神经氨酸酶抑制剂化合物、组合物及其用作抗病毒剂的方法
|
GB201201314D0
(en)
|
2012-01-26 |
2012-03-07 |
Isis Innovation |
Composition
|
CN104220603B
(zh)
*
|
2012-02-10 |
2017-06-06 |
马里兰大学,巴尔的摩 |
抗体及其Fc片段的化学酶法糖基化工程
|
US9846160B2
(en)
|
2012-02-27 |
2017-12-19 |
Board Of Regents, The University Of Texas Systems |
Ganglioside GD2 as a marker and target on cancer stem cells
|
US20150231219A1
(en)
|
2012-04-02 |
2015-08-20 |
Merrimack Pharmaceuticals, Inc. |
Dosage and administration of monospecific and bispecific anti-igr-1r and anti-erbb3 antibodies
|
WO2013151649A1
(en)
|
2012-04-04 |
2013-10-10 |
Sialix Inc |
Glycan-interacting compounds
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
EP2855745A4
(en)
|
2012-06-01 |
2016-01-20 |
Momenta Pharmaceuticals Inc |
METHODS RELATING TO ADALIMUM AB
|
JP6302909B2
(ja)
|
2012-08-18 |
2018-03-28 |
アカデミア シニカAcademia Sinica |
シアリダーゼの同定および画像化のための細胞透過性プローブ
|
TWI573876B
(zh)
|
2012-08-20 |
2017-03-11 |
中央研究院 |
寡醣之大規模酵素合成
|
CA2883168A1
(en)
|
2012-08-21 |
2014-02-27 |
Academia Sinica |
Benzocyclooctyne compounds and uses thereof
|
EP4035685A1
(en)
|
2012-10-30 |
2022-08-03 |
Esperance Pharmaceuticals, Inc. |
Antibody/drug conjugates and methods of use
|
CA2890575C
(en)
*
|
2012-11-05 |
2021-11-09 |
Jumpei Enami |
Antibody and antibody composition production method
|
WO2014078373A1
(en)
|
2012-11-13 |
2014-05-22 |
Iogenetics, Llc |
Antimicrobial compositions
|
CN103045647A
(zh)
*
|
2012-11-29 |
2013-04-17 |
大连大学 |
核心岩藻糖基转移酶基因沉默细胞模型的建立及鉴定方法
|
GB201305986D0
(en)
|
2013-04-03 |
2013-05-15 |
Asociaci N Ct De Investigaci N Cooperativa En Biomateriales |
Synthesis and use of isotopically-labelled glycans
|
WO2014167126A2
(en)
|
2013-04-13 |
2014-10-16 |
Universidade De Coimbra |
Platform for targeted delivery to stem cells and tumor cells and methods thereof
|
CN104225616A
(zh)
|
2013-06-08 |
2014-12-24 |
中南大学 |
一种靶向卵巢癌干细胞的抗肿瘤生物制剂
|
WO2014210397A1
(en)
|
2013-06-26 |
2014-12-31 |
Academia Sinica |
Rm2 antigens and use thereof
|
WO2014210564A1
(en)
|
2013-06-27 |
2014-12-31 |
Academia Sinica |
Glycan conjugates and use thereof
|
TWI599370B
(zh)
|
2013-07-26 |
2017-09-21 |
中央研究院 |
靈芝多醣誘發之抗體介導抗腫瘤活性
|
US10202590B2
(en)
|
2013-09-05 |
2019-02-12 |
Vib Vzw |
Cells producing Fc-containing molecules having altered glycosylation patterns and methods and use thereof
|
KR102298172B1
(ko)
|
2013-09-06 |
2021-09-06 |
아카데미아 시니카 |
변화된 글리코실 그룹을 갖는 당지질을 사용한 인간 iNKT 세포 활성화
|
US20160201132A1
(en)
|
2013-09-12 |
2016-07-14 |
Teva Pharmaceutical Industries Ltd. |
Gene expression biomarkers of laquinimod responsiveness
|
CN103436627B
(zh)
|
2013-09-13 |
2016-02-03 |
四川大学华西医院 |
一种恶性乳腺癌干细胞的筛查试剂盒
|
WO2015054039A1
(en)
*
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Fc CONTAINING POLYPEPTIDES HAVING INCREASED BINDING TO FcGammaRIIB
|
WO2015109180A2
(en)
|
2014-01-16 |
2015-07-23 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
US10150818B2
(en)
*
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
TWI682033B
(zh)
*
|
2014-03-17 |
2020-01-11 |
泉盛生物科技股份有限公司 |
製造具有經修飾的糖苷化作用之重組糖蛋白之方法
|
CN106415244B
(zh)
|
2014-03-27 |
2020-04-24 |
中央研究院 |
反应性标记化合物及其用途
|
EP3149045B1
(en)
|
2014-05-27 |
2023-01-18 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
KR102512592B1
(ko)
|
2014-05-27 |
2023-03-21 |
아카데미아 시니카 |
항-her2 글리코항체 및 이의 용도
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
EP3149036A4
(en)
*
|
2014-05-27 |
2017-12-27 |
Academia Sinica |
Anti-cd20 glycoantibodies and uses thereof
|
CA2950433A1
(en)
|
2014-05-28 |
2015-12-03 |
Academia Sinica |
Anti-tnf-alpha glycoantibodies and uses thereof
|
US10273295B2
(en)
|
2014-08-19 |
2019-04-30 |
Miltenyi Biotec Gmbh |
Chimeric antigen receptor specific for SSEA4 antigen
|
WO2016029071A1
(en)
|
2014-08-22 |
2016-02-25 |
Academia Sinica |
Novel glycan conjugates and use thereof
|
US9879042B2
(en)
|
2014-09-08 |
2018-01-30 |
Academia Sinica |
Human iNKT cell activation using glycolipids
|
MX2017003246A
(es)
|
2014-09-12 |
2018-01-24 |
Univ California |
Macropinocitosis de anticuerpos anti-cd46 humanos y agentes terapeuticos dirigidos contra el cancer.
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
WO2016118090A1
(en)
|
2015-01-23 |
2016-07-28 |
Agency For Science, Technology And Research |
Cancer specific antigen-binding proteins
|
US10342858B2
(en)
|
2015-01-24 |
2019-07-09 |
Academia Sinica |
Glycan conjugates and methods of use thereof
|
DK3250590T3
(da)
*
|
2015-01-30 |
2021-10-18 |
Academia Sinica |
Sammensætninger og fremgangsmåder, der vedrører universelle glycoformer, til øget anti-SSEA4-antistofeffektivitet
|
US20170283878A1
(en)
|
2015-12-11 |
2017-10-05 |
Academia Sinica |
Modulation of globoseries glycosphingolipid synthesis and cancer biomarkers
|
CA3016170A1
(en)
|
2016-03-08 |
2017-09-14 |
Academia Sinica |
Methods for modular synthesis of n-glycans and arrays thereof
|
JP2019513144A
(ja)
|
2016-03-29 |
2019-05-23 |
オービーアイ ファーマ,インコーポレイテッド |
抗体、医薬組成物及び方法
|
CN109963868B
(zh)
|
2016-08-22 |
2023-11-14 |
醣基生医股份有限公司 |
抗体、结合片段及使用方法
|
AU2017315677B2
(en)
|
2016-08-24 |
2021-03-11 |
Academia Sinica |
Endoglycosidase mutants for glycoprotein remodeling and methods of using it
|
CA3044274A1
(en)
|
2016-11-21 |
2018-05-24 |
Obi Pharma, Inc. |
Conjugated biological molecules, pharmaceutical compositions and methods
|
TW202035444A
(zh)
|
2018-06-27 |
2020-10-01 |
台灣浩鼎生技股份有限公司 |
用於糖蛋白工程的糖苷合成酶變體及其使用方法
|