TR200101348T2 - Yeni tedavi metodu - Google Patents
Yeni tedavi metoduInfo
- Publication number
- TR200101348T2 TR200101348T2 TR2001/01348T TR200101348T TR200101348T2 TR 200101348 T2 TR200101348 T2 TR 200101348T2 TR 2001/01348 T TR2001/01348 T TR 2001/01348T TR 200101348 T TR200101348 T TR 200101348T TR 200101348 T2 TR200101348 T2 TR 200101348T2
- Authority
- TR
- Turkey
- Prior art keywords
- treatment method
- new treatment
- diabetes
- plasma concentration
- threshold
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Insülin sensitizörünün etkili plazma seviyeleri araliginda, en azindan esik degerinde bir plazma konsantrasyonunu (Esik Plazma Konsantrasyonu) saglamak üzere Bilesik (I) gibi bir insülin sensitizörünün toksik olmayan etkili bir miktarinin buna ihtiyaç duyan bir insana veya insan olmayan bir memeliye uygulanmasini kapsayan, Tip 2 sekerli diabetin ve sekerli diabet ile ilintili durumlarin tedavisi için bir metod, böyle bir metodda kullanilacak terkipler ve bu gibi metodlarda kullanilacak aktif maddenin plazma konsantrasyonlarinin tespit edilmesi için bir metodoloji.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9824893.3A GB9824893D0 (en) | 1998-11-12 | 1998-11-12 | Novel method of treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200101348T2 true TR200101348T2 (tr) | 2002-02-21 |
Family
ID=10842389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/01348T TR200101348T2 (tr) | 1998-11-12 | 1999-11-12 | Yeni tedavi metodu |
Country Status (40)
Country | Link |
---|---|
EP (2) | EP1135128B1 (tr) |
JP (1) | JP2003521455A (tr) |
KR (2) | KR20070048279A (tr) |
CN (3) | CN1235586C (tr) |
AP (2) | AP1580A (tr) |
AR (2) | AR029317A1 (tr) |
AT (1) | ATE366573T1 (tr) |
AU (1) | AU768303B2 (tr) |
BG (2) | BG65577B1 (tr) |
BR (1) | BR9915284A (tr) |
CA (1) | CA2350425C (tr) |
CO (1) | CO5150158A1 (tr) |
CY (1) | CY1106892T1 (tr) |
CZ (1) | CZ299801B6 (tr) |
DE (1) | DE69936533T2 (tr) |
DK (1) | DK1135128T3 (tr) |
DZ (1) | DZ2938A1 (tr) |
EA (2) | EA200700968A1 (tr) |
ES (1) | ES2289833T3 (tr) |
GB (1) | GB9824893D0 (tr) |
HK (1) | HK1041202B (tr) |
HR (1) | HRP20010344B1 (tr) |
HU (1) | HUP0104262A3 (tr) |
IL (1) | IL143088A0 (tr) |
MA (1) | MA26759A1 (tr) |
MY (1) | MY128347A (tr) |
NO (1) | NO328391B1 (tr) |
NZ (1) | NZ527132A (tr) |
OA (1) | OA12193A (tr) |
PE (1) | PE20001239A1 (tr) |
PL (1) | PL349421A1 (tr) |
PT (1) | PT1135128E (tr) |
RS (1) | RS50130B (tr) |
SK (1) | SK286357B6 (tr) |
TR (1) | TR200101348T2 (tr) |
TW (1) | TWI234456B (tr) |
UA (1) | UA79730C2 (tr) |
UY (2) | UY25797A1 (tr) |
WO (1) | WO2000027341A2 (tr) |
ZA (1) | ZA200103793B (tr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY125516A (en) | 1999-11-16 | 2006-08-30 | Smithkline Beecham Plc | Novel composition based on thiazolidinedione and metformin and use |
AU2002367154A1 (en) * | 2001-12-21 | 2003-07-15 | Smithkline Beecham Corporation | Dosing regimen for ppar-gamma activators |
WO2012074375A1 (en) * | 2010-12-01 | 2012-06-07 | N.V. Nutricia | Prevention or treatment of overweight and obesity in type 2 diabetic patients |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
JPS5697277A (en) * | 1980-01-07 | 1981-08-05 | Takeda Chem Ind Ltd | Thiazolidine derivative |
JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
US4582839A (en) * | 1984-03-21 | 1986-04-15 | Takeda Chemical Industries, Ltd. | 2,4-thiazolidinediones |
CN1003445B (zh) * | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物,其制备方法和用途 |
JPH06779B2 (ja) * | 1985-06-10 | 1994-01-05 | 武田薬品工業株式会社 | チアゾリジオン誘導体およびそれを含んでなる医薬組成物 |
US4812570A (en) * | 1986-07-24 | 1989-03-14 | Takeda Chemical Industries, Ltd. | Method for producing thiazolidinedione derivatives |
ES2137915T3 (es) * | 1987-09-04 | 2000-01-01 | Beecham Group Plc | Derivados de tiazolidindiona sustituida. |
US4791125A (en) * | 1987-12-02 | 1988-12-13 | Pfizer Inc. | Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents |
MX15171A (es) * | 1988-03-08 | 1993-05-01 | Pfizer | Derivados de tiazolidinodiona hipoglicemicos |
US5061717A (en) * | 1988-03-08 | 1991-10-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
GB8919417D0 (en) * | 1989-08-25 | 1989-10-11 | Beecham Group Plc | Novel compounds |
WO1991007107A1 (en) * | 1989-11-13 | 1991-05-30 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
JPH0469331A (ja) * | 1990-07-10 | 1992-03-04 | Asahi Chem Ind Co Ltd | 徐放性エマルジョン製剤 |
JP2572673B2 (ja) * | 1990-07-25 | 1997-01-16 | エスエス製薬株式会社 | 徐放性錠剤 |
JPH04210683A (ja) * | 1990-12-06 | 1992-07-31 | Terumo Corp | チアゾリジン−2,4−ジオン誘導体およびこれを含有する糖尿病合併症治療薬 |
US5183823A (en) * | 1991-04-11 | 1993-02-02 | Takeda Chemical Industries, Ltd. | Pyridine n-oxide compounds which are useful as hypoglycemic and hypolipidemic agents |
FR2680512B1 (fr) * | 1991-08-20 | 1995-01-20 | Adir | Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
DK0601001T3 (da) * | 1991-08-26 | 1997-10-20 | Upjohn Co | Flydende næringsmiddelprodukt indeholdende 3-guanidinopropionsyre. |
GB9218830D0 (en) * | 1992-09-05 | 1992-10-21 | Smithkline Beecham Plc | Novel compounds |
US5506245A (en) * | 1992-10-12 | 1996-04-09 | Adir Et Compagnie | Thiazolidinedione compounds |
US5478853A (en) * | 1992-10-12 | 1995-12-26 | Adir Et Compagnie | Thazolidinedione compounds |
CA2115587A1 (en) * | 1993-02-18 | 1994-08-19 | Hayato Kihara | Styrene copolymers, polystyrene compositions, processes for producing styrene copolymers, and injection-molded articles |
DE4317320A1 (de) * | 1993-05-25 | 1994-12-01 | Boehringer Mannheim Gmbh | Neue Thiazolidindione und diese enthaltende Arzneimittel |
US5457109A (en) * | 1993-09-15 | 1995-10-10 | Warner-Lambert Company | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
ATE376829T1 (de) * | 1993-09-15 | 2007-11-15 | Daiichi Sankyo Co Ltd | Verwendung von thiazolidindionen zur vorbeugung oder verzögerung des auftretens des nichtinsulinabhängigen diabetes mellitus (niddm) |
US5902726A (en) * | 1994-12-23 | 1999-05-11 | Glaxo Wellcome Inc. | Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma |
US5708012A (en) * | 1995-04-28 | 1998-01-13 | Sankyo Company, Limited | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of insulin resistant subjects with normal glucose tolerance in order to prevent or delay the onset of noninsulin-dependent mellitus |
US5859037A (en) * | 1997-02-19 | 1999-01-12 | Warner-Lambert Company | Sulfonylurea-glitazone combinations for diabetes |
US6011049A (en) * | 1997-02-19 | 2000-01-04 | Warner-Lambert Company | Combinations for diabetes |
-
1998
- 1998-11-12 GB GBGB9824893.3A patent/GB9824893D0/en not_active Ceased
-
1999
- 1999-11-10 AR ARP990105701A patent/AR029317A1/es unknown
- 1999-11-10 DZ DZ990238A patent/DZ2938A1/xx active
- 1999-11-10 AR ARP990105700A patent/AR029149A1/es unknown
- 1999-11-11 MY MYPI99004899A patent/MY128347A/en unknown
- 1999-11-12 DE DE69936533T patent/DE69936533T2/de not_active Expired - Lifetime
- 1999-11-12 HU HU0104262A patent/HUP0104262A3/hu unknown
- 1999-11-12 OA OA00100118A patent/OA12193A/en unknown
- 1999-11-12 AT AT99960293T patent/ATE366573T1/de active
- 1999-11-12 RS YUP-374/01A patent/RS50130B/sr unknown
- 1999-11-12 EA EA200700968A patent/EA200700968A1/ru unknown
- 1999-11-12 CA CA002350425A patent/CA2350425C/en not_active Expired - Fee Related
- 1999-11-12 KR KR1020077009372A patent/KR20070048279A/ko not_active Application Discontinuation
- 1999-11-12 ES ES99960293T patent/ES2289833T3/es not_active Expired - Lifetime
- 1999-11-12 IL IL14308899A patent/IL143088A0/xx unknown
- 1999-11-12 PT PT99960293T patent/PT1135128E/pt unknown
- 1999-11-12 UA UA2001053164A patent/UA79730C2/uk unknown
- 1999-11-12 EA EA200100539A patent/EA009192B1/ru not_active IP Right Cessation
- 1999-11-12 NZ NZ527132A patent/NZ527132A/en not_active IP Right Cessation
- 1999-11-12 KR KR1020017006028A patent/KR20010080440A/ko not_active Application Discontinuation
- 1999-11-12 CN CNB998154806A patent/CN1235586C/zh not_active Expired - Fee Related
- 1999-11-12 AP APAP/P/2001/002137A patent/AP1580A/en active
- 1999-11-12 CO CO99071567A patent/CO5150158A1/es unknown
- 1999-11-12 BR BR9915284-3A patent/BR9915284A/pt not_active Application Discontinuation
- 1999-11-12 WO PCT/US1999/026746 patent/WO2000027341A2/en active IP Right Grant
- 1999-11-12 CZ CZ20011656A patent/CZ299801B6/cs not_active IP Right Cessation
- 1999-11-12 SK SK642-2001A patent/SK286357B6/sk not_active IP Right Cessation
- 1999-11-12 JP JP2000580572A patent/JP2003521455A/ja active Pending
- 1999-11-12 EP EP99960293A patent/EP1135128B1/en not_active Expired - Lifetime
- 1999-11-12 CN CNA2008100058350A patent/CN101244062A/zh active Pending
- 1999-11-12 UY UY25797A patent/UY25797A1/es not_active Application Discontinuation
- 1999-11-12 DK DK99960293T patent/DK1135128T3/da active
- 1999-11-12 PL PL99349421A patent/PL349421A1/xx not_active Application Discontinuation
- 1999-11-12 EP EP06124048A patent/EP1759698A1/en not_active Withdrawn
- 1999-11-12 AU AU17196/00A patent/AU768303B2/en not_active Ceased
- 1999-11-12 AP AP2005003432A patent/AP2005003432A0/xx unknown
- 1999-11-12 TR TR2001/01348T patent/TR200101348T2/tr unknown
- 1999-11-12 PE PE1999001148A patent/PE20001239A1/es not_active Application Discontinuation
- 1999-11-12 CN CNA2005101201583A patent/CN1771943A/zh active Pending
- 1999-11-15 UY UY25801A patent/UY25801A1/es not_active Application Discontinuation
- 1999-12-24 TW TW088122851A patent/TWI234456B/zh not_active IP Right Cessation
-
2001
- 2001-05-10 NO NO20012301A patent/NO328391B1/no not_active IP Right Cessation
- 2001-05-10 ZA ZA200103793A patent/ZA200103793B/en unknown
- 2001-05-11 HR HR20010344A patent/HRP20010344B1/xx not_active IP Right Cessation
- 2001-05-11 MA MA26193A patent/MA26759A1/fr unknown
- 2001-06-07 BG BG105569A patent/BG65577B1/bg unknown
- 2001-06-07 BG BG110061A patent/BG110061A/bg unknown
-
2002
- 2002-02-11 HK HK02101081.6A patent/HK1041202B/zh not_active IP Right Cessation
-
2007
- 2007-09-27 CY CY20071101240T patent/CY1106892T1/el unknown
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