SMT201300080B - Derivati di carbammati di alchiltiazoli, loro preparazione e loro utilizzo come inibitori dell'enzima faah - Google Patents

Derivati di carbammati di alchiltiazoli, loro preparazione e loro utilizzo come inibitori dell'enzima faah

Info

Publication number: SMT201300080B
Authority: SM; San Marino
Prior art keywords: alkiltiazole; inhibitors; preparation; carbamate derivatives; faah enzyme
Prior art date: 2008-07-23

Application number

SM201300080T

Other languages

English (en)

Italian (it)

Inventor

Ahmed Abouabdellah

Jochen Gorlitzer

Peter Hamley

Antoine Ravet

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-23

Filing date

2013-07-15

Publication date

2013-09-06

2013-07-15 Application filed by Sanofi Sa filed Critical Sanofi Sa

2013-09-06 Publication of SMT201300080B publication Critical patent/SMT201300080B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

SM201300080T 2008-07-23 2013-07-15 Derivati di carbammati di alchiltiazoli, loro preparazione e loro utilizzo come inibitori dell'enzima faah SMT201300080B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0804179A FR2934265B1 (fr)	2008-07-23	2008-07-23	Derives de carbamates d'alkylthiazoles, leur preparation et leur application en therapeutique
PCT/FR2009/051457 WO2010010288A2 (fr)	2008-07-23	2009-07-21	Derives de carbamates d'alkylthiazoles, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
SMT201300080B true SMT201300080B (it)	2013-09-06

Family

ID=40289184

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SM201300080T SMT201300080B (it)	2008-07-23	2013-07-15	Derivati di carbammati di alchiltiazoli, loro preparazione e loro utilizzo come inibitori dell'enzima faah

Country Status (28)

Country	Link
US (1)	US8912218B2 (pt)
EP (1)	EP2344486B1 (pt)
JP (1)	JP5452594B2 (pt)
KR (1)	KR20110034020A (pt)
CN (1)	CN102164920B (pt)
AR (1)	AR072593A1 (pt)
AU (1)	AU2009274355B2 (pt)
BR (1)	BRPI0916385A2 (pt)
CA (1)	CA2731789C (pt)
CL (1)	CL2011000147A1 (pt)
CO (1)	CO6351789A2 (pt)
CY (1)	CY1114519T1 (pt)
DK (1)	DK2344486T3 (pt)
EA (1)	EA018995B1 (pt)
ES (1)	ES2413304T3 (pt)
FR (1)	FR2934265B1 (pt)
HR (1)	HRP20130585T1 (pt)
IL (1)	IL210747A0 (pt)
MA (1)	MA32579B1 (pt)
MX (1)	MX2011000882A (pt)
PE (1)	PE20110384A1 (pt)
PL (1)	PL2344486T3 (pt)
PT (1)	PT2344486E (pt)
SI (1)	SI2344486T1 (pt)
SM (1)	SMT201300080B (pt)
TW (1)	TW201008937A (pt)
UY (1)	UY32004A (pt)
WO (1)	WO2010010288A2 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2938537B1 (fr) *	2008-11-14	2012-10-26	Sanofi Aventis	Derives de carbamates d'alkyl-heterocycles, leur preparation et leur application en therapeutique.
FR2941696B1 (fr) *	2009-02-05	2011-04-15	Sanofi Aventis	Derives d'azaspiranyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
FR2945534B1 (fr) *	2009-05-12	2012-11-16	Sanofi Aventis	DERIVES DE CYCLOPENTAL[c]PYRROLE-2-CARBOXYLATES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2945533B1 (fr) *	2009-05-12	2011-05-27	Sanofi Aventis	Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
WO2011085216A2 (en)	2010-01-08	2011-07-14	Ironwood Pharmaceuticals, Inc.	Use of faah inhibitors for treating parkinson's disease and restless legs syndrome
US20130224151A1 (en)	2010-03-31	2013-08-29	United States Of America	Use of FAAH Inhibitors for Treating Abdominal, Visceral and Pelvic Pain
CN103209695A (zh)	2010-09-15	2013-07-17	弗·哈夫曼-拉罗切有限公司	氮杂苯并噻唑化合物、组合物及应用方法
DE102012018115A1 (de)	2012-09-13	2014-03-13	Matthias Lehr	Aryl-N-(arylalkyl)carbamate als Hemmstoffe der Fatty Acid Amide Hydrolase
DE102013016573A1 (de)	2013-10-04	2015-04-09	Matthias Lehr	1-Tetrazolylpropan-2-one als Inhibitoren von cytosolischer Phospholipase A2 und Fatty Acid Amide Hydrolase, insbesondere geeignet zur topischen Anwendung
WO2020048831A1 (en)	2018-09-03	2020-03-12	Bayer Aktiengesellschaft	5-aryl-3,9-diazaspiro[5.5]undecan-2-one compounds
WO2020048830A1 (en)	2018-09-03	2020-03-12	Bayer Aktiengesellschaft	5-aryl-3,9-diazaspiro[5.5]undecan-2-one compounds
WO2020048828A1 (en)	2018-09-03	2020-03-12	Bayer Pharma Aktiengesellschaft	5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2854633B1 (fr) *	2003-05-07	2005-06-24	Sanofi Synthelabo	Derives de piperidinyl-et piperazinyl-alkylcarbamates, leur preparation et leur application en therapeutique
GB0417801D0 (en) *	2004-08-10	2004-09-15	Novartis Ag	Organic compounds
BRPI0515015A (pt) *	2004-08-11	2008-07-01	Kyorin Seiyaku Kk	derivado cìclico de ácido aminobenzóico; medicamento; agonista ppar(alpha); agonista duplo ppar(alpha), y; agonista duplo ppar(alpha), (delta); modulador ppar; agente lipìdeo; agente profilático ou terapêutico compreendendo pelo menos um dos derivados cìclicos de ácido aminobenzóico ou sal do mesmo farmacêuticamente aceitável
CL2008001933A1 (es) *	2007-06-29	2009-09-25	Millennium Pharm Inc	Compuestos derivados de pirimidina, inhibidores de la raf quinasa; compuestos intermediarios; procedimiento de preparacion; composicion farmaceutica; y su uso para tratar trastornos proliferativos, cardiacos, neurodegenerativos, inflamatorios, oseos, inmunologicos enfermedad viral, entre otros.
FR2938537B1 (fr) *	2008-11-14	2012-10-26	Sanofi Aventis	Derives de carbamates d'alkyl-heterocycles, leur preparation et leur application en therapeutique.

2008
- 2008-07-23 FR FR0804179A patent/FR2934265B1/fr not_active Expired - Fee Related
2009
- 2009-07-21 EP EP09737098A patent/EP2344486B1/fr active Active
- 2009-07-21 PL PL09737098T patent/PL2344486T3/pl unknown
- 2009-07-21 EA EA201170237A patent/EA018995B1/ru not_active IP Right Cessation
- 2009-07-21 WO PCT/FR2009/051457 patent/WO2010010288A2/fr active Application Filing
- 2009-07-21 US US13/003,713 patent/US8912218B2/en not_active Expired - Fee Related
- 2009-07-21 CA CA2731789A patent/CA2731789C/fr not_active Expired - Fee Related
- 2009-07-21 DK DK09737098.5T patent/DK2344486T3/da active
- 2009-07-21 AU AU2009274355A patent/AU2009274355B2/en not_active Ceased
- 2009-07-21 JP JP2011519216A patent/JP5452594B2/ja not_active Expired - Fee Related
- 2009-07-21 SI SI200930624T patent/SI2344486T1/sl unknown
- 2009-07-21 BR BRPI0916385-9A patent/BRPI0916385A2/pt not_active IP Right Cessation
- 2009-07-21 PE PE2011000070A patent/PE20110384A1/es not_active Application Discontinuation
- 2009-07-21 PT PT97370985T patent/PT2344486E/pt unknown
- 2009-07-21 KR KR1020117004019A patent/KR20110034020A/ko not_active Application Discontinuation
- 2009-07-21 ES ES09737098T patent/ES2413304T3/es active Active
- 2009-07-21 CN CN2009801372742A patent/CN102164920B/zh not_active Expired - Fee Related
- 2009-07-21 MX MX2011000882A patent/MX2011000882A/es active IP Right Grant
- 2009-07-22 AR ARP090102787A patent/AR072593A1/es not_active Application Discontinuation
- 2009-07-22 TW TW098124759A patent/TW201008937A/zh unknown
- 2009-07-23 UY UY0001032004A patent/UY32004A/es not_active Application Discontinuation
2011
- 2011-01-19 IL IL210747A patent/IL210747A0/en unknown
- 2011-01-20 CO CO11005623A patent/CO6351789A2/es not_active Application Discontinuation
- 2011-01-21 CL CL2011000147A patent/CL2011000147A1/es unknown
- 2011-02-22 MA MA33636A patent/MA32579B1/fr unknown
2013
- 2013-06-26 HR HRP20130585AT patent/HRP20130585T1/hr unknown
- 2013-06-27 CY CY20131100519T patent/CY1114519T1/el unknown
- 2013-07-15 SM SM201300080T patent/SMT201300080B/xx unknown

Also Published As

Publication number	Publication date
PT2344486E (pt)	2013-06-27
WO2010010288A3 (fr)	2010-03-18
AR072593A1 (es)	2010-09-08
EP2344486B1 (fr)	2013-03-27
FR2934265A1 (fr)	2010-01-29
BRPI0916385A2 (pt)	2018-06-05
AU2009274355B2 (en)	2014-01-30
IL210747A0 (en)	2011-03-31
UY32004A (es)	2010-02-26
CO6351789A2 (es)	2011-12-20
DK2344486T3 (da)	2013-07-08
CY1114519T1 (el)	2016-10-05
FR2934265B1 (fr)	2010-07-30
US8912218B2 (en)	2014-12-16
CA2731789C (fr)	2016-08-30
EP2344486A2 (fr)	2011-07-20
EA201170237A1 (ru)	2011-10-31
WO2010010288A2 (fr)	2010-01-28
HRP20130585T1 (en)	2013-07-31
ES2413304T3 (es)	2013-07-16
PE20110384A1 (es)	2011-07-01
PL2344486T3 (pl)	2013-08-30
CL2011000147A1 (es)	2011-06-17
JP5452594B2 (ja)	2014-03-26
AU2009274355A1 (en)	2010-01-28
US20110212963A1 (en)	2011-09-01
CN102164920B (zh)	2013-12-25
JP2011528704A (ja)	2011-11-24
CA2731789A1 (fr)	2010-01-28
CN102164920A (zh)	2011-08-24
TW201008937A (en)	2010-03-01
KR20110034020A (ko)	2011-04-04
EA018995B1 (ru)	2013-12-30
MX2011000882A (es)	2011-03-01
MA32579B1 (fr)	2011-08-01
SI2344486T1 (sl)	2013-07-31

Publication	Publication Date	Title
SMT201300080B (it)	2013-09-06	Derivati di carbammati di alchiltiazoli, loro preparazione e loro utilizzo come inibitori dell'enzima faah
SMT201400114B (it)	2014-11-10	Derivati di 2-arilimidazolo come inibitori dell'enzima pde10a
SMT201500213B (it)	2015-10-30	Alcune triazolopirazine, loro composizioni e metodi d'uso
SMT201400009B (it)	2014-03-07	Derivati eteroaromatici di ariltriazolo come inibitori dell'enzima pde 10A
BRPI0911688A2 (pt)	2015-07-28	"compostos de pirimidina, composições e métodos de uso"
SMT201400158B (it)	2015-01-15	Derivati eteroaromatici di fenilimidazolo come inibitori dell'enzima pde10a
IL222698A0 (en)	2012-12-31	Benzazole derivatives, compositions, and methods of use as b- secretase inhibitors
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