SI2182983T1 - Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta - Google Patents

Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta

Info

Publication number
SI2182983T1
SI2182983T1 SI200731495T SI200731495T SI2182983T1 SI 2182983 T1 SI2182983 T1 SI 2182983T1 SI 200731495 T SI200731495 T SI 200731495T SI 200731495 T SI200731495 T SI 200731495T SI 2182983 T1 SI2182983 T1 SI 2182983T1
Authority
SI
Slovenia
Prior art keywords
treatment
humanised anti
amyloidogenic diseases
abeta antibodies
abeta
Prior art date
Application number
SI200731495T
Other languages
English (en)
Inventor
Ivan Lieberburg
Jim Callaway
Michael Grundman
Original Assignee
Janssen Alzheimer Immunotherapy
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Alzheimer Immunotherapy, Wyeth Llc filed Critical Janssen Alzheimer Immunotherapy
Publication of SI2182983T1 publication Critical patent/SI2182983T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
SI200731495T 2007-07-27 2007-07-27 Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta SI2182983T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07755675.1A EP2182983B1 (en) 2007-07-27 2007-07-27 Treatment of amyloidogenic diseases with humanised anti-abeta antibodies
PCT/US2007/009499 WO2009017467A1 (en) 2007-07-27 2007-07-27 Treatment of amyloidogenic diseases

Publications (1)

Publication Number Publication Date
SI2182983T1 true SI2182983T1 (sl) 2014-09-30

Family

ID=40304570

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200731495T SI2182983T1 (sl) 2007-07-27 2007-07-27 Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta

Country Status (9)

Country Link
US (1) US8613920B2 (sl)
EP (1) EP2182983B1 (sl)
JP (1) JP5889529B2 (sl)
DK (1) DK2182983T3 (sl)
ES (1) ES2498040T3 (sl)
PL (1) PL2182983T3 (sl)
PT (1) PT2182983E (sl)
SI (1) SI2182983T1 (sl)
WO (1) WO2009017467A1 (sl)

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US8613920B2 (en) 2013-12-24
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JP5889529B2 (ja) 2016-03-22
EP2182983B1 (en) 2014-05-21
US20100221187A1 (en) 2010-09-02
PT2182983E (pt) 2014-09-01
DK2182983T3 (da) 2014-07-14
WO2009017467A1 (en) 2009-02-05
EP2182983A4 (en) 2011-03-02
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