SI1981872T1 - Sol jantarne kisline 1-(2-(2-kloro-4-(((R)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrokinolin -5-il)etilamino)metil)-5-metoksifenilkarbamoil)etil)piperidin-4-il estra bifenil-2-ilkarbamske kisline in njena uporaba za zdravljenje pljučnih motenj - Google Patents

Sol jantarne kisline 1-(2-(2-kloro-4-(((R)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrokinolin -5-il)etilamino)metil)-5-metoksifenilkarbamoil)etil)piperidin-4-il estra bifenil-2-ilkarbamske kisline in njena uporaba za zdravljenje pljučnih motenj

Info

Publication number
SI1981872T1
SI1981872T1 SI200731963T SI200731963T SI1981872T1 SI 1981872 T1 SI1981872 T1 SI 1981872T1 SI 200731963 T SI200731963 T SI 200731963T SI 200731963 T SI200731963 T SI 200731963T SI 1981872 T1 SI1981872 T1 SI 1981872T1
Authority
SI
Slovenia
Prior art keywords
hydroxy
ylaminoimethyl
methoxyphenylcarbamoyl
dihydroquinolin
eth
Prior art date
Application number
SI200731963T
Other languages
English (en)
Inventor
Reshma Chudasama
Andrew Kennedy
Leanda Jane Kindon
Franck Patrick Mallet
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36119909&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1981872(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of SI1981872T1 publication Critical patent/SI1981872T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
SI200731963T 2006-02-10 2007-02-08 Sol jantarne kisline 1-(2-(2-kloro-4-(((R)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrokinolin -5-il)etilamino)metil)-5-metoksifenilkarbamoil)etil)piperidin-4-il estra bifenil-2-ilkarbamske kisline in njena uporaba za zdravljenje pljučnih motenj SI1981872T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0602778.3A GB0602778D0 (en) 2006-02-10 2006-02-10 Novel compound
EP07704449.3A EP1981872B1 (en) 2006-02-10 2007-02-08 Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[ (r)-2-hydroxy-2- (8-hydroxy-2-oxo-1, 2-dihydroquinolin-5-yl) eth ylaminoimethyl]} -5-methoxyphenylcarbamoyl) ethyl]piperidin-4-yl ester and its use for the treatment of pulmonary disorders
PCT/EP2007/051196 WO2007090859A1 (en) 2006-02-10 2007-02-08 Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{ [ (r)-2-hydroxy-2- (8-hydroxy-2-oxo-1, 2-dihydroquinolin-5-yl) eth ylaminoimethyl] } -5-methoxyphenylcarbamoyl) ethyl] piperidin-4-yl ester and its use for the treatment of pulmonary disorders

Publications (1)

Publication Number Publication Date
SI1981872T1 true SI1981872T1 (sl) 2017-10-30

Family

ID=36119909

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200731963T SI1981872T1 (sl) 2006-02-10 2007-02-08 Sol jantarne kisline 1-(2-(2-kloro-4-(((R)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrokinolin -5-il)etilamino)metil)-5-metoksifenilkarbamoil)etil)piperidin-4-il estra bifenil-2-ilkarbamske kisline in njena uporaba za zdravljenje pljučnih motenj

Country Status (33)

Country Link
US (1) US7960551B2 (sl)
EP (1) EP1981872B1 (sl)
JP (1) JP5616021B2 (sl)
KR (1) KR101488691B1 (sl)
CN (1) CN101379057B (sl)
AR (2) AR059409A1 (sl)
AU (1) AU2007213767B2 (sl)
BR (1) BRPI0707559B8 (sl)
CA (1) CA2641769C (sl)
CR (1) CR10227A (sl)
CY (1) CY1119238T1 (sl)
DK (1) DK1981872T3 (sl)
EA (1) EA016580B1 (sl)
ES (1) ES2640226T3 (sl)
GB (1) GB0602778D0 (sl)
HR (1) HRP20171304T1 (sl)
HU (1) HUE034315T2 (sl)
IL (1) IL193103A (sl)
JO (1) JO3389B1 (sl)
LT (1) LT1981872T (sl)
MA (1) MA30273B1 (sl)
MY (1) MY153656A (sl)
NO (1) NO341343B1 (sl)
NZ (1) NZ570242A (sl)
PE (2) PE20110120A1 (sl)
PL (1) PL1981872T3 (sl)
PT (1) PT1981872T (sl)
SG (1) SG169404A1 (sl)
SI (1) SI1981872T1 (sl)
TW (1) TWI401251B (sl)
UA (1) UA100364C2 (sl)
WO (1) WO2007090859A1 (sl)
ZA (1) ZA200806782B (sl)

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TWI643853B (zh) 2013-02-27 2018-12-11 阿爾米雷爾有限公司 同時具有β2腎上腺素受體促效劑和M3毒蕈鹼受體拮抗劑活性之2-氨基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽類
TW201517906A (zh) 2013-07-25 2015-05-16 Almirall Sa 含有ｍａｂａ化合物和皮質類固醇之組合
TWI641373B (zh) 2013-07-25 2018-11-21 阿爾米雷爾有限公司 具有蕈毒鹼受體拮抗劑和β２腎上腺素受體促效劑二者之活性的２－胺基－１－羥乙基－８－羥基喹啉－２（１Ｈ）－酮衍生物之鹽
TW201617343A (zh) 2014-09-26 2016-05-16 阿爾米雷爾有限公司 具有β２腎上腺素促效劑及Ｍ３蕈毒拮抗劑活性之新穎雙環衍生物
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CN106632257B (zh) * 2016-12-15 2019-02-12 上海市奉贤区中心医院 Gsk961081及其中间体的合成方法
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Also Published As

Publication number Publication date
GB0602778D0 (en) 2006-03-22
LT1981872T (lt) 2017-09-11
HUE034315T2 (en) 2018-02-28
CN101379057B (zh) 2013-02-13
PT1981872T (pt) 2017-09-13
CA2641769C (en) 2014-02-04
UA100364C2 (xx) 2012-12-25
SG169404A1 (en) 2011-03-30
EA200801691A1 (ru) 2009-02-27
CA2641769A1 (en) 2007-08-16
IL193103A0 (en) 2009-02-11
PL1981872T3 (pl) 2017-11-30
US20070281971A1 (en) 2007-12-06
CR10227A (es) 2008-10-29
ES2640226T3 (es) 2017-11-02
NZ570242A (en) 2011-09-30
JO3389B1 (ar) 2019-03-13
ZA200806782B (en) 2009-10-28
BRPI0707559A2 (pt) 2011-05-10
NO20083425L (no) 2008-09-09
MA30273B1 (fr) 2009-03-02
BRPI0707559B1 (pt) 2021-01-12
TWI401251B (zh) 2013-07-11
JP2009526018A (ja) 2009-07-16
EA016580B1 (ru) 2012-06-29
CN101379057A (zh) 2009-03-04
AR059409A1 (es) 2008-04-09
EP1981872A1 (en) 2008-10-22
IL193103A (en) 2013-06-27
US7960551B2 (en) 2011-06-14
KR101488691B1 (ko) 2015-02-02
MY153656A (en) 2015-03-13
AU2007213767B2 (en) 2012-04-26
TW200800948A (en) 2008-01-01
KR20080114723A (ko) 2008-12-31
PE20110120A1 (es) 2011-03-08
PE20071249A1 (es) 2008-01-16
HRP20171304T1 (hr) 2017-10-20
CY1119238T1 (el) 2018-02-14
NO341343B1 (no) 2017-10-16
DK1981872T3 (en) 2017-09-11
AU2007213767A1 (en) 2007-08-16
WO2007090859A1 (en) 2007-08-16
JP5616021B2 (ja) 2014-10-29
BRPI0707559B8 (pt) 2021-05-25
AR104288A2 (es) 2017-07-12
EP1981872B1 (en) 2017-06-21
BRPI0707559A8 (pt) 2019-01-29

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