SI1824479T1 - Derivati fenilpiperazina s kombinacijo delnega dopamin-d2 receptorskega agonizma in inhibiranje ponovnega privzema serotonina - Google Patents
Derivati fenilpiperazina s kombinacijo delnega dopamin-d2 receptorskega agonizma in inhibiranje ponovnega privzema serotoninaInfo
- Publication number
- SI1824479T1 SI1824479T1 SI200530566T SI200530566T SI1824479T1 SI 1824479 T1 SI1824479 T1 SI 1824479T1 SI 200530566 T SI200530566 T SI 200530566T SI 200530566 T SI200530566 T SI 200530566T SI 1824479 T1 SI1824479 T1 SI 1824479T1
- Authority
- SI
- Slovenia
- Prior art keywords
- serotonin reuptake
- combination
- reuptake inhibition
- phenylpiperazine derivatives
- receptor agonism
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63407404P | 2004-12-08 | 2004-12-08 | |
EP04106394 | 2004-12-08 | ||
EP05816322A EP1824479B1 (en) | 2004-12-08 | 2005-12-06 | Phenylpiperazine derivatives with a combination of partial dopamine-d2 receptor agonism and serotonin reuptake inhibition |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1824479T1 true SI1824479T1 (sl) | 2009-04-30 |
Family
ID=35744728
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200530566T SI1824479T1 (sl) | 2004-12-08 | 2005-12-06 | Derivati fenilpiperazina s kombinacijo delnega dopamin-d2 receptorskega agonizma in inhibiranje ponovnega privzema serotonina |
SI200530416T SI1827427T1 (sl) | 2004-12-08 | 2005-12-06 | Derivati ariloksietilamina s kombinacijo agonizmadopaminskih d2 receptorjev in ponovnega privzema serotonina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200530416T SI1827427T1 (sl) | 2004-12-08 | 2005-12-06 | Derivati ariloksietilamina s kombinacijo agonizmadopaminskih d2 receptorjev in ponovnega privzema serotonina |
Country Status (18)
Country | Link |
---|---|
EP (4) | EP1824480A1 (sl) |
JP (4) | JP2008523030A (sl) |
KR (4) | KR20070085959A (sl) |
AT (2) | ATE413173T1 (sl) |
AU (4) | AU2005313311A1 (sl) |
BR (1) | BRPI0518613A2 (sl) |
CA (4) | CA2587202A1 (sl) |
DE (2) | DE602005008471D1 (sl) |
DK (2) | DK1827427T3 (sl) |
ES (2) | ES2311245T3 (sl) |
HR (2) | HRP20080538T3 (sl) |
IL (4) | IL183063A0 (sl) |
NO (4) | NO20072969L (sl) |
PL (2) | PL1827427T3 (sl) |
PT (2) | PT1824479E (sl) |
RU (4) | RU2007125659A (sl) |
SI (2) | SI1824479T1 (sl) |
WO (4) | WO2006061378A1 (sl) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007085651A1 (en) * | 2006-01-30 | 2007-08-02 | Speedel Experimenta Ag | Process for the stereoselective preparation of alcohols from alpha, beta- insaturated compounds |
US8063062B2 (en) | 2006-12-20 | 2011-11-22 | Solvay Pharmaceuticals B.V. | Compounds with a combination of cannabinoid-CB1 antagonism and acetylcholinesterase inhibition |
US8138174B2 (en) | 2007-01-10 | 2012-03-20 | Solvay Pharmaceuticals B.V. | Compounds with a combination of cannabinoid CB1 antagonism and serotonin reuptake inhibition |
CA2671554A1 (en) * | 2007-01-10 | 2008-07-17 | Solvay Pharmaceuticals B.V. | Compounds with a combination of cannabinoid-cb1 antagonism and serotonin reuptake inhibition |
RU2480462C2 (ru) * | 2007-04-23 | 2013-04-27 | Янссен Фармацевтика Н.В. | Производные пиридина, используемые в качестве быстро диссоциирующихся антагонистов допаминовых рецепторов 2 |
PT2148873E (pt) * | 2007-04-23 | 2012-11-20 | Janssen Pharmaceutica Nv | Derivados da 4-alcoxipiridazina antagonistas de dissociação rápida do recetor da dopamina 2 |
MX2009011416A (es) * | 2007-04-23 | 2009-11-05 | Janssen Pharmaceutica Nv | Tia(di)azoles como antagonistas del receptor de dopamina 2 de disociacion rapida. |
CN103360342B (zh) * | 2012-04-09 | 2015-12-16 | 江苏恩华药业股份有限公司 | 3-氰基苯胺烷基芳基哌嗪衍生物及在制备药物中的应用 |
CN103570698B (zh) * | 2012-08-01 | 2016-08-03 | 江苏恩华药业股份有限公司 | 用于制备维拉佐酮的化合物及其中间体和应用 |
ITMI20130392A1 (it) * | 2013-03-15 | 2014-09-16 | Dipharma Francis Srl | Sintesi di un inibitore della ricaptazione della serotonina |
EP3010586A1 (en) | 2013-06-21 | 2016-04-27 | Lupin Limited | Substituted heterocyclic compounds as crac modulators |
US9790231B2 (en) | 2013-06-24 | 2017-10-17 | Lupin Limited | Chromane and chromene derivatives and their use as CRAC modulators |
CN104337812B (zh) | 2013-07-29 | 2018-09-14 | 广东东阳光药业有限公司 | 取代的杂芳基化合物及其使用方法和用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2692264B1 (fr) * | 1992-06-12 | 1994-08-05 | Adir | Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant. |
EP0900792B1 (en) * | 1997-09-02 | 2003-10-29 | Duphar International Research B.V | Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists |
AU3386199A (en) * | 1998-04-08 | 1999-10-25 | American Home Products Corporation | N-aryloxyethyl-indoly-alkylamines for the treatment of depression (5-ht1a receptor active agents) |
AU765317C (en) * | 1998-06-19 | 2004-05-20 | H. Lundbeck A/S | 4,5,6 and 7-indole and indoline derivatives, their preparation and use |
AR022303A1 (es) * | 1999-01-22 | 2002-09-04 | Lundbeck & Co As H | Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion |
BR0013498A (pt) * | 1999-08-23 | 2002-05-14 | Solvay Pharm Bv | Composto, método para a preparação do mesmo, composição farmacêutica, e, métodos para a preparação da mesma e para o tratamento de distúrbios do snc |
KR20050085472A (ko) * | 2002-12-10 | 2005-08-29 | 메르크 파텐트 게엠베하 | 인돌 유도체 및 5-ht 리간드로서의 이의 용도 |
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2005
- 2005-12-06 ES ES05850037T patent/ES2311245T3/es active Active
- 2005-12-06 KR KR1020077013015A patent/KR20070085959A/ko not_active Application Discontinuation
- 2005-12-06 AU AU2005313311A patent/AU2005313311A1/en not_active Abandoned
- 2005-12-06 WO PCT/EP2005/056507 patent/WO2006061378A1/en active Application Filing
- 2005-12-06 KR KR1020077013063A patent/KR20070085988A/ko not_active Application Discontinuation
- 2005-12-06 ES ES05816322T patent/ES2317335T3/es active Active
- 2005-12-06 CA CA002587202A patent/CA2587202A1/en not_active Abandoned
- 2005-12-06 EP EP05816324A patent/EP1824480A1/en not_active Withdrawn
- 2005-12-06 JP JP2007544896A patent/JP2008523030A/ja not_active Withdrawn
- 2005-12-06 SI SI200530566T patent/SI1824479T1/sl unknown
- 2005-12-06 AU AU2005313390A patent/AU2005313390A1/en not_active Abandoned
- 2005-12-06 KR KR1020077012935A patent/KR20070085916A/ko not_active Application Discontinuation
- 2005-12-06 RU RU2007125659/04A patent/RU2007125659A/ru not_active Application Discontinuation
- 2005-12-06 AU AU2005313312A patent/AU2005313312A1/en not_active Abandoned
- 2005-12-06 DE DE602005008471T patent/DE602005008471D1/de not_active Expired - Fee Related
- 2005-12-06 WO PCT/EP2005/056505 patent/WO2006061376A1/en active IP Right Grant
- 2005-12-06 AT AT05816322T patent/ATE413173T1/de not_active IP Right Cessation
- 2005-12-06 KR KR1020077013041A patent/KR20070085975A/ko not_active Application Discontinuation
- 2005-12-06 EP EP05816322A patent/EP1824479B1/en active Active
- 2005-12-06 RU RU2007125658/04A patent/RU2007125658A/ru not_active Application Discontinuation
- 2005-12-06 WO PCT/EP2005/056506 patent/WO2006061377A1/en active Application Filing
- 2005-12-06 DK DK05850037T patent/DK1827427T3/da active
- 2005-12-06 EP EP05813645A patent/EP1827426A1/en not_active Withdrawn
- 2005-12-06 PL PL05850037T patent/PL1827427T3/pl unknown
- 2005-12-06 AU AU2005313391A patent/AU2005313391A1/en not_active Abandoned
- 2005-12-06 DK DK05816322T patent/DK1824479T3/da active
- 2005-12-06 CA CA002587381A patent/CA2587381A1/en not_active Abandoned
- 2005-12-06 CA CA002587559A patent/CA2587559A1/en not_active Abandoned
- 2005-12-06 JP JP2007544898A patent/JP2008537725A/ja not_active Withdrawn
- 2005-12-06 BR BRPI0518613-7A patent/BRPI0518613A2/pt not_active IP Right Cessation
- 2005-12-06 DE DE602005010902T patent/DE602005010902D1/de not_active Expired - Fee Related
- 2005-12-06 RU RU2007125660/04A patent/RU2007125660A/ru not_active Application Discontinuation
- 2005-12-06 WO PCT/EP2005/056508 patent/WO2006061379A1/en active Application Filing
- 2005-12-06 PT PT05816322T patent/PT1824479E/pt unknown
- 2005-12-06 EP EP05850037A patent/EP1827427B1/en active Active
- 2005-12-06 PL PL05816322T patent/PL1824479T3/pl unknown
- 2005-12-06 RU RU2007125661/04A patent/RU2007125661A/ru not_active Application Discontinuation
- 2005-12-06 AT AT05850037T patent/ATE401883T1/de not_active IP Right Cessation
- 2005-12-06 JP JP2007544897A patent/JP2008523031A/ja not_active Withdrawn
- 2005-12-06 PT PT05850037T patent/PT1827427E/pt unknown
- 2005-12-06 SI SI200530416T patent/SI1827427T1/sl unknown
- 2005-12-06 CA CA002587357A patent/CA2587357A1/en not_active Abandoned
- 2005-12-06 JP JP2007544895A patent/JP2008523029A/ja not_active Withdrawn
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2007
- 2007-05-08 IL IL183063A patent/IL183063A0/en unknown
- 2007-05-08 IL IL183064A patent/IL183064A0/en unknown
- 2007-05-08 IL IL183062A patent/IL183062A0/en unknown
- 2007-05-08 IL IL183061A patent/IL183061A0/en unknown
- 2007-06-11 NO NO20072969A patent/NO20072969L/no not_active Application Discontinuation
- 2007-06-11 NO NO20072977A patent/NO20072977L/no not_active Application Discontinuation
- 2007-06-11 NO NO20072981A patent/NO20072981L/no not_active Application Discontinuation
- 2007-06-11 NO NO20072974A patent/NO20072974L/no not_active Application Discontinuation
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2008
- 2008-10-22 HR HR20080538T patent/HRP20080538T3/xx unknown
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2009
- 2009-01-13 HR HR20090015T patent/HRP20090015T3/xx unknown
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