SI0854879T1 - Novel 5-o-deosaminyl 6-o-methyl erythronolide a derivatives, preparation method therefor and use thereof for preparing biologically active materials - Google Patents

Novel 5-o-deosaminyl 6-o-methyl erythronolide a derivatives, preparation method therefor and use thereof for preparing biologically active materials

Info

Publication number: SI0854879T1
Authority: SI; Slovenia
Prior art keywords: deosaminyl; derivatives; novel; preparation; biologically active
Prior art date: 1995-10-09

Application number

SI9630452T

Other languages

English (en)

Slovenian (sl)

Inventor

Alain Bonnet

Bernadette Chappert

Jacques Lagouardat

Original Assignee

Aventis Pharma S.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-09

Filing date

1996-10-08

Publication date

2002-08-31

1996-10-08 Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.

2002-08-31 Publication of SI0854879T1 publication Critical patent/SI0854879T1/xx

Links

239000011149 active material Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

SI9630452T 1995-10-09 1996-10-08 Novel 5-o-deosaminyl 6-o-methyl erythronolide a derivatives, preparation method therefor and use thereof for preparing biologically active materials SI0854879T1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR9511861A FR2739620B1 (fr)	1995-10-09	1995-10-09	Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
EP96933501A EP0854879B1 (fr)	1995-10-09	1996-10-08	Nouveaux derives de la 5-o-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
PCT/FR1996/001567 WO1997013774A2 (fr)	1995-10-09	1996-10-08	Nouveaux derives de la 5-o-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs

Publications (1)

Publication Number	Publication Date
SI0854879T1 true SI0854879T1 (en)	2002-08-31

Family

ID=9483377

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9630452T SI0854879T1 (en)	1995-10-09	1996-10-08	Novel 5-o-deosaminyl 6-o-methyl erythronolide a derivatives, preparation method therefor and use thereof for preparing biologically active materials

Country Status (33)

Country	Link
US (1)	US6011142A (no)
EP (1)	EP0854879B1 (no)
JP (1)	JP4327248B2 (no)
KR (1)	KR100451063B1 (no)
CN (1)	CN1067401C (no)
AP (1)	AP888A (no)
AR (1)	AR004688A1 (no)
AT (1)	ATE212034T1 (no)
AU (1)	AU708351B2 (no)
BG (1)	BG63752B1 (no)
BR (1)	BR9610959A (no)
CA (1)	CA2231562C (no)
CZ (1)	CZ293430B6 (no)
DE (1)	DE69618607T2 (no)
DK (1)	DK0854879T3 (no)
EA (1)	EA000765B1 (no)
EE (1)	EE03878B1 (no)
ES (1)	ES2171722T3 (no)
FR (1)	FR2739620B1 (no)
GE (1)	GEP20032899B (no)
HU (1)	HUP9900136A3 (no)
IL (1)	IL123613A0 (no)
MX (1)	MX9802655A (no)
NO (1)	NO312592B1 (no)
PL (1)	PL183645B1 (no)
PT (1)	PT854879E (no)
RO (1)	RO118874B1 (no)
SI (1)	SI0854879T1 (no)
SK (1)	SK283619B6 (no)
TR (1)	TR199800624T1 (no)
UA (1)	UA52621C2 (no)
WO (1)	WO1997013774A2 (no)
ZA (1)	ZA966666B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2777282B1 (fr) *	1998-04-08	2001-04-20	Hoechst Marion Roussel Inc	Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
US6590083B1 (en)	1999-04-16	2003-07-08	Ortho-Mcneil Pharmaceutical, Inc.	Ketolide antibacterials
KR20020007374A (ko) *	1999-04-16	2002-01-26	추후제출	매크롤라이드 항감염제
WO2000062783A2 (en)	1999-04-16	2000-10-26	Ortho-Mcneil Pharmaceutical, Inc.	Ketolide antibacterials
GB0031312D0 (en) *	2000-12-21	2001-02-07	Glaxo Group Ltd	Macrolides
EP2664331B1 (en)	2003-03-10	2015-09-16	Merck Sharp & Dohme Corp.	Novel Antibacterial Agents
EP2214484A4 (en) *	2007-10-25	2013-01-02	Cempra Pharmaceuticals Inc	PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
JP5602748B2 (ja) *	2008-10-24	2014-10-08	センプラファーマシューティカルズ，インコーポレイテッド	トリアゾール含有マクロライドを用いた生体防御
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en)	2009-09-10	2016-01-07	Cempra Pharmaceuticals, Inc.	Methods for treating malaria, tuberculosis and MAC diseases
BR112012023950A2 (pt)	2010-03-22	2016-07-05	Cempra Pharmaceuticals Inc	formas cristalinas de um macrolídeo, e usos dos mesmos
WO2011146829A1 (en)	2010-05-20	2011-11-24	Cempra Pharmaceuticals, Inc.	Processes for preparing macrolides and ketolides and intermediates therefor
KR20130120458A (ko)	2010-09-10	2013-11-04	셈프라 파마슈티컬스, 인크.	질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
KR20140139083A (ko)	2012-03-27	2014-12-04	셈프라 파마슈티컬스, 인크.	마크롤라이드계 항생제를 투여하기 위한 비경구 제제
JP6426696B2 (ja)	2013-03-14	2018-11-21	センプラファーマシューティカルズ，インコーポレイテッド	呼吸器疾患の治療のための方法および製剤
RU2015138797A (ru)	2013-03-15	2017-04-24	Семпра Фармасьютикалс, Инк.	Конвергентные способы получения макролидных антибактериальных агентов

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3923784A (en) *	1973-09-10	1975-12-02	Hoffmann La Roche	Erythromycin a derivatives
US4518590A (en) *	1984-04-13	1985-05-21	Pfizer Inc.	9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4742049A (en) *	1986-06-04	1988-05-03	Abbott Laboratories	Semisynthetic erythromycin antibiotics
PT86800B (pt) *	1987-02-24	1992-05-29	Beecham Group Plc	Processo para a preparacao de derivados de eritromicina
US5523399A (en) *	1991-12-27	1996-06-04	Taisho Pharmaceutical Co., Ltd.	5-O-desosaminylerythronolide derivatives
DK0638584T3 (da) *	1992-04-22	1996-04-15	Taisho Pharmaceutical Co Ltd	5-O-desosaminyl-erythronolid-A-derivat
FR2692579B1 (fr) *	1992-06-19	1995-06-02	Roussel Uclaf	Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
CA2154550A1 (en) *	1993-01-26	1994-08-04	Yoko Misawa	5-o-desosaminylerythronolide derivatives

1995
- 1995-10-09 FR FR9511861A patent/FR2739620B1/fr not_active Expired - Fee Related
1996
- 1996-08-06 ZA ZA9606666A patent/ZA966666B/xx unknown
- 1996-08-10 UA UA98041836A patent/UA52621C2/uk unknown
- 1996-10-07 AR ARP960104634A patent/AR004688A1/es not_active Application Discontinuation
- 1996-10-08 ES ES96933501T patent/ES2171722T3/es not_active Expired - Lifetime
- 1996-10-08 DE DE69618607T patent/DE69618607T2/de not_active Expired - Lifetime
- 1996-10-08 AP APAP/P/1998/001216A patent/AP888A/en active
- 1996-10-08 SK SK431-98A patent/SK283619B6/sk unknown
- 1996-10-08 DK DK96933501T patent/DK0854879T3/da active
- 1996-10-08 US US09/051,378 patent/US6011142A/en not_active Ceased
- 1996-10-08 AU AU72208/96A patent/AU708351B2/en not_active Expired
- 1996-10-08 KR KR10-1998-0702581A patent/KR100451063B1/ko not_active IP Right Cessation
- 1996-10-08 BR BR9610959A patent/BR9610959A/pt not_active Application Discontinuation
- 1996-10-08 SI SI9630452T patent/SI0854879T1/xx unknown
- 1996-10-08 EE EE9800109A patent/EE03878B1/xx not_active IP Right Cessation
- 1996-10-08 IL IL12361396A patent/IL123613A0/xx not_active IP Right Cessation
- 1996-10-08 CA CA002231562A patent/CA2231562C/fr not_active Expired - Lifetime
- 1996-10-08 EA EA199800280A patent/EA000765B1/ru not_active IP Right Cessation
- 1996-10-08 GE GEAP19964227A patent/GEP20032899B/en unknown
- 1996-10-08 WO PCT/FR1996/001567 patent/WO1997013774A2/fr not_active Application Discontinuation
- 1996-10-08 JP JP51476697A patent/JP4327248B2/ja not_active Expired - Lifetime
- 1996-10-08 EP EP96933501A patent/EP0854879B1/fr not_active Expired - Lifetime
- 1996-10-08 RO RO98-00826A patent/RO118874B1/ro unknown
- 1996-10-08 TR TR1998/00624T patent/TR199800624T1/xx unknown
- 1996-10-08 PL PL96326001A patent/PL183645B1/pl not_active IP Right Cessation
- 1996-10-08 AT AT96933501T patent/ATE212034T1/de active
- 1996-10-08 CZ CZ19981055A patent/CZ293430B6/cs not_active IP Right Cessation
- 1996-10-08 HU HU9900136A patent/HUP9900136A3/hu unknown
- 1996-10-08 CN CN96197514A patent/CN1067401C/zh not_active Expired - Lifetime
- 1996-10-08 PT PT96933501T patent/PT854879E/pt unknown
1998
- 1998-03-25 BG BG102350A patent/BG63752B1/bg unknown
- 1998-04-03 MX MX9802655A patent/MX9802655A/es unknown
- 1998-04-08 NO NO19981630A patent/NO312592B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO981630L (no)	1998-04-08
DE69618607D1 (de)	2002-02-21
AP888A (en)	2000-11-10
SK43198A3 (en)	1998-11-04
KR19990064100A (ko)	1999-07-26
MX9802655A (es)	1998-11-30
AU708351B2 (en)	1999-08-05
CN1199403A (zh)	1998-11-18
NO312592B1 (no)	2002-06-03
ZA966666B (en)	1997-08-06
TR199800624T1 (xx)	1998-06-22
UA52621C2 (uk)	2003-01-15
AR004688A1 (es)	1999-03-10
WO1997013774A3 (fr)	1997-05-29
GEP20032899B (en)	2003-02-25
DK0854879T3 (da)	2002-05-06
CZ293430B6 (cs)	2004-04-14
PT854879E (pt)	2002-07-31
WO1997013774A2 (fr)	1997-04-17
EE03878B1 (et)	2002-10-15
PL326001A1 (en)	1998-08-17
AU7220896A (en)	1997-04-30
BG63752B1 (bg)	2002-11-29
PL183645B1 (pl)	2002-06-28
CZ105598A3 (cs)	1998-07-15
BG102350A (en)	1999-03-31
CA2231562A1 (fr)	1997-04-17
JP4327248B2 (ja)	2009-09-09
US6011142A (en)	2000-01-04
ATE212034T1 (de)	2002-02-15
SK283619B6 (sk)	2003-10-07
IL123613A0 (en)	1998-10-30
ES2171722T3 (es)	2002-09-16
RO118874B1 (ro)	2003-12-30
EE9800109A (et)	1998-10-15
CN1067401C (zh)	2001-06-20
HUP9900136A3 (en)	2000-04-28
NO981630D0 (no)	1998-04-08
EP0854879A2 (fr)	1998-07-29
EP0854879B1 (fr)	2002-01-16
DE69618607T2 (de)	2002-08-14
EA000765B1 (ru)	2000-04-24
EA199800280A1 (ru)	1998-10-29
HUP9900136A1 (hu)	1999-05-28
CA2231562C (fr)	2006-11-28
BR9610959A (pt)	1999-03-02
KR100451063B1 (ko)	2004-12-17
FR2739620A1 (fr)	1997-04-11
FR2739620B1 (fr)	1997-12-19
JPH11513401A (ja)	1999-11-16

Publication	Publication Date	Title
HUP9802930A3 (en)	1999-12-28	Novel 5-o-deoaminyl 6-o-methyl erythronolide a derivatives, method for preparing same and application thereof for preparing biologically active products
HU9503505D0 (en)	1996-02-28	Novel erythromycin derivatives, method for preparing same and use thereof as drugs
HU9603038D0 (en)	1997-01-28	Novel erythromycin derivatives, method for their preparation and their use as drugs
HUP9900136A3 (en)	2000-04-28	Novel 5-o-deosaminyl 6-o-methyl erythronolide a derivatives, preparation method therefor and use thereof for preparing biologically active materials
IL125622A0 (en)	1999-04-11	Novel erythromycin derivatives method for preparing same and use thereof as drugs
HUP0002252A3 (en)	2002-01-28	9-oxime erythromycin derivatives, process for preparing them and pharmaceutical compositions containing them
AU5625696A (en)	1997-01-09	Stable vaccine compositions for parenteral administration, a method for their use, and a process for their preparation
IL132761A0 (en)	2001-03-19	Crystalline macrolides and process for their preparation
LTIP599A (en)	1994-07-15	Novel, biologically active eburnamenine derivatives and a process for preparing the same
HUP9903733A3 (en)	2000-07-28	New phenylamidine derivatives, a process for preparing the same and their use as medicaments
NZ328979A (en)	1998-10-28	Ring-contracted n-demethyl-n-isopropyl-spiroacetyl derivatives of erythromycin a (10,13,15-trioxatricyclo [9.2.1.1 9.6] -pentadecanone derivatives), method of preparation and pharmaceutical compositions thereof
AU7569796A (en)	1997-06-11	Multivalent polymers, processes for their preparation, and their use for preparing biologically active compounds.
HUP9903424A3 (en)	2001-04-28	Novel erythromycin derivatives,method for preparing same and use thereof as drugs
HUP0001180A3 (en)	2003-05-28	Novel erythromycin derivatives, method for preparing them and their use as medicine
AU5667998A (en)	1998-07-17	New derivatives of erythromycin, a method for preparing them, and their use as medicines
ZA961986B (en)	1996-11-21	Phosponomonoester nucleic acids, process for their preparation, and their use
HUP9904048A3 (en)	2001-08-28	4,10-betha-diacetoxy-2alfa-benzoyloxy-5betha,20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa[g]tax-11-ene-13alpha-yl (2r,3s)-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate dihydrate, and method for preparing same
HUP9902905A3 (en)	2001-06-28	Erythromycins and process for their preparation