EE9800109A - 5-O-desosaminüül-6-O-metüülerütronoliid A uued derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks - Google Patents

5-O-desosaminüül-6-O-metüülerütronoliid A uued derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks

Info

Publication number: EE9800109A
Authority: EE; Estonia
Prior art keywords: preparation; methylerythronolide; desosaminyl; new derivatives; bioactive products
Prior art date: 1995-10-09

Application number

EE9800109A

Other languages

English (en)

Other versions

EE03878B1 (et

Inventor

Bonnet Alain

Chappert Bernadette

Lagouardat Jacques

Original Assignee

Hoechst Marion Roussel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-09

Filing date

1996-10-08

Publication date

1998-10-15

1996-10-08 Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel

1998-10-15 Publication of EE9800109A publication Critical patent/EE9800109A/et

2002-10-15 Publication of EE03878B1 publication Critical patent/EE03878B1/et

Links

238000002360 preparation method Methods 0.000 title 2
QTLYNHBYTKOXTE-HLJDHPTISA-N [H][C@@]1(O[C@@H]2[C@@H](C)[C@H](O)[C@@H](C)C(=O)OC(CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)OC)O[C@H](C)C[C@@H]([C@H]1O)N(C)C Chemical class [H][C@@]1(O[C@@H]2[C@@H](C)[C@H](O)[C@@H](C)C(=O)OC(CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)OC)O[C@H](C)C[C@@H]([C@H]1O)N(C)C QTLYNHBYTKOXTE-HLJDHPTISA-N 0.000 title 1
230000000975 bioactive effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

EE9800109A 1995-10-09 1996-10-08 5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete ühendite valmistamiseks EE03878B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9511861A FR2739620B1 (fr)	1995-10-09	1995-10-09	Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
PCT/FR1996/001567 WO1997013774A2 (fr)	1995-10-09	1996-10-08	Nouveaux derives de la 5-o-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs

Publications (2)

Publication Number	Publication Date
EE9800109A true EE9800109A (et)	1998-10-15
EE03878B1 EE03878B1 (et)	2002-10-15

Family

ID=9483377

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9800109A EE03878B1 (et)	1995-10-09	1996-10-08	5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete ühendite valmistamiseks

Country Status (33)

Country	Link
US (1)	US6011142A (et)
EP (1)	EP0854879B1 (et)
JP (1)	JP4327248B2 (et)
KR (1)	KR100451063B1 (et)
CN (1)	CN1067401C (et)
AP (1)	AP888A (et)
AR (1)	AR004688A1 (et)
AT (1)	ATE212034T1 (et)
AU (1)	AU708351B2 (et)
BG (1)	BG63752B1 (et)
BR (1)	BR9610959A (et)
CA (1)	CA2231562C (et)
CZ (1)	CZ293430B6 (et)
DE (1)	DE69618607T2 (et)
DK (1)	DK0854879T3 (et)
EA (1)	EA000765B1 (et)
EE (1)	EE03878B1 (et)
ES (1)	ES2171722T3 (et)
FR (1)	FR2739620B1 (et)
GE (1)	GEP20032899B (et)
HU (1)	HUP9900136A3 (et)
IL (1)	IL123613A0 (et)
MX (1)	MX9802655A (et)
NO (1)	NO312592B1 (et)
PL (1)	PL183645B1 (et)
PT (1)	PT854879E (et)
RO (1)	RO118874B1 (et)
SI (1)	SI0854879T1 (et)
SK (1)	SK283619B6 (et)
TR (1)	TR199800624T1 (et)
UA (1)	UA52621C2 (et)
WO (1)	WO1997013774A2 (et)
ZA (1)	ZA966666B (et)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2777282B1 (fr) *	1998-04-08	2001-04-20	Hoechst Marion Roussel Inc	Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
KR100710605B1 (ko) *	1999-04-16	2007-04-24	코산 바이오사이언시즈, 인코포레이티드	매크롤라이드 항감염제
US6590083B1 (en)	1999-04-16	2003-07-08	Ortho-Mcneil Pharmaceutical, Inc.	Ketolide antibacterials
IL145976A0 (en)	1999-04-16	2002-07-25	Ortho Mcneil Pharm Inc	Ketolide antibacterials
GB0031312D0 (en) *	2000-12-21	2001-02-07	Glaxo Group Ltd	Macrolides
US7601695B2 (en) *	2003-03-10	2009-10-13	Optimer Pharmaceuticals, Inc.	Antibacterial agents
WO2009055557A1 (en)	2007-10-25	2009-04-30	Cempra Pharmaceuticals, Inc.	Process for the preparation of macrolide antibacterial agents
US8796232B2 (en)	2008-10-24	2014-08-05	Cempra Pharmaceuticals, Inc.	Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja)	2009-09-10	2016-05-11	センプラファーマシューティカルズ，インコーポレイテッド	マラリア、結核、及びｍａｃ病の治療方法
WO2011119604A1 (en)	2010-03-22	2011-09-29	Cempra Pharmaceuticals, Inc.	Crystalline forms of a macrolide, and uses therefor
BR112012029586A2 (pt)	2010-05-20	2016-08-02	Cempra Pharmaceuticals Inc	processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20180110181A (ko)	2010-09-10	2018-10-08	셈프라 파마슈티컬스, 인크.	질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
CA2868262A1 (en)	2012-03-27	2013-10-03	Cempra Pharmaceuticals, Inc.	Parenteral formulations for administering macrolide antibiotics
CN105163785A (zh)	2013-03-14	2015-12-16	森普拉制药公司	用于治疗呼吸道疾病的方法及其制剂
CA2907085A1 (en)	2013-03-15	2014-09-18	Cempra Pharmaceuticals, Inc.	Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3923784A (en) *	1973-09-10	1975-12-02	Hoffmann La Roche	Erythromycin a derivatives
US4518590A (en) *	1984-04-13	1985-05-21	Pfizer Inc.	9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4742049A (en) *	1986-06-04	1988-05-03	Abbott Laboratories	Semisynthetic erythromycin antibiotics
KR880009960A (ko) *	1987-02-24	1988-10-06	데이빗 로버츠	화학적 화합물
US5523399A (en) *	1991-12-27	1996-06-04	Taisho Pharmaceutical Co., Ltd.	5-O-desosaminylerythronolide derivatives
US5591837A (en) *	1992-04-22	1997-01-07	Taisho Pharmaceutical Co., Ltd.	5-O-desosaminylerythronolide a derivative
FR2692579B1 (fr) *	1992-06-19	1995-06-02	Roussel Uclaf	Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
CA2154550A1 (en) *	1993-01-26	1994-08-04	Yoko Misawa	5-o-desosaminylerythronolide derivatives

1995
- 1995-10-09 FR FR9511861A patent/FR2739620B1/fr not_active Expired - Fee Related
1996
- 1996-08-06 ZA ZA9606666A patent/ZA966666B/xx unknown
- 1996-08-10 UA UA98041836A patent/UA52621C2/uk unknown
- 1996-10-07 AR ARP960104634A patent/AR004688A1/es not_active Application Discontinuation
- 1996-10-08 AU AU72208/96A patent/AU708351B2/en not_active Expired
- 1996-10-08 US US09/051,378 patent/US6011142A/en not_active Ceased
- 1996-10-08 EE EE9800109A patent/EE03878B1/et not_active IP Right Cessation
- 1996-10-08 AP APAP/P/1998/001216A patent/AP888A/en active
- 1996-10-08 PT PT96933501T patent/PT854879E/pt unknown
- 1996-10-08 EP EP96933501A patent/EP0854879B1/fr not_active Expired - Lifetime
- 1996-10-08 TR TR1998/00624T patent/TR199800624T1/xx unknown
- 1996-10-08 DK DK96933501T patent/DK0854879T3/da active
- 1996-10-08 HU HU9900136A patent/HUP9900136A3/hu unknown
- 1996-10-08 CA CA002231562A patent/CA2231562C/fr not_active Expired - Lifetime
- 1996-10-08 EA EA199800280A patent/EA000765B1/ru not_active IP Right Cessation
- 1996-10-08 CZ CZ19981055A patent/CZ293430B6/cs not_active IP Right Cessation
- 1996-10-08 GE GEAP19964227A patent/GEP20032899B/en unknown
- 1996-10-08 ES ES96933501T patent/ES2171722T3/es not_active Expired - Lifetime
- 1996-10-08 IL IL12361396A patent/IL123613A0/xx not_active IP Right Cessation
- 1996-10-08 KR KR10-1998-0702581A patent/KR100451063B1/ko not_active IP Right Cessation
- 1996-10-08 JP JP51476697A patent/JP4327248B2/ja not_active Expired - Lifetime
- 1996-10-08 PL PL96326001A patent/PL183645B1/pl not_active IP Right Cessation
- 1996-10-08 RO RO98-00826A patent/RO118874B1/ro unknown
- 1996-10-08 SK SK431-98A patent/SK283619B6/sk unknown
- 1996-10-08 AT AT96933501T patent/ATE212034T1/de active
- 1996-10-08 SI SI9630452T patent/SI0854879T1/xx unknown
- 1996-10-08 CN CN96197514A patent/CN1067401C/zh not_active Expired - Lifetime
- 1996-10-08 BR BR9610959A patent/BR9610959A/pt not_active Application Discontinuation
- 1996-10-08 DE DE69618607T patent/DE69618607T2/de not_active Expired - Lifetime
- 1996-10-08 WO PCT/FR1996/001567 patent/WO1997013774A2/fr not_active Application Discontinuation
1998
- 1998-03-25 BG BG102350A patent/BG63752B1/bg unknown
- 1998-04-03 MX MX9802655A patent/MX9802655A/es unknown
- 1998-04-08 NO NO19981630A patent/NO312592B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
BG102350A (en)	1999-03-31
RO118874B1 (ro)	2003-12-30
CA2231562C (fr)	2006-11-28
UA52621C2 (uk)	2003-01-15
ZA966666B (en)	1997-08-06
AU708351B2 (en)	1999-08-05
HUP9900136A3 (en)	2000-04-28
PL183645B1 (pl)	2002-06-28
SK283619B6 (sk)	2003-10-07
AU7220896A (en)	1997-04-30
SI0854879T1 (en)	2002-08-31
PL326001A1 (en)	1998-08-17
SK43198A3 (en)	1998-11-04
GEP20032899B (en)	2003-02-25
FR2739620A1 (fr)	1997-04-11
ATE212034T1 (de)	2002-02-15
CA2231562A1 (fr)	1997-04-17
BR9610959A (pt)	1999-03-02
JP4327248B2 (ja)	2009-09-09
TR199800624T1 (xx)	1998-06-22
DE69618607T2 (de)	2002-08-14
ES2171722T3 (es)	2002-09-16
EA199800280A1 (ru)	1998-10-29
CN1067401C (zh)	2001-06-20
MX9802655A (es)	1998-11-30
CZ293430B6 (cs)	2004-04-14
NO981630D0 (no)	1998-04-08
AR004688A1 (es)	1999-03-10
IL123613A0 (en)	1998-10-30
WO1997013774A3 (fr)	1997-05-29
PT854879E (pt)	2002-07-31
CZ105598A3 (cs)	1998-07-15
KR100451063B1 (ko)	2004-12-17
WO1997013774A2 (fr)	1997-04-17
US6011142A (en)	2000-01-04
NO312592B1 (no)	2002-06-03
DK0854879T3 (da)	2002-05-06
BG63752B1 (bg)	2002-11-29
HUP9900136A1 (hu)	1999-05-28
FR2739620B1 (fr)	1997-12-19
EP0854879A2 (fr)	1998-07-29
DE69618607D1 (de)	2002-02-21
EP0854879B1 (fr)	2002-01-16
JPH11513401A (ja)	1999-11-16
EA000765B1 (ru)	2000-04-24
CN1199403A (zh)	1998-11-18
EE03878B1 (et)	2002-10-15
KR19990064100A (ko)	1999-07-26
AP888A (en)	2000-11-10
NO981630L (no)	1998-04-08

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Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2004-12-15	GB1A	Change in the ownership or in the address of the owner
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2007-06-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20061008