ZA961986B - Phosponomonoester nucleic acids, process for their preparation, and their use - Google Patents

Phosponomonoester nucleic acids, process for their preparation, and their use

Info

Publication number
ZA961986B
ZA961986B ZA961986A ZA961986A ZA961986B ZA 961986 B ZA961986 B ZA 961986B ZA 961986 A ZA961986 A ZA 961986A ZA 961986 A ZA961986 A ZA 961986A ZA 961986 B ZA961986 B ZA 961986B
Authority
ZA
South Africa
Prior art keywords
phosponomonoester
preparation
nucleic acids
nucleic
acids
Prior art date
Application number
ZA961986A
Inventor
Anuschirwan Peyman
Eugen Uhlmann
Gerhard Breipohl
Holger Wallmeier
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA961986B publication Critical patent/ZA961986B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4071Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4087Esters with arylalkanols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C07K14/003Peptide-nucleic acids (PNAs)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA961986A 1995-03-13 1996-03-12 Phosponomonoester nucleic acids, process for their preparation, and their use ZA961986B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19508923A DE19508923A1 (en) 1995-03-13 1995-03-13 New oligo:nucleotide analogues contg. phospho:mono:ester bridges

Publications (1)

Publication Number Publication Date
ZA961986B true ZA961986B (en) 1996-11-21

Family

ID=7756476

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA961986A ZA961986B (en) 1995-03-13 1996-03-12 Phosponomonoester nucleic acids, process for their preparation, and their use

Country Status (2)

Country Link
DE (1) DE19508923A1 (en)
ZA (1) ZA961986B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19909373A1 (en) * 1999-03-03 2000-10-05 Ugichem New PNA monomers, resulting PNA oligomers and their use
GB9929487D0 (en) * 1999-12-15 2000-02-09 Zeneca Ltd Antisense oligonucleotides
DE10019135A1 (en) 2000-04-18 2001-10-31 Aventis Pharma Gmbh Polyamide nucleic acid derivatives, agents and processes for their preparation
DE10019136A1 (en) * 2000-04-18 2001-10-31 Aventis Pharma Gmbh Polyamide nucleic acid derivatives, agents and processes for their preparation

Also Published As

Publication number Publication date
DE19508923A1 (en) 1996-09-19

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