SI0787726T1 - Novel compound, process for producing the same, and antitumor agent - Google Patents

Novel compound, process for producing the same, and antitumor agent

Info

Publication number
SI0787726T1
SI0787726T1 SI9530567T SI9530567T SI0787726T1 SI 0787726 T1 SI0787726 T1 SI 0787726T1 SI 9530567 T SI9530567 T SI 9530567T SI 9530567 T SI9530567 T SI 9530567T SI 0787726 T1 SI0787726 T1 SI 0787726T1
Authority
SI
Slovenia
Prior art keywords
hydrogen atom
producing
same
group
lower alkyl
Prior art date
Application number
SI9530567T
Other languages
English (en)
Slovenian (sl)
Inventor
Kyoji Tomita
Katsumi Chiba
Shigeki Kashimoto
Koh-Ichiro Shibamori
Yasunori Tsuzuki
Original Assignee
Dainippon Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co., Ltd. filed Critical Dainippon Pharmaceutical Co., Ltd.
Publication of SI0787726T1 publication Critical patent/SI0787726T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI9530567T 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent SI0787726T1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP15657894 1994-06-14
JP19792194 1994-07-28
JP30691494 1994-11-15
JP33995694 1994-12-28
JP8170595 1995-03-13
PCT/JP1995/001110 WO1995034559A1 (fr) 1994-06-14 1995-06-06 Nouveau compose, son procede de production et agent antitumoral
EP95920265A EP0787726B1 (en) 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent

Publications (1)

Publication Number Publication Date
SI0787726T1 true SI0787726T1 (en) 2002-04-30

Family

ID=27524935

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9530567T SI0787726T1 (en) 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent

Country Status (27)

Country Link
US (1) US5817669A (da)
EP (1) EP0787726B1 (da)
JP (1) JP3391796B2 (da)
KR (1) KR100350921B1 (da)
CN (1) CN1053668C (da)
AT (1) ATE209645T1 (da)
AU (1) AU679859B2 (da)
BR (1) BR9508037A (da)
CA (1) CA2192824C (da)
CZ (1) CZ292631B6 (da)
DE (1) DE69524251T2 (da)
DK (1) DK0787726T3 (da)
ES (1) ES2163512T3 (da)
FI (1) FI112485B (da)
HK (1) HK1000495A1 (da)
HU (1) HU220072B (da)
MX (1) MX9606331A (da)
NO (1) NO307255B1 (da)
NZ (1) NZ287139A (da)
PL (1) PL181867B1 (da)
PT (1) PT787726E (da)
RO (1) RO117793B1 (da)
RU (1) RU2151770C1 (da)
SI (1) SI0787726T1 (da)
SK (1) SK281341B6 (da)
TW (1) TW319769B (da)
WO (1) WO1995034559A1 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
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EP1432711A1 (en) * 2001-09-26 2004-06-30 Bayer Corporation 1,6-naphthyridine derivatives as antidiabetics
US6802423B2 (en) * 2002-02-20 2004-10-12 Trans Global Foods, Inc. Disposable food delivery apparatus
EP1610795A4 (en) * 2003-04-07 2007-10-24 Cylene Pharmaceuticals Inc SUBSTITUTED 1,4-DIHYDRO-4-OXO-1,8-NAPHTHPYRIDINE HETEROCYCLIC ANALOGUES
AU2004272414B2 (en) * 2003-09-10 2009-05-28 Kyorin Pharmaceutical Co., Ltd. 7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) quinolonecarboxylic acid derivative
DE10352979A1 (de) * 2003-11-13 2005-06-09 Merck Patent Gmbh Pyridopyrimidinone
ATE451924T1 (de) * 2004-03-15 2010-01-15 Sunesis Pharmaceuticals Inc Sns-595 und anwendungsverfahren
AU2013201203C1 (en) * 2004-03-15 2015-04-23 Sumitomo Dainippon Pharma Co., Ltd. Sns-595 and methods of using the same
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
EP1926372A2 (en) * 2005-08-19 2008-06-04 Cylene Pharmaceuticals, Inc. HUMAN RIBOSOMAL DNA(rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF
AU2013219242C1 (en) * 2005-09-02 2016-09-22 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
CN104873502A (zh) * 2005-09-02 2015-09-02 逊尼希思制药公司 使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
US8580814B2 (en) * 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
KR20080041298A (ko) * 2005-09-02 2008-05-09 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한(＋)-1,4-디히드로-7-[(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리디닐]-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
JP5374153B2 (ja) * 2005-09-02 2013-12-25 サネシス ファーマシューティカルズ， インコーポレイテッド 癌の治療のための（＋）−１，４−ジヒドロ−７−［（３ｓ，４ｓ）−３−メトキシ−４−（メチルアミノ）−１−ピロリジニル］−４−オキソ−１−（２−チアゾリル）−１，８−ナフチリジン−３−カルボン酸を使用する方法
CN101300258A (zh) * 2005-09-14 2008-11-05 詹森药业有限公司 作为c-fms激酶抑制剂的5-氧代-5,8-二氢-吡啶并-嘧啶类
US7642270B2 (en) 2005-09-14 2010-01-05 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
TW200800983A (en) 2005-09-14 2008-01-01 Janssen Pharmaceutica Nv 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase
EP2043645A2 (en) * 2006-06-12 2009-04-08 Sunesis Pharmaceuticals, Inc. Compounds and compositions for treatment of cancer
WO2008016678A2 (en) * 2006-08-01 2008-02-07 Sunesis Pharmaceuticals, Inc. Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
US20080063642A1 (en) * 2006-08-02 2008-03-13 Adelman Daniel C Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of certain hematologic disorders
CN103720701A (zh) * 2007-10-22 2014-04-16 逊尼希思制药公司 在联合治疗中使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸的方法
AU2008335772B2 (en) * 2007-12-10 2014-11-27 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3- methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1- (2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
EP2382214B1 (en) 2008-12-31 2017-07-19 Sunesis Pharmaceuticals, Inc. Method of preparing (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
KR20170046193A (ko) 2009-02-27 2017-04-28 선에시스 파마슈티컬스 인코포레이티드 감소된 ｂｒｃａ2 활성을 갖는 암 대상자의 치료를 위한 ｓｎｓ-595의 사용 방법
UA110465C2 (en) 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
TW201120037A (en) * 2009-10-26 2011-06-16 Sunesis Pharmaceuticals Inc Compounds and methods for treatment of cancer
LT2712358T (lt) 2011-05-13 2017-01-25 Array Biopharma, Inc. Pirolidinilkarbamido, pirolidiniltiokarbamido ir pirolidinilguanidino junginiai kaip trka kinazės inhibitoriai
CN103497186B (zh) * 2013-09-24 2015-02-25 浙江司太立制药股份有限公司 含有烷氧亚氨基取代的萘啶酮羧酸衍生物及其制备方法
CN110520422B (zh) * 2017-03-24 2023-09-05 涌永制药株式会社 新型吡啶酮羧酸衍生物或其盐

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
DE3577089D1 (de) * 1984-01-26 1990-05-17 Abbott Lab Antibakterielle chinolinderivate.
JPS61152682A (ja) * 1984-12-27 1986-07-11 Dainippon Pharmaceut Co Ltd ピリドンカルボン酸誘導体、そのエステルおよびその塩
JPS61251667A (ja) * 1985-04-30 1986-11-08 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環化合物
PT82752B (pt) * 1985-06-13 1988-12-15 Schering Corp Processo para a preparacao de derivados policiclicos de quinolina, naftiridina e pirazinopiridina
EP0226624A1 (en) * 1985-06-14 1987-07-01 The Upjohn Company Cyclopentapyrazole and tetrahydroindazole compounds
JPS6233176A (ja) * 1985-08-05 1987-02-13 Toyama Chem Co Ltd １，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩
JP2704428B2 (ja) * 1988-06-15 1998-01-26 富山化学工業株式会社 キノロンカルボン酸誘導体またはその塩
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
JPH06233176A (ja) * 1993-01-29 1994-08-19 Sony Corp ビデオカメラ

Also Published As

Publication number Publication date
HUT75777A (en) 1997-05-28
US5817669A (en) 1998-10-06
JP3391796B2 (ja) 2003-03-31
DK0787726T3 (da) 2002-02-11
FI112485B (fi) 2003-12-15
EP0787726B1 (en) 2001-11-28
KR100350921B1 (ko) 2002-11-18
MX9606331A (es) 1997-03-29
AU2576795A (en) 1996-01-05
EP0787726A4 (da) 1997-08-06
FI965020A (fi) 1996-12-16
SK157496A3 (en) 1997-08-06
NO965305L (no) 1997-02-04
CA2192824C (en) 2006-11-07
RO117793B1 (ro) 2002-07-30
RU2151770C1 (ru) 2000-06-27
NZ287139A (en) 1997-07-27
DE69524251T2 (de) 2002-07-11
EP0787726A1 (en) 1997-08-06
HK1000495A1 (en) 2002-07-19
PL317726A1 (en) 1997-04-28
BR9508037A (pt) 1997-09-16
SK281341B6 (sk) 2001-02-12
PL181867B1 (pl) 2001-09-28
DE69524251D1 (de) 2002-01-10
CA2192824A1 (en) 1995-12-21
WO1995034559A1 (fr) 1995-12-21
PT787726E (pt) 2002-04-29
CN1158614A (zh) 1997-09-03
NO307255B1 (no) 2000-03-06
TW319769B (da) 1997-11-11
ES2163512T3 (es) 2002-02-01
FI965020A0 (fi) 1996-12-13
ATE209645T1 (de) 2001-12-15
CN1053668C (zh) 2000-06-21
CZ292631B6 (cs) 2003-11-12
AU679859B2 (en) 1997-07-10
HU220072B (hu) 2001-10-28
CZ364396A3 (en) 1997-06-11
HU9603455D0 (en) 1997-02-28
NO965305D0 (no) 1996-12-11

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