SG11202010385RA - 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof - Google Patents

2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof

Info

Publication number
SG11202010385RA
SG11202010385RA SG11202010385RA SG11202010385RA SG11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA SG 11202010385R A SG11202010385R A SG 11202010385RA
Authority
SG
Singapore
Prior art keywords
triazole
propane
amino
novel compound
diol derivative
Prior art date
Application number
SG11202010385RA
Other languages
English (en)
Inventor
Jae-Sung Bae
Hee Kyung Jin
Min Hee Park
Original Assignee
Kyungpook Nat Univ Ind Academic Coop Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyungpook Nat Univ Ind Academic Coop Found filed Critical Kyungpook Nat Univ Ind Academic Coop Found
Publication of SG11202010385RA publication Critical patent/SG11202010385RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/045—Organic compounds containing nitrogen as heteroatom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG11202010385RA 2018-04-30 2019-04-25 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof SG11202010385RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020180050215A KR102017324B1 (ko) 2018-04-30 2018-04-30 신규한 asm 활성 직접 억제 화합물 2-아미노-2-(1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도
PCT/KR2019/005019 WO2019212196A1 (ko) 2018-04-30 2019-04-25 신규한 asm 활성 직접 억제 화합물 2-아미노-2-(1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도

Publications (1)

Publication Number Publication Date
SG11202010385RA true SG11202010385RA (en) 2020-11-27

Family

ID=67951278

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202010385RA SG11202010385RA (en) 2018-04-30 2019-04-25 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof

Country Status (14)

Country Link
US (1) US20210188784A1 (ko)
EP (1) EP3789380A4 (ko)
JP (1) JP7178029B2 (ko)
KR (1) KR102017324B1 (ko)
CN (1) CN112351974B (ko)
AU (1) AU2019264073B2 (ko)
BR (1) BR112020022141A2 (ko)
CA (1) CA3097685C (ko)
IL (1) IL278139B2 (ko)
MX (1) MX2020011490A (ko)
PH (1) PH12020551751A1 (ko)
RU (1) RU2759856C1 (ko)
SG (1) SG11202010385RA (ko)
WO (1) WO2019212196A1 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3661600A4 (en) 2017-10-23 2021-08-11 Epitracker, Inc. FATTY ACID ANALOGS AND ITS USE IN THE TREATMENT OF DISEASES RELATED TO METABOLISM SYNDROME
WO2019226572A1 (en) 2018-05-23 2019-11-28 Epitracker, Inc. Compositions and methods for diagnosis and treatment of conditions related to the quality of aging and longevity
JP7404382B2 (ja) * 2019-03-04 2023-12-25 エピトラッカー インコーポレイテッド 脂肪酸アナログ、ならびに認知機能障害、行動症状および慢性疼痛の処置におけるそれらの使用
WO2022065831A1 (ko) 2020-09-22 2022-03-31 경북대학교 산학협력단 그렐린 수용체 작용제로서의 트리아졸 화합물의 용도
AR125980A1 (es) * 2021-05-27 2023-08-30 Isu Abxis Co Ltd Anticuerpos específicamente unidos a la proteína asm
KR102563719B1 (ko) * 2021-09-15 2023-08-04 주식회사 넥스트젠바이오사이언스 S1pr1과 s1pr4에 대한 기능적 저해제로 작용하는 ifta 예방 또는 치료용 약학적 조성물
WO2023042996A1 (en) * 2021-09-15 2023-03-23 Nextgen Bioscience Pharmaceutical composition for preventing or treating focal segmental glomerulosclerosis acting as a functional antagonist for s1pr1 and s1pr4
CA3212009A1 (en) * 2022-03-23 2023-09-28 Eun Jeong Kim Pharmaceutical compositions comprising a functional antagonist of s1pr1 and s1pr4 for preventing and treating inflammatory bowel disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0722077D0 (en) * 2007-11-09 2007-12-19 Smithkline Beecham Corp Compounds
US8518942B2 (en) * 2008-08-06 2013-08-27 Buck Institute For Research On Aging Caspase inhibitors and uses thereof
JP2012505836A (ja) * 2008-10-17 2012-03-08 アカール ファーマ ピーティーワイ リミテッド Ｓ１ｐ受容体モジュレーターおよびそれらの使用
KR101521117B1 (ko) 2013-05-07 2015-05-18 경북대학교 산학협력단 Ａｓｍ 억제제를 유효성분으로 포함하는 퇴행성 신경질환의 예방 또는 치료용 조성물
WO2015188368A1 (en) * 2014-06-13 2015-12-17 Merck Sharp & Dohme Corp. Pyrrolo[2,3-c]pyridines as imaging agents for neurofibrilary tangles
KR101830244B1 (ko) * 2016-01-20 2018-02-21 서울대학교 산학협력단 신규한 헤테로방향족 고리 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 s1p 수용체 관련 질환의 예방 또는 치료용 약학적 조성물
KR20180036318A (ko) * 2016-09-30 2018-04-09 경북대학교 산학협력단 2-아미노-2-(1-도데실-1h-1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체를 유효성분으로 포함하는 퇴행성 신경질환 및 우울증 예방 또는 치료용 약학적 조성물
KR102130999B1 (ko) 2016-11-04 2020-07-09 주식회사 케이티 무선 통신에서 멀티 빔 기반 스케줄링 요청을 수행하는 방법 및 장치
KR101811436B1 (ko) * 2017-04-28 2017-12-21 경북대학교 산학협력단 신규 화합물 2-아미노-2-(1-(2-(2-히드록시에톡시)에틸)-1h-1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도

Also Published As

Publication number Publication date
JP2022514722A (ja) 2022-02-15
WO2019212196A1 (ko) 2019-11-07
PH12020551751A1 (en) 2021-07-26
MX2020011490A (es) 2021-02-18
CN112351974B (zh) 2024-01-26
CA3097685C (en) 2023-10-03
IL278139B1 (en) 2023-11-01
IL278139A (ko) 2020-12-31
BR112020022141A2 (pt) 2021-01-26
KR102017324B1 (ko) 2019-09-02
IL278139B2 (en) 2024-03-01
CN112351974A (zh) 2021-02-09
EP3789380A4 (en) 2021-12-22
EP3789380A1 (en) 2021-03-10
AU2019264073A1 (en) 2020-11-26
AU2019264073B2 (en) 2022-03-31
RU2759856C1 (ru) 2021-11-18
US20210188784A1 (en) 2021-06-24
CA3097685A1 (en) 2019-11-07
JP7178029B2 (ja) 2022-11-25

Similar Documents

Publication Publication Date Title
SG11202010385RA (en) 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting asm activity, and use thereof
IL279256A (en) Sulfonimidamide compounds as inhibitors of interleukin-1 activity
EA201791444A1 (ru) 5-фтор-4-имино-3-(алкил/замещенный алкил)-1-(арилсульфонил)-3,4-дигидропиримидин-2(1h)-он в качестве средства обработки семян
IL267961B1 (en) Chemical compounds such as interleukin-1 activity inhibitors
HK1248235A1 (zh) 具有作為吲哚胺2，3-二加氧酶抑制劑活性的苯並咪唑和咪唑並吡啶亞氨代甲酰胺化合物
EP3372595A4 (en) CONDENSED HETEROCYCLIC COMPOUND CONTAINING OXIME GROUP OR SALTS, AND AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING SAID COMPOUND AND METHOD OF USE
MX2018000050A (es) Fenoxihalogenofenilamidinas y su uso como fungicidas.
PH12018501543A1 (en) Fungicidal composition
MX2022007436A (es) Inhibidores de la autotaxina y sus usos.
MX2017001897A (es) Compuestos fusionados de 11 miembros y fungicidas agricolas/horticolas que los contienen.
EP3504185A4 (en) NEW SUBSTITUTED N'-HYDROXYCARBAMIMIDOYL-1,2,5-OXADIAZOLE COMPOUNDS AS INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE (IDO)
MX2017014459A (es) Compuestos de tioeter como inhibidores de la nitrificacion.
PH12017501135A1 (en) Active compound combinations
PH12017501136A1 (en) Active compound combinations
PH12017501110A1 (en) Active compound combinations comprising a (thio)carboxamide derivative and fungicidal compound(s)
PH12017501137A1 (en) Active compound combinations
BR112016002384A2 (pt) composto, composição de herbicida, método para controlar plantas indesejáveis, e, uso de um composto
EP3661909A4 (en) NEW SUBSTITUTED PHENYL COMPOUNDS USED AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS
EP3560928A4 (en) CONDENSED IMIDAZOLE COMPOUND WITH INDOLAMINE-2,3-DIOXYGENASE-INHIBITING EFFECT
EP3544965A4 (en) SULFOXIMIN, SULFONIMIDAMID, SULFONDIIMIN AND DIIMIDOSULFONAMID COMPOUNDS AS INHIBITORS OF INDOLAMINE-2,3-DIOXYGENASE
NZ765435A (en) Polymorphs
EP3600299A4 (en) NEW N'-HYDROXYCARBAMIMIDOYL-1,2,5-OXADIAZOLES SUBSTITUTED COMPOUNDS USED AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS
IL257168B (en) Use of 7-carboxybenzo[1,2,3]thiadiazole amides as plant stimulants
IT201700122788A1 (it) Impianto per la gestione di vassoi
EA201991932A1 (ru) Производное азитидина