SG10201703508QA - Isoindoline compounds for use in the treatment of cancer - Google Patents
Isoindoline compounds for use in the treatment of cancerInfo
- Publication number
- SG10201703508QA SG10201703508QA SG10201703508QA SG10201703508QA SG10201703508QA SG 10201703508Q A SG10201703508Q A SG 10201703508QA SG 10201703508Q A SG10201703508Q A SG 10201703508QA SG 10201703508Q A SG10201703508Q A SG 10201703508QA SG 10201703508Q A SG10201703508Q A SG 10201703508QA
- Authority
- SG
- Singapore
- Prior art keywords
- cancer
- treatment
- isoindoline compounds
- isoindoline
- compounds
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- GWVMLCQWXVFZCN-UHFFFAOYSA-N isoindoline Chemical class C1=CC=C2CNCC2=C1 GWVMLCQWXVFZCN-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10947508P | 2008-10-29 | 2008-10-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201703508QA true SG10201703508QA (en) | 2017-06-29 |
Family
ID=41328433
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201703508QA SG10201703508QA (en) | 2008-10-29 | 2009-10-26 | Isoindoline compounds for use in the treatment of cancer |
SG2013080114A SG195613A1 (en) | 2008-10-29 | 2009-10-26 | Isoindoline compounds for use in the treatment of cancer |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG2013080114A SG195613A1 (en) | 2008-10-29 | 2009-10-26 | Isoindoline compounds for use in the treatment of cancer |
Country Status (31)
Country | Link |
---|---|
US (6) | US8129375B2 (ja) |
EP (3) | EP3354646A1 (ja) |
JP (3) | JP5603876B2 (ja) |
KR (3) | KR101696938B1 (ja) |
CN (2) | CN104744434A (ja) |
AR (6) | AR074001A1 (ja) |
AU (1) | AU2009311477B2 (ja) |
BR (1) | BRPI0919942B1 (ja) |
CA (2) | CA2957226C (ja) |
CL (1) | CL2011000957A1 (ja) |
CO (1) | CO6361916A2 (ja) |
DK (1) | DK2358697T3 (ja) |
ES (2) | ES2662407T3 (ja) |
HK (1) | HK1154859A1 (ja) |
HR (1) | HRP20151366T1 (ja) |
HU (1) | HUE026105T2 (ja) |
IL (9) | IL212435A (ja) |
MX (2) | MX361467B (ja) |
NI (1) | NI201100082A (ja) |
NZ (1) | NZ592425A (ja) |
PE (2) | PE20140963A1 (ja) |
PL (1) | PL2358697T3 (ja) |
PT (1) | PT2358697E (ja) |
RU (1) | RU2527952C2 (ja) |
SG (2) | SG10201703508QA (ja) |
SI (1) | SI2358697T1 (ja) |
SM (1) | SMT201600025B (ja) |
TW (1) | TWI469974B (ja) |
UA (1) | UA107783C2 (ja) |
WO (1) | WO2010053732A1 (ja) |
ZA (1) | ZA201102941B (ja) |
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US8877780B2 (en) * | 2006-08-30 | 2014-11-04 | Celgene Corporation | 5-substituted isoindoline compounds |
EP2699091B1 (en) | 2011-03-28 | 2017-06-21 | DeuteRx, LLC | 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds |
US9540340B2 (en) | 2013-01-14 | 2017-01-10 | Deuterx, Llc | 3-(5-substituted-4-oxoquinazolin-3(4H)-yl)-3-deutero-piperidine-2,6-dione derivatives and compositions comprising and methods of using the same |
EP2968334A4 (en) | 2013-03-14 | 2016-08-03 | Deuterx Llc | 3- (SUBSTITIERTES-4-OXO-quinazolin-3 (4H) -yl) -3-deutero-PIPERIDINE-2,6-DIONE DERIVATIVES |
JP6389241B2 (ja) | 2013-04-17 | 2018-09-12 | シグナル ファーマシューティカルズ,エルエルシー | 癌を治療するためのTORキナーゼ阻害剤及びIMiD化合物を含む組合せ療法 |
MX2016007239A (es) | 2013-12-06 | 2017-01-05 | Celgene Corp | Metodos para determinar la eficacia del farmaco para el tratamiento de linfoma difuso de celulas b grandes, mieloma multiple, y canceres mieloides. |
JP6778114B2 (ja) * | 2014-04-14 | 2020-10-28 | アルビナス・オペレーションズ・インコーポレイテッドArvinas Operations, Inc. | イミド系タンパク質分解モジュレーター及び関連する使用方法 |
US9499514B2 (en) * | 2014-07-11 | 2016-11-22 | Celgene Corporation | Antiproliferative compounds and methods of use thereof |
CA2958867A1 (en) | 2014-08-22 | 2016-02-25 | Anjan THAKURTA | Methods of treating multiple myeloma with immunomodulatory compounds in combination with antibodies |
EP3204008A4 (en) * | 2014-10-07 | 2018-03-07 | Celgene Corporation | Use of biomarkers for predicting clinical sensitivity to cancer treatment |
CN105566290B (zh) | 2014-10-30 | 2020-05-22 | 康朴生物医药技术(上海)有限公司 | 异吲哚啉衍生物、其中间体、制备方法、药物组合物及应用 |
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CA3010801A1 (en) * | 2016-01-08 | 2017-07-13 | Celgene Corporation | Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies |
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