SE8400445D0 - Novel pharmaceutical active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives, their production and use - Google Patents

Novel pharmaceutical active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives, their production and use

Info

Publication number
SE8400445D0
SE8400445D0 SE8400445A SE8400445A SE8400445D0 SE 8400445 D0 SE8400445 D0 SE 8400445D0 SE 8400445 A SE8400445 A SE 8400445A SE 8400445 A SE8400445 A SE 8400445A SE 8400445 D0 SE8400445 D0 SE 8400445D0
Authority
SE
Sweden
Prior art keywords
octahydrobenzo
production
pharmaceutical active
quinoline derivatives
novel pharmaceutical
Prior art date
Application number
SE8400445A
Other languages
English (en)
Other versions
SE8400445L (sv
Inventor
M P Seiler
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8400445D0 publication Critical patent/SE8400445D0/sv
Publication of SE8400445L publication Critical patent/SE8400445L/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/08Aza-anthracenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8400445A 1983-02-01 1984-01-30 Nya farmaceutiska aktiva 1,2,3,4,4a,5,10,10a-oktahydrobenso(g)kinolinderivat, deras framstellning och anvendning SE8400445L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH56083 1983-02-01

Publications (2)

Publication Number Publication Date
SE8400445D0 true SE8400445D0 (sv) 1984-01-30
SE8400445L SE8400445L (sv) 1984-08-02

Family

ID=4189841

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8400445A SE8400445L (sv) 1983-02-01 1984-01-30 Nya farmaceutiska aktiva 1,2,3,4,4a,5,10,10a-oktahydrobenso(g)kinolinderivat, deras framstellning och anvendning

Country Status (17)

Country Link
US (1) US4692453A (sv)
JP (1) JPS59144761A (sv)
AU (1) AU571482B2 (sv)
BE (1) BE898761A (sv)
DE (1) DE3402601A1 (sv)
DK (1) DK40984A (sv)
FR (1) FR2540112B1 (sv)
GB (1) GB2134515B (sv)
IE (1) IE56653B1 (sv)
IL (1) IL70845A (sv)
IT (1) IT1199056B (sv)
LU (1) LU85191A1 (sv)
NL (1) NL8400259A (sv)
NZ (1) NZ206981A (sv)
PH (1) PH22782A (sv)
SE (1) SE8400445L (sv)
ZA (1) ZA84757B (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT393997B (de) * 1983-06-22 1992-01-10 Heidelberger Druckmasch Ag Vorrichtung zur entnahme von bedruckten bogen fuer deren begutachtung
WO1991000856A2 (en) * 1989-07-13 1991-01-24 The Upjohn Company (1,2n) and (3,2n)-carbocyclic-2-amino tetralin derivatives
US4939259A (en) * 1989-07-24 1990-07-03 Eli Lilly And Company 2-oxo-pyrido[2,3-g]quinoline derivatives
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
JPH06507906A (ja) * 1991-05-20 1994-09-08 ジ・アップジョン・カンパニー カルボキサミド−(3,2n)−カルボサイクリック−2−アミノテトラリン誘導体
US8129530B2 (en) * 2007-08-31 2012-03-06 H. Lundbeck A/S Catecholamine derivatives and prodrugs thereof
WO2009156458A1 (en) * 2008-06-27 2009-12-30 H. Lundbeck A/S Novel phenolic and catecholic amines and prodrugs thereof
JP7320507B2 (ja) 2017-11-24 2023-08-03 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639411A (en) * 1968-05-09 1972-02-01 Sterling Drug Inc 1-substituted-2-(phenyl or benzyl)-3- or 3 3 - piperidine(mono or dicarboxylic) acids and esters thereo fand octahydrobenzo(g) - quinolines and hexahydro-5h-inden (12-b)pyridines produced therefrom
US3839338A (en) * 1968-05-09 1974-10-01 W Michne 1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO{8 g{9 QUINOLINES
US3898235A (en) * 1970-12-02 1975-08-05 Sterling Drug Inc Octahydrobenzo {8 g{9 {0 quinolines and hexahydroindeno {8 1,2,b{9 {0 pyridines
ATE56958T1 (de) * 1981-10-16 1990-10-15 Sandoz Ag 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)chinolinderivate mit pharmazeutischer wirkung.

Also Published As

Publication number Publication date
GB8402358D0 (en) 1984-02-29
LU85191A1 (fr) 1984-10-24
IL70845A0 (en) 1984-05-31
AU2391184A (en) 1984-08-02
DE3402601A1 (de) 1984-08-02
SE8400445L (sv) 1984-08-02
DK40984D0 (da) 1984-01-30
AU571482B2 (en) 1988-04-21
US4692453A (en) 1987-09-08
PH22782A (en) 1988-12-12
FR2540112A1 (fr) 1984-08-03
GB2134515A (en) 1984-08-15
NL8400259A (nl) 1984-09-03
GB2134515B (en) 1986-07-02
DK40984A (da) 1984-08-02
NZ206981A (en) 1987-03-31
ZA84757B (en) 1985-09-25
BE898761A (fr) 1984-07-26
IE840209L (en) 1984-08-01
IT1199056B (it) 1988-12-30
IL70845A (en) 1986-09-30
IE56653B1 (en) 1991-10-23
JPS59144761A (ja) 1984-08-18
FR2540112B1 (fr) 1986-08-29
IT8447626A0 (it) 1984-02-01

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