SE8306370D0 - Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions - Google Patents

Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions

Info

Publication number
SE8306370D0
SE8306370D0 SE8306370A SE8306370A SE8306370D0 SE 8306370 D0 SE8306370 D0 SE 8306370D0 SE 8306370 A SE8306370 A SE 8306370A SE 8306370 A SE8306370 A SE 8306370A SE 8306370 D0 SE8306370 D0 SE 8306370D0
Authority
SE
Sweden
Prior art keywords
sub
hydrogen
intermediates
treatment
preparation
Prior art date
Application number
SE8306370A
Other languages
English (en)
Swedish (sv)
Inventor
R L Brattsand
B A Thalen
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Priority to SE8306370A priority Critical patent/SE8306370D0/xx
Publication of SE8306370D0 publication Critical patent/SE8306370D0/xx
Priority to DE8484850348T priority patent/DE3482588D1/de
Priority to EP84850348A priority patent/EP0143764B1/en
Priority to AT84850348T priority patent/ATE54153T1/de
Priority to JP59240888A priority patent/JPS60123496A/ja
Priority to US06/946,658 priority patent/US4820700A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8306370A 1983-11-18 1983-11-18 Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions SE8306370D0 (sv)

Priority Applications (6)

Application Number Priority Date Filing Date Title
SE8306370A SE8306370D0 (sv) 1983-11-18 1983-11-18 Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
DE8484850348T DE3482588D1 (de) 1983-11-18 1984-11-09 Androstan-17beta-carbonsaeureester, ein prozess und zwischenprodukte fuer ihre herstellung, kompositionen und methode zur behandlung inflammatorischer zustaende.
EP84850348A EP0143764B1 (en) 1983-11-18 1984-11-09 Novel androstane-17 beta-carboxylic acid esters, a process and intermediates for their preparation, composition and method for the treatment of inflammatory conditions
AT84850348T ATE54153T1 (de) 1983-11-18 1984-11-09 Androstan-17beta-carbonsaeureester, ein prozess und zwischenprodukte fuer ihre herstellung, kompositionen und methode zur behandlung inflammatorischer zustaende.
JP59240888A JPS60123496A (ja) 1983-11-18 1984-11-16 新規なアンドロスタン―１７β―カルボン酸エステルおよびその製法
US06/946,658 US4820700A (en) 1983-11-18 1987-01-05 Novel androstane-17β-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8306370A SE8306370D0 (sv) 1983-11-18 1983-11-18 Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions

Publications (1)

Publication Number Publication Date
SE8306370D0 true SE8306370D0 (sv) 1983-11-18

Family

ID=20353384

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8306370A SE8306370D0 (sv) 1983-11-18 1983-11-18 Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions

Country Status (6)

Country Link
US (1) US4820700A (xx)
EP (1) EP0143764B1 (xx)
JP (1) JPS60123496A (xx)
AT (1) ATE54153T1 (xx)
DE (1) DE3482588D1 (xx)
SE (1) SE8306370D0 (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8501693D0 (sv) * 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
SE8903914D0 (sv) 1989-11-22 1989-11-22 Draco Ab Oral composition for the treatment of inflammatory bowel diseases
US5643602A (en) * 1989-11-22 1997-07-01 Astra Aktiebolag Oral composition for the treatment of inflammatory bowel disease
HU221584B (hu) * 1993-01-08 2002-11-28 Aktiebolaget Astra Új vastagbél- (colon) vagy csípőbél- (ileum) specifikus, cukortartalmú szteroidszármazékok, ezeket tartalmazó gyógyszerkészítmények és előállításuk
US6166024A (en) * 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
BR9612309A (pt) * 1995-12-29 1999-07-13 Glaxo Group Ltd Composto uso de um composto composição farmacêutica formulação farmacêutica de aerossol combinação e processos para o tratamento de um indivíduo humano ou animal com uma condição anti-inflamatória e/ou alérgica e para a preparação de um composto
CA2260584C (en) * 1998-02-04 2007-07-31 Charlotte-Mecklenburg Hospital D/B/A Carolinas Medical Center Androsterone derivatives for inhibiting dna binding of ap-1 and airway smooth muscle proliferation
JP2010540612A (ja) * 2007-10-04 2010-12-24 アストラゼネカ・アクチエボラーグ グルココルチコイド活性を有するステロイド［３，２−ｃ］ピラゾール化合物
WO2009082342A1 (en) * 2007-12-20 2009-07-02 Astrazeneca Ab Steroid derivatives acting as glucocorticosteroid receptor agonists
WO2009108118A1 (en) * 2008-02-27 2009-09-03 Astrazeneca Ab 16 alpha, 17 alpa-acetal glucocorticosteroidal derivatives and their use
UY32521A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Combinación para emplear en el tratamiento de enfermedades respiratorias
UY32523A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32525A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32520A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
CH628355A5 (de) * 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
CH614960A5 (xx) * 1976-04-15 1979-12-28 Ciba Geigy Ag
CH634081A5 (en) * 1977-04-13 1983-01-14 Ciba Geigy Ag Process for the preparation of novel androstadiene-17beta-carboxylic acid esters
US4198336A (en) * 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. Chemical process for preparing androsta-4-ene 17α-carboxylic acids
US4198403A (en) * 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. 17 Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes

Also Published As

Publication number Publication date
DE3482588D1 (de) 1990-08-02
EP0143764A1 (en) 1985-06-05
JPS60123496A (ja) 1985-07-02
EP0143764B1 (en) 1990-06-27
US4820700A (en) 1989-04-11
JPH0533714B2 (xx) 1993-05-20
ATE54153T1 (de) 1990-07-15

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